73 research outputs found
Detección de patógenos de importancia epidemiológica en cerdos ferales de Chihuahua y Durango, México
This study aimed to evaluate in feral pigs the presence of Salmonella spp (Spp), porcine reproductive and respiratory syndrome virus (PRRSV), porcine circovirus type 2 (PCV2), swine influenza virus (SIV), porcine epidemic diarrhea virus (PEDV), Mycoplasma hyopneumoniae (Mhyo) and Actinobacillus pleuropneumoniae (App). The samples were obtained from pigs in the states of Chihuahua and Durango, Mexico. The tests analyzed for the animals from Chihuahua were nasal swabs for SIV, rectal swabs for Spp and PEDV, serum for PRRSV and PCV2, lung, liver, and lymph nodes for Spp, SIV, PRRSV, and PCV2, as well as serum for serological tests. From animals in the state of Durango, the following was collected: nasal swabs for SIV, rectal swabs for Spp and PEDV, and serum for PCV2 for molecular and serological studies. The molecular results in both states showed samples positive for PCV2, 73.3 % in Chihuahua and 91.3 % in Durango; likewise, two positive samples were obtained for Spp in the state of Chihuahua (13.3 %) and one in Durango (6.6 %), for SIV there were two positive (8.7 %) in Durango. For PRRSV and PEDV, samples were negative in both states. Serological results in pigs from the two states showed positivity for PCV2, Spp, and App. Samples were negative for PRRSV, PEDV, and Mhyo in both states. It is important to highlight the molecular and serological detection of feral pigs positive for various infectious agents important in pig production with zoosanitary repercussions on public health, which implies an epidemiological relevance of these animals in the context of “one health”.El objetivo de este trabajo fue evaluar en cerdos ferales la presencia de Salmonella spp (Spp), el virus del síndrome reproductivo y respiratorio porcino (VPRRS), circovirus porcino tipo 2 (PCV2), virus de influenza porcina (VIP), virus de diarrea epidémica porcina (VDEP), Mycoplasma hyopneumoniae (Mhyo) y Actinobacillus pleuropneumoniae (App). Las muestras se obtuvieron de cerdos en los estados de Chihuahua y Durango, México. Las pruebas analizadas para los animales de Chihuahua fueron hisopado nasal para VIP, hisopado rectal para Spp y VDEP, suero para VPRRS y PCV2, pulmón, hígado y linfonodos para Spp, VIP, VPRRS y PCV2, así como suero para pruebas serológicas. De los animales del estado de Durango se recolectó hisopado nasal para VIP, hisopado rectal para Spp y VDEP, y suero para PCV2 para estudios moleculares y serológicos. Los resultados moleculares en ambos estados mostraron muestras positivas para PCV2, 73.3 % en Chihuahua y 91.3 % para Durango, de igual forma se obtuvieron dos muestras positivas para Spp en el estado de Chihuahua (13.3 %) y una en Durango (6.6 %), para VIP hubo dos positivas (8.7 %) en Durango. Para VPRRS y VDEP, las muestras fueron negativas en ambos estados. Los resultados serológicos en cerdos de los dos estados mostraron positividad para PCV2, Spp y App. Las muestras fueron negativas para VPRRS, VDEP y Mhyo en ambos estados. Es importante remarcar la detección molecular y serológica de cerdos ferales positivos a diversos agentes infecciosos importantes en la producción porcina con repercusiones zoosanitarias en la salud pública, que implica una relevancia epidemiológica de estos animales en el contexto de “una salud”
Automated Speckle Interferometry of Known Binaries
Astronomers have been measuring the separations and position angles between
the two components of binary stars since William Herschel began his
observations in 1781. In 1970, Anton Labeyrie pioneered a method, speckle
interferometry, that overcomes the usual resolution limits induced by
atmospheric turbulence by taking hundreds or thousands of short exposures and
reducing them in Fourier space. Our 2022 automation of speckle interferometry
allowed us to use a fully robotic 1.0-meter PlaneWave Instruments telescope,
located at the El Sauce Observatory in the Atacama Desert of Chile, to obtain
observations of many known binaries with established orbits. The long-term
objective of these observations is to establish the precision, accuracy, and
limitations of this telescope's automated speckle interferometry measurements.
This paper provides an early overview of the Known Binaries Project and provide
example results on a small-separation (0.27") binary, WDS 12274-2843 B 228
Propagación de plantas nativas para la recuperación de áreas degradadas: Opción para mejorar ecosistemas
La pérdida de la cubierta vegetal contribuye al deterioro de los ecosistemas. La reducción de la cubierta vegetal aumenta los escurrimientos del agua de lluvia y por lo tanto la erosión del suelo. Este deterioro causa una reducción en los servicios y productos de los ecosistemas. Si bien existe tecnología para recuperar la vegetación, generalmente es con especies introducidas que a largo plazo pueden causar problemas más complejos. Actualmente urgen paquetes tecnológicos que incluyan mayores opciones de especies nativas que puedan usarse como forrajeras, fitorremediadoras, estabilizadoras de suelo ó materia prima en industrias específicas, entre otros. La flora del estado de Chihuahua posee un gran número de especies nativas de importancia económica que pueden ser utilizados en la recuperación de la cobertura vegetal. Por éste motivo, diversas instituciones en el estado de Chihuahua han unido esfuerzos a través de diversos proyectos encaminados al desarrollo de paquetes tecnológicos para la propagación de plantas nativas. Una de las metas a largo plazo de éstos proyectos es el registro del genoma de plantas nativas. La aplicación de resultados de éstos esfuerzos ayudaran a mitigar el deterioro de los ecosistemas y contribuiran a sustentar sistemas de producción naturales y humanos en el estado.
DOI: https://doi.org/10.54167/tecnociencia.v1i3.6
A global observational analysis to understand changes in air quality during exceptionally low anthropogenic emission
This global study, which has been coordinated by the World Meteorological Organization Global Atmospheric Watch (WMO/GAW) programme, aims to understand the behaviour of key air pollutant species during the COVID-19 pandemic period of exceptionally low emissions across the globe. We investigated the effects of the differences in both emissions and regional and local meteorology in 2020 compared with the period 2015–2019. By adopting a globally consistent approach, this comprehensive observational analysis focuses on changes in air quality in and around cities across the globe for the following air pollutants PM2.5, PM10, PMC (coarse fraction of PM), NO2, SO2, NOx, CO, O3 and the total gaseous oxidant (OX = NO2 + O3) during the pre-lockdown, partial lockdown, full lockdown and two relaxation periods spanning from January to September 2020. The analysis is based on in situ ground-based air quality observations at over 540 traffic, background and rural stations, from 63 cities and covering 25 countries over seven geographical regions of the world. Anomalies in the air pollutant concentrations (increases or decreases during 2020 periods compared to equivalent 2015–2019 periods) were calculated and the possible effects of meteorological conditions were analysed by computing anomalies from ERA5 reanalyses and local observations for these periods. We observed a positive correlation between the reductions in NO2 and NOx concentrations and peoples’ mobility for most cities. A correlation between PMC and mobility changes was also seen for some Asian and South American cities. A clear signal was not observed for other pollutants, suggesting that sources besides vehicular emissions also substantially contributed to the change in air quality. As a global and regional overview of the changes in ambient concentrations of key air quality species, we observed decreases of up to about 70% in mean NO2 and between 30% and 40% in mean PM2.5 concentrations over 2020 full lockdown compared to the same period in 2015–2019. However, PM2.5 exhibited complex signals, even within the same region, with increases in some Spanish cities, attributed mainly to the long-range transport of African dust and/or biomass burning (corroborated with the analysis of NO2/CO ratio). Some Chinese cities showed similar increases in PM2.5 during the lockdown periods, but in this case, it was likely due to secondary PM formation. Changes in O3 concentrations were highly heterogeneous, with no overall change or small increases (as in the case of Europe), and positive anomalies of 25% and 30% in East Asia and South America, respectively, with Colombia showing the largest positive anomaly of ~70%. The SO2 anomalies were negative for 2020 compared to 2015–2019 (between ~25 to 60%) for all regions. For CO, negative anomalies were observed for all regions with the largest decrease for South America of up to ~40%. The NO2/CO ratio indicated that specific sites (such as those in Spanish cities) were affected by biomass burning plumes, which outweighed the NO2 decrease due to the general reduction in mobility (ratio of ~60%). Analysis of the total oxidant (OX = NO2 + O3) showed that primary NO2 emissions at urban locations were greater than the O3 production, whereas at background sites, OX was mostly driven by the regional contributions rather than local NO2 and O3 concentrations. The present study clearly highlights the importance of meteorology and episodic contributions (e.g., from dust, domestic, agricultural biomass burning and crop fertilizing) when analysing air quality in and around cities even during large emissions reductions. There is still the need to better understand how the chemical responses of secondary pollutants to emission change under complex meteorological conditions, along with climate change and socio-economic drivers may affect future air quality. The implications for regional and global policies are also significant, as our study clearly indicates that PM2.5 concentrations would not likely meet the World Health Organization guidelines in many parts of the world, despite the drastic reductions in mobility. Consequently, revisions of air quality regulation (e.g., the Gothenburg Protocol) with more ambitious targets that are specific to the different regions of the world may well be required.Peer reviewedFinal Published versio
Correction to: Two years later: Is the SARS-CoV-2 pandemic still having an impact on emergency surgery? An international cross-sectional survey among WSES members
Background: The SARS-CoV-2 pandemic is still ongoing and a major challenge for health care services worldwide. In the first WSES COVID-19 emergency surgery survey, a strong negative impact on emergency surgery (ES) had been described already early in the pandemic situation. However, the knowledge is limited about current effects of the pandemic on patient flow through emergency rooms, daily routine and decision making in ES as well as their changes over time during the last two pandemic years. This second WSES COVID-19 emergency surgery survey investigates the impact of the SARS-CoV-2 pandemic on ES during the course of the pandemic.
Methods: A web survey had been distributed to medical specialists in ES during a four-week period from January 2022, investigating the impact of the pandemic on patients and septic diseases both requiring ES, structural problems due to the pandemic and time-to-intervention in ES routine.
Results: 367 collaborators from 59 countries responded to the survey. The majority indicated that the pandemic still significantly impacts on treatment and outcome of surgical emergency patients (83.1% and 78.5%, respectively). As reasons, the collaborators reported decreased case load in ES (44.7%), but patients presenting with more prolonged and severe diseases, especially concerning perforated appendicitis (62.1%) and diverticulitis (57.5%). Otherwise, approximately 50% of the participants still observe a delay in time-to-intervention in ES compared with the situation before the pandemic. Relevant causes leading to enlarged time-to-intervention in ES during the pandemic are persistent problems with in-hospital logistics, lacks in medical staff as well as operating room and intensive care capacities during the pandemic. This leads not only to the need for triage or transferring of ES patients to other hospitals, reported by 64.0% and 48.8% of the collaborators, respectively, but also to paradigm shifts in treatment modalities to non-operative approaches reported by 67.3% of the participants, especially in uncomplicated appendicitis, cholecystitis and multiple-recurrent diverticulitis.
Conclusions: The SARS-CoV-2 pandemic still significantly impacts on care and outcome of patients in ES. Well-known problems with in-hospital logistics are not sufficiently resolved by now; however, medical staff shortages and reduced capacities have been dramatically aggravated over last two pandemic years
A global observational analysis to understand changes in air quality during exceptionally low anthropogenic emission conditions
This global study, which has been coordinated by the World Meteorological Organization Global Atmospheric
Watch (WMO/GAW) programme, aims to understand the behaviour of key air pollutant species during the
COVID-19 pandemic period of exceptionally low emissions across the globe. We investigated the effects of the
differences in both emissions and regional and local meteorology in 2020 compared with the period 2015–2019.
By adopting a globally consistent approach, this comprehensive observational analysis focuses on changes in air
quality in and around cities across the globe for the following air pollutants PM2.5, PM10, PMC (coarse fraction of
PM), NO2, SO2, NOx, CO, O3 and the total gaseous oxidant (OX = NO2 + O3) during the pre-lockdown, partial
lockdown, full lockdown and two relaxation periods spanning from January to September 2020. The analysis is
based on in situ ground-based air quality observations at over 540 traffic, background and rural stations, from 63
cities and covering 25 countries over seven geographical regions of the world. Anomalies in the air pollutant
concentrations (increases or decreases during 2020 periods compared to equivalent 2015–2019 periods) were
calculated and the possible effects of meteorological conditions were analysed by computing anomalies from
ERA5 reanalyses and local observations for these periods. We observed a positive correlation between the reductions
in NO2 and NOx concentrations and peoples’ mobility for most cities. A correlation between PMC and
mobility changes was also seen for some Asian and South American cities. A clear signal was not observed for
other pollutants, suggesting that sources besides vehicular emissions also substantially contributed to the change
in air quality.
As a global and regional overview of the changes in ambient concentrations of key air quality species, we
observed decreases of up to about 70% in mean NO2 and between 30% and 40% in mean PM2.5 concentrations
over 2020 full lockdown compared to the same period in 2015–2019. However, PM2.5 exhibited complex signals,
even within the same region, with increases in some Spanish cities, attributed mainly to the long-range transport
of African dust and/or biomass burning (corroborated with the analysis of NO2/CO ratio). Some Chinese cities
showed similar increases in PM2.5 during the lockdown periods, but in this case, it was likely due to secondary
PM formation. Changes in O3 concentrations were highly heterogeneous, with no overall change or small increases
(as in the case of Europe), and positive anomalies of 25% and 30% in East Asia and South America,
respectively, with Colombia showing the largest positive anomaly of ~70%. The SO2 anomalies were negative for
2020 compared to 2015–2019 (between ~25 to 60%) for all regions. For CO, negative anomalies were observed for all regions with the largest decrease for South America of up to ~40%. The NO2/CO ratio indicated that
specific sites (such as those in Spanish cities) were affected by biomass burning plumes, which outweighed the
NO2 decrease due to the general reduction in mobility (ratio of ~60%). Analysis of the total oxidant (OX = NO2
+ O3) showed that primary NO2 emissions at urban locations were greater than the O3 production, whereas at
background sites, OX was mostly driven by the regional contributions rather than local NO2 and O3 concentrations.
The present study clearly highlights the importance of meteorology and episodic contributions (e.g.,
from dust, domestic, agricultural biomass burning and crop fertilizing) when analysing air quality in and around
cities even during large emissions reductions. There is still the need to better understand how the chemical
responses of secondary pollutants to emission change under complex meteorological conditions, along with
climate change and socio-economic drivers may affect future air quality. The implications for regional and global
policies are also significant, as our study clearly indicates that PM2.5 concentrations would not likely meet the
World Health Organization guidelines in many parts of the world, despite the drastic reductions in mobility.
Consequently, revisions of air quality regulation (e.g., the Gothenburg Protocol) with more ambitious targets that
are specific to the different regions of the world may well be required.World Meteorological Organization Global Atmospheric Watch
programme is gratefully acknowledged for initiating and coordinating
this study and for supporting this publication.
We acknowledge the following projects for supporting the analysis
contained in this article:
Air Pollution and Human Health for an Indian Megacity project
PROMOTE funded by UK NERC and the Indian MOES, Grant reference
number NE/P016391/1;
Regarding project funding from the European Commission, the sole
responsibility of this publication lies with the authors. The European
Commission is not responsible for any use that may be made of the information
contained therein.
This project has received funding from the European Commission’s
Horizon 2020 research and innovation program under grant agreement
No 874990 (EMERGE project).
European Regional Development Fund (project MOBTT42) under the
Mobilitas Pluss programme;
Estonian Research Council (project PRG714);
Estonian Research Infrastructures Roadmap project Estonian Environmental
Observatory (KKOBS, project 2014-2020.4.01.20-0281).
European network for observing our changing planet project (ERAPLANET,
grant agreement no. 689443) under the European Union’s
Horizon 2020 research and innovation program, Estonian Ministry of
Sciences projects (grant nos. P180021, P180274), and the Estonian
Research Infrastructures Roadmap project Estonian Environmental Observatory
(3.2.0304.11-0395).
Eastern Mediterranean and Middle East—Climate and Atmosphere Research (EMME-CARE) project, which has received funding from the
European Union’s Horizon 2020 Research and Innovation Programme
(grant agreement no. 856612) and the Government of Cyprus.
INAR acknowledges support by the Russian government (grant
number 14.W03.31.0002), the Ministry of Science and Higher Education
of the Russian Federation (agreement 14.W0331.0006), and the Russian
Ministry of Education and Science (14.W03.31.0008). We are grateful to to the following agencies for providing access to
data used in our analysis:
A.M. Obukhov Institute of Atmospheric Physics Russian Academy of
Sciences;
Agenzia Regionale per la Protezione dell’Ambiente della Campania
(ARPAC);
Air Quality and Climate Change, Parks and Environment (MetroVancouver,
Government of British Columbia);
Air Quality Monitoring & Reporting, Nova Scotia Environment
(Government of Nova Scotia);
Air Quality Monitoring Network (SIMAT) and Emission Inventory,
Mexico City Environment Secretariat (SEDEMA);
Airparif (owner & provider of the Paris air pollution data);
ARPA Lazio, Italy;
ARPA Lombardia, Italy;
Association Agr´e´ee de Surveillance de la Qualit´e de l’Air en ˆIle-de-
France AIRPARIF / Atmo-France;
Bavarian Environment Agency, Germany;
Berlin Senatsverwaltung für Umwelt, Verkehr und Klimaschutz,
Germany;
California Air Resources Board;
Central Pollution Control Board (CPCB), India;
CETESB: Companhia Ambiental do Estado de S˜ao Paulo, Brazil.
China National Environmental Monitoring Centre;
Chandigarh Pollution Control Committee (CPCC), India.
DCMR Rijnmond Environmental Service, the Netherlands.
Department of Labour Inspection, Cyprus;
Department of Natural Resources Management and Environmental
Protection of Moscow.
Environment and Climate Change Canada;
Environmental Monitoring and Science Division Alberta Environment
and Parks (Government of Alberta);
Environmental Protection Authority Victoria (Melbourne, Victoria,
Australia);
Estonian Environmental Research Centre (EERC);
Estonian University of Life Sciences, SMEAR Estonia;
European Regional Development Fund (project MOBTT42) under
the Mobilitas Pluss programme;
Finnish Meteorological Institute;
Helsinki Region Environmental Services Authority;
Haryana Pollution Control Board (HSPCB), IndiaLondon Air Quality
Network (LAQN) and the Automatic Urban and Rural Network (AURN)
supported by the Department of Environment, Food and Rural Affairs,
UK Government;
Madrid Municipality;
Met Office Integrated Data Archive System (MIDAS);
Meteorological Service of Canada;
Minist`ere de l’Environnement et de la Lutte contre les changements
climatiques (Gouvernement du Qu´ebec);
Ministry of Environment and Energy, Greece;
Ministry of the Environment (Chile) and National Weather Service
(DMC);
Moscow State Budgetary Environmental Institution
MOSECOMONITORING.
Municipal Department of the Environment SMAC, Brazil;
Municipality of Madrid public open data service;
National institute of environmental research, Korea;
National Meteorology and Hydrology Service (SENAMHI), Peru;
New York State Department of Environmental Conservation;
NSW Department of Planning, Industry and Environment;
Ontario Ministry of the Environment, Conservation and Parks,
Canada;
Public Health Service of Amsterdam (GGD), the Netherlands.
Punjab Pollution Control Board (PPCB), India.
R´eseau de surveillance de la qualit´e de l’air (RSQA) (Montr´eal);
Rosgydromet. Mosecomonitoring, Institute of Atmospheric Physics,
Russia;
Russian Foundation for Basic Research (project 20–05–00254)
SAFAR-IITM-MoES, India;
S˜ao Paulo State Environmental Protection Agency, CETESB;
Secretaria de Ambiente, DMQ, Ecuador;
Secretaría Distrital de Ambiente, Bogot´a, Colombia.
Secretaria Municipal de Meio Ambiente Rio de Janeiro;
Mexico City Atmospheric Monitoring System (SIMAT); Mexico City
Secretariat of Environment, Secretaría del Medio Ambiente (SEDEMA);
SLB-analys, Sweden;
SMEAR Estonia station and Estonian University of Life Sciences
(EULS);
SMEAR stations data and Finnish Center of Excellence;
South African Weather Service and Department of Environment,
Forestry and Fisheries through SAAQIS;
Spanish Ministry for the Ecological Transition and the Demographic
Challenge (MITECO);
University of Helsinki, Finland;
University of Tartu, Tahkuse air monitoring station;
Weather Station of the Institute of Astronomy, Geophysics and Atmospheric
Science of the University of S˜ao Paulo;
West Bengal Pollution Control Board (WBPCB).http://www.elsevier.com/locate/envintam2023Geography, Geoinformatics and Meteorolog
Deep Underground Neutrino Experiment (DUNE), Far Detector Technical Design Report, Volume I: Introduction to DUNE
The preponderance of matter over antimatter in the early universe, the dynamics of the supernovae that produced the heavy elements necessary for life, and whether protons eventually decay -- these mysteries at the forefront of particle physics and astrophysics are key to understanding the early evolution of our universe, its current state, and its eventual fate. The Deep Underground Neutrino Experiment (DUNE) is an international world-class experiment dedicated to addressing these questions as it searches for leptonic charge-parity symmetry violation, stands ready to capture supernova neutrino bursts, and seeks to observe nucleon decay as a signature of a grand unified theory underlying the standard model. The DUNE far detector technical design report (TDR) describes the DUNE physics program and the technical designs of the single- and dual-phase DUNE liquid argon TPC far detector modules. This TDR is intended to justify the technical choices for the far detector that flow down from the high-level physics goals through requirements at all levels of the Project. Volume I contains an executive summary that introduces the DUNE science program, the far detector and the strategy for its modular designs, and the organization and management of the Project. The remainder of Volume I provides more detail on the science program that drives the choice of detector technologies and on the technologies themselves. It also introduces the designs for the DUNE near detector and the DUNE computing model, for which DUNE is planning design reports. Volume II of this TDR describes DUNE's physics program in detail. Volume III describes the technical coordination required for the far detector design, construction, installation, and integration, and its organizational structure. Volume IV describes the single-phase far detector technology. A planned Volume V will describe the dual-phase technology
Deep Underground Neutrino Experiment (DUNE), Far Detector Technical Design Report, Volume II: DUNE Physics
The preponderance of matter over antimatter in the early universe, the dynamics of the supernovae that produced the heavy elements necessary for life, and whether protons eventually decay -- these mysteries at the forefront of particle physics and astrophysics are key to understanding the early evolution of our universe, its current state, and its eventual fate. DUNE is an international world-class experiment dedicated to addressing these questions as it searches for leptonic charge-parity symmetry violation, stands ready to capture supernova neutrino bursts, and seeks to observe nucleon decay as a signature of a grand unified theory underlying the standard model. The DUNE far detector technical design report (TDR) describes the DUNE physics program and the technical designs of the single- and dual-phase DUNE liquid argon TPC far detector modules. Volume II of this TDR, DUNE Physics, describes the array of identified scientific opportunities and key goals. Crucially, we also report our best current understanding of the capability of DUNE to realize these goals, along with the detailed arguments and investigations on which this understanding is based. This TDR volume documents the scientific basis underlying the conception and design of the LBNF/DUNE experimental configurations. As a result, the description of DUNE's experimental capabilities constitutes the bulk of the document. Key linkages between requirements for successful execution of the physics program and primary specifications of the experimental configurations are drawn and summarized. This document also serves a wider purpose as a statement on the scientific potential of DUNE as a central component within a global program of frontier theoretical and experimental particle physics research. Thus, the presentation also aims to serve as a resource for the particle physics community at large
Una Experiencia en el Cálculo de Áreas Usando Como Herramienta de Cómputo el Mathematica
ResumenEl presente artículo muestra una experiencia a cerca del cálculo de áreas bajo la curva de una función de una manera no rutinaria, haciendo uso del software Mathematica. La forma de realizar los cálculos implica el uso de determinantes para el cómputo de áreas de triángulos y la tecnología, lo que permitió llevar a cabo un proceso de exploración y experimentación, sin la consabida pérdida de tiempo que implican los tediosos y repetitivos cálculos, lo que fue conduciendo a interesantes hallazgos y a una forma diferente de encontrar áreas bajo la curva. Lo anterior, nos lleva a una revisión bibliográfica del uso de las nuevas tecnologías y al planteamiento de una línea de investigación.Palabras clave: Cálculo de áreas, curva de una función, software Mathematic
Una experiencia en el cálculo de áreas usando como herramienta de cómputo el Mathematica
El presente artículo muestra una experiencia a cerca del cálculo de áreas bajo la curva de una función de una manera no rutinaria, haciendo uso del software Mathematica. La forma de realizar los cálculos implica el uso de determinantes para el cómputo de áreas de triángulos y la tecnología, lo que permitió llevar a cabo un proceso de exploración y experimentación, sin la consabida pérdida de tiempo que implican los tediosos y repetitivos cálculos, lo que fue conduciendo a interesantes hallazgos y a una forma diferente de encontrar áreas bajo la curva. Lo anterior, nos lleva a una revisión bibliográfica del uso de las nuevas tecnologías y al planteamiento de una línea de investigación
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