Effect of maternal cold exposure and nutrient restriction on insulin-like growth factor sensitivity in adipose tissue of newborn sheep

Adipose tissue mass in the newborn is determined in part by insulin-like growth factor (IGF)s, which are dependent on the maternal nutritional and metabolic environment during late gestation. The present study was designed to determine whether maternal cold exposure (CE) commencing in mid gestation could modulate some of the adaptive effects of nutrient restriction in late gestation on adipose tissue endocrine sensitivity in the resulting offspring. Twenty eight pregnant sheep were entered into the study and were either shorn, i.e. cold exposed, from 70 days gestation (term = 147 days), or remained unshorn, and were fed either their total calculated metabolisable energy (ME) requirements for body weight and pregnancy from 110 days gestation or 50% of this amount (n=7 per group). Adipose tissue was sampled from the offspring at one day of age and the mRNA abundance for IGF-I, II their receptors (R) and GH secretagogue receptor-1a (GHSR-1a) were determined. CE mothers produced larger offspring with more perirenal adipose tissue, an adaptation prevented by maternal nutrient restriction. Nutrient restriction in unshorn mothers increased IGF-I and IIR mRNA abundance. The mRNA abundances for IGF-I, II and IIR in adipose tissue were reduced by CE, adaptations independent of maternal food intake, whereas CE plus nutrient restriction increased GHSR-1a mRNA. In conclusion, maternal nutrient restriction with or without CE has very different effects on IGF sensitivity of adipose tissue and may act to ensure adequate fat stores are present in the newborn in the face of very different maternal endocrine and metabolic environments

Epistemic decision theory applied to multiple-target tracking

A decision philosophy that seeks the avoidance of error by trading off belief of truth and value of information is applied to the problem of recognizing tracks from multiple targets (MTT). A successful MTT methodology should be robust in that its performance degrades gracefully as the conditions of the collection become less favorable to optimal operation. By stressing the avoidance, rather than the explicit minimization, of error, the authors obtain a decision rule for trajectory-data association that does not require the resolution of all conflicting hypotheses when the database does not contain sufficient information to do so reliably. This rule, coupled with a set-valued Kalman filter for trajectory estimation, results in a methodology that does not attempt to extract more information from the database than it contains

Turnover of grassland roots in mountain ecosystems revealed by their radiocarbon signature: role of temperature and management

Root turnover is an important carbon flux component in grassland ecosystems because it replenishes substantial parts of carbon lost from soil via heterotrophic respiration and leaching. Among the various methods to estimate root turnover, the root’s radiocarbon signature has rarely been applied to grassland soils previously, although the value of this approach is known from studies in forest soils. In this paper, we utilize the root’s radiocarbon signatures, at 25 plots, in mountain grasslands of the montane to alpine zone of Europe.We place the results in context of a global data base on root turnover and discuss driving factors. Root turnover rates were similar to those of a subsample of the global data, comprising a similar temperature range, but measured with different approaches, indicating that the radiocarbon method gives reliable, plausible and comparable results. Root turnover rates (0.06–1.0 y-1) scaled significantly and exponentially with mean annual temperatures. Root turnover rates indicated no trend with soil depth. The temperature sensitivity was significantly higher in mountain grassland, compared to the global data set, suggesting additional factors influencing root turnover. Information on management intensity from the 25 plots reveals that root turnover may be accelerated under intensive and moderate management compared to low intensity or semi-natural conditions. Because management intensity, in the studied ecosystems, co-varied with temperature, estimates on root turnover, based on mean annual temperature alone, may be biased. A greater recognition of management as a driver for root dynamics is warranted when effects of climatic change on belowground carbon dynamics are studied in mountain grasslands.KB received support from the Swiss National Science Foundation, project 200021-115891 (www.snf.ch). SM received support from the Swiss State Secretariat for Education and Research, project C07.0031 (www.sbfi.admin.ch). MTS received support from the Spanish Ministry of Science and Innovation, (project CAPAS, CGL2010-22378-C03- 01) (www.idi.mineco.gob.es)

Australian local governments and affordable housing: Challenges and possibilities

© The Author(s) 2019. For an increasing proportion of Australian households, the Australian dream of home ownership is no longer an option. Neoliberal housing policy and the financialisation of housing has resulted in a housing affordability crisis. Historically, Australian housing policy has afforded only a limited role to local government. This article analyses the results of a nation-wide survey of Australian local governments’ perceptions of housing affordability in their local government area, the possibilities for their meaningful intervention, the challenges they face, the role of councillors and councils’ perceptions of what levels of government should take responsibility for housing. Almost all of the respondents from Sydney and Melbourne councils were clear that there is a housing affordability crisis in their local government area. We apply a framework analysing housing policy in the context of neoliberalism and the related financialisation of housing in order to analyse the housing affordability crisis in Sydney and Melbourne. We conclude that in order to begin resolving the housing crisis in Australia’s two largest cities there has to be an increasing role for local government, a substantial increase in the building of social and affordable housing and a rollback of policies that encourage residential property speculation. JEL Codes: R31, R21

Rural local governance and housing: Local government as facilitator

Housing affordability is an issue that affects all Australians, including those living in rural communities. Local governments in rural Australia are the most visible level of government for communities, and they are best placed to see first-hand the social and economic pressures that are impacting their communities. In this research, we consider the changing role of non-metropolitan local governments with respect to housing, and what it tells us about the state of Australia’s federal system. We examine the findings of a national survey of local government before exploring the challenges of rural local governance and access to affordable housing. We then show how one rural council facilitates a range of activities to address housing challenges, and then compare its actions with those of its neighbours. Overall, we find it is not common for rural local governments to take a proactive approach to affordable housing, and we discuss the ways in which rural councils can take a leadership role in addressing local issues of housing affordability

Turning round the telescope. Centre-right parties and immigration and integration policy in Europe

This is an Author's Original Manuscript of 'Turning round the telescope. Centre-right parties and immigration and integration policy in Europe', whose final and definitive form, the Version of Record, has been published in the Journal of European Public Policy 15(3):315-330, 2008 [copyright Taylor & Francis], available online at: http://www.tandfonline.com/doi.org/10.1080/13501760701847341

Satisfaction with democracy and voter turnout

Numerous studies conclude that countries in which citizens express higher levels of satisfaction with democracy also tend to display higher levels of voter turnout in national elections. Yet it is difficult to draw causal inferences from this positive cross-sectional relationship, because democracies feature many historical, cultural, and institutional differences that are not easily controlled for in cross-sectional comparisons. We apply an alternative, temporal approach to this issue by asking the question: Are over-time declines (increases) in aggregate levels of satisfaction within democracies associated with increases (declines) in levels of voter turnout within these democracies? Our temporal analysis of this relationship in 12 democracies over the period 1976–2011 reveals a pattern that is the opposite of that suggested by previous cross-sectional studies: namely, we find that over-time increases in citizens’ satisfaction with democracy are associated with significant decreases in voter turnout in national elections in these countries. </jats:p

Political brand image: an investigation into the operationalisation of the external orientation of David Cameron’s Conservative brand

This paper seeks to address the limited understanding of how to operationalise the external brand image of a political brand. More specifically, this research critically assesses the transfer potential of the six variables of brand image by Bosch, Venter, Han and Boshoff to deconstruct the UK Conservative Party brand from the perspective of young people aged 18–24 years during the 2010 UK General Election campaign. This research demonstrates the applicability of the six variables otherwise known as the ‘brand image framework’ to the political environment. However, the application of the brand image framework in its original conceptualisation proved problematic. Many of the brand image variables were clarified, rearticulated and simplified to address the political context. This refined conceptualisation provided an in-depth understanding of how to investigate the political brand image of David Cameron’s Conservative Party. This study addresses the paucity of research that operationalises external brand image and provides practitioners and academics within and beyond the context of political branding a mechanism to understand the external orientation of brands. This research may also be used by political and non-political brands as a basis to explore external brand image and compare its consistency with internal brand identity