14 research outputs found
Comprehensive Screening for COVID-19 at St. Petersburg Oncology Centre
Background. Clinical reports on the coronavirus disease 2019 (COVID-19) suggest its higher incidence and worse outcomes in cancer patients. Considering a rapid pace of the severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) pandemic, more data on the risk of contagion and syndrome course is required with this patient group.Aim. Estimation of the infection rate in cancer patients managed at the Oncology Centre.Materials and methods. This retrospective study included cancer patients managed at the Oncology Centre between 9 April 2020 and 27 May 2020 and routinely tested for SARS-CoV-2 in polymerase chain reaction (PCR) assays and/or COVID-19 in chest computed tomography (CT).Results and discussion. A total of 2,628 patients were included in the study, with 119 (4.5 %) confirmed to have COVID-19; 45/119 were PCR-positive, 95/119 had viral pneumonia in CT, 21/119 were positive for both tests. A total of 47.9 % cases were asymptomatic, 11.8 % revealed a mild single-symptom disease. COVID-19 ended in death in 2 (2.5 %) of 80 cases with a known outcome. In PCR results of both patient and staff screening, the virus detection rate was 3.0 % and 2.4 %, respectively (p = 0.33).Conclusion. A COVID-19 screening revealed no significant difference in the risk of contagion between cancer patients and staff of the Oncology Centre. PCR tests may perform false negative for COVID-19 in cancer patients and should be coupled with CT scanning. The infection is asymptomatic or clinically mild in most other cases
Molecular dynamic simulations of glycine amino acid association with potassium and sodium ions in explicit solvent
Molecular dynamics-based refinement of nanodiamond size measurements obtained with dynamic light scattering
Internationalization of Anti-Islamist Discourse and Creation of a Regional Antiterrorism Mechanism: The Initiative of Mubarakβs Egypt
Cervical myelopathy due to ossification of the transverse atlantal ligament: A Caucasian case report operated on and literature analysis
Vertebral artery injury and severely displaced odontoid fracture: the case for early reduction
ΠΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ½ΠΎΠ΅ ΠΎΠ±ΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ Π½Π° COVID-19 Π² ΠΠ½ΠΊΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΌ ΡΠ΅Π½ΡΡΠ΅ Π‘Π°Π½ΠΊΡ-ΠΠ΅ΡΠ΅ΡΠ±ΡΡΠ³Π°
Background. Clinical reports on the coronavirus disease 2019 (COVID-19) suggest its higher incidence and worse outcomes in cancer patients. Considering a rapid pace of the severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) pandemic, more data on the risk of contagion and syndrome course is required with this patient group.Aim. Estimation of the infection rate in cancer patients managed at the Oncology Centre.Materials and methods. This retrospective study included cancer patients managed at the Oncology Centre between 9 April 2020 and 27 May 2020 and routinely tested for SARS-CoV-2 in polymerase chain reaction (PCR) assays and/or COVID-19 in chest computed tomography (CT).Results and discussion. A total of 2,628 patients were included in the study, with 119 (4.5 %) confirmed to have COVID-19; 45/119 were PCR-positive, 95/119 had viral pneumonia in CT, 21/119 were positive for both tests. A total of 47.9 % cases were asymptomatic, 11.8 % revealed a mild single-symptom disease. COVID-19 ended in death in 2 (2.5 %) of 80 cases with a known outcome. In PCR results of both patient and staff screening, the virus detection rate was 3.0 % and 2.4 %, respectively (p = 0.33).Conclusion. A COVID-19 screening revealed no significant difference in the risk of contagion between cancer patients and staff of the Oncology Centre. PCR tests may perform false negative for COVID-19 in cancer patients and should be coupled with CT scanning. The infection is asymptomatic or clinically mild in most other cases.ΠΠ²Π΅Π΄Π΅Π½ΠΈΠ΅. ΠΡΡΠ΅ΡΡ ΠΎ ΠΊΠΎΡΠΎΠ½Π°Π²ΠΈΡΡΡΠ½ΠΎΠΉ Π±ΠΎΠ»Π΅Π·Π½ΠΈ 2019 (COVID-19) Ρ ΠΎΠ½ΠΊΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
Π±ΠΎΠ»ΡΠ½ΡΡ
ΠΏΡΠ΅Π΄ΠΏΠΎΠ»Π°Π³Π°ΡΡ Π±ΠΎΠ»Π΅Π΅ Π²ΡΡΠΎΠΊΡΡ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π΅ΠΌΠΎΡΡΡ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠ΅ΠΉ ΠΈ Ρ
ΡΠ΄ΡΠΈΠ΅ ΠΈΡΡ
ΠΎΠ΄Ρ Π² ΡΡΠΎΠΉ Π³ΡΡΠΏΠΏΠ΅. Π£ΡΠΈΡΡΠ²Π°Ρ Π±ΡΡΡΡΠΎΠ΅ ΡΠ°ΡΠΏΡΠΎΡΡΡΠ°Π½Π΅Π½ΠΈΠ΅ ΡΡΠΆΠ΅Π»ΠΎΠ³ΠΎ ΠΎΡΡΡΠΎΠ³ΠΎ ΡΠ΅ΡΠΏΠΈΡΠ°ΡΠΎΡΠ½ΠΎΠ³ΠΎ ΡΠΈΠ½Π΄ΡΠΎΠΌΠ° ΠΊΠΎΡΠΎΠ½Π°Π²ΠΈΡΡΡΠ° 2 (SARS-CoV-2), Π½Π΅ΠΎΠ±Ρ
ΠΎΠ΄ΠΈΠΌΠ° Π΄ΠΎΠΏΠΎΠ»Π½ΠΈΡΠ΅Π»ΡΠ½Π°Ρ ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΡ ΠΎ ΡΠΈΡΠΊΠ°Ρ
Π·Π°ΡΠ°ΠΆΠ΅Π½ΠΈΡ ΠΈ ΡΠ΅ΡΠ΅Π½ΠΈΠΈ COVID-19 Ρ ΡΡΠΈΡ
ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ².Π¦Π΅Π»Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ. Π¦Π΅Π»ΡΡ ΡΡΠΎΠ³ΠΎ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π±ΡΠ»ΠΎ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΡΠ°ΡΡΠΎΡΡ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΈ Ρ ΠΎΠ½ΠΊΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
Π±ΠΎΠ»ΡΠ½ΡΡ
, ΠΏΡΠΎΡ
ΠΎΠ΄ΡΡΠΈΡ
Π»Π΅ΡΠ΅Π½ΠΈΠ΅ Π² ΠΎΠ½ΠΊΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΌ ΡΠ΅Π½ΡΡΠ΅.ΠΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. ΠΡ ΡΠ΅ΡΡΠΎΡΠΏΠ΅ΠΊΡΠΈΠ²Π½ΠΎ ΠΏΡΠΎΠ°Π½Π°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π»ΠΈ ΠΊΠΎΠ³ΠΎΡΡΡ Π±ΠΎΠ»ΡΠ½ΡΡ
ΡΠ°ΠΊΠΎΠΌ, ΠΊΠΎΡΠΎΡΡΠ΅ Π½Π°Π±Π»ΡΠ΄Π°Π»ΠΈΡΡ ΠΈ ΠΏΡΠΎΡ
ΠΎΠ΄ΠΈΠ»ΠΈ Π»Π΅ΡΠ΅Π½ΠΈΠ΅ Π² Π½Π°ΡΠ΅ΠΌ ΠΎΠ½ΠΊΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΌ ΡΠ΅Π½ΡΡΠ΅ Ρ 9 Π°ΠΏΡΠ΅Π»Ρ 2020 ΠΏΠΎ 27 ΠΌΠ°Ρ 2020 Π³ΠΎΠ΄Π° ΠΈ ΡΠ΅Π³ΡΠ»ΡΡΠ½ΠΎ ΡΠ΅ΡΡΠΈΡΠΎΠ²Π°Π»ΠΈΡΡ Π½Π° SARS-CoV-2 Ρ ΠΏΠΎΠΌΠΎΡΡΡ Π°Π½Π°Π»ΠΈΠ·Π° ΠΏΠΎΠ»ΠΈΠΌΠ΅ΡΠ°Π·Π½ΠΎΠΉ ΡΠ΅ΠΏΠ½ΠΎΠΉ ΡΠ΅Π°ΠΊΡΠΈΠΈ (ΠΠ¦Π ) ΠΈ/ΠΈΠ»ΠΈ COVID-19 Π½Π° ΠΊΠΎΠΌΠΏΡΡΡΠ΅ΡΠ½ΠΎΠΉ ΡΠΎΠΌΠΎΠ³ΡΠ°ΡΠΈΠΈ (ΠΠ’) Π³ΡΡΠ΄Π½ΠΎΠΉ ΠΊΠ»Π΅ΡΠΊΠΈ.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΈ ΠΎΠ±ΡΡΠΆΠ΄Π΅Π½ΠΈΠ΅. Π Π°Π½Π°Π»ΠΈΠ· Π±ΡΠ»ΠΈ Π²ΠΊΠ»ΡΡΠ΅Π½Ρ 2628 ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ², Ρ 119 (4,5 %) ΠΈΠ· ΠΊΠΎΡΠΎΡΡΡ
Π±ΡΠ» ΠΎΠ±Π½Π°ΡΡΠΆΠ΅Π½ COVID-19; 45/119 Π±ΡΠ»ΠΈ ΠΠ¦Π -ΠΏΠΎΠ»ΠΎΠΆΠΈΡΠ΅Π»ΡΠ½ΡΠΌΠΈ, 95/119 ΠΈΠΌΠ΅Π»ΠΈ Π²ΠΈΡΡΡΠ½ΡΡ ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΡ Π½Π° ΠΊΠΎΠΌΠΏΡΡΡΠ΅ΡΠ½ΠΎΠΉ ΡΠΎΠΌΠΎΠ³ΡΠ°ΡΠΈΠΈ, ΠΈ ΠΎΠ±Π° ΡΠ΅ΡΡΠ° Π±ΡΠ»ΠΈ ΠΏΠΎΠ»ΠΎΠΆΠΈΡΠ΅Π»ΡΠ½ΡΠΌΠΈ Ρ 21/119. Π ΠΎΠ±ΡΠ΅ΠΉ ΡΠ»ΠΎΠΆΠ½ΠΎΡΡΠΈ 47,9 % ΡΠ»ΡΡΠ°Π΅Π² Π±ΡΠ»ΠΈ Π±Π΅ΡΡΠΈΠΌΠΏΡΠΎΠΌΠ½ΡΠΌΠΈ, Π° Π² 11,8 % ΡΠ»ΡΡΠ°Π΅Π² Π±ΡΠ»Π° Π»Π΅Π³ΠΊΠ°Ρ ΡΠΎΡΠΌΠ° COVID-19 Ρ ΠΎΠ΄Π½ΠΈΠΌ ΡΠΈΠΌΠΏΡΠΎΠΌΠΎΠΌ. COVID-19 Π·Π°ΠΊΠΎΠ½ΡΠΈΠ»ΡΡ ΡΠΌΠ΅ΡΡΠ΅Π»ΡΠ½ΡΠΌ ΠΈΡΡ
ΠΎΠ΄ΠΎΠΌ Π² 2 (2,5 %) ΠΈΠ· 80 ΡΠ»ΡΡΠ°Π΅Π² Ρ ΠΈΠ·Π²Π΅ΡΡΠ½ΡΠΌ ΠΈΡΡ
ΠΎΠ΄ΠΎΠΌ. ΠΠ° ΠΎΡΠ½ΠΎΠ²Π°Π½ΠΈΠΈ ΠΎΠ΄Π½ΠΎΠ³ΠΎ ΡΠΎΠ»ΡΠΊΠΎ ΡΠ΅ΡΡΠ° ΠΠ¦Π , ΠΊΠΎΡΠΎΡΡΠΉ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π»ΡΡ Π΄Π»Ρ ΡΠΊΡΠΈΠ½ΠΈΠ½Π³Π° ΠΊΠ°ΠΊ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ², ΡΠ°ΠΊ ΠΈ ΠΏΠ΅ΡΡΠΎΠ½Π°Π»Π°, ΡΡΠΎΠ²Π΅Π½Ρ ΠΎΠ±Π½Π°ΡΡΠΆΠ΅Π½ΠΈΡ Π²ΠΈΡΡΡΠΎΠ² ΡΡΠ΅Π΄ΠΈ ΠΏΡΠΎΡΠ΅ΡΡΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
Π»ΠΈΡ ΡΠΎΡΡΠ°Π²ΠΈΠ» 3,0 ΠΈ 2,4 % ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²Π΅Π½Π½ΠΎ (p = 0,33).ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. Π‘ΠΊΡΠΈΠ½ΠΈΠ½Π³ ΠΎΠ½ΠΊΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
Π±ΠΎΠ»ΡΠ½ΡΡ
Π½Π° COVID-19 Π² Π½Π°ΡΠ΅ΠΉ ΠΊΠ»ΠΈΠ½ΠΈΠΊΠ΅ ΠΏΠΎΠΊΠ°Π·ΡΠ²Π°Π΅Ρ, ΡΡΠΎ ΡΠΈΡΠΊ Π·Π°ΡΠ°ΠΆΠ΅Π½ΠΈΡ ΡΡΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎ Π½Π΅ ΠΎΡΠ»ΠΈΡΠ°Π΅ΡΡΡ ΠΎΡ ΡΠ°ΠΊΠΎΠ²ΠΎΠ³ΠΎ Ρ ΠΏΠ΅ΡΡΠΎΠ½Π°Π»Π° ΠΊΠ»ΠΈΠ½ΠΈΠΊΠΈ. ΠΠ΄Π½Π° ΡΠΎΠ»ΡΠΊΠΎ ΠΠ¦Π ΠΌΠΎΠΆΠ΅Ρ ΠΏΡΠΎΠΏΡΡΡΠΈΡΡ ΠΌΠ½ΠΎΠ³ΠΈΠ΅ ΡΠ»ΡΡΠ°ΠΈ COVID-19 Ρ ΠΎΠ½ΠΊΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
Π±ΠΎΠ»ΡΠ½ΡΡ
, ΠΈ Π΅Π³ΠΎ ΡΠ»Π΅Π΄ΡΠ΅Ρ ΡΠΎΡΠ΅ΡΠ°ΡΡ Ρ ΠΠ’. ΠΠ½ΡΠ΅ΠΊΡΠΈΡ ΠΏΡΠΎΡΠ΅ΠΊΠ°Π΅Ρ Π±Π΅ΡΡΠΈΠΌΠΏΡΠΎΠΌΠ½ΠΎ ΠΈΠ»ΠΈ Π² Π±ΠΎΠ»ΡΡΠΈΠ½ΡΡΠ²Π΅ ΡΠ»ΡΡΠ°Π΅Π² ΠΈΠΌΠ΅Π΅Ρ ΠΌΠΈΠ½ΠΈΠΌΠ°Π»ΡΠ½ΡΠ΅ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΏΡΠΎΡΠ²Π»Π΅Π½ΠΈΡ