616 research outputs found
Medición de usabilidad de trámites públicos en línea en Chile: un caso de estudio en gobierno electrónico
The possibility of conducting public online transactions means an important help to users and a reduction of governmental resources. However, the usage of the digital channel can get obstructed by different variables where the usability of the service plays an important role. This research presents a usability evaluation of 60 online services offered by the Chilean government. Following a heuristic evaluation model, we conducted a diagnosis and propose lines of improvement to the problems detected. The evaluation showed that the online services do not offer enough control to users, the services cause uncertainty while interacting with them, and there is not enough guidance to users during relevant steps of the interaction. The evaluation shows that usability is an important variable when explaining the difficulties of public online services spreading between users and it suggests that interventions in this sense could make more efficient the digital channel within the e-government context.La posibilidad de realizar cada vez más trámites públicos en línea (TPL) supone una vital ayuda a los usuarios y una disminución en los recursos que el gobierno debe invertir en acercarse a éstos. No obstante, el uso de herramientas digitales por parte de los usuarios parece dificultado por una serie de variables donde la usabilidad de los sistemas juega un rol preponderante. Esta investigación presenta una evaluación de la usabilidad de 60 TPLs en Chile a partir de la metodología de evaluación heurística, y propone mejoras a partir de un diagnóstico objetivo. Esta evaluación muestra 3 problemas principales en el servicio de TPLs en Chile: (1) los usuarios no sienten control en las acciones que realizan, (2) el sitio genera incertidumbre, (3) no se guía a los usuarios al realizar tareas relevantes. Ésto demuestra que la usabilidad es una variable importante al momento de explicar los problemas de masificación de los servicios en línea de gobierno electrónico, y que intervenciones en este sentido pueden hacerlos más eficientes tanto en Chile como otros países hispanoparlantes
Transcriptomic profiles and diagnostic biomarkers in the Mediterranean seagrasses Posidonia oceanica and Cymodocea nodosa reveal mechanistic insights of adaptative strategies upon desalination brine stress
Seawater desalination by reverse osmosis is growing exponentially due to water scarcity. Byproducts of this process (e.g. brines), are generally discharged directly into the coastal ecosystem, causing detrimental effects, on benthic organisms. Understanding the cellular stress response of these organisms (biomarkers), could be crucial for establishing appropriate salinity thresholds for discharged brines. Early stress biomarkers can serve as valuable tools for monitoring the health status of brine-impacted organisms, enabling the prediction of long-term irreversible damage caused by the desalination industry. In this study, we conducted laboratory-controlled experiments to assess cellular and molecular biomarkers against brine exposure in two salinity-sensitive Mediterranean seagrasses: Posidonia oceanica and Cymodocea nodosa. Treatments involved exposure to 39, 41, and 43 psu, for 6 h and 7 days. Results indicated that photosynthetic performance remained unaffected across all treatments. However, under 43 psu, P. oceanica and C. nodosa exhibited lipid oxidative damage, which occurred earlier in P. oceanica. Additionally, P. oceanica displayed an antioxidant response at higher salinities by accumulating phenolic compounds within 6 h and ascorbate within 7 d; whereas for C. nodosa the predominant antioxidant mechanisms were phenolic compounds accumulation and total radical scavenging activity, which was evident after 7 d of brines exposure. Finally, transcriptomic analyses in P. oceanica exposed to 43 psu for 7 days revealed a poor up-regulation of genes associated with brassinosteroid response and abiotic stress response, while a high down-regulation of genes related to primary metabolism was detected. In C. nodosa, up-regulated genes were involved in DNA repair, cell cycle regulation, and reproduction, while down-regulated genes were mainly associated with photosynthesis and ribosome assembly. Overall, these findings suggest that 43 psu is a critical salinity-damage threshold for both seagrasses; and despite the moderate overexpression of several transcripts that could confer salt tolerance, genes involved in essential biological processes were severely downregulated.FRR was financed by Fondecyt #11220425 grant from ANID, Chile. CAS was financed by project ANID InES I + D 2021 (INID210013) and by Marie Skłodowska-Curie Action (888415). FBM was supported by a grant from Universidad de Alicante (Grant ID: FPUUA98)
What Is the Support for Conspiracy Beliefs About COVID-19 Vaccines in Latin America? A Prospective Exploratory Study in 13 Countries
Conspiracy theories about COVID-19 began to emerge immediately after the first news about the disease and threaten to prolong the negative impact of the COVID-19 pandemic by limiting people’s willingness of receiving a life-saving vaccine. In this context, this study aimed to explore the variation of conspiracy beliefs regarding COVID-19 and the vaccine against it in 5779 people living in 13 Latin American countries (Argentina, Bolivia, Chile, Colombia, Cuba, Ecuador, El Salvador, Guatemala, Mexico, Paraguay, Peru, Uruguay and Venezuela) according to sociodemographic variables such as gender, age, educational level and source of information about COVID-19. The study was conducted during the COVID-19 pandemic between September 15 and October 25, 2021. The Spanish-language COVID-19 Vaccine Conspiracy Beliefs Scale (ECCV-COVID) and a sociodemographic survey were used. The results indicate that, in most countries, women, people with a lower educational level and those who receive information about the vaccine and COVID-19 from family/friends are more supportive of conspiracy ideas regarding the COVID-19 vaccine. In the case of age, the results vary by country. The analysis of the responses to each of the questions of the ECCV-COVID reveals that, in general, the countries evaluated are mostly in some degree of disagreement or indecision regarding conspiratorial beliefs about COVID-19 vaccines. The findings could help open further study which could support prevention and treatment efforts during the COVID-19 pandemic
Design and Cross-Cultural Invariance of the COVID-19 Vaccine Conspiracy Beliefs Scale (COVID-VCBS) in 13 Latin American Countries
"Aims: Over the past 2 years, the vaccine conspiracy beliefs construct has been used in
a number of different studies. These publications have assessed the determinants and
outcomes of vaccine conspiracy beliefs using, in some cases, pooled data from different
countries, and compared the results across these contexts. However, studies often
do not consider measurement invariance as a necessary requirement for comparative
analyses. Therefore, the aim of this study was to develop and evaluate the crosscultural MI of the COVID-19 Vaccine Conspiracy Beliefs Scale (COVID-VCBS) in 12 Latin
American countries.
Methods: Confirmatory factor analysis, item response theory analysis and alignment
method were applied to test measurement invariance in a large number of groups. Results: The COVID-VCBS showed robust psychometric properties and measurement
invariance for both factor loadings and crosstabs. Also, a higher level of acceptance of
conspiracy beliefs about vaccines is necessary to respond to higher response categories.
Similarly, greater acceptance of conspiracy beliefs about COVID-19 vaccines was related
to a lower intention to be vaccinated.
Conclusion: The results allow for improved understanding of conspiracy beliefs about
COVID-19 vaccines in the countries assessed; furthermore, they provide researchers
and practitioners with an invariant measure that they can use in cross-cultural studies in
Latin America. However, further studies are needed to test invariance in other countries,
with the goal of developing a truly international measure of conspiracy beliefs about
COVID-19 vaccines.
Network analysis of the relationships between conspiracy beliefs towards COVID-19 vaccine and symptoms of fear of COVID-19 in a sample of latin american countries
The present study examined how conspiracy beliefs about COVID-19 vaccines specifically relate to symptoms of fear of COVID-19 in a sample of four South American countries. A total of 1785 people from Bolivia, Colombia, Ecuador, and Peru participated, responding to a sociodemographic survey, the Fear of COVID-19 scale (FCV-19 S) and the Vaccine Conspiracy Beliefs Scale-COVID-19 (VCBS-COVID-19). Network analysis identified the most important symptoms of fear and conspiracy beliefs about COVID-19 vaccines (nodes) and the associations between them (edges). In addition, the robustness of the network of these indicators of centrality and the possible differences in the structure and connectivity of the networks between the four countries were evaluated. The results suggest that the nodes with the highest centrality were items 2 and 5 of the FCV-19 S and item 2 of the VCBS-COVID-19. Likewise, item 6 is the belief that most predicts conspiracy beliefs about vaccines against COVID-19; while item 6 was the symptom that most predicts fear of COVID-19. The findings strongly support cross-cultural similarities in the networks across the four countries rather than differences. Although it was expected that a higher presence of symptoms of fear of COVID-19 may lead people to compensate for their fear by believing in conspiratorial ideas about vaccines and, consequently, rejecting the COVID-19 vaccine, the results do not clearly show this relationship. This could lead other researchers to generate evidence to explain the differences between Latin American countries and countries in other contexts in terms of vaccination rates. This evidence could be useful to develop policies favoring vaccination against COVID-19 that are more contextualized to the Latin American region, characterized by social instability and economic recession during the pandemic
Cross-cultural validation of the new version of the Coronavirus Anxiety Scale in twelve Latin American countries
The Coronavirus Anxiety Scale (CAS) was recently developed to assess dysfunctional anxiety related to COVID-19. Although different studies reported that the CAS is psychometrically sound, it is unclear whether it is invariant across countries. Therefore, the present study aimed to examine the measurement invariance of the CAS in twelve Latin American countries (Argentina, Bolivia, Chile, Colombia, Cuba, Ecuador, El Salvador, Guatemala, Mexico, Paraguay, Peru, and Uruguay). A total of 5196 people participated, with a mean age of 34.06 (SD = 26.54). Multigroup confirmatory factor analysis (CFA) was used to examine the measurement invariance of the CAS across countries and gender. Additionally, the graded response model (GRM) was used to provide a global representation of the representativeness of the scale with respect to the COVID19 dysfunctional anxiety construct. The unidimensional structure of the five-item CAS was not confirmed in all countries. Therefore, it was suggested that a four-item model of the CAS (CAS-4) provides a better fit across the twelve countries and reliable scores. Multigroup CFA showed that the CAS-4 exhibits scalar invariance across all twelve countries and all genders. In addition, the CAS-4 items are more informative at average and high levels of COVID-19 dysfunctional anxiety than at lower levels. According to the results, the CAS-4 is an instrument with strong cross-cultural validity and is suitable for cross-cultural comparisons of COVID-19 dysfunctional anxiety symptoms in the general population of the twelve Latin American countries evaluated
Network analysis of the relationships between conspiracy beliefs towards COVID-19 vaccine and symptoms of fear of COVID-19 in a sample of latin american countries
"The present study examined how conspiracy beliefs about COVID-19 vaccines specifcally relate to symptoms of fear of
COVID-19 in a sample of four South American countries. A total of 1785 people from Bolivia, Colombia, Ecuador, and
Peru participated, responding to a sociodemographic survey, the Fear of COVID-19 scale (FCV-19 S) and the Vaccine
Conspiracy Beliefs Scale-COVID-19 (VCBS-COVID-19). Network analysis identifed the most important symptoms of
fear and conspiracy beliefs about COVID-19 vaccines (nodes) and the associations between them (edges). In addition, the
robustness of the network of these indicators of centrality and the possible diferences in the structure and connectivity
of the networks between the four countries were evaluated. The results suggest that the nodes with the highest centrality
were items 2 and 5 of the FCV-19 S and item 2 of the VCBS-COVID-19. Likewise, item 6 is the belief that most predicts
conspiracy beliefs about vaccines against COVID-19; while item 6 was the symptom that most predicts fear of COVID-19.
The fndings strongly support cross-cultural similarities in the networks across the four countries rather than diferences.
Although it was expected that a higher presence of symptoms of fear of COVID-19 may lead people to compensate for
their fear by believing in conspiratorial ideas about vaccines and, consequently, rejecting the COVID-19 vaccine, the
results do not clearly show this relationship. This could lead other researchers to generate evidence to explain the diferences between Latin American countries and countries in other contexts in terms of vaccination rates. This evidence could
be useful to develop policies favoring vaccination against COVID-19 that are more contextualized to the Latin American
region, characterized by social instability and economic recession during the pandemic.
COVID-19 anxiety, psychological well-being and preventive behaviors during the COVID-19 pandemic in Latin America and the Caribbean: relationships and explanatory model
This study assesses the relationship between COVID-19 anxiety and subjective well-being in terms of the mediating role of COVID-19 preventive behaviors. Additionally, the contribution of sociodemographic factors (sex and age) and risk perception on COVID-19 anxiety and its potential measurement invariance was tested in 5655 participants from 12 countries in Latin America and the Caribbean. A mixture of both latent and observable variables were analyzed using a system of structural equations. The Coronavirus Anxiety Scale (CAS), Preventive COVID-19 Infection Behaviors Scale (PCIBS) and single-item measures were used to assess the perceived probability of death, perceived severity and concern about transmitting COVID-19. The results indicated that there is a significant and relevant direct effect of COVID-19 anxiety on participants' well-being. Furthermore, COVID-19 anxiety significantly predicted both preventive behavior (β =.29, p <.01) and well-being (β = –.32, p <.01). The effects of COVID anxiety and preventive behavior explained 9.8% of the variance in well-being (R-square =.098); whereas, 8.4% of the variance in preventive behavior was associated with COVID anxiety (R-square =.084). Likewise, perceived likelihood of death from COVID, perceived severity of COVID, and concerns about COVID transmission were positively related to anxiety. Age was negatively related to anxiety, with men being less anxious than women. The results are invariant by country, i.e., the broad relationships found in the combined sample are also present in each individual country. The findings indicate that, although the exact relationships between variables may vary between countries, there are enough similarities to provide useful information about the impact of the COVID-19 pandemic in each of the countries included in the study
Giant tortoise genomes provide insights into longevity and age-related disease
© 2018, The Author(s), under exclusive licence to Springer Nature Limited. Giant tortoises are among the longest-lived vertebrate animals and, as such, provide an excellent model to study traits like longevity and age-related diseases. However, genomic and molecular evolutionary information on giant tortoises is scarce. Here, we describe a global analysis of the genomes of Lonesome George—the iconic last member of Chelonoidis abingdonii—and the Aldabra giant tortoise (Aldabrachelys gigantea). Comparison of these genomes with those of related species, using both unsupervised and supervised analyses, led us to detect lineage-specific variants affecting DNA repair genes, inflammatory mediators and genes related to cancer development. Our study also hints at specific evolutionary strategies linked to increased lifespan, and expands our understanding of the genomic determinants of ageing. These new genome sequences also provide important resources to help the efforts for restoration of giant tortoise populations
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