S-LDM: Server Local Dynamic Map for 5G-based Centralized Enhanced Collective Perception

The automotive field is undergoing significant technological advances, which includes making the next generation of autonomous vehicles smarter, greener and safer through vehicular networks, which are often referred to as Vehicle-to-Everything (V2X) communications. Together with V2X, centralized maneuver management services for autonomous vehicles are increasingly gaining importance, as, thanks to their complete view over the road, they can optimally manage even the most complex maneuvers targeting L4 driving and beyond. These services face the challenge of strictly requiring a high reliability and low latency, which are tackled with the deployment at orchestrated Multi-Access Edge Computing (MEC) platforms. In order to properly manage safety-critical maneuvers, these services need to receive a large amount of data from vehicles, even though the useful subset of data is often related to a specific context on the road (e.g., to specific road users or geographical areas). Decoding and post-processing a large amount of raw messages, which are then for the most part filtered, increases the load on safety-critical services, which should instead focus on meeting the deadlines for the actual control and management operations. On this basis, we present an innovative open-source, 5G & MEC enabled service, called Server Local Dynamic Map (S-LDM). The S-LDM is a service that collects information about vehicles and other non-connected road objects using standard-compliant messages. Its primary purpose is to create a centralized dynamic map of the road that can be shared efficiently with other services managing L4 automation, when needed. By doing so, the S-LDM enables these services to widely and precisely understand the current situation of sections of the road, offloading them from the need of quickly processing a large number of messages. After a detailed description of the service architecture, we validate it through extensive laboratory and pilot trials, involving the MEC platforms and production 5G networks of three major European network operations and two Stellantis vehicles equipped with V2X On-Board Units (OBUs). We show how it can efficiently handle high update rates and process each messages in less than few tenths of microseconds. We also provide a complete scalability analysis with details on deployment options, providing insights on where new instances should be created in practical 5G-based V2X scenarios

A global point prevalence survey of antimicrobial use in neonatal intensive care units: The no-more-antibiotics and resistance (NO-MAS-R) study

Background: Global assessment of antimicrobial agents prescribed to infants in the neonatal intensive care unit (NICU) may inform antimicrobial stewardship efforts. Methods: We conducted a one-day global point prevalence study of all antimicrobials provided to NICU infants. Demographic, clinical, and microbiologic data were obtained including NICU level, census, birth weight, gestational/chronologic age, diagnoses, antimicrobial therapy (reason for use; length of therapy), antimicrobial stewardship program (ASP), and 30-day in-hospital mortality. Findings: On July 1, 2019, 26 of infants (580/2,265; range, 0�100; median gestational age, 33 weeks; median birth weight, 1800 g) in 84 NICUs (51, high-income; 33, low-to-middle income) from 29 countries (14, high-income; 15, low-to-middle income) in five continents received �1 antimicrobial agent (92, antibacterial; 19, antifungal; 4, antiviral). The most common reasons for antibiotic therapy were �rule-out� sepsis (32) and �culture-negative� sepsis (16) with ampicillin (40), gentamicin (35), amikacin (19), vancomycin (15), and meropenem (9) used most frequently. For definitive treatment of presumed/confirmed infection, vancomycin (26), amikacin (20), and meropenem (16) were the most prescribed agents. Length of therapy for culture-positive and �culture-negative� infections was 12 days (median; IQR, 8�14) and 7 days (median; IQR, 5�10), respectively. Mortality was 6 (42, infection-related). An NICU ASP was associated with lower rate of antibiotic utilization (p = 0·02). Interpretation: Global NICU antibiotic use was frequent and prolonged regardless of culture results. NICU-specific ASPs were associated with lower antibiotic utilization rates, suggesting the need for their implementation worldwide. Funding: Merck & Co.; The Ohio State University College of Medicine Barnes Medical Student Research Scholarship © 2021 The Author

Reclaimed wastewater: Effects on citrus nutrition

The effects of irrigation with reclaimed wastewater (RWW) were compared with well water (WW) on citrus (Citrus paradisi Macfad. X Citrus aurantium L) nutrition. The deviation from the optimum percentage (DOP) index of macro- and micro-nutrients were used to evaluate the nutritional status: optimal (DOP = 0), deficiency (DOP < 0) or excess (DOP > 0). After 11 years of RWW irrigation the influence on nutrient concentration in plants decreased in the order: B > Zn > Mn = Ca > Cu > Mg > P > K. Reclaimed wastewater irritation positively affected citrus nutrition as it rendered the concentration of macronutrients, i.e. P, Ca, and K. closer to their optimum levels (Sigma DOP(macro) = 7). However micro-nutrients tended to be excessive in plants (EDOP(micro) = 753) due to imbalanced supply of these elements in the RWW, particularly, for B and Cu. Citrus groves with long-term RWW irrigation may exercised caution in monitoring concentrations of B and Cu to avoid plant toxicity and soil quality degradation. (C) 2011 Elsevier B.V. All rights reserved.FAPESP (Sao Paulo Research Foundation)[06/56419-6]University of Florid

Table_2_The paleo-ecological application of mollusks in the calculation of saltwater encroachment and resultant changes in depositional patterns driven by the Anthropocene Marine Transgression.docx

Numerous studies address changes in wetland deposition in response to saltwater encroachment driven by the accelerating rate of sea-level rise, by quantifying temporal changes recovered from a vertical sediment sequence. This is the first landscape scale study, based upon 10 core transects representing the heterogeneity of the Southeast Saline Everglades, Florida. By utilizing the known salinity preferences of molluscan assemblages, a Salinity Index was calculated for each core sequence and the recorded salinity changes identified and dated. Radiometric dating utilizing the 210Pb method provides the rate of sediment accumulation and the date of changes identified in the core. The core transects provide the basis for calculation of the rate of saltwater encroachment by comparing the date of saltwater encroachment and the distance between two cores. Thereby, temporal and spatial changes in other sediment parameters in a landscape can also be quantified, such as organic carbon. This paleo-ecological approach to rapidly changing coastal conditions can be utilized to provide scientists and land managers with a record of the past, rate of changing conditions and provide the basis for predicting the future trajectory of their site. Application of this paleo-ecological approach documented increasing rates of saltwater encroachment associated with accelerating rate of sea-level rise: an average rate of 49.1 between 1895 and 1940, 69.2 between 1940 and 1968, 73 between 1968 and 1995 and 131.1 m/yr between 1995 and 2015. Approximately 1.79 km of saltwater encroachment has occurred since 1995, with three partial reversals because of increased freshwater delivery. Associated with saltwater encroachment are changes in sediment organic carbon, decreasing area of marl production and increasing distribution of mangrove. Although the distance of saltwater encroachment is greater in Florida Bay, both changes in sediment organic carbon and mangrove distribution are much less than in Biscayne Bay coastal basins. This heterogeneity is likely the result of differences in tidal ingress efficiency. At the present rate of saltwater encroachment, the freshwater wetlands are predictably lost within a century.</p