3,025 research outputs found

    Systems thinking for sustainable textiles in the automotive sector.

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    According to Messe Frankfurt (2013), recycled and renewable raw materials are two main drivers in the growth of the Mobiletech markets which accounts for about 22% of the technical textiles base. However, the use of recycled textiles for consumer facing textiles within automobiles (such as car seat coverings or interior linings) appears to remain a complex issue; the core reason stated being the increased cost, even though the textiles are very similar to that produced from virgin polyester fibres. Studies have examined how sustainability has been incorporated into the automotive supply chain management at Volkswagen (Koplin et al.2007) and the optimization of the environmental compatibility of purchased goods such as ‘product-based green supply’ (Vermeulen et al. 2011), the importance of the consumer has also been acknowledged as a very influential driver to sustainable textile design (Diabat et al. 2014). This paper considers the progress that has been made to date in developing consumer facing sustainable textiles solutions for the automotive textiles sector. By examining the complexities regarding the design and use of sustainable textiles solutions such as recycled textiles or non-adhesive lamination within the automotive supply chain, we consider what needs to be done further to develop a sustainable approach to the automotive textile design system. Methods: The paper reviews the current state of sustainable textile solutions for the automotive sector, in particular the recycling of polyester to highlight how the processes of recycled polyester and sustainable textiles production are linked in the system of automotive sector. A case study with Sage AI (UK) outlines and examines their design, development and manufacture process for exterior textiles (ie for car seat coverings and interiors). Using content analysis of the interviews, company literature, textiles manufacturing literature and Integration Definition for Function Modelling, we created diagrams of the process which were validated by the Design Director at Sage AI UK. These diagrams and literature review are examined from a systems perspective to identify potential feedback loops and leverage points to effect change and how the process could divert waste from disposal. Results: The paper will present IDEFO diagrams of each stage of the design process, highlighting some of the issues regarding the process and a table outlining the decision making around the use of recycled textiles. The paper will also outline the system that textile design for the automotive sector operates within. The interviews found that, although Sage AI headquarters provide worldwide trends information to all Sage locations, the OEM’s concern regarding consumer knowledge within the EU markets; limited the greater use of recycled or non-adhesive laminated textiles the most sustainable textiles solutions, in favour of achieving lowest cost. Discussion: This study demonstrates how the design for automotive textiles is part of a system. Decisions around developing sustainable textiles solutions are through negotiation with the lead firm, the OEM that is seeking to manufacture the model. The automotive sector currently has governmental policy drivers for sustainability. Material stocks and flows and technology is also currently available for recyclable and sustainable textiles for the automotive sector. Although textiles recycling is an established practice and industry a number of issues are raised from this study that are common to areas such as fashion, home interiors and automotive. This need to be addressed such as marketing approaches for the recycled textiles, consumer knowledge about their uptake of recycled textiles, market development for recycled textiles products

    Proforma-based reporting in rectal cancer

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    The improvements in outcomes associate with the use of preoperative therapy rather than postoperative treatment means that clinical teams are increasingly reliant on imaging to identify high-risk features of disease to determine treatment plans. For many solid tumours, including rectal cancer, validated techniques have emerged in identifying prognostic factors pre-operatively. In the MERCURY study, a standardised scanning technique and the use of reporting proformas enabled consistently accurate assessment and documentation of the prognostic factors. This is now an essential tool to enable our clinical colleagues to make treatment decisions. In this review, we describe the proforma-based reporting tool that enables a systematic approach to the interpretation of the magnetic resonance images, thereby enabling all the clinically relevant features to be adequately assessed. © 2009 International Cancer Imaging Society

    Repeated sprints: an independent not dependent variable

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    The ability to repeatedly perform sprints has traditionally been viewed as a key performance measure in team sports, and the relationship between repeated-sprint ability (RSA) and performance has been explored extensively. However, when reviewing the repeated-sprint profile of team-sports match play it appears that the occurrence of repeated-sprint bouts is sparse, indicating that RSA is not as important to performance as commonly believed. Repeated sprints are, however, a potent and time-efficient training strategy, effective in developing acceleration, speed, explosive leg power, aerobic power, and high-intensity-running performance—all of which are crucial to team-sport performance. As such, we propose that repeated-sprint exercise in team sports should be viewed as an independent variable (eg, a means of developing fitness) as opposed to a dependent variable (eg, a means of assessing fitness/performance)

    Dynamic SU(2) Structure from Seven-branes

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    We obtain a family of supersymmetric solutions of type IIB supergravity with dynamic SU(2) structure, which describe the local geometry near a stack of four D7-branes and one O7-plane wrapping a rigid four-cycle. The deformation to a generalized complex geometry is interpreted as a consequence of nonperturbative effects in the seven-brane gauge theory. We formulate the problem for seven-branes wrapping the base of an appropriate del Pezzo cone, and in the near-stack limit in which the four-cycle is flat, we obtain an exact solution in closed form. Our solutions serve to characterize the local geometry of nonperturbatively-stabilized flux compactifications.Comment: 49 pages, 2 figures; v2: minor corrections, references adde

    Lack of effect of adenosine on the function of rodent osteoblasts and osteoclasts in vitro

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    Extracellular ATP, signalling through P2 receptors, exerts well-documented effects on bone cells, inhibiting mineral deposition by osteoblasts and stimulating the formation and resorptive activity of osteoclasts. The aims of this study were to determine the potential osteotropic effects of adenosine, the hydrolysis product of ATP, on primary bone cells in vitro. We determined the effect of exogenous adenosine on (1) the growth, alkaline phosphatase (TNAP) activity and bone-forming ability of osteoblasts derived from the calvariae of neonatal rats and mice and the marrow of juvenile rats and (2) the formation and resorptive activity of osteoclasts from juvenile mouse marrow. Reverse transcription polymerase chain reaction (RT-PCR) analysis showed marked differences in the expression of P1 receptors in osteoblasts from different sources. Whilst mRNA for the A1 and A2B receptors was expressed by all primary osteoblasts, A2A receptor expression was limited to rat bone marrow and mouse calvarial osteoblasts and the A3 receptor to rat bone marrow osteoblasts. We found that adenosine had no detectable effects on cell growth, TNAP activity or bone formation by rodent osteoblasts in vitro. The analogue 2-chloroadenosine, which is hydrolysed more slowly than adenosine, had no effects on rat or mouse calvarial osteoblasts but increased TNAP activity and bone formation by rat bone marrow osteoblasts by 30–50 % at a concentration of 1 μM. Osteoclasts were found to express the A2A, A2B and A3 receptors; however, neither adenosine (≤100 μM) nor 2-chloroadenosine (≤10 μM) had any effect on the formation or resorptive activity of mouse osteoclasts in vitro. These results suggest that adenosine, unlike ATP, is not a major signalling molecule in the bone

    A Cervid Vocal Fold Model Suggests Greater Glottal Efficiency in Calling at High Frequencies

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    Male Rocky Mountain elk (Cervus elaphus nelsoni) produce loud and high fundamental frequency bugles during the mating season, in contrast to the male European Red Deer (Cervus elaphus scoticus) who produces loud and low fundamental frequency roaring calls. A critical step in understanding vocal communication is to relate sound complexity to anatomy and physiology in a causal manner. Experimentation at the sound source, often difficult in vivo in mammals, is simulated here by a finite element model of the larynx and a wave propagation model of the vocal tract, both based on the morphology and biomechanics of the elk. The model can produce a wide range of fundamental frequencies. Low fundamental frequencies require low vocal fold strain, but large lung pressure and large glottal flow if sound intensity level is to exceed 70 dB at 10 m distance. A high-frequency bugle requires both large muscular effort (to strain the vocal ligament) and high lung pressure (to overcome phonation threshold pressure), but at least 10 dB more intensity level can be achieved. Glottal efficiency, the ration of radiated sound power to aerodynamic power at the glottis, is higher in elk, suggesting an advantage of high-pitched signaling. This advantage is based on two aspects; first, the lower airflow required for aerodynamic power and, second, an acoustic radiation advantage at higher frequencies. Both signal types are used by the respective males during the mating season and probably serve as honest signals. The two signal types relate differently to physical qualities of the sender. The low-frequency sound (Red Deer call) relates to overall body size via a strong relationship between acoustic parameters and the size of vocal organs and body size. The high-frequency bugle may signal muscular strength and endurance, via a ‘vocalizing at the edge’ mechanism, for which efficiency is critical

    Whole home exercise intervention for depression in older care home residents (the OPERA study) : a process evaluation

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    Background: The ‘Older People’s Exercise intervention in Residential and nursing Accommodation’ (OPERA) cluster randomised trial evaluated the impact of training for care home staff together with twice-weekly, physiotherapist-led exercise classes on depressive symptoms in care home residents, but found no effect. We report a process evaluation exploring potential explanations for the lack of effect. Methods: The OPERA trial included over 1,000 residents in 78 care homes in the UK. We used a mixed methods approach including quantitative data collected from all homes. In eight case study homes, we carried out repeated periods of observation and interviews with residents, care staff and managers. At the end of the intervention, we held focus groups with OPERA research staff. We reported our first findings before the trial outcome was known. Results: Homes showed large variations in activity at baseline and throughout the trial. Overall attendance rate at the group exercise sessions was low (50%). We considered two issues that might explain the negative outcome: whether the intervention changed the culture of the homes, and whether the residents engaged with the intervention. We found low levels of staff training, few home champions for the intervention and a culture that prioritised protecting residents from harm over encouraging activity. The trial team delivered 3,191 exercise groups but only 36% of participants attended at least 1 group per week and depressed residents attended significantly fewer groups than those who were not depressed. Residents were very frail and therefore most groups only included seated exercises. Conclusions: The intervention did not change the culture of the homes and, in the case study homes, activity levels did not change outside the exercise groups. Residents did not engage in the exercise groups at a sufficient level, and this was particularly true for those with depressive symptoms at baseline. The physical and mental frailty of care home residents may make it impossible to deliver a sufficiently intense exercise intervention to impact on depressive symptoms

    Do red deer stags (Cervus elaphus) use roar fundamental frequency (F0) to assess rivals?

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    It is well established that in humans, male voices are disproportionately lower pitched than female voices, and recent studies suggest that this dimorphism in fundamental frequency (F0) results from both intrasexual (male competition) and intersexual (female mate choice) selection for lower pitched voices in men. However, comparative investigations indicate that sexual dimorphism in F0 is not universal in terrestrial mammals. In the highly polygynous and sexually dimorphic Scottish red deer Cervus elaphus scoticus, more successful males give sexually-selected calls (roars) with higher minimum F0s, suggesting that high, rather than low F0s advertise quality in this subspecies. While playback experiments demonstrated that oestrous females prefer higher pitched roars, the potential role of roar F0 in male competition remains untested. Here we examined the response of rutting red deer stags to playbacks of re-synthesized male roars with different median F0s. Our results show that stags’ responses (latencies and durations of attention, vocal and approach responses) were not affected by the F0 of the roar. This suggests that intrasexual selection is unlikely to strongly influence the evolution of roar F0 in Scottish red deer stags, and illustrates how the F0 of terrestrial mammal vocal sexual signals may be subject to different selection pressures across species. Further investigations on species characterized by different F0 profiles are needed to provide a comparative background for evolutionary interpretations of sex differences in mammalian vocalizations

    Phases of one dimensional large N gauge theory in a 1/D expansion

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    We consider large N Yang Mills theory with D adjoint scalar fields in d dimensions for d=0 or 1. We show the existence of a non-trivial saddle point of the functional integral at large D which is characterized by a mass gap for the adjoint scalars. We integrate out the adjoint scalars in a 1/D expansion around the saddle point. In case of one dimension which is regarded as a circle, this procedure leads to an effective action for the Wilson line. We find an analogue of the confinement/deconfinement transition which consists of a second order phase transition from a uniform to a non-uniform eigenvalue distribution of the Wilson line, closely followed by a Gross-Witten-Wadia transition where a gap develops in the eigenvalue distribution. The phase transition can be regarded as a continuation of a Gregory-Laflamme transition. Our methods involve large values of the dimensionless 'tHooft coupling. The analysis in this paper is quantitatively supported by earlier numerical work for D=9.Comment: 27 pages + 21 pages of Appendix; 8 figures, v2:some comments are added in sec.4.3, minor corrections, one reference added, v3: minor corrections, one reference added, version to be published in JHE
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