Returns to education in West Germany: an empirical assessment

This paper analyses the developments in the returns to education in West Germany for the period from 1984 to 1997. Based on simple Mincer-type wage equations, we estimate a return of about 8% for men and 10% for women, and these returns have remained remarkably stable over the period. On the basis of more differentiated specifications of wage equations, we find evidence for the presence of cohort effects, in addition to time and lifecycle effects. Furthermore, the analysis shows that the choice of the sample of observation plays a crucial role. Indeed, huge differences exist between part-timers and full-timers, as well as between private and public sectors. Full-time working women have similar returns to schooling than men, and if female returns are declining and have become lower than male returns in the private sector, they are rather increasing and are higher than male ones in the public sector. Moreover, not all education degrees yield the same annual return. If one accounts for the different lengths of studies, the master craftsman degree yields the highest return. However, the estimates proved rather robust towards the specification of the wage equation and the estimation method. --

Returns to Education in West Germany : An Empirical Assessment

This paper analyses the developments in the returns to education in West Germany for the period from 1984 to 1997. Based on simple Mincer-type wage equations, we estimate a return of about 8% for men and 10% for women, and these returns have remained remarkably stable over the period. On the basis of more differentiated specifications of wage equations, we find evidence for the presence of cohort effects, in addition to time and lifecycle effects. Furthermore, the analysis shows that the choice of the sample of observation plays a crucial role. Indeed, huge differences exist between part-timers and full-timers, as well as between private and public sectors. Full-time working women have similar returns to schooling than men, and if female returns are declining and have become lower than male returns in the private sector, they are rather increasing and are higher than male ones in the public sector. Moreover, not all education degrees yield the same annual return. If one accounts for the different lengths of studies, the master craftsman degree yields the highest return. However, the estimates proved rather robust towards the specification of the wage equation and the estimation method

Private Erträge von Bildungsinvestitionen in Deutschland

Wir analysieren die Entwicklung der Bildungsrenditen in Westdeutschland in der Periode von 1984 bis 1997 auf der Basis der Humankapitaltheorie mit Daten des Sozio-Ökonomischen Panels. Die Schätzergebnisse zeigen, dass Frauen mit etwa 10% eine signifikant höhere durchschnittliche Bildungsrendite erzielen als Männer mit etwa 8%. Diese durchschnittlichen Renditen sind über den Beobachtungszeitraum weitgehend stabil geblieben. Die Schätzergebnisse sind relativ robust gegenüber unterschiedlichen Spezifikationen der Bildungsvariable und der Schätzmethode. Differenziertere Analysen zeigen, dass die Bildungsrenditen jüngerer Geburtskohorten insbesondere bei den Frauen deutlich gesunken sind. Wir diskutieren den Einfluss von Kohorten-, Lebenszyklus- und Kalenderzeiteffekten auf diese Entwicklung, analysieren Unterschiede in den Bildungsrenditen zwischen Vollzeit- und Teilzeitbeschäftigten sowie zwischen öffentlichem Dienst und privatem Sektor der Wirtschaft und vergleichen die für Deutschland geschätzten Bildungsrenditen mit den für die anderen Mitgliedstaaten der Europäischen Union berechneten

Private Erträge von Bildungsinvestitionen in Deutschland

Wir analysieren die Entwicklung der Bildungsrenditen in Westdeutschland in der Periode von 1984 bis 1997 auf der Basis der Humankapitaltheorie mit Daten des Sozio-Ökonomischen Panels. Die Schätzergebnisse zeigen, dass Frauen mit etwa 10% eine signifikant höhere durchschnittliche Bildungsrendite erzielen als Männer mit etwa 8%. Diese durchschnittlichen Renditen sind über den Beobachtungszeitraum weitgehend stabil geblieben. Die Schätzergebnisse sind relativ robust gegenüber unterschiedlichen Spezifikationen der Bildungsvariable und der Schätzmethode. Differenziertere Analysen zeigen, dass die Bildungsrenditen jüngerer Geburtskohorten insbesondere bei den Frauen deutlich gesunken sind. Wir diskutieren den Einfluss von Kohorten-, Lebenszyklus- und Kalenderzeiteffekten auf diese Entwicklung, analysieren Unterschiede in den Bildungsrenditen zwischen Vollzeit- und Teilzeitbeschäftigten sowie zwischen öffentlichem Dienst und privatem Sektor der Wirtschaft und vergleichen die für Deutschland geschätzten Bildungsrenditen mit den für die anderen Mitgliedstaaten der Europäischen Union berechneten --

Only watching others making their experiences is insufficient to enhance adult neurogenesis and water maze performance in mice

In the context of television consumption and its opportunity costs the question arises how far experiencing mere representations of the outer world would have the same neural and cognitive consequences than actively interacting with that environment. Here we demonstrate that physical interaction and direct exposition are essential for the beneficial effects of environmental enrichment. In our experiment, the mice living in a simple standard cage placed in the centre of a large enriched environment only indirectly experiencing the stimulus-rich surroundings (IND) did not display increased adult hippocampal neurogenesis. In contrast, the mice living in and directly experiencing the surrounding enriched environment (DIR) and mice living in a similar enriched cage containing an uninhabited inner cage (ENR) showed enhanced neurogenesis compared to mice in control conditions (CTR). Similarly, the beneficial effects of environmental enrichment on learning performance in the Morris Water maze depended on the direct interaction of the individual with the enrichment. In contrast, indirectly experiencing a stimulus-rich environment failed to improve memory functions indicating that direct interaction and activity within the stimulus-rich environment are necessary to induce structural and functional changes in the hippocampus

Les impacts des écrans tactiles sur les visiteurs dans les musées

L’étude présentée ici met en évidence les nouvelles possibilités et appréhensions qu’ont les visiteurs lorsqu’ils pénètrent dans un espace muséal qui propose, au sein de ses expositions, des interfaces tactiles fixes : elle pointe les implications de ce phénomène qui se généralise dans les institutions muséales

The use of the practice walk test in pulmonary rehabilitation program: National COPD Audit Pulmonary Rehabilitation Workstream

Our aim was to evaluate the use and impact of the practice walk test on enrolment, completion, and clinical functional response to pulmonary rehabilitation (PR) using the 2015 UK National Chronic Obstructive Pulmonary Disease (COPD) Pulmonary Rehabilitation audit data. Patients were assessed according to whether a baseline practice walk test was performed or not. Study outcomes included use of the practice walk test, baseline and change in incremental shuttle walk test distance (ISWD) or 6-minute walk test distance (6MWD), and enrolment to and completion of PR program. Of 7,355 patients, only 1,666 (22.6%) had a baseline practice test. At baseline, the practice walk test group walked further as compared to the no practice walk test group: ISWD, 17.9 m [95% confidence interval (CI) 8.2–27.5 m] and 6MWD, 34.8 m (95% CI 24.7–44.9 m). The practice walk test group were 2.2 times (95% CI 1.8–2.6) more likely to enroll and 17% (95% CI 1.03–1.34) more likely to complete PR. Although the change in ISWD and 6MWD with PR was lower in the practice walk test group, they walked further at discharge assessment. Only 22.6% of the patients in the 2015 National PR audit had a practice walk test at assessment. Those who did had better enrolment, completion, and better baseline walking distance, from which the prescription is set

Whole-body & muscle responses to aerobic exercise training and withdrawal in ageing & COPD

BACKGROUND: Chronic obstructive pulmonary disease (COPD) patients exhibit lower peak oxygen uptake (V′(O(2))(peak)), altered muscle metabolism and impaired exercise tolerance compared with age-matched controls. Whether these traits reflect muscle-level deconditioning (impacted by ventilatory constraints) and/or dysfunction in mitochondrial ATP production capacity is debated. By studying aerobic exercise training (AET) at a matched relative intensity and subsequent exercise withdrawal period we aimed to elucidate the whole-body and muscle mitochondrial responsiveness of healthy young (HY), healthy older (HO) and COPD volunteers to whole-body exercise. METHODS: HY (n=10), HO (n=10) and COPD (n=20) volunteers were studied before and after 8 weeks of AET (65% V′(O(2))(peak)) and after 4 weeks of exercise withdrawal. V′(O(2))(peak), muscle maximal mitochondrial ATP production rate (MAPR), mitochondrial content, mitochondrial DNA (mtDNA) copy number and abundance of 59 targeted fuel metabolism mRNAs were determined at all time-points. RESULTS: Muscle MAPR (normalised for mitochondrial content) was not different for any substrate combination in HO, HY and COPD at baseline, but mtDNA copy number relative to a nuclear-encoded housekeeping gene (mean±sd) was greater in HY (804±67) than in HO (631±69; p=0.041). AET increased V′(O(2))(peak) in HO (17%; p=0.002) and HY (21%; p<0.001), but not COPD (p=0.603). Muscle MAPR for palmitate increased with training in HO (57%; p=0.041) and HY (56%; p=0.003), and decreased with exercise withdrawal in HO (−45%; p=0.036) and HY (−30%; p=0.016), but was unchanged in COPD (p=0.594). mtDNA copy number increased with AET in HY (66%; p=0.001), but not HO (p=0.081) or COPD (p=0.132). The observed changes in muscle mRNA abundance were similar in all groups after AET and exercise withdrawal. CONCLUSIONS: Intrinsic mitochondrial function was not impaired by ageing or COPD in the untrained state. Whole-body and muscle mitochondrial responses to AET were robust in HY, evident in HO, but deficient in COPD. All groups showed robust muscle mRNA responses. Higher relative exercise intensities during whole-body training may be needed to maximise whole-body and muscle mitochondrial adaptation in COPD

Relationship of CT densitometry to lung physiological parameters and health status in alpha-1 antitrypsin deficiency: initial report of a centralised database of the NIHR rare diseases translational research collaborative.

Funder: Foundation for the National Institutes of Health; FundRef: http://dx.doi.org/10.13039/100000009OBJECTIVES: To establish a database network for the study of alpha-1 antitrypsin deficiency (AATD) and compare the results to CT lung density as the most direct measure of emphysema. DESIGN: A central electronic database was established to permit the upload of anonymised patient data from remote sites. Prospectively collected CT data were recorded onto disc, anonymised, analysed at the coordinating centre and compared with the clinical features of the disease. SETTING: Tertiary referral centres with expertise in the management of AATD focused on academic Biomedical Research Units and Wellcome Clinical Research Facilities. PARTICIPANTS: Data were collected from 187 patients over 1 year from eight UK academic sites. This included patient demographics, postbronchodilator physiology, health status and CT. Analysis was undertaken at the coordinating centre in Birmingham. RESULTS: Patient recruitment in the 12 months reached 94% of target (set at 200) covering the whole spectrum of the disease from those with normal lung function to very severe chronic obstructive lung disease. CT scan suitable for analysis was available from 147 (79%) of the patients. CT density, analysed as the threshold for the lowest 15% of lung voxels, showed statistically significant relationships with the objective physiological parameters of lung function as determined by spirometric Global Initiative for Chronic Obstructive Lung Disease (GOLD) severity staging (p<0.001) and carbon monoxide gas transfer (p<0.01). Density also correlated with subjective measures of quality of life (p=0.02). CONCLUSIONS: Establishment of the network for data collection and its transfer was highly successful facilitating future collaboration for the study of this rare disease and its management. CT densitometry correlated well with the objective clinical features of the disease supporting its role as the specific marker of the associated emphysema and its severity. Correlations with subjective measures of health, however, were generally weak indicating other factors play a role

Comparative Effects of R- and S-equol and Implication of Transactivation Functions (AF-1 and AF-2) in Estrogen Receptor-Induced Transcriptional Activity

Equol, one of the main metabolites of daidzein, is a chiral compound with pleiotropic effects on cellular signaling. This property may induce activation/inhibition of the estrogen receptors (ER) a or b, and therefore, explain the beneficial/deleterious effects of equol on estrogen-dependent diseases. With its asymmetric centre at position C-3, equol can exist in two enantiomeric forms (R- and S-equol). To elucidate the yet unclear mechanisms of ER activation/inhibition by equol, we performed a comprehensive analysis of ERa and ERb transactivation by racemic equol, as well as by enantiomerically pure forms. Racemic equol was prepared by catalytic hydrogenation from daidzein and separated into enantiomers by chiral HPLC. The configuration assignment was performed by optical rotatory power measurements. The ER-induced transactivation by R- and S-equol (0.1–10 µM) and 17b-estradiol (E2, 10 nM) was studied using transient transfections of ERα and ERβ in CHO, HepG2 and HeLa cell lines. R- and S-equol induce ER transactivation in an opposite fashion according to the cellular context. R-equol and S-equol are more potent in inducing ERα in an AF-2 and AF-1 permissive cell line, respectively. Involvement of ERα transactivation functions (AF-1 and AF-2) in these effects has been examined. Both AF-1 and AF-2 are involved in racemic equol, R-equol and S-equol induced ERα transcriptional activity. These results could be of interest to find a specific ligand modulating ER transactivation and could contribute to explaining the diversity of equol actions in vivo