84 research outputs found
Signatures of X-ray reverberation in the power spectra of AGN
We compute fully relativistic disc response functions in the case of the
"lamp-post" geometry using the full observed reflection spectrum for various
X-ray source heights, disc inclination, and spin values of the central black
hole. Since the observed PSD is equal to the product of the intrinsic power
spectrum with the "transfer function" (i.e. the Fourier transform of the disc
response function), we are able to predict the observed PSDs in the case of
X-ray illumination of the inner disc. The observed PSD should show a prominent
dip at high frequencies and an oscillatory behaviour, with a decreasing
amplitude, at higher frequencies. The reverberation "echo" features should be
more prominent in energy bands where the reflection component is more
pronounced. The frequency of the dip is independent of energy, and it is mainly
determined by the black hole mass and the X-ray source height. The amplitude of
the dip increases with increasing black hole spin and inclination angle, as
long as the height of the "lamp" is smaller than ~10 gravitational radii. The
detection of the X-ray reverberation signals in the PSDs can provide further
evidence for X-ray illumination of the inner disc in AGN. Our results are
largely independent of the assumed geometry of the disc-corona system, as long
as it does not change with time, and the disc response function is
characterized by a sharp rise, a "plateau", and a decline at longer times.
Irrespective of the geometry, the frequency of the main dip should decrease
with increasing "mean time" of the response function, and the amplitude of the
dip should increase with increasing reflection fraction.Comment: Astronomy and Astrophysics accepte
QPO in RE J1034+396: model constraints from observed trends
We analyze the time variability of the X-ray emission of RE J1034+396, an
active galactic nucleus with the first firm detection of a quasi-periodic
oscillations (QPO). Based on the results of a wavelet analysis, we find a drift
in the QPO central frequency. The change inthe QPO frequency correlates with
the change in the X-ray flux with a short time delay. Linear structures such as
shocks, spiral waves, orvery distant flares seem to be a favored explanation
for this particular QPO event.Comment: to appear in the proceedings to "The Central Kiloparsec in Galactic
Nuclei (AHAR2011)", Journal of Physics: Conference Series (JPCS), IOP
Publishin
Transforming global leadership skills in graduate nursing programs using an intercultural setting and a case study on refugees.
Transformation of our world to a more just and equitable system will require a fundamental shift from a domination approach to a partnership-based approach. In nursing and health care, this shift will require a global perspective with culturally humble providers and systems. In this article we share the experience of our international course Leadership in Nursing – a Global Approach, a joint project of the University of Iceland Faculty of Nursing and the University of Minnesota School of Nursing. This collaborative immersion course offers a model of global partnership-based health-care education. International partnership-based collaboration in nursing and health-care education prepares students and faculty to take an active role in transforming global systems. Keywords: cultural humility; global leadership; nursing; partnershipPeer reviewe
Reductions in cardiovascular, cerebrovascular, and respiratory mortality following the national Irish smoking ban: Interrupted time-series analysis
Copyright @ 2013 Stallings-Smith et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.This article has been made available through the Brunel Open Access Publishing Fund.Background: Previous studies have shown decreases in cardiovascular mortality following the implementation of comprehensive smoking bans. It is not known whether cerebrovascular or respiratory mortality decreases post-ban. On March 29, 2004, the Republic of Ireland became the first country in the world to implement a national workplace smoking ban. The aim of this study was to assess the effect of this policy on all-cause and cause-specific, non-trauma mortality. Methods: A time-series epidemiologic assessment was conducted, utilizing Poisson regression to examine weekly age and gender-standardized rates for 215,878 non-trauma deaths in the Irish population, ages ≥35 years. The study period was from January 1, 2000, to December 31, 2007, with a post-ban follow-up of 3.75 years. All models were adjusted for time trend, season, influenza, and smoking prevalence. Results: Following ban implementation, an immediate 13% decrease in all-cause mortality (RR: 0.87; 95% CI: 0.76-0.99), a 26% reduction in ischemic heart disease (IHD) (RR: 0.74; 95% CI: 0.63-0.88), a 32% reduction in stroke (RR: 0.68; 95% CI: 0.54-0.85), and a 38% reduction in chronic obstructive pulmonary disease (COPD) (RR: 0.62; 95% CI: 0.46-0.83) mortality was observed. Post-ban reductions in IHD, stroke, and COPD mortalities were seen in ages ≥65 years, but not in ages 35-64 years. COPD mortality reductions were found only in females (RR: 0.47; 95% CI: 0.32-0.70). Post-ban annual trend reductions were not detected for any smoking-related causes of death. Unadjusted estimates indicate that 3,726 (95% CI: 2,305-4,629) smoking-related deaths were likely prevented post-ban. Mortality decreases were primarily due to reductions in passive smoking. Conclusions: The national Irish smoking ban was associated with immediate reductions in early mortality. Importantly, post-ban risk differences did not change with a longer follow-up period. This study corroborates previous evidence for cardiovascular causes, and is the first to demonstrate reductions in cerebrovascular and respiratory causes
Coordinated multi-wavelength observations of Sgr A*
We report on recent near-infrared (NIR) and X-ray observations of Sagittarius
A* (Sgr A*), the electromagnetic manifestation of the ~4x10^6 solar masses
super-massive black hole (SMBH) at the Galactic Center. The goal of these
coordinated multi-wavelength observations is to investigate the variable
emission from Sgr A* in order to obtain a better understanding of the
underlying physical processes in the accretion flow/outflow. The observations
have been carried out using the NACO adaptive optics (AO) instrument at the
European Southern Observatory's Very Large Telescope (July 2005, May 2007) and
the ACIS-I instrument aboard the Chandra X-ray Observatory (July 2005). We
report on a polarized NIR flare synchronous to a 8x1033 erg/s X-ray flare in
July 2005, and a further flare in May 2007 that shows the highest sub-flare to
flare contrast observed until now. The observations can be interpreted in the
framework of a model involving a temporary disk with a short jet. In the disk
component flux density variations can be explained due to hot spots on
relativistic orbits around the central SMBH. The variations of the
sub-structures of the May 2007 flare are interpreted as a variation of the hot
spot structure due to differential rotation within the disk.Comment: 15 pages, 7 figures, contribution for the conference "The Universe
under the Microscope" (AHAR 2008), to be published in Journal of Physics:
Conference Series by Institute of Physics Publishin
Targets for maintenance of dead wood for biodiversity conservation based on extinction thresholds
A randomized trial to assess the impact of opinion leader endorsed evidence summaries on the use of secondary prevention strategies in patients with coronary artery disease: the ESP-CAD trial protocol [NCT00175240]
BACKGROUND: Although numerous therapies have been shown to be beneficial in the prevention of myocardial infarction and/or death in patients with coronary disease, these therapies are under-used and this gap contributes to sub-optimal patient outcomes. To increase the uptake of proven efficacious therapies in patients with coronary disease, we designed a multifaceted quality improvement intervention employing patient-specific reminders delivered at the point-of-care, with one-page treatment guidelines endorsed by local opinion leaders ("Local Opinion Leader Statement"). This trial is designed to evaluate the impact of these Local Opinion Leader Statements on the practices of primary care physicians caring for patients with coronary disease. In order to isolate the effects of the messenger (the local opinion leader) from the message, we will also test an identical quality improvement intervention that is not signed by a local opinion leader ("Unsigned Evidence Statement") in this trial. METHODS: Randomized trial testing three different interventions in patients with coronary disease: (1) usual care versus (2) Local Opinion Leader Statement versus (3) Unsigned Evidence Statement. Patients diagnosed with coronary artery disease after cardiac catheterization (but without acute coronary syndromes) will be randomly allocated to one of the three interventions by cluster randomization (at the level of their primary care physician), if they are not on optimal statin therapy at baseline. The primary outcome is the proportion of patients demonstrating improvement in their statin management in the first six months post-catheterization. Secondary outcomes include examinations of the use of ACE inhibitors, anti-platelet agents, beta-blockers, non-statin lipid lowering drugs, and provision of smoking cessation advice in the first six months post-catheterization in the three treatment arms. Although randomization will be clustered at the level of the primary care physician, the design effect is anticipated to be negligible and the unit of analysis will be the patient. DISCUSSION: If either the Local Opinion Leader Statement or the Unsigned Evidence Statement improves secondary prevention in patients with coronary disease, they can be easily modified and applied in other communities and for other target conditions
The effects of acute exercise on subsequent cigarette smoking
The present study was conducted to examine the effects of acute aerobic exercise on smoking behavior. On alternate days, 10 healthy young smokers were subjected to half an hour of sustained high exercise (about 56% of maximum work capacity) or of low exercise (about 28% of maximum, simulating normal daytime activity). During the high-exercise condition, there were pronounced increases in physiological markers of physical activity such as mean work, heart rate, and lactic acid as well as elevations in circulating hormones (norepinephrine, epinephrine, and immunoreactive beta-endorphin and cortisol) known to be affected by vigorous exercise. Despite a trend toward decreased desire for cigarettes after the high exercise condition, there were no differences in plasma nicotine levels following the smoking of a usual-brand cigarette 35 min later. The sustained effects of the two exercise conditions were also similar: plasma cotinine levels 24 hr later (reflecting nicotine intake over the entire exercise day) revealed no significant differences between hight and low exercise.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/44810/1/10865_2004_Article_BF00846420.pd
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