Human anisakiasis transmitted by marine food products.

Seafood-transmitted parasitic diseases represent an emerging area of interest to the U.S. Food and Drug Administration. Human infections with marine parasites are generally the result of ingesting uncooked seafood products. Over 50 species of helminthic parasites are known to infect humans worldwide. Recently, the number of infections with one of these helminths, the juvenile stage of the marine nematode, Anisakis simplex, has increased in the United States. Raw fish dishes such as lomi lomi salmon and sashimi are known to transmit the parasite to unsuspecting citizens and the most frequently implicated fish in the transmission of this zoonotic disease is the Pacific salmon (Oncorhynchus spp.). The risk of infection from fishes caught in Hawaiian waters is slight; however, a juvenile Anisakis simplex infected one patient from either locally caught aku or ahi. We report 4 new cases, which brings the total number of known cases in Hawaii to 7. Five of the 7 cases were diagnosed and treated by means of an endoscope and biopsy forceps. Serological profiles are presented in several of these cases. One case represents the first known instance of reinfection; the initial infection occurred 2 years prior. The second infection gave an opportunity to compare the human response to a challenge infection and to investigate the validity of the "double hit" theory. Increased awareness by physicians to the clinical features of this disease is warranted. The zoonotic disease, anisakiasis, should be considered in patients presenting with intense abdominal pain, if these patients admit they have recently eaten raw or undercooked seafoods.AI 19968/AI/NIAID NIH HHS/United State

Network traffic analysis for threats detection in the Internet of Things

As the prevalence of the Internet of Things (IoT) continues to increase, cyber criminals are quick to exploit the security gaps that many devices are inherently designed with. Users cannot be expected to tackle this threat alone, and many current solutions available for network monitoring are simply not accessible or can be difficult to implement for the average user, which is a gap that needs to be addressed. This article presents an effective signature-based solution to monitor, analyze, and detect potentially malicious traffic for IoT ecosystems in the typical home network environment by utilizing passive network sniffing techniques and a cloud application to monitor anomalous activity. The proposed solution focuses on two attack and propagation vectors leveraged by the infamous Mirai botnet, namely DNS and Telnet. Experimental evaluation demonstrates the proposed solution can detect 98.35 percent of malicious DNS traffic and 99.33 percent of Telnet traffic for an overall detection accuracy of 98.84 percent

Outdoor performance of a thin-film gallium-arsenide photovoltaic module

We deployed a 855 cm2 thin-film, single-junction gallium arsenide (GaAs) photovoltaic (PV) module outdoors. Due to its fundamentally different cell technology compared to silicon (Si), the module responds differently to outdoor conditions. On average during the test, the GaAs module produced more power when its temperature was higher. We show that its maximum-power temperature coefficient, while actually negative, is several times smaller in magnitude than that of a Si module used for comparison. The positive correlation of power with temperature in GaAs is due to temperature-correlated changes in the incident spectrum. We show that a simple correction based on precipitable water vapor (PWV) brings the photocurrent temperature coefficient into agreement with that measured by other methods and predicted by theory. The low operating temperature and small temperature coefficient of GaAs give it an energy production advantage in warm weather

A Service-Oriented Approach for Sensing in the Internet of Things: Intelligent Transportation Systems and Privacy Use Cases

This paper presents a Sensing-as-a-Service run-time Service Oriented Architecture (SOA), called 3SOA, for the development of Internet of Things (IoT) applications. 3SOA aims to allow interoperability among various IoT platforms and support service-oriented modelling at high levels of abstraction where fundamental SOA theories and techniques are fully integrated into a practical software engineering approach. 3SOA abstracts the dependencies of the middleware programming model from the application logic. This abstraction allows the development efforts to focus on writing the application logic independently from hardware platforms, middleware, and languages in which applications are programmed. To achieve this result, IoT objects are treated as independent entities that may interact with each other using a well-defined message exchange sequence. Each object is defined by the services it provides and the coordination protocol it supports. Objects are then able to coordinate their resources to address the global objectives of the system. To practically validate our proposals, we demonstrate an intelligent transportation system and data privacy functional prototypes as proof of concepts. The use cases show that 3SOA and the presented abstraction language allow the amalgamation of macroprogramming and node-centric programming to develop real-time and efficient applications over IoT

Network Traffic Analysis for Threats Detection in the Internet of Things

As the prevalence of the Internet of Things (IoT) continues to increase, cyber criminals are quick to exploit the security gaps that many devices are inherently designed with. Whilst users can not be expected to tackle this threat alone, many current solutions available for network monitoring are simply not accessible or can be difficult to implement for the average user and is a gap that needs to be addressed. This paper presents an effective signature-based solution to monitor, analyse and detect potentially malicious traffic for IoT ecosystems in the typical home network environment by utilising passive network sniffing techniques and a cloud-application to monitor anomalous activity. The proposed solution focuses on two attack and propagation vectors leveraged by the infamous Mirai botnet, namely DNS and Telnet. Experimental evaluation demonstrates the proposed solution can detect 98.35% of malicious DNS traffic and 99.33% of Telnet traffic respectively; for an overall detection accuracy of 98.84%

Routine screening of emergency admissions at risk of chronic hepatitis (SEARCH) identifies and links hepatitis B cases to care

Background and Aims: Significant barriers exist with hepatitis B (HBV) case detection and effective linkage to care (LTC). The emergency department (ED) is a unique healthcare interaction where hepatitis screening and LTC could be achieved. We examined the efficacy and utility of automated ED HBV screening for Overseas Born (OB) patients. Methods: A novel-automated hepatitis screening service “SEARCH” (Screening Emergency Admissions at Risk of Chronic Hepatitis) was piloted at a metropolitan hospital. A retrospective and comparative analysis of hepatitis testing during the SEARCH pilot compared to a period of routine testing was conducted. Results: During the SEARCH pilot, 4778 OB patients were tested for HBV (86% of eligible patient presentations), compared with 1.9% of eligible patients during a control period of clinician-initiated testing. SEARCH detected 108 (2.3%) hepatitis B surface antigen positive patients including 20 (19%) in whom the diagnosis was new. Among 88 patients with known HBV, 57% were receiving medical care, 33% had become lost to follow-up and 10% had never received HBV care. Overall, 30/88 (34%) patients with known HBV were receiving complete guideline-based care prior to re-engagement via SEARCH. Following SEARCH, LTC was successful achieved in 48/58 (83%) unlinked patients and 19 patients were commenced on anti-viral therapy. New diagnoses of cirrhosis and hepatocellular carcinoma were made in five and one patient(s) respectively. Conclusions: Automated ED screening of OB patients is effective in HBV diagnosis, re-diagnosis and LTC. Prior to SEARCH, the majority of patients were not receiving guideline-based care

The gene for a novel epidermal antigen maps near the neurofibromatosis 1 gene

Recently the M17S1 gene, encoding an epidermal antigen thought to play a role in cell adhesion, was mapped to chromosome bands 17q11-q12, placing it in the vicinity of the gene for the genetic disorder neurofi-bromatosis 1 (NF1). The pleomorphic cutaneous lesions of NF1 and the precedent for other genes being embedded within the NF1 gene prompted us to investigate whether the M17S1 gene mapped near, or within, the NF1 gene. Genetic linkage analyses revealed that M17S1 was tightly linked to NF1 and mapped within the interval bounded by D17S58 and D17S54. Physical mapping of an M17S1 cDNA on somatic cell hybrids, yeast artificial chromosomes, and an NF1 patient with a deletion involving an entire NF1 allele demonstrated that M17S1 is located at least 180 kb centromeric to the NF1 gene. The distance between the genes suggests that M17S1 is unlikely to contribute to the NF1 phenotype since a gross chromosomal rearrangement would be required to disrupt expression of both genes.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/29816/1/0000162.pd

Flexible Dye-Sensitized Solar Cell Based on Vertical ZnO Nanowire Arrays

Flexible dye-sensitized solar cells are fabricated using vertically aligned ZnO nanowire arrays that are transferred onto ITO-coated poly(ethylene terephthalate) substrates using a simple peel-off process. The solar cells demonstrate an energy conversion efficiency of 0.44% with good bending tolerance. This technique paves a new route for building large-scale cost-effective flexible photovoltaic and optoelectronic devices

Versatile control of metal-assisted chemical etching for vertical silicon microwire arrays and their photovoltaic applications

A systematic study was conducted into the use of metal-assisted chemical etching (MacEtch) to fabricate vertical Si microwire arrays, with several models being studied for the efficient redox reaction of reactants with silicon through a metal catalyst by varying such parameters as the thickness and morphology of the metal film. By optimizing the MacEtch conditions, high-quality vertical Si microwires were successfully fabricated with lengths of up to 23.2 mu m, which, when applied in a solar cell, achieved a conversion efficiency of up to 13.0%. These solar cells also exhibited an open-circuit voltage of 547.7 mV, a short-circuit current density of 33.2 mA/cm(2), and a fill factor of 71.3% by virtue of the enhanced light absorption and effective carrier collection provided by the Si microwires. The use of MacEtch to fabricate high-quality Si microwires therefore presents a unique opportunity to develop cost-effective and highly efficient solar cells.open1

Study of the temperature distribution in Si nanowires under microscopic laser beam excitation

The use of laser beams as excitation sources for the characterization of semiconductor nanowires (NWs) is largely extended. Raman spectroscopy and photoluminescence (PL) are currently applied to the study of NWs. However, NWs are systems with poor thermal conductivity and poor heat dissipation, which result in unintentional heating under the excitation with a focused laser beam with microscopic size, as those usually used in microRaman and microPL experiments. On the other hand, the NWs have subwavelength diameter, which changes the optical absorption with respect to the absorption in bulk materials. Furthermore, the NW diameter is smaller than the laser beam spot, which means that the optical power absorbed by the NW depends on its position inside the laser beam spot. A detailed analysis of the interaction between a microscopic focused laser beam and semiconductor NWs is necessary for the understanding of the experiments involving laser beam excitation of NWs. We present in this work a numerical analysis of the thermal transport in Si NWs, where the heat source is the laser energy locally absorbed by the NW. This analysis takes account of the optical absorption, the thermal conductivity, the dimensions, diameter and length of the NWs, and the immersion medium. Both free standing and heat-sunk NWs are considered. Also, the temperature distribution in ensembles of NWs is discussed. This analysis intends to constitute a tool for the understanding of the thermal phenomena induced by laser beams in semiconductor NWs