110 research outputs found

    Paleo-Balkan and Slavic Contributions to the Genetic Pool of Moldavians

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    Moldova has a rich historical and cultural heritage, which may be reflected in the current genetic makeup of its population. To date, no comprehensive studies exist about the population genetic structure of modern Moldavians. To bridge this gap with respect to paternal lineages, we analyzed 37 binary and 17 multiallelic (STRs) polymorphisms on the non-recombining portion of the Y chromosome in 125 Moldavian males. In addition, 53 Ukrainians from eastern Moldova and 54 Romanians from the neighboring eastern Romania were typed using the same set of markers. In Moldavians, 19 Y chromosome haplogroups were identified, the most common being I-M423 (20.8%), R-M17* (17.6%), R-M458 (12.8%), E-v13 (8.8%), RM269* and R-M412* (both 7.2%). In Romanians, 14 haplogroups were found including I-M423 (40.7%), R-M17* (16.7%), RM405 (7.4%), E-v13 and R-M412* (both 5.6%). In Ukrainians, 13 haplogroups were identified including R-M17 (34.0%), I-M423 (20.8%), R-M269* (9.4%), N-M178, R-M458 and R-M73 (each 5.7%). Our results show that a significant majority of the Moldavian paternal gene pool belongs to eastern/central European and Balkan/eastern Mediterranean Y lineages. Phylogenetic and AMOVA analyses based on Y-STR loci also revealed that Moldavians are close to both eastern/central European and Balkan-Carpathian populations. The data correlate well with historical accounts and geographical location of the region and thus allow to hypothesize that extant Moldavian paternal genetic lineages arose from extensive recent admixture between genetically autochthonous populations of the Balkan-Carpathian zone and neighboring Slavic group

    Π‘ΠΎΠ»ΡŒΡˆΠ΅, Ρ‡Π΅ΠΌ ΠΊΠ½ΠΈΠ³ΠΈ: Π±ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊΠ° ΠΈ Π±ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊΠ°Ρ€ΠΈ Π² ΠΌΠΈΡ€Π΅, Π³Π΄Π΅ мСняСтся всё

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    Transformation vectors for libraries as a social institution in the community based on digital information communications are examined. The necessity for changes is substantiated; library functions for the future are defined; ways of reforming are proposed.Π˜ΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½Ρ‹ направлСния прСобразования Π±ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊΠΈ ΠΊΠ°ΠΊ института Π² общСствС, построСнном Π½Π° систСмС Ρ†ΠΈΡ„Ρ€ΠΎΠ²Ρ‹Ρ… ΠΈΠ½Ρ„ΠΎΡ€ΠΌΠ°Ρ†ΠΈΠΎΠ½Π½Ρ‹Ρ… ΠΊΠΎΠΌΠΌΡƒΠ½ΠΈΠΊΠ°Ρ†ΠΈΠΉ. Обоснована Π½Π΅ΠΎΠ±Ρ…ΠΎΠ΄ΠΈΠΌΠΎΡΡ‚ΡŒ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΉ, ΠΎΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½Ρ‹ Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΈ Π±ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊ Π±ΡƒΠ΄ΡƒΡ‰Π΅Π³ΠΎ, ΠΏΡ€Π΅Π΄Π»ΠΎΠΆΠ΅Π½Ρ‹ ΠΏΡƒΡ‚ΠΈ Ρ€Π΅Π°Π»ΠΈΠ·Π°Ρ†ΠΈΠΈ Ρ€Π΅Ρ„ΠΎΡ€ΠΌ. ΠžΠ±Ρ€Π°Ρ‰Π΅Π½ΠΎ Π²Π½ΠΈΠΌΠ°Π½ΠΈΠ΅ Π½Π° Ρ‚ΠΎ, Ρ‡Ρ‚ΠΎ ΠΏΠΎΠ»ΠΈΡ‚ΠΈΠΊΠ° ΠΏΠΎΠ΄Π³ΠΎΡ‚ΠΎΠ²ΠΊΠΈ ΠΊΠ°Π΄Ρ€ΠΎΠ² для Π±ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊ нуТдаСтся Π² ΠΊΠΎΡ€Π΅Π½Π½ΠΎΠΌ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΈ: Π½Π΅ΠΎΠ±Ρ…ΠΎΠ΄ΠΈΠΌΠΎ ΠΏΠ΅Ρ€Π΅Ρ€Π°Π±Π°Ρ‚Ρ‹Π²Π°Ρ‚ΡŒ ΠΏΡ€ΠΎΡ„Π΅ΡΡΠΈΠΎΠ½Π°Π»ΡŒΠ½Ρ‹Π΅ стандарты, ΠΏΡ€ΠΎΠ³Ρ€Π°ΠΌΠΌΡ‹ обучСния Π² Π²Ρ‹ΡΡˆΠΈΡ… ΠΈ срСдних ΡƒΡ‡Π΅Π±Π½Ρ‹Ρ… завСдСниях. Π‘Π΄Π΅Π»Π°Π½ Π²Ρ‹Π²ΠΎΠ΄: Ρ„ΡƒΠ½Π΄Π°ΠΌΠ΅Π½Ρ‚ΠΎΠΌ прСобразования Π±ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊ ΡΠ²Π»ΡΡŽΡ‚ΡΡ Π±ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊΠ°Ρ€ΠΈ

    НовоС Π²ΠΈΠ΄Π΅Π½ΠΈΠ΅ Π±ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊΠΈ ΠΊΠ°ΠΊ ΡΠΎΡ†ΠΈΠ°Π»ΡŒΠ½ΠΎΠ³ΠΎ института Π² общСствС Π·Π½Π°Π½ΠΈΠΉ

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    The author offers a new paradigm of the library as a social institution in the period of the civilization transition from the information society to the knowledge society. The library functions and goals are defined, in particular encouraging and administering of free exchange of opinions and ideas between social strata and groups to solve their vital problems; providing space and tools (including acess to chargeable information content) to implement creative initiatives and to solve user everyday problems; designing training (educational) programs to adapt residents to continuously emerging innovations. Taking into account these new functions and tasks, the author defines the library as a social institution supporting cognitive and creative activities of the community being served through intellectual collaboration, educational and recreational programs, providing space, equipment hard- and software for public use and access to information sources.The author specifies the measures that would facilitate the RF libraries’ transition. He emphasizes that, to ensure success, the transformations are needed to be made both at the local (libraries) and at the federal level.ΠŸΡ€Π΅Π΄ΡΡ‚Π°Π²Π»Π΅Π½ΠΎ Π½ΠΎΠ²ΠΎΠ΅ Π²ΠΈΠ΄Π΅Π½ΠΈΠ΅ Π±ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊΠΈ ΠΊΠ°ΠΊ ΡΠΎΡ†ΠΈΠ°Π»ΡŒΠ½ΠΎΠ³ΠΎ института Π² условиях ΠΏΠ΅Ρ€Π΅Ρ…ΠΎΠ΄Π° Ρ†ΠΈΠ²ΠΈΠ»ΠΈΠ·Π°Ρ†ΠΈΠΈ ΠΎΡ‚ общСства ΠΈΠ½Ρ„ΠΎΡ€ΠΌΠ°Ρ†ΠΈΠΈ ΠΊ общСству Π·Π½Π°Π½ΠΈΠΉ. ΠžΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½Ρ‹ Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΈ ΠΈ Π·Π°Π΄Π°Ρ‡ΠΈ Π±ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊΠΈ. Π’ качСствС основных Π²Ρ‹Π΄Π΅Π»Π΅Π½Ρ‹: активизация ΠΈ ΠΌΠΎΠ΄Π΅Ρ€ΠΈΡ€ΠΎΠ²Π°Π½ΠΈΠ΅ свободного ΠΎΠ±ΠΌΠ΅Π½Π° идСями ΠΈ мнСниями ΠΌΠ΅ΠΆΠ΄Ρƒ слоями ΠΈ Π³Ρ€ΡƒΠΏΠΏΠ°ΠΌΠΈ сообщСства, Π½Π°ΠΏΡ€Π°Π²Π»Π΅Π½Π½ΠΎΠ΅ для Ρ€Π΅ΡˆΠ΅Π½ΠΈΡ ΠΈΡ… насущных ΠΏΡ€ΠΎΠ±Π»Π΅ΠΌ; прСдоставлСниС пространства ΠΈ инструмСнтария (Π²ΠΊΠ»ΡŽΡ‡Π°Ρ доступ ΠΊ ΠΏΠ»Π°Ρ‚Π½ΠΎΠΌΡƒ ΠΈΠ½Ρ„ΠΎΡ€ΠΌΠ°Ρ†ΠΈΠΎΠ½Π½ΠΎΠΌΡƒ наполнСнию) для Ρ€Π΅Π°Π»ΠΈΠ·Π°Ρ†ΠΈΠΈ творчСских ΠΈΠ½ΠΈΡ†ΠΈΠ°Ρ‚ΠΈΠ² ΠΈ Ρ€Π΅ΡˆΠ΅Π½ΠΈΡ повсСднСвных Π·Π°Π΄Π°Ρ‡ ΠΏΠΎΠ»ΡŒΠ·ΠΎΠ²Π°Ρ‚Π΅Π»Π΅ΠΉ; созданиС ΠΎΠ±ΡƒΡ‡Π°ΡŽΡ‰ΠΈΡ… (ΠΏΡ€ΠΎΡΠ²Π΅Ρ‚ΠΈΡ‚Π΅Π»ΡŒΡΠΊΠΈΡ…) ΠΏΡ€ΠΎΠ³Ρ€Π°ΠΌΠΌ, связанных с Π°Π΄Π°ΠΏΡ‚Π°Ρ†ΠΈΠ΅ΠΉ Π³Ρ€Π°ΠΆΠ΄Π°Π½ ΠΊ Π½Π΅ΠΏΡ€Π΅Ρ€Ρ‹Π²Π½ΠΎ ΠΏΠΎΡΠ²Π»ΡΡŽΡ‰ΠΈΠΌΡΡ ΠΈΠ½Π½ΠΎΠ²Π°Ρ†ΠΈΠΎΠ½Π½Ρ‹ΠΌ Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚ΠΊΠ°ΠΌ. Π‘ ΡƒΡ‡Ρ‘Ρ‚ΠΎΠΌ Π½ΠΎΠ²Ρ‹Ρ… Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΉ ΠΈ Π·Π°Π΄Π°Ρ‡ Π΄Π°Π½ΠΎ Π½ΠΎΠ²ΠΎΠ΅ ΠΎΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ Π±ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊΠΈ: ΡΠΎΡ†ΠΈΠ°Π»ΡŒΠ½Ρ‹ΠΉ институт, ΠΎΠ±Π΅ΡΠΏΠ΅Ρ‡ΠΈΠ²Π°ΡŽΡ‰ΠΈΠΉ ΠΏΠΎΠ·Π½Π°Π²Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎ-Ρ‚Π²ΠΎΡ€Ρ‡Π΅ΡΠΊΡƒΡŽ Π΄Π΅ΡΡ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΡŒ обслуТиваСмого сообщСства посрСдством ΠΎΡ€Π³Π°Π½ΠΈΠ·Π°Ρ†ΠΈΠΈ ΠΈΠ½Ρ‚Π΅Π»Π»Π΅ΠΊΡ‚ΡƒΠ°Π»ΡŒΠ½ΠΎΠ³ΠΎ взаимодСйствия, Ρ€Π΅Π°Π»ΠΈΠ·Π°Ρ†ΠΈΠΈ ΠΎΠ±ΡƒΡ‡Π°ΡŽΡ‰ΠΈΡ… ΠΈ досуговых ΠΏΡ€ΠΎΠ³Ρ€Π°ΠΌΠΌ, прСдоставлСния Π² общСствСнноС пользованиС Π½Π΅ΠΎΠ±Ρ…ΠΎΠ΄ΠΈΠΌΠΎΠ³ΠΎ пространства, Π°ΠΏΠΏΠ°Ρ€Π°Ρ‚Π½ΠΎΠ³ΠΎ ΠΈ ΠΏΡ€ΠΎΠ³Ρ€Π°ΠΌΠΌΠ½ΠΎΠ³ΠΎ инструмСнтария ΠΈ доступа ΠΊ источникам ΠΈΠ½Ρ„ΠΎΡ€ΠΌΠ°Ρ†ΠΈΠΈ.ΠŸΡ€ΠΈΠ²Π΅Π΄Ρ‘Π½ ΠΏΠ΅Ρ€Π΅Ρ‡Π΅Π½ΡŒ ΠΌΠ΅Ρ€, ΠΎΠ±Π΅ΡΠΏΠ΅Ρ‡ΠΈΠ²Π°ΡŽΡ‰ΠΈΡ… ΠΏΠ΅Ρ€Π΅Ρ…ΠΎΠ΄ Π±ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊ Российской Π€Π΅Π΄Π΅Ρ€Π°Ρ†ΠΈΠΈ Π½Π° качСствСнно ΠΈΠ½ΠΎΠΉ этап развития. ΠžΡ‚ΠΌΠ΅Ρ‡Π΅Π½ΠΎ, Ρ‡Ρ‚ΠΎ для достиТСния успСха прСобразования Π΄ΠΎΠ»ΠΆΠ½Ρ‹ ΠΎΡΡƒΡ‰Π΅ΡΡ‚Π²Π»ΡΡ‚ΡŒΡΡ ΠΎΠ΄Π½ΠΎΠ²Ρ€Π΅ΠΌΠ΅Π½Π½ΠΎ снизу (ΡƒΡ€ΠΎΠ²Π΅Π½ΡŒ ΠΊΠΎΠ½ΠΊΡ€Π΅Ρ‚Π½Ρ‹Ρ… Π±ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊ) ΠΈ свСрху (Ρ„Π΅Π΄Π΅Ρ€Π°Π»ΡŒΠ½Ρ‹ΠΉ ΡƒΡ€ΠΎΠ²Π΅Π½ΡŒ)

    Π‘ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊΠ° ΠΈ Π±ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊΠ°Ρ€ΠΈ Π² блиТайшиС Π΄Π²Π°Π΄Ρ†Π°Ρ‚ΡŒ Π»Π΅Ρ‚, ΠΈΠ»ΠΈ Π’ ΠΎΠΆΠΈΠ΄Π°Π½ΠΈΠΈ сингулярности

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    Libraries’ functions in the era of digital communications are defined; the need for fundamentally new approach toward library services to reflect digital society demands is substantiated. The author concludes that, in the radically new circumstances, libraries will offer complex of user-oriented services relevant to the society’s interests. The libraries will cease to be institutions for document arrays acquisition, storage and delivery for public use, and become the open innovative and education sites to support every form of gaining knowledge and competences enabling users to adapt to continuously changing environment. The author suggests several measures to preserve the social institution of libraries in the circumstances of high technologies exponential growth. The author emphasizes that the libraries’ task is to organize and to hold lectures, trainings, workshops, discussions to motivate knowledge gaining, to widen horizons and develop users’ critical thinking. With these activities, the libraries will convert into intellectual center, improve their reputation and increase their role considerably. The author also argues that changes in library functions will inevitably result in transformed library structure and space. The importance of interaction with the user groups is emphasized.ΠžΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½Ρ‹ Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΈ Π±ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊΠΈ эпохи Ρ†ΠΈΡ„Ρ€ΠΎΠ²Ρ‹Ρ… ΠΊΠΎΠΌΠΌΡƒΠ½ΠΈΠΊΠ°Ρ†ΠΈΠΉ; Π°Ρ€Π³ΡƒΠΌΠ΅Π½Ρ‚ΠΈΡ€ΠΎΠ²Π°Π½Π° Π½Π΅ΠΎΠ±Ρ…ΠΎΠ΄ΠΈΠΌΠΎΡΡ‚ΡŒ внСдрСния ΠΏΡ€ΠΈΠ½Ρ†ΠΈΠΏΠΈΠ°Π»ΡŒΠ½ΠΎ ΠΈΠ½Ρ‹Ρ… ΠΏΠΎΠ΄Ρ…ΠΎΠ΄ΠΎΠ² ΠΊ Π΄Π΅ΡΡ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΠΈ Π±ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊΠΈ, обусловлСнных потрСбностями Π³Ρ€Π°ΠΆΠ΄Π°Π½ Ρ†ΠΈΡ„Ρ€ΠΎΠ²ΠΎΠ³ΠΎ общСства. Π‘Π΄Π΅Π»Π°Π½ Π²Ρ‹Π²ΠΎΠ΄ ΠΎ Ρ‚ΠΎΠΌ, Ρ‡Ρ‚ΠΎ Π² ΠΊΠ°Ρ€Π΄ΠΈΠ½Π°Π»ΡŒΠ½ΠΎ ΠΈΠ·ΠΌΠ΅Π½ΠΈΠ²ΡˆΠΈΡ…ΡΡ условиях Π±ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊΠ° ΠΏΡ€ΠΈΠ·Π²Π°Π½Π° ΠΏΡ€Π΅Π΄ΠΎΡΡ‚Π°Π²Π»ΡΡ‚ΡŒ Π°Π΄Π΅ΠΊΠ²Π°Ρ‚Π½ΡƒΡŽ интСрСсам общСства ΡΠΎΠ²ΠΎΠΊΡƒΠΏΠ½ΠΎΡΡ‚ΡŒ сСрвисов, ΠΎΡ€ΠΈΠ΅Π½Ρ‚ΠΈΡ€ΠΎΠ²Π°Π½Π½Ρ‹Ρ… Π½Π° ΡƒΠ΄ΠΎΠ²Π»Π΅Ρ‚Π²ΠΎΡ€Π΅Π½ΠΈΠ΅ потрСбностСй Π³Ρ€Π°ΠΆΠ΄Π°Π½. Из учрСТдСния, Π·Π°Π½ΠΈΠΌΠ°ΡŽΡ‰Π΅Π³ΠΎΡΡ сбором, Ρ…Ρ€Π°Π½Π΅Π½ΠΈΠ΅ΠΌ ΠΈ прСдоставлСниСм Π² общСствСнноС использованиС Π΄ΠΎΠΊΡƒΠΌΠ΅Π½Ρ‚Π½ΠΎΠ³ΠΎ массива, Π±ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊΠ° Π΄ΠΎΠ»ΠΆΠ½Π° ΠΏΡ€Π΅Π²Ρ€Π°Ρ‚ΠΈΡ‚ΡŒΡΡ Π² ΠΎΡ‚ΠΊΡ€Ρ‹Ρ‚ΡƒΡŽ ΠΈΠ½Π½ΠΎΠ²Π°Ρ†ΠΈΠΎΠ½Π½ΠΎ-ΠΏΡ€ΠΎΡΠ²Π΅Ρ‚ΠΈΡ‚Π΅Π»ΡŒΡΠΊΡƒΡŽ ΠΏΠ»ΠΎΡ‰Π°Π΄ΠΊΡƒ, ΠΎΠ±Π΅ΡΠΏΠ΅Ρ‡ΠΈΠ²Π°ΡŽΡ‰ΡƒΡŽ ΠΏΠΎΠ΄Π΄Π΅Ρ€ΠΆΠΊΡƒ всСх Ρ„ΠΎΡ€ΠΌ познания ΠΈ обрСтСния ΠΏΠΎΠ»ΡŒΠ·ΠΎΠ²Π°Ρ‚Π΅Π»ΡΠΌΠΈ ΠΊΠΎΠΌΠΏΠ΅Ρ‚Π΅Π½Ρ†ΠΈΠΉ, ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Π΅ ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡŽΡ‚ Π°Π΄Π°ΠΏΡ‚ΠΈΡ€ΠΎΠ²Π°Ρ‚ΡŒΡΡ ΠΊ постоянно ΠΌΠ΅Π½ΡΡŽΡ‰ΠΈΠΌΡΡ условиям ΠΆΠΈΠ·Π½ΠΈ. ΠŸΡ€ΠΈΠ²Π΅Π΄Ρ‘Π½ ΠΏΠ΅Ρ€Π΅Ρ‡Π΅Π½ΡŒ ΠΌΠ΅Ρ€, ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Π΅ слСдуСт ΠΏΡ€Π΅Π΄ΠΏΡ€ΠΈΠ½ΡΡ‚ΡŒ для сохранСния Π±ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊΠΈ ΠΊΠ°ΠΊ общСствСнного института Π² условиях ΡΠΊΡΠΏΠΎΠ½Π΅Π½Ρ†ΠΈΠ°Π»ΡŒΠ½ΠΎΠ³ΠΎ развития высоких Ρ‚Π΅Ρ…Π½ΠΎΠ»ΠΎΠ³ΠΈΠΉ. Π‘Π΄Π΅Π»Π°Π½ Π°ΠΊΡ†Π΅Π½Ρ‚ Π½Π° Ρ‚ΠΎΠΌ, Ρ‡Ρ‚ΠΎ Π·Π°Π΄Π°Ρ‡Π° Π±ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊΠΈ - организация Π»Π΅ΠΊΡ†ΠΈΠΉ, Ρ‚Ρ€Π΅Π½ΠΈΠ½Π³ΠΎΠ², сСминаров, дискуссий, ΡΡ‚ΠΈΠΌΡƒΠ»ΠΈΡ€ΡƒΡŽΡ‰ΠΈΡ… ΠΎΠ±Ρ€Π΅Ρ‚Π΅Π½ΠΈΠ΅ Π·Π½Π°Π½ΠΈΠΉ ΠΈ Π½Π°Π²Ρ‹ΠΊΠΎΠ², Ρ€Π°Π·Π²ΠΈΡ‚ΠΈΠ΅ ΠΊΡ€ΡƒΠ³ΠΎΠ·ΠΎΡ€Π° ΠΈ критичСского ΠΌΡ‹ΡˆΠ»Π΅Π½ΠΈΡ ΠΏΠΎΠ»ΡŒΠ·ΠΎΠ²Π°Ρ‚Π΅Π»Π΅ΠΉ. Π­Ρ‚Π° Π΄Π΅ΡΡ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΡŒ ΠΏΡ€Π΅Π²Ρ€Π°Ρ‰Π°Π΅Ρ‚ Π±ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊΡƒ Π² ΠΏΠΎΠ΄Π»ΠΈΠ½Π½Ρ‹ΠΉ Ρ†Π΅Π½Ρ‚Ρ€ ΠΈΠ½Ρ‚Π΅Π»Π»Π΅ΠΊΡ‚ΡƒΠ°Π»ΡŒΠ½ΠΎΠΉ ΠΆΠΈΠ·Π½ΠΈ общСства, качСствСнно ΠΏΠΎΠ²Ρ‹ΡˆΠ°Π΅Ρ‚ Π΅Ρ‘ Π·Π½Π°Ρ‡Π΅Π½ΠΈΠ΅ ΠΈ Π°Π²Ρ‚ΠΎΡ€ΠΈΡ‚Π΅Ρ‚. ΠŸΠΎΠ΄Ρ‡Ρ‘Ρ€ΠΊΠ½ΡƒΡ‚ΠΎ, Ρ‡Ρ‚ΠΎ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΉ Π·Π°ΠΊΠΎΠ½ΠΎΠΌΠ΅Ρ€Π½ΠΎ ΠΏΡ€ΠΈΠ²Π΅Π΄Ρ‘Ρ‚ ΠΊ Ρ€Π΅ΠΎΡ€Π³Π°Π½ΠΈΠ·Π°Ρ†ΠΈΠΈ структуры ΠΈ пространства Π±ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊΠΈ; ΠΎΡ‚ΠΌΠ΅Ρ‡Π΅Π½Π° Π²Π°ΠΆΠ½ΠΎΡΡ‚ΡŒ взаимодСйствия с ΠΏΠΎΠ»ΡŒΠ·ΠΎΠ²Π°Ρ‚Π΅Π»ΡŒΡΠΊΠΈΠΌΠΈ Π³Ρ€ΡƒΠΏΠΏΠ°ΠΌΠΈ

    Frequencies of alleles, genotypes and haplotypes of two polymorphisms in the clusterin gene in the Russian elderly population categorized by cognitive performance

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    This article contains data on the frequencies of alleles, genotypes and haplotypes of the single nucleotide polymorphisms (SNPs) rs2279590 and rs1532278 in the CLU gene in a cohort of normal elderly from the Russian population. The SNPs have been reported to be associated with Alzheimer's disease and cognitive functions in genome-wide and candidate genes association studies. Cognitive performance in sample set was estimated by the Montreal Cognitive Assessment (MoCA). The frequencies of alleles, genotypes and haplotypes of two SNPs were calculated in 3 groups: total sample set, sample set with MoCA score less than 21 (the first quartile) and group with MoCA score more than 24 (the fourth quartile)

    Between Lake Baikal and the Baltic Sea: Genomic History of the Gateway to Europe

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    Background: The history of human populations occupying the plains and mountain ridges separating Europe from Asia has been eventful, as these natural obstacles were crossed westward by multiple waves of Turkic and Uralic speaking migrants as well as eastward by Europeans. Unfortunately, the material records of history of this region are not dense enough to reconstruct details of population history. These considerations stimulate growing interest to obtain a genetic picture of the demographic history of migrations and admixture in Northern Eurasia. Results: We genotyped and analyzed 1076 individuals from 30 populations with geographical coverage spanning from Baltic Sea to Baikal Lake. Our dense sampling allowed us to describe in detail the population structure, provide insight into genomic history of numerous European and Asian populations, and significantly increase quantity of genetic data available for modern populations in region of North Eurasia. Our study doubles the amount of genome-wide profiles available for this region. We detected unusually high amount of shared identical-by-descent (IBD) genomic segments between several Siberian populations, such as Khanty and Ket, providing evidence of genetic relatedness across vast geographic distances and between speakers of different language families. Additionally, we observed excessive IBD sharing between Khanty and Bashkir, a group of Turkic speakers from Southern Urals region. While adding some weight to the β€œFinno-Ugric” origin of Bashkir, our studies highlighted that the Bashkir genepool lacks the main β€œcore”, being a multi-layered amalgamation of Turkic, Ugric, Finnish and Indo-European contributions, which points at intricacy of genetic interface between Turkic and Uralic populations. Comparison of the genetic structure of Siberian ethnicities and the geography of the region they inhabit point at existence of the β€œGreat Siberian Vortex” directing genetic exchanges in populations across the Siberian part of Asia. Slavic speakers of Eastern Europe are, in general, very similar in their genetic composition. Ukrainians, Belarusians and Russians have almost identical proportions of Caucasus and Northern European components and have virtually no Asian influence. We capitalized on wide geographic span of our sampling to address intriguing question about the place of origin of Russian Starovers, an enigmatic Eastern Orthodox Old Believers religious group relocated to Siberia in seventeenth century. A comparative reAdmix analysis, complemented by IBD sharing, placed their roots in the region of the Northern European Plain, occupied by North Russians and Finno-Ugric Komi and Karelian people. Russians from Novosibirsk and Russian Starover exhibit ancestral proportions close to that of European Eastern Slavs, however, they also include between five to 10 % of Central Siberian ancestry, not present at this level in their European counterparts. Conclusions: Our project has patched the hole in the genetic map of Eurasia: we demonstrated complexity of genetic structure of Northern Eurasians, existence of East-West and North-South genetic gradients, and assessed different inputs of ancient populations into modern populations

    ДослідТСння Π΅ΠΊΠΎΠ»ΠΎΠ³Ρ–Ρ‡Π½ΠΎ Π±Π΅Π·ΠΏΠ΅Ρ‡Π½ΠΎΠ³ΠΎ одСрТання молібдСнвмісної Π»Π΅Π³ΡƒΡŽΡ‡ΠΎΡ— сировини способом Ρ‚Π²Π΅Ρ€Π΄ΠΎΡ„Π°Π·Π½ΠΎΠ³ΠΎ відновлСння

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    The study has determined an increase of the degree of thermal carbon extraction of the molybdenum oxide concentrate from 11Β % to 97Β % with an increase in the processing temperature from 873Β K to 1373Β K, respectively. A further rise in temperature to 1473Β K led to a reduction in the degree of recovery to 89Β %. The recovery products after treatment at 873–1073Β K mostly consisted of MoO2 with some Mo and Mo2C manifestations. Treatment at 1223–1473Β K provided a predominance of Mo and Mo2C as to the oxide component. The microstructure of the recovery products was spongy and disordered with varying degrees of sintering, depending on the processing temperature. The alloying of R6M5 steel with the new molybdenum material in experimental industrial conditions provided an increase in the Mo uptake rate from 88.9Β % to 95.0Β % compared with the standard technology. Improvement of environmental safety is achieved by replacing carbon monoxide and aluminothermic melting of ferroalloy production of Mo with the latest methods of powder metallurgy.ΠžΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½Ρ‹ кинСтичСскиС закономСрности углСродотСрмичСского восстановлСния оксидного ΠΌΠΎΠ»ΠΈΠ±Π΄Π΅Π½ΠΎΠ²ΠΎΠ³ΠΎ ΠΊΠΎΠ½Ρ†Π΅Π½Ρ‚Ρ€Π°Ρ‚Π° Π² ΠΈΠ½Ρ‚Π΅Ρ€Π²Π°Π»Π΅ 873–1473 K. Наибольшая ΡΡ‚Π΅ΠΏΠ΅Π½ΡŒ восстановлСния 97 % достигнута послС ΠΎΠ±Ρ€Π°Π±ΠΎΡ‚ΠΊΠΈ ΠΏΡ€ΠΈ 1373 K с ΠΏΡ€Π΅ΠΎΠ±Π»Π°Π΄Π°Π½ΠΈΠ΅ΠΌ Π² Ρ„Π°Π·ΠΎΠ²ΠΎΠΌ составС Mo. ΠœΠΈΠΊΡ€ΠΎΡΡ‚Ρ€ΡƒΠΊΡ‚ΡƒΡ€Π° – губчатая разупорядочСнная. Π£Π»ΡƒΡ‡ΡˆΠ΅Π½ΠΈΠ΅ экологичСской бСзопасности достигаСтся Π·Π°ΠΌΠ΅Π½ΠΎΠΉ углСродосилико- ΠΈ Π°Π»ΡŽΠΌΠΎΡ‚Π΅Ρ€ΠΌΠΈΡ‡Π΅ΡΠΊΠΎΠΉ ΠΏΠ»Π°Π²ΠΎΠΊ фСрросплавного производства Mo Π½Π° новСйшиС ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹ ΠΏΠΎΡ€ΠΎΡˆΠΊΠΎΠ²ΠΎΠΉ ΠΌΠ΅Ρ‚Π°Π»Π»ΡƒΡ€Π³ΠΈΠΈΠ’ΠΈΠ·Π½Π°Ρ‡Π΅Π½ΠΎ ΠΊΡ–Π½Π΅Ρ‚ΠΈΡ‡Π½Ρ– закономірності Π²ΡƒΠ³Π»Π΅Ρ†Π΅Π²ΠΎΡ‚Π΅Ρ€ΠΌΡ–Ρ‡Π½ΠΎΠ³ΠΎ відновлСння оксидного ΠΌΠΎΠ»Ρ–Π±Π΄Π΅Π½ΠΎΠ²ΠΎΠ³ΠΎ ΠΊΠΎΠ½Ρ†Π΅Π½Ρ‚Ρ€Π°Ρ‚Ρƒ Π² Ρ–Π½Ρ‚Π΅Ρ€Π²Π°Π»Ρ– 873–1473 K. Найвищий ΡΡ‚ΡƒΠΏΡ–Π½ΡŒ відновлСння 97 % досягнуто після ΠΎΠ±Ρ€ΠΎΠ±ΠΊΠΈ ΠΏΡ€ΠΈ 1373 K Ρ–Π· пСрСваТанням Ρƒ Ρ„Π°Π·ΠΎΠ²ΠΎΠΌΡƒ складі Mo. ΠœΡ–ΠΊΡ€ΠΎΡΡ‚Ρ€ΡƒΠΊΡ‚ΡƒΡ€Π° – губчаста розупорядкована. ΠŸΠΎΠ»Ρ–ΠΏΡˆΠ΅Π½Π½Ρ Π΅ΠΊΠΎΠ»ΠΎΠ³Ρ–Ρ‡Π½ΠΎΡ— Π±Π΅Π·ΠΏΠ΅ΠΊΠΈ Π΄ΠΎΡΡΠ³Π°Ρ”Ρ‚ΡŒΡΡ Π·Π°ΠΌΡ–Π½ΠΎΡŽ вуглСцСвосиліко- Ρ‚Π° Π°Π»ΡŽΠΌΠΎΡ‚Π΅Ρ€ΠΌΡ–Ρ‡Π½ΠΎΡ— ΠΏΠ»Π°Π²ΠΎΠΊ фСросплавного Π²ΠΈΡ€ΠΎΠ±Π½ΠΈΡ†Ρ‚Π²Π° Mo Π½Π° Π½ΠΎΠ²Ρ–Ρ‚Π½Ρ– ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΈ ΠΏΠΎΡ€ΠΎΡˆΠΊΠΎΠ²ΠΎΡ— ΠΌΠ΅Ρ‚Π°Π»ΡƒΡ€Π³Ρ–

    Simulation of blue light leds in Comsol Multiphysics

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    The process of modeling the LEDs of the blue spectrum of radiation was been investigated, and the correlation of results with experiment.ИсслСдован процСсс модСлирования свСтодиодов синСго Π΄ΠΈΠ°ΠΏΠ°Π·ΠΎΠ½Π° ΠΈ коррСляция ΠΏΠΎΠ»ΡƒΡ‡Π΅Π½Π½Ρ‹Ρ… Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚ΠΎΠ² с экспСримСнтом

    Simulation of high-efficiency leds in Comsol Multiphysics

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    The model of high-efficiency LEDs with double heterostructure was realized in Comsol Multiphysics.Π Π΅Π°Π»ΠΈΠ·ΠΎΠ²Π°Π½Π° модСль ΡΠ²Π΅Ρ‚ΠΎΠΈΠ·Π»ΡƒΡ‡Π°ΡŽΡ‰Π΅Π³ΠΎ Π΄ΠΈΠΎΠ΄Π° с Π΄Π²ΠΎΠΉΠ½ΠΎΠΉ гСтСроструктурой Π² ΠΏΡ€ΠΎΠ³Ρ€Π°ΠΌΠΌΠ½ΠΎΠΌ ΠΏΠ°ΠΊΠ΅Ρ‚Π΅ Comsol Multiphysics
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