56 research outputs found
Gravitational Lensing by Black Holes
We review the theoretical aspects of gravitational lensing by black holes,
and discuss the perspectives for realistic observations. We will first treat
lensing by spherically symmetric black holes, in which the formation of
infinite sequences of higher order images emerges in the clearest way. We will
then consider the effects of the spin of the black hole, with the formation of
giant higher order caustics and multiple images. Finally, we will consider the
perspectives for observations of black hole lensing, from the detection of
secondary images of stellar sources and spots on the accretion disk to the
interpretation of iron K-lines and direct imaging of the shadow of the black
hole.Comment: Invited article for the GRG special issue on lensing (P. Jetzer, Y.
Mellier and V. Perlick Eds.). 31 pages, 12 figure
Very-high energy gamma-ray astronomy: A 23-year success story in high-energy astroparticle physics
Very-high energy (VHE) gamma quanta contribute only a minuscule fraction -
below one per million - to the flux of cosmic rays. Nevertheless, being neutral
particles they are currently the best "messengers" of processes from the
relativistic/ultra-relativistic Universe because they can be extrapolated back
to their origin. The window of VHE gamma rays was opened only in 1989 by the
Whipple collaboration, reporting the observation of TeV gamma rays from the
Crab nebula. After a slow start, this new field of research is now rapidly
expanding with the discovery of more than 150 VHE gamma-ray emitting sources.
Progress is intimately related with the steady improvement of detectors and
rapidly increasing computing power. We give an overview of the early attempts
before and around 1989 and the progress after the pioneering work of the
Whipple collaboration. The main focus of this article is on the development of
experimental techniques for Earth-bound gamma-ray detectors; consequently, more
emphasis is given to those experiments that made an initial breakthrough rather
than to the successors which often had and have a similar (sometimes even
higher) scientific output as the pioneering experiments. The considered energy
threshold is about 30 GeV. At lower energies, observations can presently only
be performed with balloon or satellite-borne detectors. Irrespective of the
stormy experimental progress, the success story could not have been called a
success story without a broad scientific output. Therefore we conclude this
article with a summary of the scientific rationales and main results achieved
over the last two decades.Comment: 45 pages, 38 figures, review prepared for EPJ-H special issue "Cosmic
rays, gamma rays and neutrinos: A survey of 100 years of research
Magnetic Field Generation in Stars
Enormous progress has been made on observing stellar magnetism in stars from
the main sequence through to compact objects. Recent data have thrown into
sharper relief the vexed question of the origin of stellar magnetic fields,
which remains one of the main unanswered questions in astrophysics. In this
chapter we review recent work in this area of research. In particular, we look
at the fossil field hypothesis which links magnetism in compact stars to
magnetism in main sequence and pre-main sequence stars and we consider why its
feasibility has now been questioned particularly in the context of highly
magnetic white dwarfs. We also review the fossil versus dynamo debate in the
context of neutron stars and the roles played by key physical processes such as
buoyancy, helicity, and superfluid turbulence,in the generation and stability
of neutron star fields.
Independent information on the internal magnetic field of neutron stars will
come from future gravitational wave detections. Thus we maybe at the dawn of a
new era of exciting discoveries in compact star magnetism driven by the opening
of a new, non-electromagnetic observational window.
We also review recent advances in the theory and computation of
magnetohydrodynamic turbulence as it applies to stellar magnetism and dynamo
theory. These advances offer insight into the action of stellar dynamos as well
as processes whichcontrol the diffusive magnetic flux transport in stars.Comment: 41 pages, 7 figures. Invited review chapter on on magnetic field
generation in stars to appear in Space Science Reviews, Springe
Phenomenology of the Lense-Thirring effect in the Solar System
Recent years have seen increasing efforts to directly measure some aspects of
the general relativistic gravitomagnetic interaction in several astronomical
scenarios in the solar system. After briefly overviewing the concept of
gravitomagnetism from a theoretical point of view, we review the performed or
proposed attempts to detect the Lense-Thirring effect affecting the orbital
motions of natural and artificial bodies in the gravitational fields of the
Sun, Earth, Mars and Jupiter. In particular, we will focus on the evaluation of
the impact of several sources of systematic uncertainties of dynamical origin
to realistically elucidate the present and future perspectives in directly
measuring such an elusive relativistic effect.Comment: LaTex, 51 pages, 14 figures, 22 tables. Invited review, to appear in
Astrophysics and Space Science (ApSS). Some uncited references in the text
now correctly quoted. One reference added. A footnote adde
Gene-gene Interaction Analyses for Atrial Fibrillation
Atrial fibrillation (AF) is a heritable disease that affects more than thirty million individuals worldwide. Extensive efforts have been devoted to the study of genetic determinants of AF. The objective of our study is to examine the effect of gene-gene interaction on AF susceptibility. We performed a large-scale association analysis of gene-gene interactions with AF in 8,173 AF cases, and 65,237 AF-free referents collected from 15 studies for discovery. We examined putative interactions between genome-wide SNPs and 17 known AF-related SNPs. The top interactions were then tested for association in a
A Measurement of the Proton Structure Function
A measurement of the proton structure function is reported
for momentum transfer squared between 4.5 and 1600 and
for Bjorken between and 0.13 using data collected by the
HERA experiment H1 in 1993. It is observed that increases
significantly with decreasing , confirming our previous measurement made
with one tenth of the data available in this analysis. The dependence is
approximately logarithmic over the full kinematic range covered. The subsample
of deep inelastic events with a large pseudo-rapidity gap in the hadronic
energy flow close to the proton remnant is used to measure the "diffractive"
contribution to .Comment: 32 pages, ps, appended as compressed, uuencoded fil
Stretching and immobilization of DNA for studies of protein–DNA interactions at the single-molecule level
Whole-genome sequencing reveals host factors underlying critical COVID-19
Critical COVID-19 is caused by immune-mediated inflammatory lung injury. Host genetic variation influences the development of illness requiring critical care1 or hospitalization2,3,4 after infection with SARS-CoV-2. The GenOMICC (Genetics of Mortality in Critical Care) study enables the comparison of genomes from individuals who are critically ill with those of population controls to find underlying disease mechanisms. Here we use whole-genome sequencing in 7,491 critically ill individuals compared with 48,400 controls to discover and replicate 23 independent variants that significantly predispose to critical COVID-19. We identify 16 new independent associations, including variants within genes that are involved in interferon signalling (IL10RB and PLSCR1), leucocyte differentiation (BCL11A) and blood-type antigen secretor status (FUT2). Using transcriptome-wide association and colocalization to infer the effect of gene expression on disease severity, we find evidence that implicates multiple genes—including reduced expression of a membrane flippase (ATP11A), and increased expression of a mucin (MUC1)—in critical disease. Mendelian randomization provides evidence in support of causal roles for myeloid cell adhesion molecules (SELE, ICAM5 and CD209) and the coagulation factor F8, all of which are potentially druggable targets. Our results are broadly consistent with a multi-component model of COVID-19 pathophysiology, in which at least two distinct mechanisms can predispose to life-threatening disease: failure to control viral replication; or an enhanced tendency towards pulmonary inflammation and intravascular coagulation. We show that comparison between cases of critical illness and population controls is highly efficient for the detection of therapeutically relevant mechanisms of disease
Gender role stereotypes and requisite management characteristics : the case of South Africa
PURPOSE: Although Schein’s gender role management stereotype hypothesis has been examined in many countries around the world, no studies specifically examine the combined effects of race and gender on this phenomenon. The purpose of this paper is to use an intersectional analysis to test the hypothesis among different race and gender groups in South Africa.
DESIGN/METHODOLOGY/APPROACH: The 92-item Schein descriptive index was randomly administered to 592 black men, white men, black women, and white women managers. The degree of resemblance between the descriptions of men and successful managers and between women and successful managers was determined by computing intra-class correlation coefficients.
FINDINGS: Results confirm the think manager, think male hypothesis for black and white men but not for black and white women. Black and white men are less likely to attribute successful managerial characteristics to women. The hypothesis is more robust among black men than among white men. For black women, the resemblance between the characteristics of women in general and successful managers is significantly higher than the resemblance of men in general and successful managers. This represents only the second study globally to report a reversal of the usual pattern. White women perceived men and women to equally possess the requisite management characteristics.
PRACTICAL IMPLICATIONS: Intersectionality is capable of revealing the ways in which race and gender simultaneously influence perceptions of managerial characteristics.
ORIGINALITY/VALUE: The paper provides a race and gender intersectional analysis that compares the perceptions of the think manager – think male hypothesis in contrast to the dominant gender only
analysis that may mask important differences in the stereotyping of managerial characteristics. It is also the first study of its kind in South Africa
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