10 research outputs found
The role of dendritic cells in the immunopathogenesis of psoriasis
Psoriasis vulgaris is a chronic inflammatory skin disease that is marked by a complex interplay of dendritic cells (DCs), T-cells, cytokines, and downstream transcription factors as part of a self-sustaining type 1 cytokine network. As integral players of the immune system, DCs represent antigen-presenting cells that are crucial for efficient activation of T-cells and B-cells. DCs have also been linked to distinct chronic inflammatory conditions, including psoriasis. In the setting of psoriasis therapy, DC/T cell interactions serve as a potential target for biologic response modifiers. Here we describe the major DC subsets as well as the immunologic involvement of DCs within the context of psoriatic lesions
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Urban trees and asthma: a call for epidemiological research
The Lancet Respiratory Medicine is the top-ranked Respiratory System medical journal (1/96) by Journal Citation Reports
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Urban trees, air quality, and asthma: an interdisciplinary review
Landscape and Urban Planning is the 2019 top-ranked Urban Studies journal (1/42) by Journal Citation Reports
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Reliever-Triggered Inhaled Glucocorticoid in Black and Latinx Adults with Asthma
Although reliever-triggered inhaled glucocorticoid therapy can reduce asthma exacerbations, this approach has not been well studied in Black and Latinx populations, who bear disproportionate asthma morbidity and mortality. In a pragmatic trial involving Black and Latinx patients, the asthma exacerbation rate was lower with reliever-triggered inhaled glucocorticoid use than with usual care