386 research outputs found

    Modelling Esker Formation on Mars

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    International audience<p><strong>Introduction:</strong>  Eskers are sinuous sedimentary ridges that are widespread across formerly glaciated landscapes on Earth. They form when sediment in subglacial tunnels is deposited by meltwater. Some sinuous ridges on Mars have been identified as eskers; whilst some are thought to have formed early in Mars’ history beneath extensive ice sheets, smaller, younger systems associated with extant glaciers in Mars’ mid latitudes have also been identified. Elevated geothermal heating and formation during periods with more extensive glaciation have been suggested as possible prerequisites for recent Martian esker deposition.</p><p>Here, we adapt a model of esker formation with g and other constants altered to Martian values, using it initially to investigate the impact of Martian conditions on subglacial tunnel systems, before investigating the effect of varying water discharge on esker deposition.</p><p><strong>Methods:</strong> To investigate the effect of these values on the operation of subglacial tunnel systems we first conduct a series of model experiments with steady water discharge, varying the assumed liquid density (r<sub>w</sub>) from 1000 kgm<sup>-3</sup> to 1980 kgm<sup>-3</sup> (the density of saturated perchlorate brine) and ice hardness (A) from 2.4x10<sup>-24</sup> Pa<sup>-3</sup>s<sup>-1</sup> to 5x10<sup>-27</sup> Pa<sup>-3</sup>s<sup>-1</sup> (a temperature range of 0°C to -50°C). We then investigate the impact of variable water discharge on esker formation to simulate very simply a possible release of meltwater from an assumed geothermal event beneath a Martian glacier or ice cap.</p><p><strong>Results and Discussion:</strong>  A key aspect of model behaviour is the decrease in sediment carrying capacity towards the ice margin due to increased tunnel size as ice thins. Our results suggest that Martian parameters emphasise this effect, making deposition more likely over a greater length of the conduit. Lower gravity has the largest impact; it reduces the modeled closure rate of subglacial tunnels markedly as this varies with overburden stress (and hence g) cubed. Frictional heating from flowing water also drops, but much less sensitively. Thus, for a given discharge, the tunnels tend to be larger, leading to lower water pressure and a reduction in flow power. This effect is amplified for harder ice. Higher inferred fluid density raises the flow power, but by a smaller amount.</p><p>These effects are clearly seen in the variable discharge experiments. Sediment is deposited on the falling limb of the hydrograph, when the tunnels are larger than the equivalent steady-state water discharge would produce. Sediment deposition occurs much further upglacier from the glacier snout, and occurs earlier on the falling limb leading to longer periods in which deposition occurs.</p><p><strong>Conclusions:</strong> Our results suggest that esker formation within a subglacial meltwater tunnel would be more likely on Mars than Earth, primarily because subglacial tunnels tend to be larger for equivalent water discharges, with consequent lower water flow velocities. This allows sediment deposition over longer lengths of tunnel, and to greater depths, than for terrestrial systems. Future work will use measured bed topography of a mid-latitude esker to assess the impact of topography on deposition patterns and esker morphology, and we will expand the range of discharges and sediment supply regimes investigated.</p&gt

    Eskers on Mars: Morphometric comparisons to eskers on Earth and implications for sediment-discharge dynamics of subglacial drainage

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    Mars’ present climate is extremely cold and arid. Until recently, it was widely thought that debris-covered glaciers in Mars’ mid-latitudes have been pervasively cold-based since their formation 10s–100s Myr ago. However, we recently discovered eskers associated with ~110–150 Myr old glaciers in the Phlegra Montes [1] and NW Tempe Terra [2] regions of Mars’ northern mid-latitudes. Eskers are sinuous ridges comprising sediments deposited in glacial meltwater conduits. Therefore, eskers associated with existing mid-latitude glaciers on Mars indicate that localised wet-based glaciation did occur during Mars’ most recent geological period. Eskers are important tools for reconstructing the nature, extent, and dynamics of wet-based glaciation on Earth, and have similar potential for Mars. We used 1–2 m/pixel resolution digital elevation models derived from 25–50 cm/pixel High Resolution Imaging Science Experiment stereo-pair images to measure the planform and 3D morphometries of the Phlegra Montes and NW Tempe Terra eskers, and compare them with the morphometries of Quaternary-aged eskers in Canada [3] and SW Finland [4]. We found that the Martian eskers have remarkably similar lengths, sinuosities and heights to terrestrial eskers, but that the Martian eskers are typically wider and have lower side slopes. Large width-height ratios of the Martian eskers are consistent with our previous measurements of ancient (~3.5 Ga) eskers close to Mars’ south pole [5], and may arise from differences in either: esker degradation state, or fundamental glacio-hydrological controls on esker formation between Mars and Earth. Portions of the two Martian eskers with comparable crest morphologies (e.g., sharp- or round-crested) have similar width-height relationships, suggesting that glacio-hydrological processes may exert controls upon the observed relationships between esker morphology and morphometry. Our morphometric analyses also reveal that the Martian esker in NW Tempe Terra has a ‘stacked’ morphology: the crest of a wide, round-crested underlying ridge is superposed by a narrow, sharp- to multi-crested ridge. Based on morpho-sedimentary relationships observed along terrestrial eskers [6], we interpret this transition to represent waning sediment supply and meltwater discharge towards the end of the esker-forming drainage episode(s). Direct sedimentary insights into Martian eskers are not yet possible so we emphasise that such inferences should be rigorously grounded in observations of analogous landforms on Earth. This work was funded by STFC grant ST/N50421X/1. References: [1] Gallagher, C., and Balme, M.R., (2015), Earth. Planet. Sci. Lett. 431, 96-109, [2] Butcher, F.E.G., et al. (2017), J. Geophys. Res. Planets. 122(12), 2445-2468, [3] Storrar, R.D., et al. (2014) Quat. Sci. Rev. 105, 1-25, [4] Storrar, R.D., and Jones, A., Unpublished, [5] Butcher, F.E.G., et al. (2016), Icarus 275, 65-84, [6] Burke, M.J., et al. (2010) Geol. Soc. Am. Bull. 122, 1637-1645

    Why do only some people who support parties actually join them? Evidence from Britain

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    What makes people join a political party is one of the most commonly studied questions in research on party members. Nearly all this research, however, is based on talking to people who have actually joined parties. This article simultaneously analyses surveys of members of political parties in Britain and surveys of non-member supporters of those same parties. This uniquely enables us to model the decision to join parties. The results suggest that most of the elements that constitute the influential ‘General Incentives Model’ are significant. But it also reveals that, while party supporters imagine that selective benefits, social norms and opposing rival parties’ policies are key factors in members’ decisions to join a party, those who actually do so are more likely to say they are motivated by attachments to their party’s values, policies and leaders, as well as by an altruistic desire to support democracy more generally

    A novel poly-ε-lysine based implant, Proliferate®, for promotion of CNS repair following spinal cord injury

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    The limited regenerative capacity of the CNS poses formidable challenges to the repair of spinal cord injury (SCI). Two key barriers to repair are (i) the physical gap left by the injury, and (ii) the inhibitory milieu surrounding the injury, the glial scar. Biomaterial implantation into the injury site can fill the cavity, provide a substrate for cell migration, and potentially attenuate the glial scar. We investigated the biological viability of a biocompatible and biodegradable poly-ε-lysine based biomaterial, Proliferate®, in low and high cross-linked forms and when coated with IKVAV peptide, for SCI implantation. We demonstrate altered astrocyte morphology and nestin expression on Proliferate® compared to conventional glass cell coverslips suggesting a less reactive phenotype. Moreover Proliferate® supported myelination in vitro, with myelination observed sooner on IKVAV-coated constructs compared with uncoated Proliferate®, and delayed overall compared with maintenance on glass coverslips. For in vivo implantation, parallel-aligned channels were fabricated into Proliferate® to provide cell guidance cues. Extensive vascularisation and cellular infiltration were observed in constructs implanted in vivo, along with an astrocyte border and microglial response. Axonal ingrowth was observed at the construct border and inside implants in intact channels. We conclude that Proliferate® is a promising biomaterial for implantation following SCI

    A conservation genomics workflow to guide practical management actions

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    Owing to decreasing costs and increased efficiency, it is now conceivable that conservation genomic information can be used to improve the effectiveness of recovery programs for many, if not most, threatened plants. We suggest that a simple genomic study be viewed as an initial step in conservation decision-making, as it informs long-term recovery efforts in various ways. We present biodiversity managers and conservation biologists with a simple, standardized workflow for genomic research that can guide efficient collection, analysis and application of genomic information across disparate threatened plants. Using two case studies, ‘Banksia vincentia’ and Daphnandra johnsonii, we demonstrate how a single round of genotyping by sequencing e a one-time cost e produces multiple directly applicable benefits, and how generating genomic information as early as possible can enhance conservation outcomes. We argue for a shift away from asking whether genomic information is needed or justified, and a shift towards consideration of the questions that need to be addressed. Such questions should aimed at cost-effectively guiding multiple practical aspects of a threatened plant’s management plan. The workflow presented here should help relevant stakeholders design a sampling strategy that directly suits their questions and needs

    Planning the oral health workforce: time for innovation

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    Contains fulltext : 232783.pdf (Publisher’s version ) (Open Access)The levels and types of oral health problems occurring in populations change over time, while advances in technology change the way oral health problems are addressed and the ways care is delivered. These rapid changes have major implications for the size and mix of the oral health workforce, yet the methods used to plan the oral health workforce have remained rigid and isolated from planning of oral healthcare services and healthcare expenditures. In this paper, we argue that the innovation culture that has driven major developments in content and delivery of oral health care must also be applied to planning the oral health workforce if we are to develop 'fit for purpose' healthcare systems that meet the needs of populations in the 21st century. An innovative framework for workforce planning is presented focussed on responding to changes in population needs, service developments for meeting those needs and optimal models of care delivery

    Low dietary intake of magnesium is associated with increased externalising behaviours in adolescents

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    Objective: Adequate Zn and Mg intakes may be beneficial for the prevention and treatment of mental health problems, such as depression, anxiety and attention-deficit hyperactivity disorder. We aimed to investigate the prospective association between dietary intakes of Zn and Mg and internalising and externalising behaviour problems in a population-based cohort of adolescents. Design: Prospective analysis (general linear mixed models) of dietary intakes of Zn and Mg assessed using a validated FFQ and mental health symptoms assessed using the Youth Self-Report (YSR), adjusting for sex, physical activity, family income, supplement status, dietary misreporting, BMI, family functioning and energy intake. Setting: Western Australian Pregnancy Cohort (Raine) Study. Subjects: Adolescents (n 684) at the 14- and 17-year follow-ups. Results: Higher dietary intake of Mg (per SD increase) was significantly associated with reduced externalising behaviours (β=−1·45; 95 % CI −2·40, −0·50; P=0·003). There was a trend towards reduced externalising behaviours with higher Zn intake (per SD increase; β=−0·73; 95 % CI −1·57, 0·10; P=0·085).Randomised controlled trials are necessary to determine any benefit of micronutrient supplementation in the prevention and treatment of mental health problems in adolescents.The study shows an association between higher dietary Mg intake and reduced externalising behaviour problems in adolescents. We observed a similar trend, although not statistically significant, for Zn intake. Randomised controlled trials are necessary to determine any benefit of micronutrient supplementation in the prevention and treatment of mental health problems in adolescents

    Primary care medication safety surveillance with integrated primary and secondary care electronic health records: a cross-sectional study

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    Introduction: The extent of preventable medication-related hospital admissions and medication-related issues in primary care is significant enough to justify developing decision support systems for medication safety surveillance. The prerequisite for such systems is defining a relevant set of medication safety-related indicators and understanding the influence of both patient and general practice characteristics on medication prescribing and monitoring. Objective: The aim of the study was to investigate the feasibility of linked primary and secondary care electronic health record data for surveillance of medication safety, examining not only prescribing but also monitoring, and associations with patient- and general practice-level characteristics. Methods: A cross-sectional study was conducted using linked records of patients served by one hospital and over 50 general practices in Salford, UK. Statistical analysis consisted of mixed-effects logistic models, relating prescribing safety indicators to potential determinants. Results: The overall prevalence (proportion of patients with at least one medication safety hazard) was 5.45 % for prescribing indicators and 7.65 % for monitoring indicators. Older patients and those on multiple medications were at higher risk of prescribing hazards, but at lower risk of missed monitoring. The odds of missed monitoring among all patients were 25 % less for males, 50 % less for patients in practices that provide general practitioner training, and threefold higher in practices serving the most deprived compared with the least deprived areas. Practices with more prescribing hazards did not tend to show more monitoring issues. Conclusions:Systematic collection, collation, and analysis of linked primary and secondary care records produce plausible and useful information about medication safety for a health system. Medication safety surveillance systems should pay close attention to patient age and polypharmacy with respect to both prescribing and monitoring failures; treat prescribing and monitoring as different statistical processes, rather than a combined measure of prescribing safety; and audit the socio-economic equity of missed monitoring
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