Three Moving Groups Detected in the LAMOST DR1 Archive

We analyze the kinematics of thick disk and halo stars observed by the Large sky Area Multi-Object Fiber Spectroscopic Telescope. We have constructed a sample of 7,993 F, G and K nearby main-sequence stars (\textit{d} $<$ 2 kpc) with estimates of position (x, y, z) and space velocity ($U$, $V$, $W$) based on color and proper motion from the SDSS DR9 catalog. Three `phase-space overdensities' are identified in [\textit{V}, $\sqrt{U^{2}+2V^{2}}$] with significance levels of $\sigma$ $>$ 3. %[L$_{Z}$, eccentricity], [L$_{Z}$, L$_{\bot}$], and [V$_{az}$, V$_{\triangle}E$]. Two of them (Hyades-Pleiades stream, Arcturus-AF06 stream) have been identified previously. We also find evidence for a new stream (centered at \textit{V} $\sim$ -180 km s$^{-1}$) in the halo. The formation mechanisms of these three streams are analyzed. Our results support the hypothesis the Arcturus-AF06 stream and the new stream originated from the debris of a disrupted satellite, while Hyades-Pleiades stream has a dynamical origin.Comment: 7 pages, 5 figure

Highly efficient preparation of Ce0.8Sm0.2O2-δ–SrCo0.9Nb0.1O3-δ dual-phase four-channel hollow fiber membrane via one-step thermal processing approach

Fabricating dual-phase hollow-fiber membranes via a one-step thermal processing (OSTP) approach is challenging, because of complex sintering kinetics and the subsequent impacts on membrane morphology, phase stability, and permeation properties. In this study, we have demonstrated that Ce0.8Sm0.2O2-δ-SrCo0.9Nb0.1O3-δ (SDC-SCN) four-channel hollow fiber membrane can be manufactured via a single high-temperature sintering process, by using metal oxides and carbonates directly as membrane materials (sources of metal ions). It has been found that use of a low ramping rate reduces grain sizes, increases grain and forming cobalt oxide nanoparticles, a key step to promoting surface exchange process followed by enhancing oxygen permeation. While the grain boundary interface region can be limited to approximately 20–30 nm. At 1173 K oxygen permeation of the SDC-SCN four-channel hollow fiber membrane was measured at approximately 1.2 mL cm−2·min−1 using helium as the sweep gas. Meanwhile, the dual-phase membrane shows a good tolerance to carbon dioxide, with the oxygen permeation flux fully recovered after long-term exposure to carbon dioxide (more than 100 h). This will enable further application of the OSTP approach for preparing dual-phase multi-channel hollow fiber membranes for applications of oxyfuel combustion, catalytic membrane reactors and carbon dioxide capture

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp3 papain-like protease

The COVID-19 pandemic has emerged as the biggest life-threatening disease of this century. Whilst vaccination should provide a long-term solution, this is pitted against the constant threat of mutations in the virus rendering the current vaccines less effective. Consequently, small molecule antiviral agents would be extremely useful to complement the vaccination program. The causative agent of COVID-19 is a novel coronavirus, SARS-CoV-2, which encodes at least nine enzymatic activities that all have drug targeting potential. The papain-like protease (PLpro) contained in the nsp3 protein generates viral non-structural proteins from a polyprotein precursor, and cleaves ubiquitin and ISG protein conjugates. Here we describe the expression and purification of PLpro. We developed a protease assay that was used to screen a custom compound library from which we identified dihydrotanshinone I and Ro 08-2750 as compounds that inhibit PLpro in protease and isopeptidase assays and also inhibit viral replication in cell culture-based assays

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

Self-etched bimetallic hybrid derived cobalt/zinc dual-sites coordinated N, P-codoped hollow carbon polyhedron for efficient oxygen reduction reaction

Hollow structure with hierarchical pore is benefit for the exposure of active sites, showing great advantages in electrocatalysis. Whereas, it still a challenge for the target preparation of such architecture in a simple, but efficient ways. Herein, a Co/Zn-Nx (Nx represents the number of N atoms (x) coordinated with Co or Zn atoms) dual sites anchored N, P-codoped hollow carbon polyhedron (PZH-800) with well-defined Co species was facilely prepared via direct pyrolysis of a bimetallic hybrid (PZH) obtained by polymerization-coating of Zn-porphyrin polymer on the surface of zeolitic-imidazolate-framework (ZIF-67). The hollow architecture was formed via self-etching, in which the hydrochloric acid produced during the formation of hybrid etched the inner acid-degradable ZIF-67. Different with post-etching method, self-etching could really preserve the original structure and catalytic sites, better regulate the electronic structures, enhancing the catalytic activity. Compared with the Co or Zn mono-doped sample, PZH-800 presented an enhanced ORR activity with a half-wave potential (E1/2) of 0.94 V (vs. RHE), as well as outstanding stability, outperforming commercial Pt/C (20%) in alkaline media. Impressively, ZABs using PZH-800 as the cathodic catalyst demonstrated a maximum power density (280 mW cm−2), coupled with a remarkable running stability, surpassing the battery catalyzed by Pt/C. This work paves a new avenue for the future development of MOF-derived non-precious metal-based hollow catalysts

Cr-Doped Pd Metallene Endows a Practical Formaldehyde Sensor New Limit and High Selectivity

Electrochemical sensors for detecting micromolecule organics are desirable for improving the perception of environmental quality and human health. However, currently, the electrochemical sensors for formaldehyde are substantially limited on the market due to the long-term unsolved problems of the low electrooxidation efficiency and CO poisoning issue of commercial Pd catalysts. Here, a 2D Cr-doped Pd metallene (Cr-Pdene) with few atomic layers is shown as an advanced catalyst for ultrasensitive and selective sensing of formaldehyde via a highly efficient formaldehyde electrooxidation. It is found that the doping of Cr into Pd metallene can efficiently optimize the electronic structure of Pd and weaken the interaction between Pd and CO, providing an anti-poisoning means to favor CO2 production and suppress CO adsorption. The Cr-Pdene-based electrochemical sensor exhibits one order of magnitude higher detection range and, especially, much higher anti-interference for formaldehyde than that of the conventional sensors. Most importantly, it is demonstrated that the Cr-Pdene can be integrated into commercializable wireless sensor networks or handheld instruments for promising applications relating to the environment, health, and food

Electropolymerized poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) film on ITO glass and its application in photovoltaic device

Poly(3,4-ethylenedioxythiopliene):poly(styrene sulfonate) (PEDOT:PSS) films have been electrochemically polymerized in situ on ITO glass substrate in boron trifluoride diethyl etherate electrolyte (BFEE). Cyclic voltammograms show good redox activity and stability of the PEDOT films. These films had been directly used to fabricate organic-inorganic hybrid solar cells with the structure of ITO/PEDOT/ZnO:MDMC-PPV/Al. The solar cells made of electrochemically polymerized films exhibit higher energy conversion efficiencies compared with that prepared by the spin-coating method, and the highest value is 0.33%. This in-situ electropolymerized method effectively simplifies fabricating procedures and may blaze a facile and economical route for producing high-efficiency solar cells