47 research outputs found
A comparative analysis of gamma and hadron families at the superhigh energies recorded in experiment Pamir
A comparative analysis of hadron and gamma families which have undergone the decascading procedure is made. Results are compared with different models of interactions. In hadron families with energies Summary E sub H sup gamma 20 TeV as well as in gamma families with energies Summary E sub gamma 70 TeV, increasing azimuthal anisotropy is observed
Nuclear Interactions Of Super High Energy Cosmic-rays Observed In Mountain Emulsion Chambers
Here we present a summary of joint discussions on the results of three mountain experiments with large-scale emulsion chambers, at Pamir, Mt. Fuji and Chacaltaya. Observations cover gamma quanta, hadrons and their clusters (called "families"). The following topics are covered, concerning the characteristics of nuclear interactions the energy region 1014-1016 eV: (i) rapid dissipation seen in atmospheric diffusion of high-energy cosmic-rays; (ii) multiplicity and Pt increase in produced pi-mesons in the fragmentation region; (iii) existence of large-Pt jets, (iv) extremely hadron-rich family of the Centauro type; (v) exotic phenomena in the extremely high energy region beyond 1016 eV. Β© 1981.1911125(1977) Acta Univ. Lodz ser. II, (60)(1973) 13th Int. Cosmic-ray Conf., 3, p. 2228(1975) 14th Int. Cosmic-Ray Conf., 7, p. 2365(1979) AIP Conf. Proc. no. 49, p. 334(1979) 16th Int. Cosmic-ray Conf., 6, p. 344(1979) 16th Int. Cosmic-ray Conf., 7, p. 6816th Int. Cosmic-ray Conf. (1979) 16th Int. Cosmic-ray Conf., 7, p. 284(1979) 16th Int. Cosmic-ray Conf., 7, p. 294(1979) 16th Int. Cosmic-ray Conf., 13, p. 87(1979) 16th Int. Cosmic-ray Conf., 13, p. 92(1979) 16th Int. Cosmic-ray Conf., 13, p. 98(1979) AIP Conf. Proc. no. 49, p. 94(1979) AIP Conf. Proc. no. 49, p. 145(1979) AIP Conf. Proc. no. 49, p. 317(1979) 16th Int. Cosmic-ray Conf., 6, p. 350(1979) 16th Int. Cosmic-ray Conf., 6, p. 356(1979) 16th Int. Cosmic-ray Conf., 6, p. 362Nikolsky, Proc. 9th Int. High-energy Symp. (1978) CSSR, 21. , ToborMiyake, (1978) Proc. 19th Int. Conf. on High-energy physics, p. 433Vernov, (1977) Physica, 3, p. 1601Khristiansen, (1978) JETP Lett., 28, p. 124(1973) 13th Int. Cosmic-ray Conf., 3, p. 2219Izv. Acad. Nauk USSR, ser Phys. (1974) Izv. Acad. Nauk USSR, ser Phys., 38, p. 918(1975) 14th Int. Cosmic-ray Conf., 7, p. 2365(1979) 16th Int. Cosmic-ray Conf., 7, p. 68Dunaevsky, Urysson, Emelyanov, Shorin, Tashimov, (1975) FIAN preprint no. 150Dunaevsky, Urysson, Emelyanov, Shorin, Tashinov, (1979) Acta Univ. Lodz ser. II, (60), p. 199Ivanenko, Kanevskya, Roganova, (1978) JETP Lett., 40, p. 704Ivanenko, Kanevsky, Roganova, (1979) 16th Int. Cosmic-ray Conf., 7, p. 101Ivanenko, Kanevsky, Roganova, (1979) 16th Int. Cosmic-ray Conf., 7, p. 198Wrotniak, (1977) Acta Univ. Lodz ser. II, (60), p. 165Krys, Tomaszevski, Wrotniak, (1979) 16th Int. Cosmic-ray Conf., 7, p. 182Krys, Tomaszevski, Wrotniak, (1979) 16th Int. Cosmic-ray Conf., 7, p. 186Fomin, Kempa, Khristiansen, Levina, Piotrowska, Wdowczyk, (1977) 15th Int. Cosmic-ray Conf., 7, p. 248Fomin, Kempa, Khristiansen, Levina, Piotrowska, Wdowczyk, (1979) 16th Int. Cosmic-ray Conf., 13, p. 82Azimov, Mullazhanov, Yuldashbayev, (1979) 16th Int. Cosmic-ray Conf., 7, p. 262Azimov, Mullazhanov, Yuldashbayev, (1977) Acta Univ. Lodz ser. II, (60), p. 275Kasahara, Torri, Yuda, (1979) 16th Int. Cosmic-ray Conf., 13, p. 70Kasahara, Torii, Yuda, (1979) 16th Int. Cosmic-ray Conf., 13, p. 79Shibata, (1979) 16th Int. Cosmic-ray Conf., 7, p. 176H. Semba, T. Shibata and T. Tabuki, Suppl. Prog. Theor. Phys., to be publishedZhdanov, Roinishvilli, Smorodin, Tomaszevski, (1975) FIAN preprint no. 163Lattes, Fujimoto, Hasegawa, Hadronic interactions of high energy cosmic-ray observed by emulsion chambers (1980) Physics Reports, 65, p. 152Ellsworth, Gaisser, Yodh, (1981) Phys. Rev., 23 D, p. 764Baradzei, Smorodin, (1974) FIAN preprint nos. 103, 104Baradzei, Smorodin, (1977) Acta Univ. Lodz ser. II, (60), p. 51Zhdanov, (1980) FIAN preprint no. 140H. Semba, T. Shibata and T. Tabuki, Suppl. Prog. Theor. Phys., to be publishedShibata, (1980) Phys. Rev., 22 D, p. 100Slavatinsky, (1980) Proc. 7th European Symp. on Cosmic rays, , Leningrad, to be published(1979) AIP Conference Proc. no. 49, p. 145Azimov, Abduzhamilov, Chudakov, (1963) JETP (Sov. Phys.), 45, p. 40713th Int. Cosmic-ray Conf. (1973) 13th Int. Cosmic-ray Conf., 5, p. 326Acharya, Rao, Sivaprasad, Rao, (1979) 16th Int. Cosmic-ray Conf., 6, p. 289Ellsworth, Goodman, Yodh, Gaisser, Stanev, (1981) Phys. Rev., 23 D, p. 771Bariburina, Guseva, Denisova, (1980) Acta Univ. Lodz, 1, p. 9415th Int. Cosmic-ray Conf. (1977) 15th Int. Cosmic-ray Conf., 7, p. 184(1979) AIP Conf. Proc. no. 49, p. 33
Π ΠΎΠ»Ρ ΠΌΠ΅ΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π³Π΅Π½ΠΎΠ² ΠΌΠΈΠΊΡΠΎΠ ΠΠ Π² ΡΠ°Π·Π»ΠΈΡΠ½ΡΡ ΠΌΠΎΠ»Π΅ΠΊΡΠ»ΡΡΠ½ΠΎ-Π±ΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ ΠΏΠΎΠ΄ΡΠΈΠΏΠ°Ρ ΡΠ°ΠΊΠ° ΠΌΠΎΠ»ΠΎΡΠ½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ
The methylation of CpG islands in the promoter regions of miRNA genes is an epigenetic modification that plays a decisive role in the breast cancer (BC) initiation and progression. The aim of the study was to investigate the frequency of 5 miRNA genes methylation (miRNA-9β1, miRNA-9β3, miRNA-34b/c, miRNA-193A, miRNA-129-2) in mammary epithelial neoplasms. Methylation-specific polymerase chain reaction (MS-PCR) was used to detect methylated genes. 62 patients took part in this study. It was found that the frequency of all 5 miRNAs genes methylation is significantly higher in tumor tissue than in the adjacent histologically unchanged mammary tissue. The authors also performed a correlation analysis and founded a relationship between the methylation rate of certain miRNA genes with some clinical and molecular characteristics of the tumor. This information on epigenetic disorders of BC complements the βmolecular portraitβ of the tumor and can be used to diagnose and assess the prognosis.ΠΠ΅ΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΠΏΡΠΎΠΌΠΎΡΠΎΡΠ½ΡΡ
CpG-ΠΎΡΡΡΠΎΠ²ΠΊΠΎΠ² Π³Π΅Π½ΠΎΠ² ΠΌΠΈΠΊΡΠΎΠ ΠΠ (ΠΌΠΈΠ ΠΠ) ΠΏΡΠΈ ΡΠ°ΠΊΠ΅ ΠΌΠΎΠ»ΠΎΡΠ½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ (Π ΠΠ) β ΡΠΏΠΈΠ³Π΅Π½Π΅ΡΠΈΡΠ΅ΡΠΊΠ°Ρ ΠΌΠΎΠ΄ΠΈΡΠΈΠΊΠ°ΡΠΈΡ, ΠΊΠΎΡΠΎΡΠ°Ρ ΠΈΠ³ΡΠ°Π΅Ρ ΡΠ΅ΡΠ°ΡΡΡΡ ΡΠΎΠ»Ρ Π² ΠΈΠ½ΠΈΡΠΈΠΈΡΠΎΠ²Π°Π½ΠΈΠΈ ΠΈ ΠΏΡΠΎΠ³ΡΠ΅ΡΡΠΈΡΠΎΠ²Π°Π½ΠΈΠΈ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ. Π Π΄Π°Π½Π½ΠΎΠΉ ΡΡΠ°ΡΡΠ΅ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½ΠΎ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅, ΡΠ΅Π»Ρ ΠΊΠΎΡΠΎΡΠΎΠ³ΠΎ β ΠΈΠ·ΡΡΠΈΡΡ ΡΠ°ΡΡΠΎΡΡ ΠΌΠ΅ΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΏΡΡΠΈ Π³Π΅Π½ΠΎΠ² ΠΌΠΈΠ ΠΠ (ΠΌΠΈΠ ΠΠ-9β1, ΠΌΠΈΠ ΠΠ- 9β3, ΠΌΠΈΠ ΠΠ-34b/c, ΠΌΠΈΠ ΠΠ-193a, ΠΌΠΈΠ ΠΠ-129-2) Π² ΡΠΏΠΈΡΠ΅Π»ΠΈΠ°Π»ΡΠ½ΡΡ
ΠΎΠΏΡΡ
ΠΎΠ»ΡΡ
ΠΌΠΎΠ»ΠΎΡΠ½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ. ΠΠ»Ρ Π²ΡΡΠ²Π»Π΅Π½ΠΈΡ ΠΌΠ΅ΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
Π³Π΅Π½ΠΎΠ² ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π»ΡΡ ΠΌΠ΅ΡΠΎΠ΄ ΠΏΠΎΠ»ΠΈΠΌΠ΅ΡΠ°Π·Π½ΠΎΠΉ ΡΠ΅ΠΏΠ½ΠΎΠΉ ΡΠ΅Π°ΠΊΡΠΈΠΈ, ΡΠΏΠ΅ΡΠΈΡΠΈΡΠ½ΠΎΠΉ ΠΊ ΠΌΠ΅ΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΌΡ Π°Π»Π»Π΅Π»Ρ (ΠΠ‘-ΠΠ¦Π ). Π ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΈ ΠΏΡΠΈΠ½ΡΠ»ΠΈ ΡΡΠ°ΡΡΠΈΠ΅ 62 ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΊΠΈ. ΠΠΊΠ°Π·Π°Π»ΠΎΡΡ, ΡΡΠΎ ΡΠ°ΡΡΠΎΡΠ° ΠΌΠ΅ΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π³Π΅Π½ΠΎΠ² Π²ΡΠ΅Ρ
ΠΏΡΡΠΈ ΠΌΠΈΠ ΠΠ Π΄ΠΎΡΡΠΎΠ²Π΅ΡΠ½ΠΎ Π²ΡΡΠ΅ Π² ΠΎΠΏΡΡ
ΠΎΠ»Π΅Π²ΠΎΠΉ ΡΠΊΠ°Π½ΠΈ, ΡΠ΅ΠΌ Π² ΠΏΡΠΈΠ»Π΅ΠΆΠ°ΡΠ΅ΠΉ Π³ΠΈΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈ Π½Π΅ΠΈΠ·ΠΌΠ΅Π½Π΅Π½Π½ΠΎΠΉ ΡΠΊΠ°Π½ΠΈ ΠΌΠΎΠ»ΠΎΡΠ½ΡΡ
ΠΆΠ΅Π»Π΅Π·. ΠΠ²ΡΠΎΡΡ ΡΠ°ΠΊΠΆΠ΅ ΠΏΡΠΎΠ²Π΅Π»ΠΈ ΠΊΠΎΡΡΠ΅Π»ΡΡΠΈΠΎΠ½Π½ΡΠΉ Π°Π½Π°Π»ΠΈΠ· ΠΈ Π²ΡΡΠ²ΠΈΠ»ΠΈ ΡΠ²ΡΠ·Ρ ΡΠ°ΡΡΠΎΡΡ ΠΌΠ΅ΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½Π½ΡΡ
Π³Π΅Π½ΠΎΠ² ΠΌΠΈΠ ΠΠ Ρ Π½Π΅ΠΊΠΎΡΠΎΡΡΠΌΠΈ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΠΌΠΈ ΠΈ ΠΌΠΎΠ»Π΅ΠΊΡΠ»ΡΡΠ½ΡΠΌΠΈ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊΠ°ΠΌΠΈ ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ. ΠΠΎΠ»ΡΡΠ΅Π½Π½ΡΠ΅ Π΄Π°Π½Π½ΡΠ΅ ΠΎΠ± ΡΠΏΠΈΠ³Π΅Π½Π΅ΡΠΈΡΠ΅ΡΠΊΠΈΡ
Π½Π°ΡΡΡΠ΅Π½ΠΈΡΡ
ΠΏΡΠΈ Π ΠΠ Π΄ΠΎΠΏΠΎΠ»Π½ΡΡΡ Β«ΠΌΠΎΠ»Π΅ΠΊΡΠ»ΡΡΠ½ΡΠΉ ΠΏΠΎΡΡΡΠ΅ΡΒ» ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ ΠΈ ΡΠ²Π»ΡΡΡΡΡ ΠΏΠ΅ΡΡΠΏΠ΅ΠΊΡΠΈΠ²Π½ΡΠΌΠΈ ΠΌΠ°ΡΠΊΠ΅ΡΠ°ΠΌΠΈ Π΄Π»Ρ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠΈ ΠΈ ΠΎΡΠ΅Π½ΠΊΠΈ ΠΏΡΠΎΠ³Π½ΠΎΠ·Π°, Π° ΡΠ°ΠΊΠΆΠ΅ ΠΌΠΎΠ³ΡΡ ΡΡΠ°ΡΡ ΠΌΠΈΡΠ΅Π½ΡΡ Π΄Π»Ρ ΡΡΠΏΠ΅ΡΠ½ΠΎΠΉ ΡΠ΅ΡΠ°ΠΏΠΈΠΈ
Broadband quantum light on a fiber-optic platform: From biphotons and heralded single photons to bright squeezed vacuum
Β© 2019 Astro Ltd. Four-wave mixing (FWM) of ultrashort laser pulses in a highly nonlinear photonic-crystal fiber is shown to provide a multimodal source of broadband quantum states of light. In the regime of low pump powers, generation of two-photon states and heralded single photons with a bandwidth up to β6 THz is demonstrated within an FWM-sideband tunability range of β55 THz. In the modality of heralded single-photon generation, three-detector measurements of the conditional second-order correlation function reveal a strong antibunching in the signal-photon channel, with more than 99.2% of the signal counts identified as truly single-photon states. At high pump powers, two-detector signal-idler correlation function measurements indicate broadband bright squeezed vacuum generation
Broadband quantum light on a fiber-optic platform: From biphotons and heralded single photons to bright squeezed vacuum
Β© 2019 Astro Ltd. Four-wave mixing (FWM) of ultrashort laser pulses in a highly nonlinear photonic-crystal fiber is shown to provide a multimodal source of broadband quantum states of light. In the regime of low pump powers, generation of two-photon states and heralded single photons with a bandwidth up to β6 THz is demonstrated within an FWM-sideband tunability range of β55 THz. In the modality of heralded single-photon generation, three-detector measurements of the conditional second-order correlation function reveal a strong antibunching in the signal-photon channel, with more than 99.2% of the signal counts identified as truly single-photon states. At high pump powers, two-detector signal-idler correlation function measurements indicate broadband bright squeezed vacuum generation