1,533 research outputs found
Enjoyment of Sexualization is Associated with Alcohol Use, Self-Objectification is Not
The main purpose of this study was to determine how the enjoyment of sexualization impacts the relationship between self-objectification and alcohol use. Alcohol use is prevalent within college communities and may lead to damaging experiences. Participants were 892 undergraduate women who completed an online questionnaire including measurements of self-objectification, enjoyment of sexualization, as well as an alcohol survey. A general linear model was used to analyze these relationships and interactions. Data analysis showed that while enjoyment of sexualization was associated positively with alcohol use, self-objectification was not, and there was no significant interaction between the two variables. This provides evidence that enjoyment of sexualization is a more significant potential risk factor for drinking behavior than self-objectification. This understanding may lead to the reduction of alcohol consumption risk factors in women through therapies aimed at decreasing enjoyment of sexualization
Changes in metal biogeochemistry resulting from wetland creation: bioavailability, toxicity and risk "WETMAT": final report
In the vicinity of rivers, flooding of available lowlands can be considered as a possibility for temporal storage of river water during high water regimes to minimize the flooding danger of inhabited areas. The creation of wetlands for controlled flooding may also contribute to an increased ecological and biological value of the ecosystem area. Due to industrial activities, river water, sediments and soils are often contaminated with metals. The aim of this study was to determine the changes in the metal biogeochemistry under different hydrological conditions and in the presence of reed plants and how this affects the uptake of metals by plants and invertebrates. Two experimental setups were used. Lab scale experiments consisted of 42 barrels filled up with three different soils and flooded with water of different salinities. For the field scale experiment, 4 tanks filled with two soil types were placed on a platform in the river Scheldt and flooded daily by river water. Results showed that the metal mobility did not depend on the total metal content. Other factors such as soil pH, CEC, redox status and carbonate, OM and clay contents however play an important role in mediating metal behaviour. To prevent the mobilization of the metals, it is advisable to reduce redox variations in the soil. The two-year period of the experiment was too short to detect any measurable changes in most of the soil properties. The measured metal (im)mobilization kinetics can however already be incorporated in models in the near future. These models should allow to predict metal mobility changes at the oxic-anoxic interface upon changing hydrological conditions, where the already existing geochemical models fail due to the fact that they are based on steady state conditions. In the two-year experimental period, large quantities of metal contaminated sediment were found to be deposited on the soils of the tanks which were placed in the river Scheldt. This sedimentation could pose a problem, as it minimizes the water storage capacity of a flood control area. Moreover, the contamination status of alluvial soils should be used as a criterion when selecting new flood control areas as uncontaminated flood control areas are expected to be contaminated when polluted sediments originating from the surrounding surface waters are being deposited or when the soil is contacted with metal-polluted surface water. The latter can be expected in the future, as upon increasing oxygen contents of the river waters due to decreasing organic matter loads, metals can be mobilised from metal-polluted river sediments. Reduction of metal mobility upon increasing oxygen contents of river waters therefore needs further investigation. The metal accumulation in benthic organisms like T. tubifex was found to strongly depend on the inundation period. A higher Zn and Cu accumulation was recorded when substrates were allowed to oxidise. For the talitrid amphipod O. gammarellus, no clear influence was noted. Photosynthetic performance of the reed plants seemed to be mainly determined by other factors than merely metal contamination levels. There was however a possible relation between the abundance of stress enzymes and the metal contamination, making it a more valuable parameter to assess the effect of metals on reed plants in wetlands. The reed itself did not have any measurable effect on the concentration of the metals in the soil or pore water. Also no differences in the concentrations of metals in the reed biomass or differences in the reed growth were observed between the contaminated and uncontaminated soil
A fast parallel squarer based on divide-and-conquer
Journal ArticleFast and small squarers are needed in many applications such as image compression. A new family of high performance parallel squarers based on the divide-and-conquer method is reported. Our main result was realizing the basis cases of the divide-and-conquer recursion by using optimized n-bit primitive squarers, where n is in the range of 2 to 6. This method reduced the gate count and provided shorter critical paths. A chip implementing an 8-bit squarer was designed, fabricated and successfully tested, resulting in 24 MOPS using a 2-p CMOS fabrication technology. This squarer had two additional features: increased number of squaring operations per unit circuit area, and the potential for reduced power consumption per squaring operation
Automatic rapid prototyping of semi-custom VLSI circuits using FPGAs
Journal ArticleWe describe a technique for translating semi-custom VLSI circuits automatically, integrating two design environments, into field programmable gate arrays (FPGAs) for rapid and inexpensive prototyping. The VLSI circuits are designed using a cell-matrix based environment that produces chips with density comparable to full custom VLSI design. These circuits are translated automatically into FPGAs for testing and system development. A four-bit pipelined array multiplier is used as an example of this translation. The multiplier is implemented in CMOS in both synchronous and asynchronous pipelined versions, and translated into Actel FPGAs both automatically, and by hand for comparison. The six test chips were all found to be fully functional, and the translation efficiency in terms of chip speed and area is shown. This result demonstrates the potential of this approach to system development
Objective Prediction of Pharyngeal Swallow Dysfunction in Dysphagia through Artificial Neural Network Modelling
This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving'. © 2016 John Wiley & Sons LtdBackground
Pharyngeal pressure-flow analysis (PFA) of high resolution impedance-manometry (HRIM) with calculation of the swallow risk index (SRI) can quantify swallow dysfunction predisposing to aspiration. We explored the potential use of artificial neural networks (ANN) to model the relationship between PFA swallow metrics and aspiration and to predict swallow dysfunction.
Methods
Two hundred consecutive dysphagia patients referred for videofluoroscopy and HRIM were assessed. Presence of aspiration was scored and PFA software derived 13 metrics and the SRI. An ANN was created and optimized over training cycles to achieve optimal classification accuracy for matching inputs (PFA metrics) to output (presence of aspiration on videofluoroscopy). Application of the ANN returned a value between 0.00 and 1.00 reflecting the degree of swallow dysfunction.
Key Results
Twenty one patients were excluded due to insufficient number of swallows (<4). Of 179, 58 aspirated and 27 had aspiration pneumonia history. The SRI was higher in aspirators (aspiration 24 [9, 41] vs no aspiration 7 [2, 18], p < 0.001) and patients with pneumonia (pneumonia 27 [5, 42] vs no pneumonia 8 [3, 24], p < 0.05). The ANN Predicted Risk was higher in aspirators (aspiration 0.57 [0.38, 0.82] vs no aspiration 0.13 [0.4, 0.25], p < 0.001) and in patients with pneumonia (pneumonia 0.46 [0.18, 0.60] vs no pneumonia 0.18 [0.6, 0.49], p < 0.01). Prognostic value of the ANN was superior to the SRI.
Conclusions & Inferences
In a heterogeneous cohort of dysphagia patients, PFA with ANN modeling offers enhanced detection of clinically significant swallowing dysfunction, probably more accurately reflecting the complex interplay of swallow characteristics that causes aspiration
Reducing the burden of hypoglycaemia in people with diabetes through increased understanding:design of the Hypoglycaemia Redefining Solutions for Better Lives (Hypo-RESOLVE) project
Background
Hypoglycaemia is the most frequent complication of treatment with insulin or insulin secretagogues in people with diabetes. Severe hypoglycaemia, i.e. an event requiring external help because of cognitive dysfunction, is associated with a higher risk of adverse cardiovascular outcomes and all‐cause mortality, but underlying mechanism(s) are poorly understood. There is also a gap in the understanding of the clinical, psychological and health economic impact of ‘non‐severe’ hypoglycaemia and the glucose level below which hypoglycaemia causes harm.
Aim
To increase understanding of hypoglycaemia by addressing the above issues over a 4‐year period.
Methods
Hypo‐RESOLVE is structured across eight work packages, each with a distinct focus. We will construct a large, sustainable database including hypoglycaemia data from >100 clinical trials to examine predictors of hypoglycaemia and establish glucose threshold(s) below which hypoglycaemia constitutes a risk for adverse biomedical and psychological outcomes, and increases healthcare costs. We will also investigate the mechanism(s) underlying the antecedents and consequences of hypoglycaemia, the significance of glucose sensor‐detected hypoglycaemia, the impact of hypoglycaemia in families, and the costs of hypoglycaemia for healthcare systems.
Results
The outcomes of Hypo‐RESOLVE will inform evidence‐based definitions regarding the classification of hypoglycaemia in diabetes for use in daily clinical practice, future clinical trials and as a benchmark for comparing glucose‐lowering interventions and strategies across trials. Stakeholders will be engaged to achieve broadly adopted agreement.
Conclusion
Hypo‐RESOLVE will advance our understanding and refine the classification of hypoglycaemia, with the ultimate aim being to alleviate the burden and consequences of hypoglycaemia in people with diabetes
Speciation of vanadium in the dissolved, colloidal, and sediment phase under dynamic redox-conditions in a V contaminated soil treated and untreated with biochar
Vanadium is a redox-sensitive toxic element and can exist in a variety of oxidation states: −1, 0, +2, +3, +4, and +5. Vanadium (+5) is considered as a potentially dangerous pollutant. Biochar (BC) can be used to remediate soils contaminated with potential toxic elements (PTEs) including V. However, the efficiency of BC to immobilize V and its on speciation of V in the dissolved and colloidal phase and its mobilization and phytoavailability in the sediment phase under dynamic redox-conditions in highly contaminated soils under dynamic redox conditions has not been studied up to date. Thus, we have i) quantified the impact of pre-definite redox conditions on the speciation and release dynamics of V in the dissolved and colloidal phase as well as on the mobilization and phytoavailability of V in the soil sediments phase in a highly contaminated alkaline soil (CS) (non-treated) (pH = 7.44 and total V = 1,040 mg kg-1) collected from China and in the same soil treated with BC (CS+BC), and ii) assessed the impact of rice husk biochar as soil amendment on the same parameters. The impact of redox potential (EH), pH, dissolved organic carbon (DOC), dissolved inorganic carbon (DIC), iron (Fe), manganese (Mn), and sulfate (SO42-) on speciation and release dynamics of V was also determined under dynamic redox conditions. In addition, the used biochar was characterized using scanning electron microscopy (SEM) coupled with energy dispersive X-ray spectroscopy (EDX) and nuclear magnetic resonance spectroscopy (NMR). The experiment was conducted in stepwise from moderate reducing (-30 mV in CS and -12 mV in CS+BC) to oxidizing (+218 mV in CS and +333 mV in CS+BC) soil conditions in different cycles using a highly sophisticated automated biogeochemical microcosm apparatus.
Flooding of the CS and CS+BC caused significant changes of pH values which varied from 6.15 to 8.33 in the CS and from 5.14 to 7.91 in the CS+BC and the EH correlated negatively with pH. The dissolved concentrations of V varied from 15.2-46.4 mg L-1 in the CS to 14.9-50.2 mg L-1 in the CS+BC, while the colloidal concentrations of V varied from 39.5-49.9 mg L-1 in the CS to 31.8-50.2 mg L-1 in the CS+BC.
Different redox cycles affected significantly the speciation and release dynamics of V in the dissolved and colloidal phase and its mobilization and phytoavailability in the sediment phase
- …