5,938 research outputs found
Characterization of new hybrid pixel module concepts for the ATLAS Insertable B-Layer upgrade
The ATLAS Insertable B-Layer (IBL) collaboration plans to insert a fourth
pixel layer inside the present Pixel Detector to recover from eventual failures
in the current pixel system, especially the b-layer. Additionally the IBL will
ensure excellent tracking, vertexing and b-tagging performance during the LHC
phase I and add robustness in tracking with high luminosity pile-up. The
expected peak luminosity for IBL is 2 to 3centerdot1034 cm-2s-1 and IBL is
designed for an integrated luminosity of 700 fb-1. This corresponds to an
expected fluence of 5centerdot1015 1 MeV neqcm-2 and a total ionizing dose of
250 MRad. In order to cope with these requirements, two new module concepts are
under investigation, both based on a new front end IC, called FE-I4. This IC
was designed as readout chip for future ATLAS Pixel Detectors and its first
application will be the IBL. The planar pixel sensor (PPS) based module concept
benefits from its well understood design, which is kept as similar as possible
to the design of the current ATLAS Pixel Detector sensor. The second approach
of the new three dimensional (3D) silicon sensor technology benefits from the
shorter charge carrier drift distance to the electrodes, which completely
penetrate the sensor bulk. Prototype modules of both sensor concepts have been
build and tested in laboratory and test beam environment before and after
irradiation. Both concepts show very high performance even after irradiation to
5centerdot1015 1 MeV neqcm-2 and meet the IBL specifications in terms of hit
efficiency being larger than 97%. Lowest operational threshold studies have
been effected and prove independent of the used sensor concept the excellent
performance of FE-I4 based module concepts in terms of noise hit occupancy at
low thresholds.Comment: Part of 9th International Conference on Position Sensitive Detectors
(PSD9
The eclipsing post-common envelope binary CSS21055: a white dwarf with a probable brown-dwarf companion
We report photometric observations of the eclipsing close binary CSS21055
(SDSS J141126+200911) that strongly suggest that the companion to the
carbon-oxygen white dwarf is a brown dwarf with a mass between 0.030 and 0.074
Msun. The measured orbital period is 121.73min and the totality of the eclipse
lasts 125s. If confirmed, CSS21055 would be the first detached eclipsing WD+BD
binary. Spectroscopy in the eclipse could provide information about the
companion's evolutionary state and atmospheric structure.Comment: 6 pages, 5 figure
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Acceptance and commitment therapy as an adjunct to the MOVE! programme: a randomized controlled trial.
ObjectiveThe current study tested the efficacy of an acceptance and commitment therapy (ACT) group intervention for disinhibited eating behaviour as an adjunct to the Veterans Affairs MOVE!© weight management programme.MethodsVeterans (N = 88) with overweight or obesity who completed the MOVE! weight management programme and self-identified as having problems with 'stress-related eating' were randomized to four 2-h weekly ACT sessions or a continued behavioural weight-loss (BWL) intervention. Assessments were completed at baseline, post-treatment and 3- and 6-month follow-up on outcomes of interest including measures of disinhibited eating patterns, obesity-related quality of life, weight-related experiential avoidance and weight.ResultsThe BWL group exhibited significantly greater reductions in binge eating behaviour at post-treatment compared with the ACT group. Significant improvements in other outcomes were found with minimal differences between groups. In both groups, decreases in weight-related experiential avoidance were related to improvements in binge eating behaviour.ConclusionsTaken together, the continued BWL intervention resulted in larger improvements in binge eating behaviour than the ACT intervention. The two groups showed similar improvements in other disinhibited eating outcomes. Future studies are encouraged to determine if more integrated or longer duration of ACT treatment may maximize eating outcomes in MOVE.Trial Registration Number: This trial was registered with ClinicalTrials.gov database (NCT01757847)
Stationary Josephson effect in a weak-link between nonunitary triplet superconductors
A stationary Josephson effect in a weak-link between misorientated nonunitary
triplet superconductors is investigated theoretically. The non-self-consistent
quasiclassical Eilenberger equation for this system has been solved
analytically. As an application of this analytical calculation, the
current-phase diagrams are plotted for the junction between two nonunitary
bipolar wave superconducting banks. A spontaneous current parallel to the
interface between superconductors has been observed. Also, the effect of
misorientation between crystals on the Josephson and spontaneous currents is
studied. Such experimental investigations of the current-phase diagrams can be
used to test the pairing symmetry in the above-mentioned superconductors.Comment: 6 pages and 6 figure
Quantum whistling in superfluid 4He
Fundamental considerations predict that macroscopic quantum systems such as
superfluids and the electrons in superconductors will exhibit oscillatory
motion when pushed through a small constriction. Here we report the observation
of these oscillations between two reservoirs of superfluid 4He partitioned by
an array of nanometer-sized apertures. They obey the Josephson frequency
equation and are coherent amongst all the apertures. This discovery at the
relatively high temperature of 2K (2000 times higher than related phenomena in
3He) may pave the way for a new class of practical rotation sensors of
unprecedented precision.Comment: 6 pages, 3 figures, to be published in Natur
Photoassociation of cold atoms with chirped laser pulses: time-dependent calculations and analysis of the adiabatic transfer within a two-state model
This theoretical paper presents numerical calculations for photoassociation
of ultracold cesium atoms with a chirped laser pulse and detailed analysis of
the results. In contrast with earlier work, the initial state is represented by
a stationary continuum wavefunction. In the chosen example, it is shown that an
important population transfer is achieved to vibrational levels in
the vicinity of the v=98 bound level in the external well of the
potential. Such levels lie in the energy range swept by
the instantaneous frequency of the pulse, thus defining a ``photoassociation
window''. Levels outside this window may be significantly excited during the
pulse, but no population remains there after the pulse. Finally, the population
transfer to the last vibrational levels of the ground (6s + 6s)
is significant, making stable molecules. The results are interpreted in the
framework of a two state model as an adiabatic inversion mechanism, efficient
only within the photoassociation window. The large value found for the
photoassociation rate suggests promising applications. The present chirp has
been designed in view of creating a vibrational wavepacket in the excited state
which is focussing at the barrier of the double well potential.Comment: 49 pages, 9 figures, submitted to Phys. Rev.
The role of fan benefits in shaping responses to sponsorship activation
As sponsorship in sports, arts and entertainment has grown, so have the myriad ways to activate partnerships. This study investigates the mechanisms through which sales-oriented activation campaigns affect consumer evaluations. Based on a benefit typology derived from real-world sponsorship activations, a conceptual framework is developed that links financial, symbolic and social benefit dimensions to consumer inferred activation motives and subsequent sponsor outcomes. An experimental field study of 1356 soccer fans employing three activation scenarios and a control group tests the framework. Results of a structural equation model show that altruistic motives are key in determining sponsorship outcomes, and that activation campaigns designed for symbolic or social benefits are most effective in inducing inference of altruistic motives
Genotoxic mixtures and dissimilar action: Concepts for prediction and assessment
This article has been made available through the Brunel Open Access Publishing Fund. This article is distributed under the terms of the
creative commons Attribution license which permits any use, distribution, and reproduction in any medium, provided the original author(s)and the source are credited.Combinations of genotoxic agents have frequently been assessed without clear assumptions regarding their expected (additive) mixture effects, often leading to claims of synergisms that might in fact be compatible with additivity. We have shown earlier that the combined effects of chemicals, which induce micronuclei (MN) in the cytokinesis-block micronucleus assay in Chinese hamster ovary-K1 cells by a similar mechanism, were additive according to the concept of concentration addition (CA). Here, we extended these studies and investigated for the first time whether valid additivity expectations can be formulated for MN-inducing chemicals that operate through a variety of mechanisms, including aneugens and clastogens (DNA cross-linkers, topoisomerase II inhibitors, minor groove binders). We expected that their effects should follow the additivity principles of independent action (IA). With two mixtures, one composed of various aneugens (colchicine, flubendazole, vinblastine sulphate, griseofulvin, paclitaxel), and another composed of aneugens and clastogens (flubendazole, doxorubicin, etoposide, melphalan and mitomycin C), we observed mixture effects that fell between the additivity predictions derived from CA and IA. We achieved better agreement between observation and prediction by grouping the chemicals into common assessment groups and using hybrid CA/IA prediction models. The combined effects of four dissimilarly acting compounds (flubendazole, paclitaxel, doxorubicin and melphalan) also fell within CA and IA. Two binary mixtures (flubendazole/paclitaxel and flubendazole/doxorubicin) showed effects in reasonable agreement with IA additivity. Our studies provide a systematic basis for the investigation of mixtures that affect endpoints of relevance to genotoxicity and show that their effects are largely additive.UK Food Standards Agenc
Allowing Visitors Back in the Nursing Home During the COVID-19 Crisis:A Dutch National Study Into First Experiences and Impact on Well-Being
Objectives: To prevent and control COVID-19 infections, nursing homes across the world have taken very restrictive measures, including a ban for visitors. These restrictive measures have an enormous impact on residents' well-being and pose dilemmas for staff, although primary data are lacking. A Dutch guideline was developed to cautiously open nursing homes for visitors during the COVID-19 pandemic. This study reports the first findings on how the guideline was applied in the local context; the compliance to local protocols; and the impact on well-being of residents, their family caregivers, and staff.Design: A mixed-methods cross-sectional study was conducted.Setting and Participants: In total, 26 nursing homes were permitted to enlarge their possibilities for allowing visitors in their facility. These nursing homes were proportionally representative of the Netherlands as they were selected by their local Area Health Authority for participation. At each nursing home, a contact person was selected for participation in the current study.Methods: A mixed-methods cross-sectional study was conducted, consisting of questionnaire, telephone interviews, analyses of documentation (ie, local visiting protocols), and a WhatsApp group.Results: Variation in local protocols was observed, for example, related to the use of personal protective equipment, location, and supervision of visits. In general, experiences were very positive. All nursing homes recognized the added value of real and personal contact between residents and their loved ones and indicated a positive impact on well-being. Compliance with local guidelines was sufficient to good. No new COVID-19 infections were reported during this time.Conclusions and Implications: These results indicate the value of family visitation in nursing homes and positive impact of visits. Based on these results, the Dutch government has decided to allow all nursing homes in the Netherlands to cautiously open their homes using the guidelines. More research is needed on impact and long-term compliance. (C) 2020 AMDA - The Society for Post-Acute and Long-Term Care Medicine.</p
Preliminary definitions for the sonographic features of synovitis in children
Objectives Musculoskeletal ultrasonography (US) has the potential to be an important tool in the assessment of disease activity in childhood arthritides. To assess pathology, clear definitions for synovitis need to be developed first. The aim of this study was to develop and validate these definitions through an international consensus process. Methods The decision on which US techniques to use, the components to be included in the definitions as well as the final wording were developed by 31 ultrasound experts in a consensus process. A Likert scale of 1-5 with 1 indicating complete disagreement and 5 complete agreement was used. A minimum of 80% of the experts scoring 4 or 5 was required for final approval. The definitions were then validated on 120 standardized US images of the wrist, MCP and tibiotalar joints displaying various degrees of synovitis at various ages. Results B-Mode and Doppler should be used for assessing synovitis in children. A US definition of the various components (i.e. synovial hypertrophy, effusion and Doppler signal within the synovium) was developed. The definition was validated on still images with a median of 89% (range 80-100) of participants scoring it as 4 or 5 on a Likert scale. Conclusions US definitions of synovitis and its elementary components covering the entire pediatric age range were successfully developed through a Delphi process and validated in a web-based still images exercise. These results provide the basis for the standardized US assessment of synovitis in clinical practice and research
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