Women's psychological Problems in Akananuru

Psychology is an attempt to learn about the behavior of all living things. Especially the personal quest to know oneself, pertaining to one's feelings, thoughts and actions. Psychology is the science of behavior and it's types. Self-contradictory coherence and social harmony are dual components of psychological well-being. Deficiency in any of these causes feelings of internal troubles, internal struggle, and internal tension. Such struggles and problems are revealed in the sangam literary songs. The aim of the study is to explore the psychological problems of women in Akananuru

Study of Post-Modernism and Post-Structuralism

Post- Modernism was not the invention of literary critics, but literature can certainly claim to be one of the most important laboratories of postmodernism. Literary postmodernism has tended to be focused on one kind of writing, namely, narrative fiction. It seems oddly fitting that what Hutcheon says “poetics of postmodernism” should turn out to be most in evidence in its fiction. One might almost say that the move from modernism to postmodernism involves a move from poetry to fiction. Modernism had also been characterized by efforts to establish the dignity and seriousness of the novel by developing for it a kind of poetics, centered on principles of structure. This poetics operated according to the principles of a scenography

ISOLATION OF TAXOL PRODUCING FUSICOCCUM SPECIES FROM CURRY LEAF AND ITS RANDOM AMPLIFIED POLYMORPHIC DNA ANALYSIS

ABSTRACTObjective: The potential compound of taxol has been used treatment of cancer in the medical field. This study is focused on the extraction of taxolfrom Fusicoccum sp.Methods: The pathogenic strain was grown in MID medium for the taxol production and extracted from the Fusicoccum culture filtrate and processedto the ultraviolet (UV)-spectroscopy analysis as well as infrared (IR) spectra analysis was done, and the sample was performed to the high-performancecolumn chromatography and further processed to the random amplified polymorphic DNA (RAPD) analysis of specific primer is PGFO1, PGFO2 areperformed.Results: UV-visible spectral analysis showed maximum value for 273 nm. The result of IR-spectrum analysis to find out the functional groups presentin sample and characteristic peak to conform the existences of OH group. The presence of taxol was confirmed using column chromatography.An analysis of taxol production was on the external standard of authentic taxol. The column chromatography process shows the amount of taxolproduction by Fusicoccum spp. 325 µg/L. RAPD analysis indicates the genetic relation among all isolates of fungus was analyzed by two randomprimers PGF01 and PGF02.Conclusion: The present investigation revealed that the taxol production from biological source was a significant effect, and the presence of taxolamount is analysis in Fusicoccum sp. 325 µg/L. The RAPD analysis of genetic stability of in vitro grown fungus and genotypic with two differentprimers shows that five fungus species with corresponding primer efficiency was amplified.Keywords: Taxol production, Fusicoccum sp., Ultraviolet-spectroscopy, Infrared, Spectrum analysis, Scanning electron microscopy

Nanotechnology and Protective Clothing for Defence Personnel

Defence personnel face multiple threats from different quarters, like terrorist groups and rogue nations, who own not only advanced lethal weapons but also chemical and biological warfare weapons. The present day protective clothing system used by the defence sector is vulnerable to modern weapons and also have some inherent weaknesses like high cost, bulkiness and discomfort in wearing. Nanotechnology- based materials offer a promising future in this areadue to their extraordinary physical, chemical, mechanical, and electrical properties at nano-level.This paper outlines the various developments related to the application of nanotechnology inproducing lightweight and comfortable protective clothing for the military personnel and also some new developments like sensor, energy storage, conductivity, and decontaminant fabrics.Defence Science Journal, 2008, 58(4), pp.451-459, DOI:http://dx.doi.org/10.14429/dsj.58.166

Enhancing herbicides sorption in sodic soils through biochar amendment : A promising approach for sustainable agriculture

This study is essential for assessing the binding capacity of Prosopis wood biochar to commonly used herbicides, Pretilachlor and Pendimethalin. Understanding their sorption dynamics at varying biochar application rates and exposure times is crucial for sustainable and effective herbicide management in intensively farming agricultural fields and for reducing environmental contamination. The Prosopis wood biochar was produced in an earthen kiln at 300-350°C. The batch experiment was conducted to study the sorption potential of biochar additions at rates of 0, 5, and 10 t ha-1. The herbicides were added to the homogenized soil-biochar mixes at zero, whole, twice, and four times the recommended dose. The sorption of the herbicides by soil biochar mixture was studied for 12 and 24 hours. The result showed that Pendimethalin sorption increased with biochar application rate, requiring 24 hours for 95% sorption at 4X dose without biochar (77.95 mg/kg soil) and 12 hours with 10 t/ha biochar (75.82 mg/kg soil). The Kd value increased with biochar application (0.57-77.95 mg/kg soil) and decreased with pendimethalin application (77.95-3.04 mg/kg soil). Maximum sorption (95%) was attained within 12 hours for 1X and 2X rates and 24 hours for 4X rates when biochar was added. This demonstrated that although pendimethalin residue in the soil can be immobilized by adding biochar within 8 hours at lower rates, more than 24 hours were required when pendimethalin was applied at higher rates or repeatedly. Biochar can be used to reduce pendimethalin leaching in agricultural fields, especially sodic soils, at higher application rates.

A comparison of the effects of physical and chemical mutagens in sesame (Sesamum indicum L.)

Three sesame genotypes (Rama, SI 1666 and IC 21706) were treated with physical (γ-rays: 200 Gy, 400 Gy or 600 Gy) or chemical (ethyl methane sulphonate, EMS: 0.5%, 1.0%, 1.5% or 2.0%) mutagens and their mutagenic effectiveness and efficiency were estimated in the M 2 generation. The M 3 generation was used to identify the most effective mutagen and dose for induction of mutations. The average effectiveness of EMS was much higher than γ-rays. The lowest dose of γ-rays (200 Gy) and the lowest concentration of EMS (0.5%) showed the highest mutagenic efficiency in all genotypes. Analysis of the M 3 generation data based on parameters such as the variance ratio and the difference in residual variances derived from the model of Montalván and Ando indicated that 0.5% concentration of EMS was the most effective treatment for inducing mutations

Rapid and Accurate Prediction and Scoring of Water Molecules in Protein Binding Sites

Water plays a critical role in ligand-protein interactions. However, it is still challenging to predict accurately not only where water molecules prefer to bind, but also which of those water molecules might be displaceable. The latter is often seen as a route to optimizing affinity of potential drug candidates. Using a protocol we call WaterDock, we show that the freely available AutoDock Vina tool can be used to predict accurately the binding sites of water molecules. WaterDock was validated using data from X-ray crystallography, neutron diffraction and molecular dynamics simulations and correctly predicted 97% of the water molecules in the test set. In addition, we combined data-mining, heuristic and machine learning techniques to develop probabilistic water molecule classifiers. When applied to WaterDock predictions in the Astex Diverse Set of protein ligand complexes, we could identify whether a water molecule was conserved or displaced to an accuracy of 75%. A second model predicted whether water molecules were displaced by polar groups or by non-polar groups to an accuracy of 80%. These results should prove useful for anyone wishing to undertake rational design of new compounds where the displacement of water molecules is being considered as a route to improved affinity

Structure-Based Virtual Screening for Drug Discovery: a Problem-Centric Review

Structure-based virtual screening (SBVS) has been widely applied in early-stage drug discovery. From a problem-centric perspective, we reviewed the recent advances and applications in SBVS with a special focus on docking-based virtual screening. We emphasized the researchers’ practical efforts in real projects by understanding the ligand-target binding interactions as a premise. We also highlighted the recent progress in developing target-biased scoring functions by optimizing current generic scoring functions toward certain target classes, as well as in developing novel ones by means of machine learning techniques

Cotton in the new millennium: advances, economics, perceptions and problems

Cotton is the most significant natural fibre and has been a preferred choice of the textile industry and consumers since the industrial revolution began. The share of man-made fibres, both regenerated and synthetic fibres, has grown considerably in recent times but cotton production has also been on the rise and accounts for about half of the fibres used for apparel and textile goods. To cotton’s advantage, the premium attached to the presence of cotton fibre and the general positive consumer perception is well established, however, compared to commodity man-made fibres and high performance fibres, cotton has limitations in terms of its mechanical properties but can help to overcome moisture management issues that arise with performance apparel during active wear. This issue of Textile Progress aims to: i. Report on advances in cotton cultivation and processing as well as improvements to conventional cotton cultivation and ginning. The processing of cotton in the textile industry from fibre to finished fabric, cotton and its blends, and their applications in technical textiles are also covered. ii. Explore the economic impact of cotton in different parts of the world including an overview of global cotton trade. iii. Examine the environmental perception of cotton fibre and efforts in organic and genetically-modified (GM) cotton production. The topic of naturally-coloured cotton, post-consumer waste is covered and the environmental impacts of cotton cultivation and processing are discussed. Hazardous effects of cultivation, such as the extensive use of pesticides, insecticides and irrigation with fresh water, and consequences of the use of GM cotton and cotton fibres in general on the climate are summarised and the effects of cotton processing on workers are addressed. The potential hazards during cotton cultivation, processing and use are also included. iv. Examine how the properties of cotton textiles can be enhanced, for example, by improving wrinkle recovery and reducing the flammability of cotton fibre