BluGen: An Analytic Framework for Mission-Cyber Risk Assessment and Mitigation Recommendation

Systems security engineering (SSE) is a complex, manually intensive process, with implications for cost, time required, and repeatability/reproducibility. This paper describes BluGen, an analytic framework that generates risk plots and recommends prioritized mitigations for a target mission/system environment based on a stated level of threat and risk tolerance. The goal is to give working system security engineers a head start in their analysis. We describe BluGen in the context of Design Science Research and evaluate accordingly

Tradable Performance Standards in the Transportation Sector

Several tradable performance standard (TPS) programs have recently been implemented in the US transportation sector: regulations for greenhouse gas emissions from passenger cars and trucks (national), zero-emission vehicle programs (10 states), the Renewable Fuel Standard (national), and low-carbon fuel standards (two states). The primary motivations are to promote innovation, to address consumers’ undervaluation of efficiency, and to reduce externalities, such as air pollution and the risks of dependence on foreign oil. A TPS sets a standard of technology performance but leaves technology choice to the producers; it increases the relative costs of technologies with undesirable performance characteristics and lowers the costs of technologies with desirable characteristics. We review the TPS programs and compare TPS with carbon pricing. Whereas carbon pricing creates incentives for both output reduction and technology change, TPS programs do not fully internalize the costs of emissions, resulting in lower price effects on products and raising the total cost of emissions reductions compared with carbon pricing. However, a TPS provides stronger incentives for upstream innovation and technology transformation. We show that TPS programs are generally additive to the effects of carbon pricing, so the policies can be combined without sacrificing the efficiency properties achieved by pricing. Given that the expected carbon price may be too low to substantially affect transportation demand or technology change, combining TPS with a carbon price may be necessary to drive innovation and achieve a sustained low-carbon transformation in the sector

A Blended Value Proposition: Towards a Regional Sustainability Entrepreneurial Ecosystem Framework for the Social Solidarity Economy (SSE)

This extended abstract has been submitted for the Faculty of Business and Law Research Day 2022

Automated irrigation scheduling application of the north dakota agricultural weather network

During the last 30 years, the development of agricultural weather networks and other technologies have made scientific irrigation scheduling much easier to apply and use. However, at the present time the most frequent complaints by irrigators about scientific irrigation scheduling is that it has a steep learning curve, takes too much time to gather all the bits of information and they just don't have the time during the growing season. To address these concerns a site-specific irrigation scheduling program, accessible through the North Dakota Agricultural Weather Network (NDAWN)1 website, was developed. The irrigation scheduling application has become one of the most popular agricultural applications on the NDAWN website (http://ndawn.ndsu.nodak.edu). It is designed to increase proficiency in water usage of irrigators by calculating site-specific water deficiency in soil. The soil-water deficiency is calculated based on a selected field and the growth stage of a selected crop. The application interfaces with a Geographic Information System (GIS)2to select a specific field and thus obtain the geographic coordinates for the soil types and soil water holding capacity in the field. It also interfaces with the nearest NDAWN automated weather station to obtain meteorological information to automatically calculate crop water requirements on a daily basis of the crop in the selected field. The output is the daily checks and balances of the soil-water deficiency for the selected field

A National Study on the Effects of Concussion in Collegiate Athletes and US Military Service Academy Members: The NCAA-DoD Concussion Assessment, Research and Education (CARE) Consortium Structure and Methods

BACKGROUND: The natural history of mild traumatic brain injury (TBI) or concussion remains poorly defined and no objective biomarker of physiological recovery exists for clinical use. The National Collegiate Athletic Association (NCAA) and the US Department of Defense (DoD) established the Concussion Assessment, Research and Education (CARE) Consortium to study the natural history of clinical and neurobiological recovery after concussion in the service of improved injury prevention, safety and medical care for student-athletes and military personnel. OBJECTIVES: The objectives of this paper were to (i) describe the background and driving rationale for the CARE Consortium; (ii) outline the infrastructure of the Consortium policies, procedures, and governance; (iii) describe the longitudinal 6-month clinical and neurobiological study methodology; and (iv) characterize special considerations in the design and implementation of a multicenter trial. METHODS: Beginning Fall 2014, CARE Consortium institutions have recruited and enrolled 23,533 student-athletes and military service academy students (approximately 90% of eligible student-athletes and cadets; 64.6% male, 35.4% female). A total of 1174 concussions have been diagnosed in participating subjects, with both concussion and baseline cases deposited in the Federal Interagency Traumatic Brain Injury Research (FITBIR) database. CONCLUSIONS: Challenges have included coordinating regulatory issues across civilian and military institutions, operationalizing study procedures, neuroimaging protocol harmonization across sites and platforms, construction and maintenance of a relational database, and data quality and integrity monitoring. The NCAA-DoD CARE Consortium represents a comprehensive investigation of concussion in student-athletes and military service academy students. The richly characterized study sample and multidimensional approach provide an opportunity to advance the field of concussion science, not only among student athletes but in all populations at risk for mild TBI

Algorithms & experiments for the protein chain lattice fitting problem

ix, 47 leaves ; 29 cm.This study seeks to design algorithms that may be used to determine if a given lattice is a good approximation to a given rigid protein structure. Ideal lattice models discovered using our techniques may then be used in algorithms for protein folding and inverse protein folding. In this study we develop methods based on dynamic programming and branch and bound in an effort to identify “ideal” lattice models. To further our understanding of the concepts behind the methods we have utilized a simple cubic lattice for our analysis. The algorithms may be adapted to work on any lattice. We describe two algorithms. One for aligning the protein backbone to the lattice as a walk. This algorithm runs in polynomial time. The second algorithm for aligning a protein backbone as a path to the lattice. Both the algorithms seek to minimize the CRMS deviation of the alignment. The second problem was recently shown to be NP-Complete, hence it is highly unlikely that an efficient algorithm exists. The first algorithm gives a lower bound on the optimal solution to the second problem, and can be used in a branch and bound procedure. Further, we perform an empirical evaluation of our algorithm on proteins from the Protein Data Bank (PDB)

The Body in Isolation: The Physical Health Impacts of Incarceration in Solitary Confinement

We examine how solitary confinement correlates with self-reported adverse physical health outcomes, and how such outcomes extend the understanding of the health disparities associated with incarceration. Using a mixed methods approach, we find that solitary confinement is associated not just with mental, but also with physical health problems. Given the disproportionate use of solitary among incarcerated people of color, these symptoms are most likely to affect those populations. Drawing from a random sample of prisoners (n = 106) in long-term solitary confinement in the Washington State Department of Corrections in 2017, we conducted semi-structured, in-depth interviews; Brief Psychiatric Rating Scale (BPRS) assessments; and systematic reviews of medical and disciplinary files for these subjects. We also conducted a paper survey of the entire long-term solitary confinement population (n = 225 respondents) and analyzed administrative data for the entire population of prisoners in the state in 2017 (n = 17,943). Results reflect qualitative content and descriptive statistical analysis. BPRS scores reflect clinically significant somatic concerns in 15% of sample. Objective specification of medical conditions is generally elusive, but that, itself, is a highly informative finding. Using subjective reports, we specify and analyze a range of physical symptoms experienced in solitary confinement: (1) skin irritations and weight fluctuation associated with the restrictive conditions of solitary confinement; (2) un-treated and mis-treated chronic conditions associated with the restrictive policies of solitary confinement; (3) musculoskeletal pain exacerbated by both restrictive conditions and policies. Administrative data analyses reveal disproportionate rates of racial/ethnic minorities in solitary confinement. This analysis raises the stakes for future studies to evaluate comparative prevalence of objective medical diagnoses and potential causal mechanisms for the physical symptoms specified here, and for understanding differential use of solitary confinement and its medically harmful sequelae

National health and medical research council statement on electronic cigarettes: 2022 update

Introduction: Electronic cigarette (e-cigarette) use in Australia has rapidly increased since the 2017 National Health and Medical Research Council (NHMRC) Chief Executive Officer (CEO) statement on e-cigarettes. The type of products available and the demographic characteristics of people using these products have changed. New evidence has been published and there is growing concern among public health professionals about the increased use, particularly among young people who do not currently smoke combustible cigarettes. The combination of these issues led NHMRC to review the current evidence and provide an updated statement on e-cigarettes. In this article, we describe the comprehensive process used to review the evidence and develop the 2022 NHMRC CEO statement on electronic cigarettes. Main recommendations: E-cigarettes can be harmful; all e-cigarette users are exposed to chemicals and toxins that have the potential to cause adverse health effects. There are no health benefits of using e-cigarettes if you do not currently smoke tobacco cigarettes. Adolescents are more likely to try e-cigarettes if they are exposed to e-cigarettes on social media. Short term e-cigarette use may help some smokers to quit who have been previously unsuccessful with other smoking cessation aids. There are other proven safe and effective options available to help smokers to quit. Changes in management as a result of this statement: The evidence base for the harms of e-cigarette use has strengthened since the previous NHMRC statement. Significant gaps in the evidence base remain, especially about the longer term health harms of using e-cigarettes and the toxicity of many chemicals in e-cigarettes inhaled as an aerosol

West Nile Virus in Farmed Alligators

Seven alligators were submitted to the Tifton Veterinary Diagnostic and Investigational Laboratory for necropsy during two epizootics in the fall of 2001 and 2002. The alligators were raised in temperature-controlled buildings and fed a diet of horsemeat supplemented with vitamins and minerals. Histologic findings in the juvenile alligators were multiorgan necrosis, heterophilic granulomas, and heterophilic perivasculitis and were most indicative of septicemia or bacteremia. Histologic findings in a hatchling alligator were random foci of necrosis in multiple organs and mononuclear perivascular encephalitis, indicative of a viral cause. West Nile virus was isolated from submissions in 2002. Reverse transcription-polymerase chain reaction (RT-PCR) results on all submitted case samples were positive for West Nile virus for one of four cases associated with the 2001 epizootic and three of three cases associated with the 2002 epizootic. RT-PCR analysis was positive for West Nile virus in the horsemeat collected during the 2002 outbreak but negative in the horsemeat collected after the outbreak