Overlapping modularity at the critical point of k-clique percolation

One of the most remarkable social phenomena is the formation of communities in social networks corresponding to families, friendship circles, work teams, etc. Since people usually belong to several different communities at the same time, the induced overlaps result in an extremely complicated web of the communities themselves. Thus, uncovering the intricate community structure of social networks is a non-trivial task with great potential for practical applications, gaining a notable interest in the recent years. The Clique Percolation Method (CPM) is one of the earliest overlapping community finding methods, which was already used in the analysis of several different social networks. In this approach the communities correspond to k-clique percolation clusters, and the general heuristic for setting the parameters of the method is to tune the system just below the critical point of k-clique percolation. However, this rule is based on simple physical principles and its validity was never subject to quantitative analysis. Here we examine the quality of the partitioning in the vicinity of the critical point using recently introduced overlapping modularity measures. According to our results on real social- and other networks, the overlapping modularities show a maximum close to the critical point, justifying the original criteria for the optimal parameter settings.Comment: 20 pages, 6 figure

Universal Arduino-based experimenting system to support teaching of natural sciences

The rapid evolution of intelligent electronic devices makes information technology, computer science and electronics strongly related to the teaching of natural sciences. Today almost everybody has a smart phone that can convert light, temperature, movement, sound to numbers, therefore all these can be processed, analysed, displayed, stored, shared by software applications. The fundamental question is how education can follow this knowledge and how can education take its advantages. Components and methods of modern technology are available for education also, teachers and students can play with parts and tools which were previously used only by engineers. A good example is the very popular Arduino board which is practically an industrial microcontroller whose pins are wired to easy-to-use connectors on a printed circuit board. In this paper we show a universal system which we have developed for the Arduino platform to support experimenting and understanding of the most fundamental principles of the operation of modern devices. We show our related educational concept and discuss the most important features of the system. Open source hardware and software are available and we provide a number of video tutorials as well

Land Quality and Landscape Processes

This monograph contains a selection of scientific papers presented on the conference on Land Quality and Landscape Processes, hold in Keszthely, Hungary. It covers topics related to various aspects of land quality including : concepts of assessment; evaluation of biomass productivity ; bioindicators of land quality ; quality assessment of degraded land ; land use related data processingJRC.H.5-Land Resources Managemen

Statistical Power Law due to Reservoir Fluctuations and the Universal Thermostat Independence Principle

Certain fluctuations in particle number at fixed total energy lead exactly to a cut-power law distribution in the one-particle energy, via the induced fluctuations in the phase-space volume ratio. The temperature parameter is expressed automatically by an equipartition relation, while the q-parameter is related to the scaled variance and to the expectation value of the particle number. For the binomial distribution q is smaller, for the negative binomial q is larger than one. These results also represent an approximation for general particle number distributions in the reservoir up to second order in the canonical expansion. For general systems the average phase-space volume ratio expanded to second order delivers a q parameter related to the heat capacity and to the variance of the temperature. However, q differing from one leads to non-additivity of the Boltzmann-Gibbs entropy. We demonstrate that a deformed entropy, K(S), can be constructed and used for demanding additivity. This requirement leads to a second order differential equation for K(S). Finally, the generalized q-entropy formula contains the Tsallis, Renyi and Boltzmann-Gibbs-Shannon expressions as particular cases. For diverging temperature variance we obtain a novel entropy formula.Comment: Talk given by T.S.Biro at Sigma Phi 2014, Rhodos, Greec

An Incremental OCL Compiler for Modeling Environments

In software engineering, reliability and development time are two of the most important aspects, therefore, modeling environments, which aide both, are widely used during software development. UML and OCL became industry standards, and are supported by many CASE tools. OCL code checking, which has to be performed by these tools, has a specialty, as not all of the information necessary for compilation is available from the code, the related model contains the types, navigations and attributes. The build time of OCL code fragments is increased if the development tool supports distributed modeling, because in this case, model element checking has to be performed in a model repository that cannot be held in memory. In this paper, we introduce a method that enables incremental OCL code building and therefore reduces the development time. Incremental builds require higher complexity than simple builds, thus balancing between the two methods is also considered

Pion Production Via Resonance Decay in a Non-extensive Quark-Gluon Medium with Non-additive Energy Composition Rule

Resonance production and decay into pion pairs is simulated in a non-extensive quark matter with multi-particle interactions. Final state pion spectra are found to take the form of the Tsallis distribution, in accordance with measurements. It has also been shown that, if a large number of particles with these multi-particle interactions are constrained to a constant energy hyper-surface in phase space, the one-particle distribution is the Tsallis distribution

An intelligent partner system for improving chronic illness care

Chronic care consists of a sequence of actions to treat a specific clinical disorder over time as a function of the ways in which illness progresses and patients respond to management actions. Outcomes depend on physicians' skills to select the actions best suited for their patients and competent self-management. This paper presents the architecture of an intelligent partner system (IPS), which helps to provide doctors with relevant data and skills and empowers chronically ill patients with the information and confidence to manage their health wisely. The services of this intelligent system are presented as 'therapies' for the information-processing 'pathologies' associated with traditional chronic illness care

Staurosporine induces necroptotic cell death under caspase-compromised conditions in U937 cells

For a long time necrosis was thought to be an uncontrolled process but evidences recently have revealed that necrosis can also occur in a regulated manner. Necroptosis, a type of programmed necrosis is defined as a death receptor-initiated process under caspase-compromised conditions. The process requires the kinase activity of receptor-interacting protein kinase 1 and 3 (RIPK1 and RIPK3) and mixed lineage kinase domain-like protein (MLKL), as a substrate of RIPK3. The further downstream events remain elusive. We applied known inhibitors to characterize the contributing enzymes in necroptosis and their effect on cell viability and different cellular functions were detected mainly by flow cytometry. Here we report that staurosporine, the classical inducer of intrinsic apoptotic pathway can induce necroptosis under caspase-compromised conditions in U937 cell line. This process could be hampered at least partially by the RIPK1 inhibitor necrotstin-1 and by the heat shock protein 90 kDa inhibitor geldanamycin. Moreover both the staurosporine-triggered and the classical death ligand-induced necroptotic pathway can be effectively arrested by a lysosomal enzyme inhibitor CA-074-OMe and the recently discovered MLKL inhibitor necrosulfonamide. We also confirmed that the enzymatic role of poly(ADP-ribose)polymerase (PARP) is dispensable in necroptosis but it contributes to membrane disruption in secondary necrosis. In conclusion, we identified a novel way of necroptosis induction that can facilitate our understanding of the molecular mechanisms of necroptosis. Our results shed light on alternative application of staurosporine, as a possible anticancer therapeutic agent. Furthermore, we showed that the CA-074-OMe has a target in the signaling pathway leading to necroptosis. Finally, we could differentiate necroptotic and secondary necrotic processes based on participation of PARP enzyme