Development of Modern Trends in Higher and Secondary Professional School Based on Innovative Development

The article considers innovative processes taking place in modern socio-economic conditions in the system of higher and secondary professional education in the Russian Federation. The study points out negative factors that prevent the formation of innovative processes in the economy. They identify innovative ways of development in the system of higher and secondary professional schools and essential differences in the definition of significant trends of development. The study has defined a socially-oriented model as the most progressive model of innovative development of higher education institutions. It is the social-oriented model that allows us integrating scientific-research and professional-oriented assets creating an innovative environment in higher education. Other processes are typical for secondary vocational education, the main purpose of which is defined as providing the middle level of the Russian economy with highly skilled workers and specialists. The study has revealed that there are approach processes of the secondary vocational education system with production. Business structures are taking more active part in the organization of the educational process every year. In recent years, interregional centers of competence and vocational training centers have been created on the basis of professional educational organizations mean by innovative frameworks Keywords: innovation, higher education, secondary vocational education, educational institution

Specifics of the organization and conducting professional orientation work sverdlovsk region

Автор приводит результаты исследования 2012 года. Основное внимание уделено особенностям выбора будущего места учебы, профессиональным планам, анализу отношения выпускников к существующей системе профориентационной работы и их предложения по ее развитию. Материалы интересны работникам образования, ответственным за профориентацию, представителям органов власти, выпускникам школ и их родителям.The author cites the results of the survey realized in late 2012 among the Yekaterinburg and the Sverdlovsk region. The main focus is to note the peculiarities of the future study place choice and professional plans. The author analyzes in detail the attitude of Russian school leavers to the existing system of career guidance and their suggestions for its development. The data are interesting for the education system employees, for the responsible for the organization and management of career guidance, for the authorities of the RF, for the school leavers and their parents

Novel mechanism for temperature-independent transitions in flexible molecules: role of thermodynamic fluctuations

Novel physical mechanism is proposed for explanation of temperature-independent transition reactions in molecular systems. The mechanism becomes effective in the case of conformation transitions between quasi-isoenergetic molecular states. It is shown that at room temperatures, stochastic broadening of molecular energy levels predominates the energy of low frequency vibrations accompanying the transition. This leads to a cancellation of temperature dependence in the stochastically averaged rate constants. As an example, physical interpretation of temperature-independent onset of P2X_3 receptor desensitization in neuronal membranes is provided.Comment: 4 pages, 1 figur

Average professional educations of modern russia: trends, innovations

В статье рассматривается актуальный для современного этапа развития системы среднего профессионального образования элемент практико-ориентированности в организации образовательного процесса. Определена значимость опыта системы образовательных организаций СПО в развитии современного тренда — дульного образования.Article is devoted to the analysis of tendencies on average professional educations. The author analyzes features of the organization of dual education in the countries of Europe. Emphasizes the importance of the praktiko-focused principles for the organization of educational process in Russia. Significant characteristics for formation of competitiveness of graduates are defined

Gas Chromatographic Determination of Diacetylmorphine with Mass Spectrometric Detection

The possibility of determining diacetylmorphine traces in various matrices by gas chromatography with mass spectrometric detection is demonstrated. Diacetylmorphine can be reliably determined by gas chromatography-mass spectrometry in the range 0.02-7.5 μg/mL. A procedure is developed for the quantitative determination of diacetylmorphine and its concomitants, including acetylated opioid derivatives, in forensic samples. The detection limit for diacetylmorphine without preconcentration is 0.01 μg/mL. The detection limit in the selective-ion monitoring mode with preconcentration is 1 × 10 -4 ×g/mL

Partnership interaction of the state and civil society as a mechanism for the implementation of Ukraine’s humanitarian policy in the conditions of European integration

The article represents an attempt to analyze the landscape of partnership between government and civil society within the implementation of humanitarian policy in Ukraine and EU. Theoretical provisions of such partnerships are presented, and real state-of-the art in humanitarian space of the USA, EU, and Ukraine is investigated. Particularly, the phenomenon of precariat is considered through the lens of its role for civil society’ stability and designing effective humanitarian policies to improve social capital

Features of diagnostics of gastroesophageal and duodenogastric reflux in patients with complicated forms of peptic ulcer.

Purpose – to improve the results of surgical treatment of duodenal ulcer due to preoperative diagnosis of concomitant reflux disease and its correction. Before surgery, 46 patients with complicated forms of peptic  ulcer disease underwent pH monitoring and 23 – impedance-pH monitoring. Pathological gastroesophageal reflux was found in 58 cases. Before surgery, esophageal pH monitoring was performed in 46 patients with complicated forms of peptic ulcer disease. Against the background of hyper – and normacidity of the stomach in 39 patients pathological acidic gastroesophageal reflux disease with a significant increase of De Meester index was confirmed. Impedance-pH monitoring was performed before surgery in 23 patients with complicated forms of peptic ulcer and concomitant gastroesophageal reflux. Erosive form of gastroesophageal reflux disease was confirmed endoscopically in all patients with hyperacidity (17) and normal acidity (6) of the stomach. In 19 cases pathological gastroesophageal reflux disease was found. In 13 cases the cause of disorders in anti-reflux barrier was a diaphragmatic hernia of I-II degree. Gastroesophageal reflux disease was caused by increased intragastric pressure due to ulcer stenosis in 6 patients. pH- monitoring in patients with acidic gastroesophageal reflux allows to establish a pathological or physiological reflux. Conducting impedance-pH monitoring allows to determine the number of reflux episodes and their qualitative characteristics (acidic or alkaline; liquid, gas or mixed), as well as to determine the indications for a differentiated approach in the treatment of gastroesophageal reflux

Endoscopic endonasal approaches to the skull base tumors: minimally-invasive approach with achievement of radicality. Our experience

Objective: to optimize surgical tactic of endoscopic endonasal transsphenoidal (EET) approaches in cases of tumors with intra- and extracranial extension.Material and methods. For the period of 2013–2019, we retrospectively reviewed 39 patients with tumors of intra-extra skull base location or just extracranial extension. Tumor location and pathology: tumors in pterygopalatine fossa (paraganglioma, carcinoma, neurilemmoma, neurofibroma, chondrosarcoma) — 10 (25.6 %), pituitary adenomas with sphenoid sinus and/or parasellar extension — 14 (35.9 %), sphenoid sinus tumors (carcinoma, neurilemmoma, fibrous dysplasia, angiofibroma, esthesioneuroblastoma) — 8 (20.5 %), petroclival tumors — 6 (15.4 %): hemangiopericytoma — 1, clival tumors — 5 (chordoma), sella turcica lesion with posterior clinoid recess extension (osteoma) – 1 (2.5 %). The extended EET approaches used were as follows: EET + transpterygoid approach — 22 (56.4 %) (in 4 (18.1 %) cases transmaxillary approach was additionally used), extended EET + transclival approach — 4 (10.2 %), EET + transcavernous approach — 2 (5.1 %), EET + transethmoidal approach — 11 (28.2 %). In all cases, we used Karl Storz rigid 4mm 18cm with 0 and 30-degree angled optics. The extent of resection was determined based on routine postoperative CT scans performed within 24 hours after surgery. The volume of resection was evaluated using gadolinium. Gross total resection was defined as the resection of 100 % of the target lesion, subtotal resection as less than 100 % volumetric reduction of the lesion on postoperative CT scans. Further follow-up was done in three, six months and 1 year after surgery, then annually by MRI scanning with gadolinium.Results. Gross total resection was achieved in 7 (77.8 %) cases of tumor in pterygopalatine fossa. In cases of pituitary adenomas with Knosp 3, Knosp 4 cavernous sinus extension, gross total resection was achieved in 7 (53.8 %) individuals. Sphenoid sinus tumors were totally removed in 5 (62.5 %) cases. Subtotal resection was achieved in 11 (28.2 %) cases. Partial resection was achieved in 8 (20.5 %) cases. Postoperative complications were observed in 5 (12.1 %) cases.Conclusions Transethmoidal extended endoscopic endonasal approach is sufficient and good to access the anterior wall of the cavernous sinus improving visualization and better removing of cavernous sinus pathology extension. Transpterygoid extended endoscopic endonasal approach provides sufficient visualization of pterygopalatine fossa, petroclival region. Transmaxillary extension allows reaching the subtemporal region