Effects of switch leakages upon Nimbus-7 SMMR calibration

A calibration model for the Nimbus 7 Scanning Multichannel Microwave Radiometer (SMMR) is studied. This model not only removes major drawbacks of the current calibration model but also helps in the understanding of the performance degradation of the aging instrument. The current Nimbus 7 SMMR calibration algorithm was derived without considering the interference effect between the two orthogonally polarized signals merging at a ferrite polarization selector switch. The resulting calibrated brightness temperatures, considered as a function of scan angle, are not symmetric around scan angle = 0. However, neither the origin of the asymmetry nor the manner in which the two orthogonal components are mixed has been fully understood. The new calibration model proposed incorporates all the leakage factors associated with the ferrite switches along the signal paths. The resulting calibration equations clarify how the orthogonal components of surface brightness are coupled at radiometers. As a consequence, the origin of the asymmetry is clearly identified and explained. In addition, the feasibility of absolute calibration using in-orbit data is discussed

Batalin-Tyutin Quantization of the Chiral Schwinger Model

We quantize the chiral Schwinger Model by using the Batalin-Tyutin formalism. We show that one can systematically construct the first class constraints and the desired involutive Hamiltonian, which naturally generates all secondary constraints. For $a>1$, this Hamiltonian gives the gauge invariant Lagrangian including the well-known Wess-Zumino terms, while for $a=1$ the corresponding Lagrangian has the additional new type of the Wess-Zumino terms, which are irrelevant to the gauge symmetry.Comment: 15 pages, latex, no figures, to be published in Z. Phys. C (1995

On the conditions for the existence of Perfect Learning and power law in learning from stochastic examples by Ising perceptrons

In a previous letter, we studied learning from stochastic examples by perceptrons with Ising weights in the framework of statistical mechanics. Under the one-step replica symmetry breaking ansatz, the behaviours of learning curves were classified according to some local property of the rules by which examples were drawn. Further, the conditions for the existence of the Perfect Learning together with other behaviors of the learning curves were given. In this paper, we give the detailed derivation about these results and further argument about the Perfect Learning together with extensive numerical calculations.Comment: 28 pages, 43 figures. Submitted to J. Phys.

A Multi-dimensional Code for Isothermal Magnetohydrodynamic Flows in Astrophysics

We present a multi-dimensional numerical code to solve isothermal magnetohydrodynamic (IMHD) equations for use in modeling astrophysical flows. First, we have built a one-dimensional code which is based on an explicit finite-difference method on an Eulerian grid, called the total variation diminishing (TVD) scheme. Recipes for building the one-dimensional IMHD code, including the normalized right and left eigenvectors of the IMHD Jacobian matrix, are presented. Then, we have extended the one-dimensional code to a multi-dimensional IMHD code through a Strang-type dimensional splitting. In the multi-dimensional code, an explicit cleaning step has been included to eliminate non-zero $\nabla\cdot B$ at every time step. To estimate the proformance of the code, one- and two-dimensional IMHD shock tube tests, and the decay test of a two-dimensional Alfv\'{e}n wave have been done. As an example of astrophysical applications, we have simulated the nonlinear evolution of the two-dimensional Parker instability under a uniform gravity.Comment: Accepted for publication in ApJ, using aaspp4.sty, 22 text pages with 10 figure

Lanczos exact diagonalization study of field-induced phase transition for Ising and Heisenberg antiferromagnets

Using an exact diagonalization treatment of Ising and Heisenberg model Hamiltonians, we study field-induced phase transition for two-dimensional antiferromagnets. For the system of Ising antiferromagnet the predicted field-induced phase transition is of first order, while for the system of Heisenberg antiferromagnet it is the second-order transition. We find from the exact diagonalization calculations that the second-order phase transition (metamagnetism) occurs through a spin-flop process as an intermediate step.Comment: 4 pages, 4 figure

Adjuvant chemotherapy and survival among patients 70 years of age and younger with node-negative breast cancer and the 21-gene recurrence score of 26-30

BACKGROUND: The benefits of chemotherapy in node-negative, hormone receptor-positive, and human epidermal growth factor receptor 2 (HER2)-negative breast cancer patients with the 21-gene recurrence score (RS) of 18-30, particularly those with RS 26-30, are not known. METHODS: Using the Surveillance, Epidemiology, and End Results (SEER) data, we retrospectively identified 29,137 breast cancer patients with the 21-gene RS of 18-30 diagnosed between 2004 and 2015. Mortality risks according to the RS and chemotherapy use were compared by the Kaplan-Meier method and Cox\u27s proportional hazards model. RESULTS: Among the breast cancer patients with the RS 18-30, 21% of them had RS 26-30. Compared to breast cancer patients with RS 18-25, patients with RS 26-30 had more aggressive tumor characteristics and chemotherapy use and increased risk of breast cancer-specific mortality and overall mortality. In breast cancer patients who were aged ≤ 70 years and had RS of 26-30, chemotherapy administration was associated with a 32% lower risk of breast cancer-specific mortality (hazard ratio [HR], 0.68; 95% confidence interval [CI], 0.47-0.99) and a 42% lower risk of overall mortality (HR, 0.58; 95% CI, 0.44-0.76). Survival benefits were most pronounced in breast cancer patients who were younger or had grade III tumor. CONCLUSIONS: The 21-gene RS of 18-30 showed heterogeneous outcomes, and the RS 26-30 was a significant prognostic factor for an increased risk of mortality. Adjuvant chemotherapy could improve the survival of node-negative, hormone receptor-positive, and HER2-negative breast cancer patients with the 21-gene RS 26-30 and should be considered for patients, especially younger patients or patients with high-grade tumors

Central Neurocytoma: A Review of Clinical Management and Histopathologic Features.

Central neurocytoma (CN) is a rare, benign brain tumor often located in the lateral ventricles. CN may cause obstructive hydrocephalus and manifest as signs of increased intracranial pressure. The goal of treatment for CN is a gross total resection (GTR), which often yields excellent prognosis with a very high rate of tumor control and survival. Adjuvant radiosurgery and radiotherapy may be considered to improve tumor control when GTR cannot be achieved. Chemotherapy is also not considered a primary treatment, but has been used as a salvage therapy. The radiological features of CN are indistinguishable from those of other brain tumors; therefore, many histological markers, such as synaptophysin, can be very useful for diagnosing CNs. Furthermore, the MIB-1 Labeling Index seems to be correlated with the prognosis of CN. We also discuss oncogenes associated with these elusive tumors. Further studies may improve our ability to accurately diagnose CNs and to design the optimal treatment regimens for patients with CNs

Successful live birth from vitrified oocytes after 5 years of cryopreservation

Abstract Objective To report a birth of a healthy boy after long-term cryopreservation of oocytes by vitrification. Design Clinical application. Setting IVF Center. Patient A 17 year-old female with secondary pulmonary hypertension caused by transposition of great vessels visited our center in 2002, and she wished oocytes cryopreservation to avoid possible sterility after the following category X medication treatment. Intervention(s) Vitrified oocytes on Electron Microscope (EM) grids were warmed after 5 years of storage. Surviving MII oocytes were microinjected for fertilization and two embryos were transferred into a gestational carrier day 5 after microinjection. Main Outcome Measure(s) Survival, fertilization, cleavage, clinical pregnancy and delivery. Result(s) Eleven out of fourteen oocytes (78.6%) survived warming. Eight Metaphase II (MII) oocytes and 3 in vitro matured oocytes were microinjected; all 11 oocytes (100%) fertilized and 2 embryos were transferred on day 5. A healthy baby boy weighing 3,600 g was delivered at 38 weeks of gestation. Live-birth rates per warmed oocyte and per injected oocyte were 7.1% and 9.1% respectively. Conclusion(s) Cryopreservation after vitrification with EM grids maintained the developmental competence of oocytes after long-term storage and resulted in a successful live birth. Keywords Human oocyte cryopreservation . Vitrification . Electron microscope grid . Ethylene glycol . Clinical outcome Since the first successful pregnancy from frozen human oocyte was reported 20 years ago [1], remarkable technological progress has been made in the area of cryopreservation of human oocytes. The recent increased interest in vitrification has resulted in improved efficiency and pregnancy outcomes Over the last decade, multiple clinics have reported IVF successes after transfer of embryos derived from frozen/ thawed oocytes Here, we report the healthy outcome of a now 2 year old boy who was born after vitrification of oocytes that were stored for 5 years. Capsule Documentation of a pregnancy after long-term storage of vitrified oocytes

Electrochemical properties of composite cathodes using Sm doped layered perovskite for intermediate temperature-operating solid oxide fuel cell

The authors are grateful for the support of the Basic Science Research Program, part of the National Research Foundation of Korea (NRF), funded by the Ministry of Science, ICT and Future Planning (No. 2014R1A1A1004163).SmBaCo2O5+d (SBCO) showed the lowest observed Area Specific Resistance (ASR) value in the LnBaCo2O5+d (Ln: Pr, Nd, Sm, and Gd) oxide system for the overall temperature ranges tested. The ASR of a composite cathode (mixture of SBCO and Ce0.9Gd0.1O2−d) on a Ce0.9Gd0.1O2−d (CGO91) electrolyte decreased with respect to the CGO91 content; the percolation limit was also achieved for a 50 wt% SBCO and 50 wt% CGO91 (SBCO50) composite cathode. The ASRs of SBCO50 on the dense CGO91 electrolyte in the overall temperature range of 500 to 750 °C were relatively lower than those of SBCO50 on the CGO91 coated dense 8 mol % yttria-stabilized zirconia (8YSZ) electrolyte for the same temperature range. From 750 °C and for all higher temperatures tested, however, the ASRs of SBCO50 on the CGO91 coated dense 8YSZ electrolyte were lower than those of the CGO91 electrolyte. The maximum power densities of SBCO50 on the Ni-8YSZ/8YSZ/CGO91 buffer layer were 1.034 W cm−2 and 0.611 W cm−2 at 800 °C and 700 °C.PostprintPeer reviewe