Social and Behavior Change Communication Interventions Delivered Face-to-Face and by a Mobile Phone to Strengthen Vaccination Uptake and Improve Child Health in Rural India: Randomized Pilot Study

Background: In resource-poor settings, lack of awareness and low demand for services constitute important barriers to expanding the coverage of effective interventions. In India, child

Structural and dielectric characterization of sputtered Tantalum Titanium Oxide thin films for high temperature capacitor applications

International audienc

MRI cine-tagging of cardiac-induced motion for noninvasive staging of liver fibrosis

Background MR elastography is a noninvasive technique that provides high diagnostic accuracy for the staging of liver fibrosis; however, it requires external hardware and mainly assesses the right lobe. Purpose To evaluate the diagnostic performance of MRI cine-tagging for staging fibrosis in the left liver lobe, using biopsy as the reference standard. Study Type Institutional Review Board (IRB)-approved two-center prospective study. Population Seventy-six patients with chronic liver disease who underwent an MRI cine-tagging examination and a liver biopsy within a 6-week interval. Field Strength/Sequence 2D-GRE multislice sequence at 3.0T with spatial modulation of the magnetization preparation sequence and peripheral pulse-wave triggering on two coronal slices chosen underneath the heart apex to capture maximal deformation with consecutive breath-holds adapted to patient cardiac frequency. Assessment A region of interest was selected in the liver close to the heart apex. Maximal strain was evaluated with the harmonic phase (HARP) technique. Statistical Tests Spearman's correlation, Kruskal-Wallis test, Mann-Whitney U-test, and receiver operating characteristic (ROC) analysis were performed. Results Liver strain measured on tagged images decreased with higher histological fibrosis stage (rho = -0.68, P = F1, 0.84 (0.76-0.93) for stages = F2, 0.86 (0.78-0.94) for stages = F3, and 0.87 (0.77-0.96) for stages <= F3 vs. F4. Data Conclusion MRI cine-tagging is a promising technique for measuring liver strain without additional elastography hardware. It could be used to assess the left liver lobe as a complement to current techniques assessing the right lobe. Technical Efficacy: 3 J. Magn. Reson. Imaging 2019.Cardiovascular Aspects of Radiolog