The decays omega(782), phi(1020) to 5 pi in the hidden local symmetry approach

The decays omega -> 2pi^+ 2pi^- pi^0 and omega -> pi^+ pi^- 3pi^0 are reconsidered in the hidden local symmetry approach (HLS) added with the anomalous terms. The decay amplitudes are analyzed in detail, paying the special attention to the Adler condition of vanishing the whole amplitude at vanishing momentum of any final pion. Combining the Okubo-Zweig-Iizuka (OZI) rule applied to the five pion final state, with the Adler condition, we calculate also the phi -> 2pi^+ 2pi^-pi^0 and phi -> pi^+ pi^- 3pi^0 decay amplitudes. The partial widths of the above decays are evaluated, and the excitation curves in e^+e^- annihilation are obtained, assuming reasonable particular relations among the parameters characterizing the anomalous terms of the HLS Lagrangian. The evaluated branching ratios B(phi -> pi^+ pi^- 3pi^0)~2x10^{-7} and B(phi -> 2pi^+ 2pi^- pi^0)~7x10^{-7} are such that with the luminosity L=500 pb^{-1} attained at DAFNE phi factory, one may already possess about 1685 events of the decays phi -> 5pi.Comment: 15 pages text, 12 pages of figures. Typos corrected, clarifying remarks added. Accepted for publication in Phys.Rev.

Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362

Vitamin D Status in Adolescents during COVID-19 Pandemic: A Cross-Sectional Comparative Study.

Vitamin D has been claimed to be effective in the response to infections, including the respiratory syndrome coronavirus 2 (SARS-CoV-2). It is supposed that lockdown measures and fear of SARS-CoV-2 infection might reduce vitamin D levels through the modification of lifestyle. However, very few data exist on the association between lockdown measures and vitamin D status in humans. For this cross-sectional comparative study, adolescents (n = 298) aged 18 to 19 years were enrolled during the compulsory military fitness-for-duty evaluation between July and December 2020 in Southern Switzerland. Beyond anthropometric measurements, participants filled in a structured questionnaire about their lifestyle and a blood specimen was sampled for the determination of total 25-hydroxy-vitamin D. The obtained data were compared with those of 437 adolescents enrolled at the military fitness-for-duty evaluation during the same period of the year in the context of the CENERI study (2014-2016). The anthropometric measures were similar between the two study groups. The levels of vitamin D were also comparable (77 (64-91) vs. 74 (60-92) nmol/L, p = 0.50; median and interquartile range). A total of 38 (13%) and 43 (9.8%) subjects presented insufficient (&lt;50 nmol/L) levels of vitamin D (p = 0.42) during the current pandemic and in the CENERI study, respectively. These data do not support the hypothesis that during the SARS-CoV-2 pandemic, late adolescents are at higher risk of vitamin insufficiency