Nonlinear Analysis of the Eckhaus Instability: Modulated Amplitude Waves and Phase Chaos with Non-zero Average Phase Gradient

We analyze the Eckhaus instability of plane waves in the one-dimensional complex Ginzburg-Landau equation (CGLE) and describe the nonlinear effects arising in the Eckhaus unstable regime. Modulated amplitude waves (MAWs) are quasi-periodic solutions of the CGLE that emerge near the Eckhaus instability of plane waves and cease to exist due to saddle-node bifurcations (SN). These MAWs can be characterized by their average phase gradient $\nu$ and by the spatial period P of the periodic amplitude modulation. A numerical bifurcation analysis reveals the existence and stability properties of MAWs with arbitrary $\nu$ and P. MAWs are found to be stable for large enough $\nu$ and intermediate values of P. For different parameter values they are unstable to splitting and attractive interaction between subsequent extrema of the amplitude. Defects form from perturbed plane waves for parameter values above the SN of the corresponding MAWs. The break-down of phase chaos with average phase gradient $\nu$ > 0 (``wound-up phase chaos'') is thus related to these SNs. A lower bound for the break-down of wound-up phase chaos is given by the necessary presence of SNs and an upper bound by the absence of the splitting instability of MAWs.Comment: 24 pages, 14 figure

Constructing a bivariate distribution function with given marginals and correlation: application to the galaxy luminosity function

We show an analytic method to construct a bivariate distribution function (DF) with given marginal distributions and correlation coefficient. We introduce a convenient mathematical tool, called a copula, to connect two DFs with any prescribed dependence structure. If the correlation of two variables is weak (Pearson's correlation coefficient $|\rho| <1/3$), the Farlie-Gumbel-Morgenstern (FGM) copula provides an intuitive and natural way for constructing such a bivariate DF. When the linear correlation is stronger, the FGM copula cannot work anymore. In this case, we propose to use a Gaussian copula, which connects two given marginals and directly related to the linear correlation coefficient between two variables. Using the copulas, we constructed the BLFs and discuss its statistical properties. Especially, we focused on the FUV--FIR BLF, since these two luminosities are related to the star formation (SF) activity. Though both the FUV and FIR are related to the SF activity, the univariate LFs have a very different functional form: former is well described by the Schechter function whilst the latter has a much more extended power-law like luminous end. We constructed the FUV-FIR BLFs by the FGM and Gaussian copulas with different strength of correlation, and examined their statistical properties. Then, we discuss some further possible applications of the BLF: the problem of a multiband flux-limited sample selection, the construction of the SF rate (SFR) function, and the construction of the stellar mass of galaxies ($M_*$)--specific SFR ($SFR/M_*$) relation. The copulas turned out to be a very useful tool to investigate all these issues, especially for including the complicated selection effects.Comment: 14 pages, 5 figures, accepted for publication in MNRAS

Keratinocyte growth factor for the treatment of the acute respiratory distress syndrome (KARE): a randomised, double-blind, placebo-controlled phase 2 trial

<p>(<b>A</b>) Immunofluorescence signal for dystrophin is significantly reduced in the SSI heart (bottom left panel) compared with the immunofluorescent signal in the SHAM heart (upper left panel), and the SHAM+ALLN (upper right panel) and SSI+ALLN (bottom right panel) myocardium. (<b>B</b>) Protein levels of dystrophin in the SHAM, SSI, SHAM+ALLN and SSI+ALLN hearts were measured 24 h after the CLP procedure and were expressed in arbitrary units (AUs). α-Tubulin was used to determine equivalent loading conditions. The results (n = 6 per group) are representative of three different experiments. Scale bars indicate 50 μm.</p

Parametric Forcing of Waves with Non-Monotonic Dispersion Relation: Domain Structures in Ferrofluids?

Surface waves on ferrofluids exposed to a dc-magnetic field exhibit a non-monotonic dispersion relation. The effect of a parametric driving on such waves is studied within suitable coupled Ginzburg-Landau equations. Due to the non-monotonicity the neutral curve for the excitation of standing waves can have up to three minima. The stability of the waves with respect to long-wave perturbations is determined $via$ a phase-diffusion equation. It shows that the band of stable wave numbers can split up into two or three sub-bands. The resulting competition between the wave numbers corresponding to the respective sub-bands leads quite naturally to patterns consisting of multiple domains of standing waves which differ in their wave number. The coarsening dynamics of such domain structures is addressed.Comment: 23 pages, 6 postscript figures, composed using RevTeX. Submitted to PR

Nonlinear Modulation of Multi-Dimensional Lattice Waves

The equations governing weakly nonlinear modulations of $N$-dimensional lattices are considered using a quasi-discrete multiple-scale approach. It is found that the evolution of a short wave packet for a lattice system with cubic and quartic interatomic potentials is governed by generalized Davey-Stewartson (GDS) equations, which include mean motion induced by the oscillatory wave packet through cubic interatomic interaction. The GDS equations derived here are more general than those known in the theory of water waves because of the anisotropy inherent in lattices. Generalized Kadomtsev-Petviashvili equations describing the evolution of long wavelength acoustic modes in two and three dimensional lattices are also presented. Then the modulational instability of a $N$-dimensional Stokes lattice wave is discussed based on the $N$-dimensional GDS equations obtained. Finally, the one- and two-soliton solutions of two-dimensional GDS equations are provided by means of Hirota's bilinear transformation method.Comment: Submitted to PR

Legal determinants of external finance revisited : the inverse relationship between investor protection and societal well-being

This paper investigates relationships between corporate governance traditions and quality of life as measured by a number of widely reported indicators. It provides an empirical analysis of indicators of societal health in developed economies using a classification based on legal traditions. Arguably the most widely cited work in the corporate governance literature has been the collection of papers by La Porta et al. which has shown, inter alia, statistically significant relationships between legal traditions and various proxies for investor protection. We show statistically significant relationships between legal traditions and various proxies for societal health. Our comparative evidence suggests that the interests of investors may not be congruent with the interests of wider society, and that the criteria for judging the effectiveness of approaches to corporate governance should not be restricted to financial metrics

Asymmetric gap soliton modes in diatomic lattices with cubic and quartic nonlinearity

Nonlinear localized excitations in one-dimensional diatomic lattices with cubic and quartic nonlinearity are considered analytically by a quasi-discreteness approach. The criteria for the occurence of asymmetric gap solitons (with vibrating frequency lying in the gap of phonon bands) and small-amplitude, asymmetric intrinsic localized modes (with the vibrating frequency being above all the phonon bands) are obtained explicitly based on the modulational instabilities of corresponding linear lattice plane waves. The expressions of particle displacement for all these nonlinear localized excitations are also given. The result is applied to standard two-body potentials of the Toda, Born-Mayer-Coulomb, Lennard-Jones, and Morse type. The comparison with previous numerical study of the anharmonic gap modes in diatomic lattices for the standard two-body potentials is made and good agreement is found.Comment: 24 pages in Revtex, 2 PS figure

Dynamical Reduction of Discrete Systems Based on the Renormalization Group Method

The renormalization group (RG) method is extended for global asymptotic analysis of discrete systems. We show that the RG equation in the discretized form leads to difference equations corresponding to the Stuart-Landau or Ginzburg-Landau equations. We propose a discretization scheme which leads to a faithful discretization of the reduced dynamics of the original differential equations.Comment: LaTEX. 12pages. 1 figure include

Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5

The 5'-cap-structures of higher eukaryote mRNAs are ribose 2'-O-methylated. Likewise, a number of viruses replicating in the cytoplasm of eukayotes have evolved 2'-O-methyltransferases to modify autonomously their mRNAs. However, a defined biological role of mRNA 2'-O-methylation remains elusive. Here we show that viral mRNA 2'-O-methylation is critically involved in subversion of type-I-interferon (IFN-I) induction. We demonstrate that human and murine coronavirus 2'-O-methyltransferase mutants induce increased IFN-I expression, and are highly IFN-I sensitive. Importantly, IFN-I induction by 2'-O-methyltransferase-deficient viruses is dependent on the cytoplasmic RNA sensor melanoma differentiation-associated gene 5 (MDA5). This link between MDA5-mediated sensing of viral RNA and mRNA 2'-O-methylation suggests that RNA modifications, such as 2'-O-methylation, provide a molecular signature for the discrimination of self and non-self mRNA