FAPRP: A Machine Learning Approach to Flooding Attacks Prevention Routing Protocol in Mobile Ad Hoc Networks

© 2019 Ngoc T. Luong et al. Request route flooding attack is one of the main challenges in the security of Mobile Ad Hoc Networks (MANETs) as it is easy to initiate and difficult to prevent. A malicious node can launch an attack simply by sending an excessively high number of route request (RREQ) packets or useless data packets to nonexistent destinations. As a result, the network is rendered useless as all its resources are used up to serve this storm of RREQ packets and hence unable to perform its normal routing duty. Most existing research efforts on detecting such a flooding attack use the number of RREQs originated by a node per unit time as the threshold to classify an attacker. These algorithms work to some extent; however, they suffer high misdetection rate and reduce network performance. This paper proposes a new flooding attacks detection algorithm (FADA) for MANETs based on a machine learning approach. The algorithm relies on the route discovery history information of each node to capture similar characteristics and behaviors of nodes belonging to the same class to decide if a node is malicious. The paper also proposes a new flooding attacks prevention routing protocol (FAPRP) by extending the original AODV protocol and integrating FADA algorithm. The performance of the proposed solution is evaluated in terms of successful attack detection ratio, packet delivery ratio, and routing load both in normal and under RREQ attack scenarios using NS2 simulation. The simulation results show that the proposed FAPRP can detect over 99% of RREQ flooding attacks for all scenarios using route discovery frequency vector of sizes larger than 35 and performs better in terms of packet delivery ratio and routing load compared to existing solutions for RREQ flooding attacks

MLAMAN: a novel multi-level authentication model and protocol for preventing wormhole attack in mobile ad hoc network

© 2018, Springer Science+Business Media, LLC, part of Springer Nature. Wormhole attack is a serious security issue in Mobile Ad hoc Network where malicious nodes may distort the network topology and obtain valuable information. Many solutions, based on round trip time, packet traversal time, or hop-count, have been proposed to detect wormholes. However, these solutions were only partially successful in dealing with node high-speed mobility, variable tunnel lengths, and fake information by malicious nodes. To address those issues, this paper proposes a novel multi-level authentication model and protocol (MLAMAN) for detecting and preventing wormhole attacks reliably. MLAMAN allows all intermediate nodes to authenticate control packets on a hop-by-hop basis and at three levels: (1) the packet level where the integrity of the packets can be verified, (2) the node membership level where a public key holder-member can be certified, and (3) the neighborhood level where the neighborhood relationship between nodes can be determined. The novelty of the model is that it prevents malicious nodes from joining the network under false information and pretense. It detects wormhole nodes effectively under various scenarios including variable tunnel lengths and speeds of moving nodes. The effectiveness of our approach is confirmed by simulation results through various scenarios

Identification of possible virulence marker from Campylobacter jejuni isolates

This is the final version of the article. Available from the publisher via the DOI in this record.A novel protein translocation system, the type-6 secretion system (T6SS), may play a role in virulence of Campylobacter jejuni. We investigated 181 C. jejuni isolates from humans, chickens, and environmental sources in Vietnam, Thailand, Pakistan, and the United Kingdom for T6SS. The marker was most prevalent in human and chicken isolates from Vietnam.The work was partly supported by the UK Biotechnology and Biological Sciences Research Council, award BB/1024631/1 to R.T., D.S., and O.C.; by a Wellcome Trust Institutional Strategic Support Award (WT097835MF); and by a studentship awarded to J.H. Mr Harrison is a PhD student at the University of Exeter under the supervision of D.S. His research focuses on using bioinformatic methods to investigate the comparative genomics of emerging diseases and plant-associated microbes

Detection and monitoring of cancers with biosensors in Vietnam

Biosensors are able to provide fast, accurate and reliable detec-tions and monitoring of cancer cells, as well as to determine the effectiveness of anticancer chemotherapy agents in cancer treatments. These have attracted a great attention of research communities, especially in the capabilities of detecting the path-ogens, viruses and cancer cells in narrow scale that the conven-tional apparatus and techniques do not have. This paper pre-sents technologies and applications of biosensors for detections of cancer cells and related diseases, with the focus on the cur-rent research and technology development about biosensors in Vietnam, a typical developing country with a very high number of patients diagnosed with cancers in recent years, but having a very low cancer survival rate. The role of biosensors in early detections of diseases, cancer screening, diagnosis and treat-ment, is more and more important; especially it is estimated that by 2020, 60-70% new cases of cancers and nearly 70% of cancer deaths will be in economically disadvantaged countries. The paper is also aimed to open channels for the potential R&D collaborations with partners in Vietnam in the areas of innovative design and development of biosensors in particular and medical technology devices in general

Offloading Energy Efficiency with Delay Constraint for Cooperative Mobile Edge Computing Networks

© 2018 IEEE. We propose a novel edge computing network architecture that enables edge nodes to cooperate in sharing computing and radio resources to minimize the total energy consumption of mobile users while meeting their delay requirements. To find the optimal task offloading decisions for mobile users, we first formulate the joint task offloading and resource allocation optimization problem as a mixed integer non-linear programming (MINLP). The optimization involves both binary (offloading decisions) and real variables (resource allocations), making it an NP-hard and computational intractable problem. To circumvent, we relax the binary decision variables to transform the MINLP to a relaxed optimization problem with real variables. After proving that the relaxed problem is a convex one, we propose two solutions namely ROP and IBBA. ROP is adopted from the interior point method and IBBA is developed from the branch and bound algorithm. Through the numerical results, we show that our proposed approaches allow minimizing the total energy consumption and meet all delay requirements for mobile users

A formal proof of the Kepler conjecture

This article describes a formal proof of the Kepler conjecture on dense sphere packings in a combination of the HOL Light and Isabelle proof assistants. This paper constitutes the official published account of the now completed Flyspeck project

Adaptive remodeling of the bacterial proteome by specific ribosomal modification regulates Pseudomonas infection and niche colonisation

Post-transcriptional control of protein abundance is a highly important, underexplored regulatory process by which organisms respond to their environments. Here we describe an important and previously unidentified regulatory pathway involving the ribosomal modification protein RimK, its regulator proteins RimA and RimB, and the widespread bacterial second messenger cyclic-di-GMP (cdG). Disruption of rimK affects motility and surface attachment in pathogenic and commensal Pseudomonas species, with rimK deletion significantly compromising rhizosphere colonisation by the commensal soil bacterium P. fluorescens, and plant infection by the pathogens P. syringae and P. aeruginosa. RimK functions as an ATP-dependent glutamyl ligase, adding glutamate residues to the C-terminus of ribosomal protein RpsF and inducing specific effects on both ribosome protein complement and function. Deletion of rimK in P. fluorescens leads to markedly reduced levels of multiple ribosomal proteins, and also of the key translational regulator Hfq. In turn, reduced Hfq levels induce specific downstream proteomic changes, with significant increases in multiple ABC transporters, stress response proteins and non-ribosomal peptide synthetases seen for both ΔrimK and Δhfq mutants. The activity of RimK is itself controlled by interactions with RimA, RimB and cdG. We propose that control of RimK activity represents a novel regulatory mechanism that dynamically influences interactions between bacteria and their hosts; translating environmental pressures into dynamic ribosomal changes, and consequently to an adaptive remodeling of the bacterial proteome

Effectiveness and Safety of Radiofrequency Catheter Ablation Using Three-Dimensional Electroanatomic Mapping Systems in Treating Ventricular Arrhythmias: A Single-Center Prospective Cohort Study in Vietnam

Le Uyen Phuong Tran,1 Ngoc Dung Kieu,1 Cao Dat Tran,1 Tri-Thuc Nguyen,1 Van Sy Hoang,2 Truc Thanh Thai3 1Department of Arrhythmology, Cho Ray Hospital, Ho Chi Minh City, Vietnam; 2Department of Internal Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam; 3Department of Medical Statistics and Informatics, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, VietnamCorrespondence: Truc Thanh Thai, Department of Medical Statistics and Informatics, University of Medicine and Pharmacy at Ho Chi Minh City, 217 Hong Bang Street, Ward 11, District 5, Ho Chi Minh City, 700000, Vietnam, Tel +84 908381266, Email [email protected]: Advanced catheter ablation using three-dimensional electroanatomic mapping (EAM) has shown favorable outcomes in high-income countries, but real-world evidence from low- and middle-income settings is scarce. This study aimed to assess the clinical characteristics, procedural features, and outcomes of radiofrequency ablation using EAM in patients with ventricular tachycardia (VT) or premature ventricular contractions (PVCs) at a tertiary cardiac center in Vietnam.Methods: We analyzed 233 patients who underwent VT and PVC ablation at Cho Ray Hospital from March 2021 to December 2023. Patients were categorized into two groups based on left ventricular ejection fraction (LVEF) with the cut-off value of 50%: reduced (LVEF < 50%, n = 39) and preserved (LVEF ≥ 50%, n = 194). Data on demographics, arrhythmia burden, ablation protocol, and follow-up outcomes were collected and compared.Results: Patients with reduced LVEF more frequently presented with ventricular tachycardia (23.1% vs 6.7%, p < 0.001), ischemic heart disease (23.1% vs 7.7%, p = 0.008), and were more likely to require irrigated catheters (46.2% vs 20.1%, p = 0.001). The PVC burden prior to ablation was significantly different between groups (36.3% ± 17.2 vs 27.8% ± 12.2, p = 0.014) and patients with reduced LVEF exhibited remarkable recovery after ablation, with LVEF improving from 33.7 ± 8.1 to 55.2 ± 9.1 (p < 0.001). The acute ablation success rate was 100% in both groups. The procedure demonstrated high levels of safety, with a non-severe complication rate of 4.7% (n = 11) and low radiation exposure (median 16 mGy [inter-quartile range: 11– 26]).Conclusion: Catheter ablation is highly effective and safe in treating ventricular arrhythmias across different LVEF, especially in ventricular arrhythmia-induced cardiomyopathy group, leading to rapid recovery of left ventricular function and reduction in arrhythmia burden. These findings provide important real-world evidence from a resource limited setting, providing multiple use of catheters and skin patches.Keywords: safety, effectiveness, ventricular arrhythmias induced cardiomyopathy, radiofrequency catheter ablation, heart failur

Factors associated with a low prevalence of exclusive breastfeeding during hospital stay in urban and semi-rural areas of southern Vietnam.

BACKGROUND: There is a paucity of data regarding risk factors associated with suboptimal breastfeeding practices in urbanized areas of low-middle income countries (LMICs). METHODS: Through a large prospective birth cohort, which enrolled 6706 infants in Vietnam between 2009 and 2013, we investigated the practice of exclusive breastfeeding during hospital stay in urban and semi-rural populations and aimed to identify factors associated with suboptimal breastfeeding practices. Univariate and multivariable logistic regression were performed to determine factors associated with not exclusive breastfeeding during hospital stay. RESULTS: Of 6076 mothers, 33% (2187) breastfed their infant exclusively before hospital discharge; 9% (364/4248) in urban and 74% (1823/2458) in semi-rural areas. Exclusive breastfeeding up to 4 months was recorded in 15% (959/6210) of participants; this declined to < 1% (56/6093) at 6 months. Delivery by Caesarean section (Odds Ratio [OR] 0.07; 95% Confidence Interval [CI] 0.04, 0.11 and OR 0.05; 95% CI 0.03, 0.08) and neonatal complications (OR 0.2; 95% CI 0.07, 0.47 and OR 0.25; 95% CI 0.14, 0.46) were common and highly significant risk factors associated with a lack of exclusive breastfeeding during hospital stay in urban and semi-rural settings, respectively. CONCLUSIONS: To our knowledge, this is the first large-scale investigation aimed at identifying factors associated with exclusive breastfeeding during hospital stay in Vietnam. Breastfeeding promotion strategies should prioritize common risk factors in hospital, such as Caesarean section and neonatal complications, and other location specific factors associated with socioeconomics

Search for Gravitational Waves from Primordial Black Hole Binary Coalescences in the Galactic Halo

We use data from the second science run of the LIGO gravitational-wave detectors to search for the gravitational waves from primordial black hole (PBH) binary coalescence with component masses in the range 0.2--$1.0 M_\odot$. The analysis requires a signal to be found in the data from both LIGO observatories, according to a set of coincidence criteria. No inspiral signals were found. Assuming a spherical halo with core radius 5 kpc extending to 50 kpc containing non-spinning black holes with masses in the range 0.2--$1.0 M_\odot$, we place an observational upper limit on the rate of PBH coalescence of 63 per year per Milky Way halo (MWH) with 90% confidence.Comment: 7 pages, 4 figures, to be submitted to Phys. Rev.