My boy builds coffins. Future memories of your loved ones

The research is focus on the concept of storytelling associated with product design, trying to investigate new ways of designing and a possible future scenario related to the concept of death. MY BOY BUILDS COFFINS is a gravestone made using a combination of cremation’s ashes and resin. It is composed by a series of holes in which the user can stitch a text, in order to remember the loved one. The stitching need of a particular yarn produced in Switzerland using some parts of human body. Project also provides another version which uses LED lights instead of the yarn. The LEDs - thanks to an inductive coupling - will light when It will be posed in the hole. The gravestone can be placed where you want, as if it would create a little altar staff at home. In this way, there is a real connection between the user and the dearly departed

Performance Testing of Distributed Component Architectures

Performance characteristics, such as response time, throughput andscalability, are key quality attributes of distributed applications. Current practice,however, rarely applies systematic techniques to evaluate performance characteristics.We argue that evaluation of performance is particularly crucial in early developmentstages, when important architectural choices are made. At first glance, thiscontradicts the use of testing techniques, which are usually applied towards the endof a project. In this chapter, we assume that many distributed systems are builtwith middleware technologies, such as the Java 2 Enterprise Edition (J2EE) or theCommon Object Request Broker Architecture (CORBA). These provide servicesand facilities whose implementations are available when architectures are defined.We also note that it is the middleware functionality, such as transaction and persistenceservices, remote communication primitives and threading policy primitives,that dominates distributed system performance. Drawing on these observations, thischapter presents a novel approach to performance testing of distributed applications.We propose to derive application-specific test cases from architecture designs so thatthe performance of a distributed application can be tested based on the middlewaresoftware at early stages of a development process. We report empirical results thatsupport the viability of the approach

GPS vertical axis performance enhancement for helicopter precision landing approach

Several areas were investigated for improving vertical accuracy for a rotorcraft using the differential Global Positioning System (GPS) during a landing approach. Continuous deltaranging was studied and the potential improvement achieved by estimating acceleration was studied by comparing the performance on a constant acceleration turn and a rough landing profile of several filters: a position-velocity (PV) filter, a position-velocity-constant acceleration (PVAC) filter, and a position-velocity-turning acceleration (PVAT) filter. In overall statistics, the PVAC filter was found to be most efficient with the more complex PVAT performing equally well. Vertical performance was not significantly different among the filters. Satellite selection algorithms based on vertical errors only (vertical dilution of precision or VDOP) and even-weighted cross-track and vertical errors (XVDOP) were tested. The inclusion of an altimeter was studied by modifying the PVAC filter to include a baro bias estimate. Improved vertical accuracy during degraded DOP conditions resulted. Flight test results for raw differential results excluding filter effects indicated that the differential performance significantly improved overall navigation accuracy. A landing glidepath steering algorithm was devised which exploits the flexibility of GPS in determining precise relative position. A method for propagating the steering command over the GPS update interval was implemented

Simulation and analysis of differential global positioning system for civil helicopter operations

A Differential Global Positioning System (DGPS) computer simulation was developed, to provide a versatile tool for assessing DGPS referenced civil helicopter navigation. The civil helicopter community will probably be an early user of the GPS capability because of the unique mission requirements which include offshore exploration and low altitude transport into remote areas not currently served by ground based Navaids. The Monte Carlo simulation provided a sufficiently high fidelity dynamic motion and propagation environment to enable accurate comparisons of alternative differential GPS implementations and navigation filter tradeoffs. The analyst has provided the capability to adjust most aspects of the system, the helicopter flight profile, the receiver Kalman filter, and the signal propagation environment to assess differential GPS performance and parameter sensitivities. Preliminary analysis was conducted to evaluate alternative implementations of the differential navigation algorithm in both the position and measurement domain. Results are presented to show that significant performance gains are achieved when compared with conventional GPS but that differences due to DGPS implementation techniques were small. System performance was relatively insensitive to the update rates of the error correction information

Suspended between armageddon and immortality? A sociology for the 21st century

by Elena Denaro, PhD Student The first evening of Cumberland Lodge kicked off to a roaring start: an inspirational opening presentation by Craig Calhoun (Director of the LSE) followed by our first panel session on ‘Digital Futures’ with a trio of professors: Lord Anthony Giddens (Former Director of the LSE), and the department’s own Judy Wajcman and Nigel Dodd. Despite the late hour, the room was buzzing with thought-provoking ideas; about the future of the world, the impact of technology, how social theory can help us address the problems of the present and future, and how sociology as a discipline could position itself in the future

Protein kinase a distribution differentiates human glioblastoma from brain tissue

Brain tumor glioblastoma has no clear molecular signature and there is no effective therapy. In rodents, the intracellular distribution of the cyclic AMP (cAMP)-dependent protein kinase (Protein kinase A, PKA) R2Alpha subunit was previously shown to differentiate tumor cells from healthy brain cells. Now, we aim to validate this observation in human tumors. The distribution of regulatory (R1 and R2) and catalytic subunits of PKA was examined via immunohistochemistry and Western blot in primary cell cultures and biopsies from 11 glioblastoma patients. Data were compared with information obtained from 17 other different tumor samples. The R1 subunit was clearly detectable only in some samples. The catalytic subunit was variably distributed in the different tumors. Similar to rodent tumors, all human glioblastoma specimens showed perinuclear R2 distribution in the Golgi area, while it was undetectable outside the tumor. To test the effect of targeting PKA as a therapeutic strategy, the intracellular cyclic AMP concentration was modulated with different agents in four human glioblastoma cell lines. A significant increase in cell death was detected after increasing cAMP levels or modulating PKA activity. These data raise the possibility of targeting the PKA intracellular pathway for the development of diagnostic and/or therapeutic tools for human glioblastoma