Effect of Hydro-Resistance Training on Bat Velocity

The purpose of this study was to determine the effect of hydro-resistance training on bat velocity during mimicked baseball swings in twenty-five female college students. Subjects were pre-tested for bat velocity and assigned to dry land (n = 8), water (n = 8), and control (n = 9) groups. The dry land group swung a 737 g (26 oz) Easton T1 Thunderstick baseball bat for three sets of 15 swings, three days per week, for eight weeks. The water group performed the swings in shoulder deep water. The dry land and water groups also participated in mandatory team general resistance training three days per week. The control group performed no bat swing or resistance-training regimens. Mean bat velocity was measured with an electronic eye-timing device. A 3 x 2 (Group x Time) ANOVA with repeated measures was used for statistical analysis, followed up with Tukey’s post hoc test. Bat velocity decreased significantly for the dry land and water groups (24.0 ± 3.6 m/s to 20.6 ± 4.1 m/s and 23.8 ± 3.5 to 18.8 ± 4.1 m/s, respectively). Bat velocity did not change for the control group (21.5 ± 3.0 m/s to 20.2 ± 2.1 m/s). We speculate that the decreased bat velocity in the dry land and water groups was caused by the mandatory team general resistance-training program

Characterization of the initial filamentation of a relativistic electron beam passing through a plasma

The linear instability that induces a relativistic electron beam passing through a return plasma current to filament transversely is often related to some filamentation mode with wave vector normal to the beam or confused with Weibel modes. We show that these modes may not be relevant in this matter and identify the most unstable mode on the two-stream/filamentation branch as the main trigger for filamentation. This sets both the characteristic transverse and longitudinal filamentation scales in the non-resistive initial stage.Comment: 4 page, 3 figures, to appear in PR

Activation of the Listeria monocytogenes Virulence Program by a Reducing Environment.

Upon entry into the host cell cytosol, the facultative intracellular pathogen Listeria monocytogenes coordinates the expression of numerous essential virulence factors by allosteric binding of glutathione (GSH) to the Crp-Fnr family transcriptional regulator PrfA. Here, we report that robust virulence gene expression can be recapitulated by growing bacteria in a synthetic medium containing GSH or other chemical reducing agents. Bacteria grown under these conditions were 45-fold more virulent in an acute murine infection model and conferred greater immunity to a subsequent lethal challenge than bacteria grown in conventional media. During cultivation in vitro, PrfA activation was completely dependent on the intracellular levels of GSH, as a glutathione synthase mutant (ΔgshF) was activated by exogenous GSH but not reducing agents. PrfA activation was repressed in a synthetic medium supplemented with oligopeptides, but the repression was relieved by stimulation of the stringent response. These data suggest that cytosolic L. monocytogenes interprets a combination of metabolic and redox cues as a signal to initiate robust virulence gene expression in vivoIMPORTANCE Intracellular pathogens are responsible for much of the worldwide morbidity and mortality from infectious diseases. These pathogens have evolved various strategies to proliferate within individual cells of the host and avoid the host immune response. Through cellular invasion or the use of specialized secretion machinery, all intracellular pathogens must access the host cell cytosol to establish their replicative niches. Determining how these pathogens sense and respond to the intracellular compartment to establish a successful infection is critical to our basic understanding of the pathogenesis of each organism and for the rational design of therapeutic interventions. Listeria monocytogenes is a model intracellular pathogen with robust in vitro and in vivo infection models. Studies of the host-sensing and downstream signaling mechanisms evolved by L. monocytogenes often describe themes of pathogenesis that are broadly applicable to less tractable pathogens. Here, we describe how bacteria use external redox states as a cue to activate virulence

Promoting Economic Development with Tourism in Rural Communities: Destination Image and Motivation to Return or Recommend

Improving tourism is one means Extension professionals and other community stakeholders can use to build rural economic resiliency. The research reported in this article evaluates what motivates tourists to visit and how they perceive of Wisconsin\u27s Kickapoo Valley as a destination. Data are drawn from surveys collected from out-of-town visitors. Results show the motivation to find excitement and adventure, the perception that the area is clean and hospitable, and whether visitors have been to the area more than once significantly affect their likelihood of returning to or recommending the area. Recommendations for how Extension professionals might use these findings are discussed

Slotted Rotatable Target Assembley and Systematic Error Analysis for a Search for Long Range Spin Dependent Interactions from Exotic Vector Boson Exchange Using Neutron Spin Rotation

We discuss the design and construction of a novel target array of nonmagnetic test masses used in a neutron polarimetry measurement made in search for new possible exotic spin dependent neutron–atominteractions of Nature at sub-mm length scales. This target was designed to accept and efficiently transmit a transversely polarized slow neutron beam through a series of long open parallel slots bounded by flat rectangular plates. These openings possessed equal atom density gradients normal to the slots from the flat test masses with dimensions optimized to achieve maximum sensitivity to an exotic spin-dependent interaction from vector boson exchanges with ranges in the mm - μm regime. The parallel slots were oriented differently in four quadrants that can be rotated about the neutron beam axis in discrete 90°increments using a Geneva drive. The spin rotation signals from the 4 quadrants were measured using a segmented neutron ion chamber to suppress possible systematic errors from stray magnetic fields in the target region. We discuss the per-neutron sensitivity of the target to the exotic interaction, the design constraints, the potential sources of systematic errors which could be present in this design, and our estimate of the achievable sensitivity using this method

Recirculating 1-K-Pot for Pulse-Tube Cryostats

A paper describes a 1-K-pot that works with a commercial pulse tube cooler for astrophysics instrumentation testbeds that require temperatures <1.7 K. Pumped liquid helium-4 cryostats were commonly used to achieve this temperature. However, liquid helium-4 cryostats are being replaced with cryostats using pulse tube coolers. The closed-cycle 1K-pot system for the pulse tube cooler requires a heat exchanger on the pulse tube, a flow restriction, pump-out line, and pump system that recirculates helium-4. The heat exchanger precools and liquefies helium- 4 gas at the 2.5 to 3.5 K pulse tube cold head. This closed-cycle 1-K-pot system was designed to work with commercially available laboratory pulse tube coolers. It was built using common laboratory equipment such as stainless steel tubing and a mechanical pump. The system is self-contained and requires only common wall power to operate. The lift of 15 mW at 1.1 K and base temperature of 0.97 K are provided continuously. The system can be scaled to higher heat lifts of .30 to 50 mW if desired. Ground-based telescopes could use this innovation to improve the efficiency of existing cry

The Forgotten Legacy of Bernard Mandeville

Bernard de Mandeville, an eighteenth century Dutch radical thinker, was widely condemned in his day for his views, but is important to us today because many of his ideas have had an influence on subsequent economic thought. Mandeville (1670-1733) was a precursor to Adam Smith, who has been clubbed the father of classical economics. Contrary to popular belief, it was Mandeville and not Smith who first described the seeming paradox that through individuals pursuing their own self-interests, the good of the public as a whole is increased. Also, Mandeville was one of the first proponents of free trade and specialization as keys to economic growth. To a more limited extent, Mandeville might also be considered a precursor to John Maynard Keynes, often referred to as the father of macroeconomics. Keynes concurred with Mandeville\u27s vision of the effect on the economy of too little consumption, i.e., too much savings. It is lamentable that despite these noteworthy contributions, to most people Mandeville remains an obscure figure in the evolution of economic thought. Although Mandeville published thirteen separate works, only the two most pertinent to his economic views will be discussed here. They are The Fable of the Bees: Or, Private Vices, Public Benefits and his Modest Defence of Publick Stews. Or, an Essay Upon Whoring as it is Now Practiced in These Kingdoms. The Fable of the Bees is Mandeville\u27s most well-known work and has received the most scholarly attention and criticism. The Fable grew out of an allegorical poem, The Grumbling Hive: Or, Knaves Turn\u27d Honest, which Mandeville published as a six-penny pamphlet in 1705. It remains today, as when it was written, quite controversial. Indeed, the book was declared a public nuisance by the grand jury of Middlesex in 1723

Thermodynamics of precision in quantum nanomachines

Fluctuations strongly affect the dynamics and functionality of nanoscale thermal machines. Recent developments in stochastic thermodynamics have shown that fluctuations in many far-from-equilibrium systems are constrained by the rate of entropy production via so-called thermodynamic uncertainty relations. These relations imply that increasing the reliability or precision of an engine's power output comes at a greater thermodynamic cost. Here we study the thermodynamics of precision for small thermal machines in the quantum regime. In particular, we derive exact relations between the power, power fluctuations, and entropy production rate for several models of few-qubit engines (both autonomous and cyclic) that perform work on a quantized load. Depending on the context, we find that quantum coherence can either help or hinder where power fluctuations are concerned. We discuss design principles for reducing such fluctuations in quantum nanomachines and propose an autonomous three-qubit engine whose power output for a given entropy production is more reliable than would be allowed by any classical Markovian model