The gamma-ray burst monitor for Lobster-ISS

Lobster-ISS is an X-ray all-sky monitor experiment selected by ESA two years ago for a Phase A study (now almost completed) for a future flight (2009) aboard the Columbus Exposed Payload Facility of the International Space Station. The main instrument, based on MCP optics with Lobster-eye geometry, has an energy passband from 0.1 to 3.5 keV, an unprecedented daily sensitivity of 2x10^{-12} erg cm^{-2}s$^{-1}, and it is capable to scan, during each orbit, the entire sky with an angular resolution of 4--6 arcmin. This X-ray telescope is flanked by a Gamma Ray Burst Monitor, with the minimum requirement of recognizing true GRBs from other transient events. In this paper we describe the GRBM. In addition to the minimum requirement, the instrument proposed is capable to roughly localize GRBs which occur in the Lobster FOV (162x22.5 degrees) and to significantly extend the scientific capabilities of the main instrument for the study of GRBs and X-ray transients. The combination of the two instruments will allow an unprecedented spectral coverage (from 0.1 up to 300/700 keV) for a sensitive study of the GRB prompt emission in the passband where GRBs and X-Ray Flashes emit most of their energy. The low-energy spectral band (0.1-10 keV) is of key importance for the study of the GRB environment and the search of transient absorption and emission features from GRBs, both goals being crucial for unveiling the GRB phenomenon. The entire energy band of Lobster-ISS is not covered by either the Swift satellite or other GRB missions foreseen in the next decade.Comment: 6 pages, 4 figures. Paper presented at the COSPAR 2004 General Assembly (Paris), accepted for publication in Advances in Space Research in June 2005 and available on-line at the Journal site (http://www.sciencedirect.com/science/journal/02731177), section "Articles in press

Quantum Brachistochrone for Mixed States

We present a general formalism based on the variational principle for finding the time-optimal quantum evolution of mixed states governed by a master equation, when the Hamiltonian and the Lindblad operators are subject to certain constraints. The problem reduces to solving first a fundamental equation (the {\it quantum brachistochrone}) for the Hamiltonian, which can be written down once the constraints are specified, and then solving the constraints and the master equation for the Lindblad and the density operators. As an application of our formalism, we study a simple one-qubit model where the optimal Lindblad operators control decoherence and can be simulated by a tunable coupling with an ancillary qubit. It is found that the evolution through mixed states can be more efficient than the unitary evolution between given pure states. We also discuss the mixed state evolution as a finite time unitary evolution of the system plus an environment followed by a single measurement. For the simplest choice of the constraints, the optimal duration time for the evolution is an exponentially decreasing function of the environment's degrees of freedom.Comment: 8 pages, 3 figure

Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA)

Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients. The cornerstones in the management of complicated IAIs are timely effective source control with appropriate antimicrobial therapy. Empiric antimicrobial therapy is important in the management of intra-abdominal infections and must be broad enough to cover all likely organisms because inappropriate initial antimicrobial therapy is associated with poor patient outcomes and the development of bacterial resistance. The overuse of antimicrobials is widely accepted as a major driver of some emerging infections (such as C. difficile), the selection of resistant pathogens in individual patients, and for the continued development of antimicrobial resistance globally. The growing emergence of multi-drug resistant organisms and the limited development of new agents available to counteract them have caused an impending crisis with alarming implications, especially with regards to Gram-negative bacteria. An international task force from 79 different countries has joined this project by sharing a document on the rational use of antimicrobials for patients with IAIs. The project has been termed AGORA (Antimicrobials: A Global Alliance for Optimizing their Rational Use in Intra-Abdominal Infections). The authors hope that AGORA, involving many of the world's leading experts, can actively raise awareness in health workers and can improve prescribing behavior in treating IAIs

T-T-T-That\u27s All, Folks!

The May 1996 Word Ways described the results of a National Public Radio competition of December 1995 in which listeners were challenged to write grammatical and understandable sentences containing the same word four or more times in succession. Some of the most interesting entries were based on repeated thats; this article summarizes them. Four thats is relatively easy, as achieved by the following strategy

CSM analyses of e+e−→ttˉH,ttˉZ,tbˉWe^+e^- \to t\bar t H, t\bar t Z, t\bar b W

We study the modifications of the amplitudes and cross sections of several processes, especially $e^+e^- \to t\bar t H, t\bar t Z, t\bar b W$, generated by Higgs boson and top quark compositeness, in particular within the CSM concept. We illustrate the observable differences that may appear between various, CSM conserving or CSM violating, compositeness possibilities.Comment: 13 pages, 4 figure

Widening the Nexus: From T-R to T-T-R

Higher education institutions are operating with scarce resources in a complex environment, and subject to various, often competing or changing demands. The integration of teaching, research and third stream activities within a coherent academic framework provides an opportunity to manage and exploit the positive relationships between these activities. This approach may also help to ease some of the tensions and 'fault lines' that currently beset academic life