Alien Registration- Morgan, Stephen L. (Baldwin, Cumberland County)

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The Florida Governor\u27s Commission on Space: Its Impact on Space Enterprise

At the Kennedy Space Center, on 28 Her/ 1987, at the Second Briefing Meeting of the East Central Florida Space Business Roundtable, Florida Governor Bob Martlnez signed an Executive Order creating the Governor\u27s Commission on Space. This action followed the Roundtable\u27s initiative to the state dating from September, 1986, suggesting the formation of the Commission. On hand to deliver the keynote address was Dr. Gerard K. O\u27Nelll, a former member of the National Commission on Space. Dr. O\u27Neill\u27s presence was no accident, since the purpose of the Florida Commission is to define Florida\u27s role in the continued development of many of the concepts outlined In the National Commission\u27s watershed report, Pioneering the Space Frontier. The Florida Commission identified nine topical areas for further research, and its work is still in progress. A number of legislative recommendations have already been presented to the Governor, while the final report is not due until June, 1988. This Commission, and several similar efforts in other states, is indicative of the strong interest nationally in the development of space enterprise

The Estimation of Causal Effects from Observational Data

When experimental designs are infeasible, researchers must resort to the use of observational data from surveys, censuses, and administrative records. Because assignment to the independent variables of observational data is usually nonrandom, the challenge of estimating causal effects with observational data can be formidable. In this chapter, we review the large literature produced primarily by statisticians and econometricians in the past two decades on the estimation of causal effects from observational data. We first review the now widely accepted counterfactual framework for the modeling of causal effects. After examining estimators, both old and new, that can be used to estimate causal effects from cross-sectional data, we present estimators that exploit the additional information furnished by longitudinal data. Because of the size and technical nature of the literature, we cannot offer a fully detailed and comprehensive presentation. Instead, we present only the main features of methods that are accessible and potentially of use to quantitatively oriented sociologists.Sociolog

Advocating the Development of Space Enterprise: The Space Business Roundtable Movement Nationwide

Space Business Roundtables nationwide are building an important constituency for the future of space enterprise development. The Roundtables serve as space chambers of commerce In their local areas, bringing together Individuals and organizations from diverse areas in general and technical business, local, state, and federal government, the military, and the academic community. General direction Is provided through a national affiliation with the Space Foundation , Inc., of Houston, Texas, while each Individual Roundtable is organized and managed in a manner to best serve Its local community. Currently, there are seven Roundtables chartered by the Space Foundation. Roundtable members, and Roundtables as organizations, are beginning to have an impact on the development of space policy, and on the attitude of the business community toward space enterprise. The Florida Roundtable, founded in 1 986, is one of the most active Roundtables in the country, conducting a full agenda of Briefing Meetings, Roundtable Workshops and Seminars, and publishing Roundtable Script and Space Business Briefing. INTRODUCTIO

The Natural History of Hepatitis C Virus (HCV) Infection

Hepatitis C virus (HCV) is a leading cause of chronic liver disease, cirrhosis, and hepatocellular carcinoma, as well as the most common indication for liver transplantation in many countries. Although the incidence of hepatitis C infection has dramatically decreased during the past decade, the worldwide reservoir of chronically infected persons is estimated at 170 million, or 3% of the global population. There is much controversy surrounding the natural history of hepatitis C infection. The rate of chronic HCV infection is affected by a person's age, gender, race, and viral immune response. Approximately 75%-85% of HCV-infected persons will progress to chronic HCV infection, and are at risk for the development of extrahepatic manifestations, compensated and decompensated cirrhosis, and hepatocellular carcinoma (HCC). The rate of progression to cirrhosis is highly variable, and is influenced by several factors, including the amount of alcohol consumption, age of initial HCV infection, degree of inflammation and fibrosis on liver biopsy, HIV and HBV coinfection, and comordid conditions. An estimated 10%-15% of HCV-infected persons will advance to cirrhosis within the first 20 years. Persons with cirrhosis are at increased risk of developing HCC. An understanding of the natural history of hepatitis C is essential to effectively manage, treat, and counsel individuals with HCV infection

Can health economics aid decision making in healthcare innovation in academia?

Health economics is extensively used by reimbursement agencies to make decisions on whether to adopt new medical technologies. It is also used by the healthcare industry as an aid to decision making during product development. This paper proposes that academic healthcare technology transfer could also benefit from adopting health economics. The study investigated the knowledge and attitudes of academic staff involved in developing and transferring healthcare technologies. The participants had little or no prior knowledge of health economics; however, the majority reported that this method had the potential to aid development and commercialisation. The innovations developed by the workshop attendees and their commercialisation plans were of a type that could potentially benefit from cost-effectiveness calculations. Health economics has the potential to make valuable contribution to academic healthcare innovation. Research is required to develop this method further and ensure that it can be successfully applied in academia

Ultrasound-mediation of self-illuminating reporters improves imaging resolution in optically scattering media

In vivo imaging of self-illuminating bio-and chemiluminescent reporters is used to observe the physiology of small animals. However, strong light scattering by biological tissues results in poor spatial resolution of the optical imaging, which also degrades the quantitative accuracy. To overcome this challenging problem, focused ultrasound is used to modulate the light from the reporter at the ultrasound frequency. This produces an ultrasound switchable light ‘beacon’ that reduces the influence of light scattering in order to improve spatial resolution. The experimental results demonstrate that apart from light modulation at the ultrasound frequency (AC signal at 3.5 MHz), ultrasound also increases the DC intensity of the reporters. This is shown to be due to a temperature rise caused by insonification that was minimized to be within acceptable mammalian tissue safety thresholds by adjusting the duty cycle of the ultrasound. Line scans of bio-and chemiluminescent objects embedded within a scattering medium were obtained using ultrasound modulated (AC) and ultrasound enhanced (DC) signals. Lateral resolution is improved by a factor of 12 and 7 respectively, as compared to conventional CCD imaging. Two chemiluminescent sources separated by ~10mm at ~20 mm deep inside a 50 mm thick chicken breast have been successfully resolved with an average signal-to-noise ratio of approximately 8-10 dB