23 research outputs found
Investigating the nutritional potential and vegetation blueprint mapping of Acacia tortilis and Acacia ehrenbergiana from the origin of Fujairah, UAE, for Arabian Tahr as native fodder plants
Background: Acacia ehrenbergiana and Acacia tortilis are the native plant of the Emirates of Fujairah, UAE. The qualities of these plants of bearing harsh environmental conditions makes it prime focus for native fodder plants for Arabian tahr and the priority plants for the Higher authorities in Fujairah.Methods: The following study has assessed the comparative nutritional values of Acacia tortilis and Acacia ehrenbergiana. The analyses have been determined by international standard procedures using Gravimetry, Soxhlet extraction, HPLC, and ICP-OES(AOAC 962.09, AOAC 941.12). The vegetation mapping for the blooming period has been done by NVDI using data from Sentinel-2 satellite. The statistics of agricultural and non-agriculture areas in kilometer square (km2) have been found to confirm the findings of the NDVI using the satellite images.Results: The study has highlighted the importance of these native plants as a fodder plant for Arabian tahr as potential source of potassium, calcium, and magnesium and phosphorus. Furthermore, the native plant's mapping showed Emirates of Fujairah's vegetation during March to May 2022.Conclusion: Results shows that the A. ehrenbergiana is comparatively healthier diet for Arabian Tahr than Acacia tortilis. Tahr can get on average 400 mg/100g of four important minerals including K, Ca, P and Mg while Acacia tortilis could provide 174 mg/100g. Moreover, the native plant’s vegetation mapping can work as blueprint and will help identify plant dispersion and expansion planning.Keywords: Acacia ehrenbergiana; Acacia tortilis; priority plant; Fujairah; Arabian Tahr; Extinction, Gravimetry, Soxhlet extraction; HPLC; ICP-OES; blueprint mapping; NVDI; Sentinel-2 Â
Clinical Management in Diagnosis and Treatment of the Iron Deficiency Anemia in Adults: Systemic Review
This study aimed at exploring with a systematic review the clinical management in diagnosis and treatment of the iron deficiency anemia in adults, as the iron deficiency is the most frequent cause of anemia worldwide. And it impairs quality of life, increases asthenia and can lead to clinical worsening of patients. In addition, iron deficiency has a complex mechanism whose pathologic pathway is recently becoming better understood. This review summarizes the current knowledge regarding diagnostic algorithms for iron deficiency anemia. The majority of aetiologies occur in the digestive tract, and justify morphological examination of the gut. First line investigations are upper gastrointestinal endoscopy and colonoscopy, and when negative, the small bowel should be explored; newer tools such as video capsule endoscopy have also been developed. The treatment of iron deficiency is aetiological if possible and iron supplementation whether in oral or in parenteral form.
Effect of General Anesthesia on Postoperative Cognitive Function in Elderly Patients
The prevalence of postoperative cognitive dysfunction continues to be significant following surgical procedures. It has been posited that external factors, among which the type of anesthesia plays a vital role, are significant contributors to POCD. In older adults, cognitive decline post-surgery can lead to devastating physical, psychological, and societal impacts. Advancing our comprehension of cognitive deterioration postoperatively is critical for eradicating this potentially avoidable contributor to cognitive decline. Therefore, a thorough grasp of the cognitive repercussions of various anesthetic agents used intraoperatively has become crucial. This surge of interest has propelled research focusing on the repercussions of general anesthesia on post-surgical cognitive abilities. The objective of this literature review is to enrich readers\u27 insights into POCD among the geriatric demographic and to scrutinize the evidence of how various anesthetic components—mainstay anesthetics, supplemental agents, and sedatives—influence postoperative cognition. Prior to the 1950s assumptions, it was surmised that anesthesia merely rendered cerebral functions dormant during surgery, with normalcy resuming upon awakening. Contemporary understanding now acknowledges the nuanced impact of anesthetics, which instigate distinctive alterations in specific cerebral activities and memory capacities. Concerns about post-surgical cognitive deficit burgeoned with the advent of inhalational anesthetic pharmacology, paralleled by heightened life expectancy and health service utilization in the aging population. While minor surgical interventions like dental extractions, often under local anesthesia, were thought to yield better cognitive outcomes, this notion was upended by Bedford\u27s revelation in 1960 that major surgical procedures such as coronary bypass, involving cardiopulmonary bypass and extended hypothermia, markedly disrupted cognitive faculties. This link between significant surgical interventions and cognitive impairment fueled further inquiry into the influence of surgery and anesthetic agents on postoperative brain function. The late 1970s witnessed heightened awareness of postoperative "forgetfulness" in the aged, evolving into substantial focus in the late 1990s. At that point, profound documentation surfaced indicating cognitive decline post-surgery was pervasive across all ages but was especially pronounced in elderly individuals—representing a critical public health concern. The era following this revelation has witnessed an avalanche of studies probing into POCD
Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
Background Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide.Methods A multimethods analysis was performed as part of the GlobalSurg 3 study-a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital.Findings Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3.85 [95% CI 2.58-5.75]; p<0.0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63.0% vs 82.7%; OR 0.35 [0.23-0.53]; p<0.0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer.Interpretation Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised
Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study
Summary
Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally.
Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies
have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of
the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income
countries globally, and identified factors associated with mortality.
Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to
hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis,
exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a
minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical
status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary
intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause,
in-hospital mortality for all conditions combined and each condition individually, stratified by country income status.
We did a complete case analysis.
Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital
diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal
malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome
countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male.
Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3).
Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income
countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups).
Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome
countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries;
p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients
combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11],
p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20
[1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention
(ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety
checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed
(ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of
parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65
[0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality.
Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome,
middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will
be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger
than 5 years by 2030
Uncovering the impact of AM fungi on wheat nutrient uptake, ion homeostasis, oxidative stress, and antioxidant defense under salinity stress
Abstract The growth of wheat (Triticum aestivum) is constrained by soil salinity, although some fungal species have been shown to enhance production in saline environments. The yield of grain crops is affected by salt stress, and this study aimed to investigate how arbuscular mycorrhizal fungus (AMF) mitigates salt stress. An experiment was conducted to assess the impact of AMF on wheat growth and yield in conditions of 200Â mM salt stress. Wheat seeds were coated with AMF at a rate of 0.1Â g (108 spores) during sowing. The results of the experiment demonstrated that AMF inoculation led to a significant improvement in the growth attributes of wheat, including root and shoot length, fresh and dry weight of root and shoot. Furthermore, a significant increase in chlorophyll a, b, total, and carotenoids was observed in the S2 AMF treatment, validating the effectiveness of AMF in enhancing wheat growth under salt stress conditions. Additionally, AMF application reduced the negative effects of salinity stress by increasing the uptake of micronutrients such as Zn, Fe, Cu, and Mn while regulating the uptake of Na (decrease) and K (increase) under salinity stress. In conclusion, this study confirms that AMF is a successful strategy for reducing the negative effects of salt stress on wheat growth and yield. However, further investigations are recommended at the field level under different cereal crops to establish AMF as a more effective amendment for the alleviation of salinity stress in wheat
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Patient satisfaction and quality of life in Mohs micrographic surgery: A randomized controlled clinical trial
Prediction of the fuel spray characteristics in the combustion chamber with methane and TiO2 nanoparticles via numerical modelling
In this study the methane combustion was analysed with the TiO2 nanoparticles. A series of the simulation runs were performed by varying the fuel inlet velocity. However, the oxidizer and the nanoparticles spray were maintained constant for the entire run. The spray velocity varied from 100 m/s to 200 m/s with titanium dioxide (TiO2) nanoparticles. Using the series of the governing equation and modified Navier Stokes equation the model has been developed with the aid of numerical workbench. Three different domains are generated for fuel, oxidizer and nanoparticles. The velocity of the air and nanoparticles were maintained at constant levels and varying only the spray velocity of the fuel. Based on the findings, the mass fraction of both fuel and formation of the CO2 were dependent on the spray velocity. As the spray velocity increases the turbulence in the combustion chamber increases which ensures the higher mixing of both air-fuel and nanoparticles. From the procured findings 175 m/s and 200 m/s were the ideal range for better combustion efficiency compared to 100 m/s and 150 m/s. The simulation results have ascertained the role of the spray velocity on the emissions and the combustion efficiency of the engine. It is hoped that obtained results can provide directions to work on the combustion of the methane with the nanoparticles at the optimized spray velocity.2021-KYYWF-0563, RSP-2021/315; King Saud University, KSUHeilongjiang Universities [2021-KYYWF-0563]; Researchers Supporting Project, King Saud University, Riyadh, Saudi Arabia [RSP-2021/315]; Van Lang University, Vietna