Undifferentiated Sarcoma of the Salivary Gland in a Mongolian Gerbil (Meriones unguiculatus)

A subcutaneous mass was found in the lower ventral neck region of a 55-week-old male Mongolian gerbil (Meriones unguiculatus). Histopathologically, the mass involved salivary glands and featured diffuse proliferation of pleomorphic neoplastic cells with large necrotic foci. The lesion was well demarcated from the surrounding tissue, although invasive growth to fibrous septa was occasionally observed. The neoplastic cells were mainly arranged in irregular sheets with severe cellular atypia, round to oval nuclei and varying amounts of eosinophilic cytoplasm. Mitotic figures and multinucleated giant cells were frequent. Immunohistochemical analysis revealed that the neoplastic cells were strongly positive for vimentin and S-100 and negative for NSE, cytokeratin, α-SMA, c-kit, factor VIII, CD34, α-1-antitrypsin, lysozyme and MSR-A. Based on the results, the mass was diagnosed as an undifferentiated sarcoma of the salivary gland. To the best of our knowledge, this is the first report of such a tumor in Mongolian gerbils

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

Generalized tendency to make extreme trait judgements from faces

People differ in their tendency to infer others' personalities and abilities from their faces. An extreme form of such face-based trait inference (FBTI) is problematic because of its unwarranted impact on real-world decision making. Evolutionary perspectives on FBTI suggest that its inter-individual variation would be trait-specific: e.g. those who make extreme face-based inferences about trustworthiness may not necessarily do so about dominance. However, there are several psychological variables that can increase the FBTI extremity across traits. Here, we show that there is a generalized individual tendency to make extreme FBTI across traits, in support of the latter view. We found that the degrees of extremity of face-based inferences about seven traits had high cross-trait correlations, constituting a general factor. This generalized FBTI extremity had good test–retest reliability and was neither an artefact of extreme nor socially desirable response biases. Moreover, it was positively associated with facial emotion recognition ability and tendencies to believe physiognomy and endorse stereotypes. Our results demonstrate that there are individuals who have a temporally stable disposition to draw extreme conclusions about various traits of others from facial appearance as well as their psychological characteristics

Perceived threat to national values in evaluating stereotyped immigrants

<p>The present research examined the psychological reasons behind Americans’ (un)willingness to accept immigrants. Participants read a scenario depicting immigrant groups allegedly expected to arrive in the United States and evaluated how much the immigrants would influence two types of American national values: civic values (e.g., political ideology) and ethnic values (e.g., shared culture and customs). Across three studies, competitive immigrant groups were stereotyped to be untrustworthy and perceived to threaten American civic values, but not ethnic values. Value threat then mediated the predicted competition–prejudice relationship in Study 3. Perceived vulnerability of in-group boundary might specify one motivated cause of derogating immigrants.</p

Gender Stereotypes and Expected Backlash for Female STEM Students in Germany and Japan

Although Germany and Japan are top-ranking in STEM, women are underrepresented in the STEM fields of physics, engineering, and computer science in both countries. The current research investigated widespread gender-science stereotypes in STEM in the two countries (Studies 1 and 2) and negative consequences of expected backlash (i.e., imagining negative reactions and lower ascribed communion in scenarios) for women’s emotions and motivation in STEM due to role incongruity and lack-of-fit (Study 3). Studies 1 (N = 87) and 2 (N = 22,556) showed that explicit and implicit gender-science stereotypes are widespread and comparable in Germany and Japan. Study 3 (N = 628) showed that lower ascribed communion was related to less positive emotions, more negative emotions and anxiety emotions, and less study motivation for STEM students (from the fields of physics, engineering, and computer science) from Germany and Japan. Results point to more subtle expected backlash effects for women in STEM than hypothesized. Theoretical and practical implications for gender equality in STEM are discussed.publishe