A Model for Investigating Developmental Eye Repair in Xenopus Laevis

Vertebrate eye development is complex and requires early interactions between neuroectoderm and surface ectoderm during embryogenesis. In the African clawed frog, Xenopus laevis, individual eye tissues such as the retina and lens can undergo regeneration. However, it has been reported that removal of either the specified eye field at the neurula stage or the eye during tadpole stage does not induce replacement. Here we describe a model for investigating Xenopus developmental eye repair. We found that tailbud embryos can readily regrow eyes after surgical removal of over 83% of the specified eye and lens tissues. The regrown eye reached a comparable size to the contralateral control by 5 days and overall animal development was normal. It contained the expected complement of eye cell types (including the pigmented epithelium, retina and lens), and is connected to the brain. Our data also demonstrate that apoptosis, an early mechanism that regulates appendage regeneration, is also required for eye regrowth. Treatment with apoptosis inhibitors (M50054 or NS3694) blocked eye regrowth by inhibiting caspase activation. Together, our findings indicate that frog embryos can undergo successful eye repair after considerable tissue loss and reveals a required role for apoptosis in this process. Furthermore, this Xenopus model allows for rapid comparisons of productive eye repair and developmental pathways. It can also facilitate the molecular dissection of signaling mechanisms necessary for initiating repair

Extended X-ray Emission From a Quasar-Driven Superbubble

We present observations of extended, 20-kpc scale soft X-ray gas around a luminous obscured quasar hosted by an ultra-luminous infrared galaxy caught in the midst of a major merger. The extended X-ray emission is well fit as a thermal gas with a temperature of kT ~ 280 eV and a luminosity of L_X ~ 10^42 erg/s and is spatially coincident with a known ionized gas outflow. Based on the X-ray luminosity, a factor of ~10 fainter than the [OIII] emission, we conclude that the X-ray emission is either dominated by photoionization, or by shocked emission from cloud surfaces in a hot quasar-driven wind.Comment: Accepted for publication in ApJ, 6 pages, 2 figure

Oscillatory pairing of fermions in spin-split traps

As a means of realizing oscillatory pairing between fermions, we study superfluid pairing between two fermion "spin" species that are confined to adjustable spin-dependent trapping potentials. Focusing on the one-dimensional limit, we find that with increasing separation between the spin-dependent traps the fermions exhibit distinct phases, including a fully paired phase, a spin-imbalanced phase with oscillatory pairing, and an unpaired fully spin-polarized phase. We obtain the phase diagram of fermions in such a spin-split trap and discuss signatures of these phases in cold-atom experiments.Comment: 5 pages, 5 figures, RevTe

Managing Forests and Water for People under a Changing Environment

The Earth has entered the Anthropocene epoch and forest managers are facing unprecedented challenges to meet multiple ecosystem service demands from forests. Understanding the complex forest-water relations under a changing environment must add a human dimension, and this is essential in the move towards sustainable forest management in the 21st century. This Special Issue contains 10 papers presented at a joint international forest and water conference in Chile in 2018. These studies provide global examples on new advancements in sciences in forest ecohydrology, watershed management, and ecosystem service assessment under various geographical and socioeconomic settings

Oxytocin increases emotional theory of mind, but only for low socioeconomic status individuals.

Studies have linked oxytocin to emotional theory of mind (eToM) - the ability to recognise and understand others' emotions. However, multiple replications have so far failed to reach a consistent result. Growing evidence suggests that oxytocin's positive effects on social-emotional tasks such as eToM are highly dependent on trait-level individual differences. In the present study, we theorised that socioeconomic status (SES) could influence oxytocin's impact on emotional mentalising processes. We tested our hypothesis in a double-blind between-subjects oxytocin nasal spray study on 147 Caucasian white male participants in the United Kingdom. In accordance with our hypothesis, we found that oxytocin (as compared to placebo) did boost emotional theory of mind, but only in people from low subjective SES backgrounds. Our results expand existing theory on how individual differences moderate oxytocin's role on social behaviours

Organic Matter in the Surface Microlayer: Insights From a Wind Wave Channel Experiment

The surface microlayer (SML) is the uppermost thin layer of the ocean and influencing interactions between the air and sea, such as gas exchange, atmospheric deposition and aerosol emission. Organic matter (OM) plays a key role in air-sea exchange processes, but studying how the accumulation of organic compounds in the SML relates to biological processes is impeded in the field by a changing physical environment, in particular wind speed and wave breaking. Here, we studied OM dynamics in the SML under controlled physical conditions in a large annular wind wave channel, filled with natural seawater, over a period of 26 days. Biology in both SML and bulk water was dominated by bacterioneuston and -plankton, respectively, while autotrophic biomass in the two compartments was very low. In general, SML thickness was related to the concentration of dissolved organic carbon (DOC) but not to enrichment of DOC or of specific OM components in the SML. Pronounced changes in OM enrichment and molecular composition were observed in the course of the study and correlated significantly to bacterial abundance. Thereby, hydrolysable amino acids, in particular arginine, were more enriched in the SML than combined carbohydrates. Amino acid composition indicated that less degraded OM accumulated preferentially in the SML. A strong correlation was established between the amount of surfactants coverage and γ-aminobutric acid, suggesting that microbial cycling of amino acids can control physiochemical traits of the SML. Our study shows that accumulation and cycling of OM in the SML can occur independently of recent autotrophic production, indicating a widespread biogenic control of process across the air-sea exchange