Aspectos fisiológicos de grãos de café produzidos em ambientes variados da micro região da Serra da Mantiqueira.

O ambiente exerce forte influência sobre os frutos do café ao longo do desenvolvimento e maturação das sementes, quando vários compostos são sintetizados ou quimicamente alterados, o que também acontece durante o processamento. Isso pode influenciar a obtenção de sementes de melhor qualidade fisiológica, que está intimamente ligada à qualidade sensorial da bebida. Assim sendo, o presente trabalho teve como objetivo avaliar a qualidade fisiológica dos cafés da microrregião da Serra da Mantiqueira, colhidos em ambientes distintos e processados via seca e via úmida. O experimento foi realizado em esquema fatorial (2 x 2 x 3 x 2) com 3 repetições, sendo dois processamentos, natural e desmucilado; duas cultivares, Acaiá e Bourbon Amarelo; três intervalos de altitude (1200m); e duas faces de exposição ao sol, soalheiro (NE, N, NO,O) e contra-face (L, SE, S, SO) caracterizando o ambiente de produção. O café foi colhido manualmente selecionando-se apenas os frutos maduros, os quais foram processados via seca e via úmida, obtendo-se os cafés naturais e desmucilados, e então secados em terreiro de concreto ao sol até atingirem o teor de água de 11% (bu). As análises fisiológicas realizadas por meio do teste de germinação, onde foram avaliadas as seguintes características nas sementes: porcentagem de protrusão radicular, de plântulas normais aos 30 dias e de folhas cotiledonares abertas aos 45 dias. A protrusão radicular, plântulas normais e folhas cotiledonares abertas foram maiores nos cafés processados via úmida (p<0,05), sendo que para folhas cotiledonares abertas aos 45 dias a variedade Bourbon Amarelo se sobressaiu em relação ao Acaiá (p<0,05), demonstrando um potencial maior desta variedade para qualidade fisiológica. O processamento via úmida é menos prejudicial à qualidade fisiológica do

Eco-efficiency of forestry companies around the world: a data envelopment analysis.

Objective: to evaluate and compare the economic, environmental, and eco-efficiency of companies operating in the forestry sector and fill the gap in relation to the lack of information about the theme. Theoretical framework: increased awareness of society around the traditional productive model and its impact on the environment demands that companies associate business competitiveness with environmental responsibility. Therefore, the disclosure of information and the analysis of it using methods such as the eco-efficiency approach are important to monitor the performance of companies. Methods: the Data Envelopment Analysis method was used with three proposed models: economic (desirable output); environmental with undesirable variables; and eco-efficiency model with desirable and undesirable variables. Results and conclusions: results show that the years 2009-2010 and 2016-2017 were more favorable to technical efficiency, while ecological efficiency was higher from 2010 to 2012. Meanwhile, the highest average eco-efficiency score was registered in 2013. In the 11 years analyzed, Portugal, Canada, United Kingdom, Australia, South Africa, and Spain stood out as the most eco-efficient countries. Research implications: the eco-efficiency approach demonstrated and discussed in this research can be used to monitor forestry companies' performance taking into account their productivity and environmental impact reduction. Originality/value: this study presents a comprehensive evaluation of silviculture companies worldwide using the technical, environmental, and eco-efficiency models. Analyses are based on financial and environmental data of 82 publicly listed companies from 23 countries, including developed and developing economies and cover the period of 11 years (2009 to 2019)

Óleos essenciais de espécies do gênero Aniba

Most Aniba (Lauraceae) species occur in Amazonia. They are represented by trees which contain essential oil in all of their organs. Oils from different organs of any species show little variation in composition. In contradistinction, such surprisingly drastic variation may be noted among different species, that they can be classified into groups. The linalool - group comprises A. duckei Kosterm. and A. rosaeodora Ducke. The benzyl benzoate - group comprises A. burchellii Kosterm., A. firmula (Nees et Mart.) Mez., A. fragrans Ducke, A. gardneri (Meissn.) Mez, A. guianensis Aubl., A. parviflora (Meissn.) Mez and A. permollis (Nees) Mez. The allylbenzene - group comprises A. canelilla (H.B.K.) Mez. A. hostmanniana (Nees) Mez and A. pseudocoto (Rusby) Kosterm. Detailed analysis revealed the presence in some of these oils of such rare plant products as l-nitro-2-phenylethane, phenylathyl benzoate, O-methylisoeugenol and 2, 4, 5-trimethoxyallylbenzene.A maior parte das espécies de Aniba (Lauraceae) se encontra na Amazônia. São representadas por árvores que contêm óleo essencial em todos os seus órgãos. Os óleos dos diferentes órgãos de qualquer espécie mostram somente uma pequena variação em sua composição. Em contrapartida, pode ser notada uma variação tão surpreendentemente drástica entre espécies diferentes que podem ser classificadas em grupos. O grupo linalol compreende A. duckei Kosterm. e A. rosaeodora Ducke. O grupo benzoato de benzilo compreende A. burchellii Kosterm., A. firmula (Nees & Mart.) Mez., A. fragrans Ducke, A. gardneri (Meissn.) Mez, A. guianensis Aubl., A. parviflora (Meissn.) Mez. e A. permollis (Nees) Mez. O grupo alilbenzeno compreende A. canelilla (H.B.K.) Mez., A. hostmanniana (Nees) Mez e A. pseudocoto (Rusby) Kosterm. A análise detalhada revelou a presença, em alguns destes óleos ,de produtos raros de plantas como l-nitro-2feniletano, benzoato de feniletilo O-metilisoeugenol e 2, 4, 5-trimetoxialilbenzeno

Plano de fortalecimento da cadeia produtiva da apicultura e da meliponicultura do Estado de São Paulo.

A cadeia produtiva dos produtos das abelhas é uma importante atividade econômica que gera emprego e renda. São apicultores, meliponicultores, processadores, varejistas e exportadores que contribuem para o desenvolvimento social e econômico do Estado de São Paulo. Além disso, o setor fornece alimentos de altíssima qualidade biológica e nutricional e contribui para a segurança alimentar.bitstream/item/199996/1/13377-plano-de-fortalecimento-da-cadeia-da-apicultura-e-meliponicultura-10-dez-2018.pdfDocumento online. Link de acesso: https://www.agricultura.sp.gov.br/MEDIA/13375-PLANO-DE-FORTALECIMENTO-DA-CADEIA-DA-APICULTURA-E-MELIPONICULTURA-10-DEZ-2018.PDF

[ARIA 2019: An Integrated Care Pathway for Allergic Rhinitis in Portugal]

The Allergic Rhinitis and Its Impact on Asthma (ARIA) initiative started more than 20 years ago and has developed and disseminated evidence-based guidelines and projects in the field of allergic rhinitis. This initiative is currently focused on providing patient-centred guidelines that contribute to an integrated care pathway between the various levels of care and take advantage of digital solutions, and the introduction of integrated care pathways in clinical practice has been recommended. In this article we describe the adaptation for Portugal of the ARIA Integrated Care Pathways document. After a brief review of the epidemiology and impact of allergic rhinitis in Portugal and the activities carried out in Portugal within the ARIA initiative, we describe the broad knowledge base used for the development of recommendations for the pharmacological treatment of allergic rhinitis, and these recommendations are based on the GRADE methodology, real world evidence acquired by mobile technology (mHealth) and resulting from allergenic exposure chamber studies. What follows is a summary of integrated care pathways for allergen immunotherapy produced in 2019. Allergen immunotherapy is considered an example of precision medicine where the use of mHealth technologies will improve stratification for patient selection and response monitoring. These recommendations were considered as best practices of integrated patient-centred care supported by digital systems from Directorate General for Health and Food Safety of the European Union (DG Santé) and represent the ARIA Phase 4 Change Management strategy.info:eu-repo/semantics/publishedVersio

Origin and Epidemiological History of HIV-1 CRF14_BG

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Users must also make clear the license terms under which the work was published. CC BY Licence: http://creativecommons.org/licenses/by/4.0/Background: CRF14_BG isolates, originally found in Spain, are characterized by CXCR4 tropism and rapid disease progression. This study aimed to identify the origin of CRF14_BG and reconstruct its epidemiological history based on new isolates from Portugal.Methodology/Principal Findings: C2V3C3 env gene sequences were obtained from 62 samples collected in 1993–1998 from Portuguese HIV-1 patients. Full-length genomic sequences were obtained from three patients. Viral subtypes, diversity, divergence rate and positive selection were investigated by phylogenetic analysis. The molecular structure of the genomes was determined by bootscanning. A relaxed molecular clock model was used to date the origin of CRF14_BG. Geno2pheno was used to predict viral tropism. Subtype B was the most prevalent subtype (45 sequences; 73%) followed by CRF14_BG (8; 13%), G (4; 6%), F1 (2; 3%), C (2; 3%) and CRF02_AG (1; 2%). Three CRF14_BG sequences were derived from 1993 samples. Near full-length genomic sequences were strongly related to the CRF14_BG isolates from Spain. Genetic diversity of the Portuguese isolates was significantly higher than the Spanish isolates (0.044 vs 0.014, P,0.0001). The mean date of origin of the CRF14_BG cluster was estimated to be 1992 (range, 1989 and 1996) based on the subtype G genomic region and 1989 (range, 1984–1993) based on the subtype B genomic region. Most CRF14_BG strains (78.9%) were predicted to be CXCR4. Finally, up to five amino acids were under selective pressure in subtype B V3 loop whereas only one was found in the CRF14_BG cluster.Conclusions: CRF14_BG emerged in Portugal in the early 1990 s soon after the beginning of the HIV-1 epidemics, spread to Spain in late 1990 s as a consequence of IVDUs migration and then to the rest of Europe. CXCR4 tropism is a general characteristic of this CRF that may have been selected for by escape from neutralizing antibody response

Spread of yellow fever virus outbreak in Angola and the Democratic Republic of the Congo 2015-16: a modelling study.

BACKGROUND: Since late 2015, an epidemic of yellow fever has caused more than 7334 suspected cases in Angola and the Democratic Republic of the Congo, including 393 deaths. We sought to understand the spatial spread of this outbreak to optimise the use of the limited available vaccine stock. METHODS: We jointly analysed datasets describing the epidemic of yellow fever, vector suitability, human demography, and mobility in central Africa to understand and predict the spread of yellow fever virus. We used a standard logistic model to infer the district-specific yellow fever virus infection risk during the course of the epidemic in the region. FINDINGS: The early spread of yellow fever virus was characterised by fast exponential growth (doubling time of 5-7 days) and fast spatial expansion (49 districts reported cases after only 3 months) from Luanda, the capital of Angola. Early invasion was positively correlated with high population density (Pearson's r 0·52, 95% CI 0·34-0·66). The further away locations were from Luanda, the later the date of invasion (Pearson's r 0·60, 95% CI 0·52-0·66). In a Cox model, we noted that districts with higher population densities also had higher risks of sustained transmission (the hazard ratio for cases ceasing was 0·74, 95% CI 0·13-0·92 per log-unit increase in the population size of a district). A model that captured human mobility and vector suitability successfully discriminated districts with high risk of invasion from others with a lower risk (area under the curve 0·94, 95% CI 0·92-0·97). If at the start of the epidemic, sufficient vaccines had been available to target 50 out of 313 districts in the area, our model would have correctly identified 27 (84%) of the 32 districts that were eventually affected. INTERPRETATION: Our findings show the contributions of ecological and demographic factors to the ongoing spread of the yellow fever outbreak and provide estimates of the areas that could be prioritised for vaccination, although other constraints such as vaccine supply and delivery need to be accounted for before such insights can be translated into policy. FUNDING: Wellcome Trust