46 research outputs found
STUDY ON INSPECTION OF THE PUTATIVE HYBRIDS BETWEEN TRACK-LACKING WILD MALE GAUR (BOS GAURUS) AND DOMESTIC FEMALE COW (BOS TAURUS) IN PHUOC BINH NATIONAL PARK, VIETNAM
Hybridization between wild and domestic bovine occurs widely due to the overlapping of the natural habitat of the wild and human farm animals. Due to the loss of habitat, the number of wild gaur (Bos gaurus) in Vietnam was in serious decline. Since 2009, a male wild gaur (Bos gaurus) has appeared and incorporated with female domestic cows (Bos taurus) in buffer zone Phuoc Binh National Park, on the border with Lam Dong and Ninh Thuan provinces. Then, several calves were born that carried some traits of wild gaur including physical characteristics and behaviors. These calves were supposed to be offspring between wild gaur and domestic cows. In previous study, the karyotypes of putative calves were identified with 2n = 58 and non-homologous chromosome 28 and 29 in these hybrids. In this study, we characterized the putative hybrids between track-lacking Bos gaurus and Bos taurus for breeding and preservation using Cytochrome b analysis, microsatellites and a novel marker growth hormone factor 1 (POU1F1). Cytochrome b analysis indicated the maternal lineage of the putative hybrids, with 100% nucleotide sequence identity. Microsatellite BM861 and sequence of ZFY gene region reveal Bos taurus chromosome Y origin was among the male putative hybrids. Importantly, the analysis of POU1F1 gene sequence on 1 chromosome showed efficacy in determining both Bos gaurus and Bos taurus lineage in the putative hybrids. The karyotyping results were confirmed by molecular analysis and our results provide a feasible way for detecting the putative hybrids between wild and domestic cattle in case of lacking the wild trace
TextANIMAR: Text-based 3D Animal Fine-Grained Retrieval
3D object retrieval is an important yet challenging task, which has drawn
more and more attention in recent years. While existing approaches have made
strides in addressing this issue, they are often limited to restricted settings
such as image and sketch queries, which are often unfriendly interactions for
common users. In order to overcome these limitations, this paper presents a
novel SHREC challenge track focusing on text-based fine-grained retrieval of 3D
animal models. Unlike previous SHREC challenge tracks, the proposed task is
considerably more challenging, requiring participants to develop innovative
approaches to tackle the problem of text-based retrieval. Despite the increased
difficulty, we believe that this task has the potential to drive useful
applications in practice and facilitate more intuitive interactions with 3D
objects. Five groups participated in our competition, submitting a total of 114
runs. While the results obtained in our competition are satisfactory, we note
that the challenges presented by this task are far from being fully solved. As
such, we provide insights into potential areas for future research and
improvements. We believe that we can help push the boundaries of 3D object
retrieval and facilitate more user-friendly interactions via vision-language
technologies.Comment: arXiv admin note: text overlap with arXiv:2304.0573
Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: A systematic analysis for the global burden of disease study 2017
© 2020 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Background: Previous attempts to characterise the burden of chronic respiratory diseases have focused only on specific disease conditions, such as chronic obstructive pulmonary disease (COPD) or asthma. In this study, we aimed to characterise the burden of chronic respiratory diseases globally, providing a comprehensive and up-to-date analysis on geographical and time trends from 1990 to 2017. Methods: Using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017, we estimated the prevalence, morbidity, and mortality attributable to chronic respiratory diseases through an analysis of deaths, disability-adjusted life-years (DALYs), and years of life lost (YLL) by GBD super-region, from 1990 to 2017, stratified by age and sex. Specific diseases analysed included asthma, COPD, interstitial lung disease and pulmonary sarcoidosis, pneumoconiosis, and other chronic respiratory diseases. We also assessed the contribution of risk factors (smoking, second-hand smoke, ambient particulate matter and ozone pollution, household air pollution from solid fuels, and occupational risks) to chronic respiratory disease-attributable DALYs. Findings: In 2017, 544·9 million people (95% uncertainty interval [UI] 506·9–584·8) worldwide had a chronic respiratory disease, representing an increase of 39·8% compared with 1990. Chronic respiratory disease prevalence showed wide variability across GBD super-regions, with the highest prevalence among both males and females in high-income regions, and the lowest prevalence in sub-Saharan Africa and south Asia. The age-sex-specific prevalence of each chronic respiratory disease in 2017 was also highly variable geographically. Chronic respiratory diseases were the third leading cause of death in 2017 (7·0% [95% UI 6·8–7·2] of all deaths), behind cardiovascular diseases and neoplasms. Deaths due to chronic respiratory diseases numbered 3 914 196 (95% UI 3 790 578–4 044 819) in 2017, an increase of 18·0% since 1990, while total DALYs increased by 13·3%. However, when accounting for ageing and population growth, declines were observed in age-standardised prevalence (14·3% decrease), age-standardised death rates (42·6%), and age-standardised DALY rates (38·2%). In males and females, most chronic respiratory disease-attributable deaths and DALYs were due to COPD. In regional analyses, mortality rates from chronic respiratory diseases were greatest in south Asia and lowest in sub-Saharan Africa, also across both sexes. Notably, although absolute prevalence was lower in south Asia than in most other super-regions, YLLs due to chronic respiratory diseases across the subcontinent were the highest in the world. Death rates due to interstitial lung disease and pulmonary sarcoidosis were greater than those due to pneumoconiosis in all super-regions. Smoking was the leading risk factor for chronic respiratory disease-related disability across all regions for men. Among women, household air pollution from solid fuels was the predominant risk factor for chronic respiratory diseases in south Asia and sub-Saharan Africa, while ambient particulate matter represented the leading risk factor in southeast Asia, east Asia, and Oceania, and in the Middle East and north Africa super-region. Interpretation: Our study shows that chronic respiratory diseases remain a leading cause of death and disability worldwide, with growth in absolute numbers but sharp declines in several age-standardised estimators since 1990. Premature mortality from chronic respiratory diseases seems to be highest in regions with less-resourced health systems on a per-capita basis. Funding: Bill & Melinda Gates Foundation
Safety and efficacy of fluoxetine on functional outcome after acute stroke (AFFINITY): a randomised, double-blind, placebo-controlled trial
Background
Trials of fluoxetine for recovery after stroke report conflicting results. The Assessment oF FluoxetINe In sTroke recoverY (AFFINITY) trial aimed to show if daily oral fluoxetine for 6 months after stroke improves functional outcome in an ethnically diverse population.
Methods
AFFINITY was a randomised, parallel-group, double-blind, placebo-controlled trial done in 43 hospital stroke units in Australia (n=29), New Zealand (four), and Vietnam (ten). Eligible patients were adults (aged ≥18 years) with a clinical diagnosis of acute stroke in the previous 2–15 days, brain imaging consistent with ischaemic or haemorrhagic stroke, and a persisting neurological deficit that produced a modified Rankin Scale (mRS) score of 1 or more. Patients were randomly assigned 1:1 via a web-based system using a minimisation algorithm to once daily, oral fluoxetine 20 mg capsules or matching placebo for 6 months. Patients, carers, investigators, and outcome assessors were masked to the treatment allocation. The primary outcome was functional status, measured by the mRS, at 6 months. The primary analysis was an ordinal logistic regression of the mRS at 6 months, adjusted for minimisation variables. Primary and safety analyses were done according to the patient's treatment allocation. The trial is registered with the Australian New Zealand Clinical Trials Registry, ACTRN12611000774921.
Findings
Between Jan 11, 2013, and June 30, 2019, 1280 patients were recruited in Australia (n=532), New Zealand (n=42), and Vietnam (n=706), of whom 642 were randomly assigned to fluoxetine and 638 were randomly assigned to placebo. Mean duration of trial treatment was 167 days (SD 48·1). At 6 months, mRS data were available in 624 (97%) patients in the fluoxetine group and 632 (99%) in the placebo group. The distribution of mRS categories was similar in the fluoxetine and placebo groups (adjusted common odds ratio 0·94, 95% CI 0·76–1·15; p=0·53). Compared with patients in the placebo group, patients in the fluoxetine group had more falls (20 [3%] vs seven [1%]; p=0·018), bone fractures (19 [3%] vs six [1%]; p=0·014), and epileptic seizures (ten [2%] vs two [<1%]; p=0·038) at 6 months.
Interpretation
Oral fluoxetine 20 mg daily for 6 months after acute stroke did not improve functional outcome and increased the risk of falls, bone fractures, and epileptic seizures. These results do not support the use of fluoxetine to improve functional outcome after stroke
Determining Optimal Gear Ratios of a Two-stage Helical Reducer for Getting Minimal Acreage of Cross Section
This article introduces a study on the optimal calculation of gear ratios of a two-stage helical reducer. In the study, the acreage of the cross section of the reducer was chosen as the objective function of the optimization problem. Also, the design equation for pitting resistance of a gear set was investigated. Furthermore, the equations on moment equilibrium condition of a two-stage helical reducer and their regular resistance condition were analysed. A computer program was performed to determine the optimal partial transmission ratios for getting the minimal acreage of the cross section of the system. From the results of the computer program, two models for determining the optimal gear ratios of a two-stage reducer were proposed. Using these models, the gear ratios can be calculated accurately in a simple way
Determining Optimal Gear Ratios of a Two-stage Helical Reducer for Getting Minimal Acreage of Cross Section
This article introduces a study on the optimal calculation of gear ratios of a two-stage helical reducer. In the study, the acreage of the cross section of the reducer was chosen as the objective function of the optimization problem. Also, the design equation for pitting resistance of a gear set was investigated. Furthermore, the equations on moment equilibrium condition of a two-stage helical reducer and their regular resistance condition were analysed. A computer program was performed to determine the optimal partial transmission ratios for getting the minimal acreage of the cross section of the system. From the results of the computer program, two models for determining the optimal gear ratios of a two-stage reducer were proposed. Using these models, the gear ratios can be calculated accurately in a simple way
Role of Upper Respiratory Microbiota and Virome in Childhood Rhinitis and Wheeze: Collegium Internationale Allergologicum Update 2021
10.1159/000513325INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY1824265-27
Activity Concentrations of Sr-90 and Cs-137 in Seawater and Sediment in the Gulf of Tonkin, Vietnam
In this study, we measured the activity concentrations of Cs-137 and Sr-90 in surface seawater and surface sediments at the Tra Co, Bach Long Vi, and Ky Anh locations in the Gulf of Tonkin, Vietnam, from December 2018 to October 2019. The average activity at the selected locations was 1.22, 1.43, and 1.33 Bq/m3 for Cs-137 and 0.88, 1.17, and 1.09 Bq/m3 for Sr-90 in surface seawater samples and 0.74, 1.01, and 0.81 Bq/kg dry for Cs-137 and 0.49, 0.49, and 0.43 Bq/kg dry for Sr-90 in sediment samples. The ratio of the average activity concentration (Cs-137/Sr-90) in the surface seawater was 1.42, 1.22, and 1.22 at the Tra Co, Bach Long Vi, and Ky Anh locations, respectively. These are somewhat low compared to the global ratios (1.6 and 1.8). Meanwhile, Cs-137/Sr-90 ratios in the sediment samples at the selected locations were 1.51, 2.06, and 1.88, respectively, which is equal to or greater than the corresponding value for global sedimentation according to the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR). Correlations between Sr-90, Cs-137, and organic carbon content were detected in this study. The results showed that Cs-137 has a high correlation with the organic carbon content in sediment, while Sr-90 has a low correlation