88 research outputs found

    The journeys of Wally and Wilma: how scientists reconstruct the movements of fish

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    Have you ever lost your phone and used its GPS function to locate it? To learn about fish, scientists are interested in where fish go and what they experience but GPS technology does not work underwater. Scientists therefore developed small electronic data loggers that can be attached to fish, to record conditions in a fish’s environment. When the fish is recaptured, this information can be downloaded and returned to the scientists. The fish’s movements can then be reconstructed by comparing the recorded measurements with the conditions in the sea. In this article, we explain how this method works and tell you the story of two cod with very dierent fates: Wally, who moved around to feed and to produce ospring, and Wilma, who went on an adventure with a surprising endi

    W 2.1.3 Bedarfserhebung mit Literaturrecherche und explorativen Interviews zur Konzeption und Durchführung modularer FDM-Zertifikatskurse für FDM-Verantwortliche, Forschende und Studierende

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    Um ein institutionalisiertes und nachhaltiges Forschungsdatenmanagement (FDM) in Brandenburg zu erreichen, ist es unabdingbar, strukturierte Schulungsangebote für Forschende und Studierende sowie Schulungs- und Weiterbildungsangebote für FDM-Verantwortliche an jeder Hochschule aufzubauen. Deshalb werden im Rahmen des Verbundprojekts „Institutionalisiertes und nachhaltiges Forschungsdatenmanagement in Brandenburg“ (IN-FDM-BB) modulare FDM-Zertifikatskurse für FDM-Verantwortliche, Forschende und Studierende aller acht am Projekt beteiligten staatlichen, forschenden Hochschulen konzipiert, die sowohl den Hochschulangehörigen sowie den Angehörigen der außeruniversitären Forschungseinrichtungen Brandenburgs offenstehen. Ein Zertifikatskurs „Forschungsdatenmanagement für Studierende“ wurde innerhalb des Projekts bereits konzipiert und durchgeführt. Um ein passgenaues Schulungsangebot für alle drei Zielgruppen entwickeln zu können, wurden auf Basis (1) einer Literaturrecherche zur Vermittlung von FDM-Kompetenzen im Hochschulkontext, (2) eines explorativen Gruppeninterviews im Rahmen eines gemeinsamen Online-Workshops inkl. Gruppendiskussionen mit FDM-Verantwortlichen der acht brandenburgischen Hochschulen, (3) einer Bedarfserhebung unter den Forschenden der Hochschulen und (4), ergänzend, durch Auswertung der Kursevaluationen des oben genannten Zertifikatskurses für Studierende entsprechende Bedarfe, Wünsche und Erfahrungen ermittelt. Diese fließen in die Konzipierung der Kurse ein, beziehungsweise ergänzen das bereits bestehende Konzept eines Zertifikatskurses für Studierende. Nach der Zusammenfassung und dem Ausblick folgt noch ein kurzer Exkurs zu dem projektspezifischen Wissensspeicher für FDM-Materialien.Finanziert durch das Bundesministerium für Bildung und Forschung (BMBF) und die Europäische Union (NextGenerationEU), sowie das Ministerium für Wissenschaft, Forschung und Kultur (MWFK) des Landes Brandenburg

    Stock connectivity patterns and indications of sub-stock component structuring of cod in the Sound in the western Baltic Sea

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    Sustainable management of fish stocks requires knowledge of stock structure and connectivity between spawning and feeding habitats. Cod in the Sound in the western Baltic Sea are an example of a stock component with complex connectivity patterns. Currently cod in this area are managed as part of the western Baltic cod stock, while several studies suggest potential connectivity with the neighbouring stock in Kattegat. Here we assess the degree of ecological connectivity of cod in the Sound with the neighbouring areas using historical tagging data from 1957 to 1987, and contemporary growth data from trawl surveys collected between 2007 and 2021. Furthermore, data from cod tagged outside of the Sound between 1960 and 2018 and recaptured in the Sound was used to examine immigration from outside areas. The ecological connectivity between the Sound and Kattegat appeared to be considerable, primarily during the spawning season. Furthermore, cod tagged in the northern Sound were most likely to be recaptured in Kattegat while cod tagged in the southern part of the Sound were mainly recaptured in the Sound. Only 40 out of 16,789 tagged cod released outside of the Sound were eventually recaptured inside the Sound. Overall, these results highlight the need for further examination into the current stock structure of cod in the western Baltic and adjacent areas

    Authorship, citations, acknowledgments and visibility in social media : symbolic capital in the multifaceted reward system of science

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    The reward system of science is undergoing significant changes, as traditional indicators compete with initiatives that offer novel means of disseminating and assessing scholarly impact. This paper considers a number of aspects of this reward system, including authorship, citations, acknowledgements, and the growing use of social media platforms by academics, with an eye towards identifying contemporary issues relating to scholarly communication practices, as understood through the perspectives of Bourdieu’s symbolic capital and Merton’s recognition paradigms. This paper posits that, while scientific capital remains the foundation upon which the reward system of science is built, this system is revealing itself to be more and more multifaceted, extremely complex, and facing increasing tension between its traditional means of evaluation and the potential of new indicators in the digital era. The paper presents an extended literature review, as well as recommendations for further considerations and empirical research. A better understanding of the perceptions of academics would be necessary to properly assess the effects of these new indicators on scholarly communication practices and the reward system of science

    Propionic Acid Rescues High-Fat Diet Enhanced Immunopathology in Autoimmunity via Effects on Th17 Responses

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    High-fat diets (HFD) are linked to obesity and associated comorbidities and induce pathogenic T helper (Th) 17 cells while decreasing regulatory T cells (Treg). This pro-inflammatory environment also aggravates immunopathology in experimental autoimmune encephalomyelitis (EAE) as a prototype model of T cell mediated autoimmunity. The strong association of HFD to obesity as well as the increasing risk of autoimmunity in the Western world stresses the importance to identify compounds that counteract this metabolically induced pro-inflammatory state in humans. One prominent candidate is the short-chain fatty acid propionate (PA) that was recently identified as potent therapy in the autoimmune disease multiple sclerosis by enhancing Treg cell frequencies and functionality. Mice were fed a HFD rich lauric acid (LA) and treated either with water or PA during MOG35-55-EAE. We analyzed Treg and Th17 cell frequencies in different tissues, antigen-specific cell proliferation and cytokine secretion, investigated Treg cell functionality by suppression assays and IL-10 signaling blockade and employed Western blotting to investigate the involvement of p38-MAPK signaling. Finally, we performed an explorative study in obese and non-obese MS patients, investigating fecal PA concentrations as well as peripheral Th17 and Treg frequencies before and after 90 days of daily PA intake. As compared to controls, mice on a HFD displayed a more severe course of EAE with enhanced demyelination and immune cell infiltration in the spinal cord. PA treatment prevented this disease enhancing effect of HFD by inhibiting Th17 mediated inflammatory processes in the gut and the spleen. Blocking experiments and signaling studies revealed p38-MAPK and IL-10 signaling as important targets linking the beneficial effects of PA treatment and reduced inflammation due to enhanced Treg frequency and functionality. An explorative study in a small group of MS patients revealed reduced PA concentrations in fecal samples of obese MS patients compared to the non-obese group, coinciding with increased Th17 but decreased Treg cells in obese patients. Importantly, PA intake could restore the Treg-Th17 homeostasis. Our data thus identify Th17 responses as an important target for the beneficial effects of PA in HFD and obesity in addition to the recently identified potential of PA as a Treg inducing therapy in T cell mediated autoimmunity

    Association of a Bovine Prion Gene Haplotype with Atypical BSE

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    Background: Atypical bovine spongiform encephalopathies (BSEs) are recently recognized prion diseases of cattle. Atypical BSEs are rare; approximately 30 cases have been identified worldwide. We tested prion gene (PRNP) haplotypes for an association with atypical BSE. Methodology/Principle Findings: Haplotype tagging polymorphisms that characterize PRNP haplotypes from the promoter region through the three prime untranslated region of exon 3 (25.2 kb) were used to determine PRNP haplotypes of six available atypical BSE cases from Canada, France and the United States. One or two copies of a distinct PRNP haplotype were identified in five of the six cases (p = 1.36×10-4, two-tailed Fisher’s exact test; CI95% 0.263–0.901, difference between proportions). The haplotype spans a portion of PRNP that includes part of intron 2, the entire coding region of exon 3 and part of the three prime untranslated region of exon 3 (13 kb). Conclusions/Significance: This result suggests that a genetic determinant in or near PRNP may influence susceptibility of cattle to atypical BSE

    Workshop on accounting for fishers and other stakeholders’ perceptions of the dynamics of fish stocks in ICES advice (WKAFPA)

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    The objective of the Workshop on accounting for fishers and other stakeholders’ perceptions of the dynamics of fish stocks in ICES advice (WKAFPA) was to identify where and how stake- holder information could be incorporated in the ICES fisheries advice process. It adopted an operational definition of the concept of perception, where perceptions result from observations, interpreted in light of experience, that can be supported by data, information and knowledge to generate evidence about them. Stakeholder information can be either structured (e.g. routinely collected information in a standardized format) or unstructured (e.g. experiential information) and either of those can inform decisions made during the production of ICES advice. Most notably, the group identified there was a need to engage with stakeholders earlier in the process, i.e. before benchmarks meetings take place and before preliminary assessment results are used as the basis to predict total allowable catches for upcoming advice (Figure 4.2). It was therefore recommended to include in the ICES process the organisation of pre-bench- mark/roadmap workshops where science and data needs of upcoming benchmarks can be iden- tified, followed by making arrangements how scientists and stakeholders can collaborate to ac- cess, prepare for use (where relevant) and document the structured and unstructured infor- mation well ahead of the benchmark meetings. It was also recommended to organise ‘sense-checking’ sessions with stakeholders when prelim- inary assessments are available but not yet used as the basis for advisory production. This would allow stakeholders and assessment scientists to verify available knowledge and data against stock perceptions and provide additional considerations relevant for the production of TAC ad- vice. Next to these two additional activities, it is recommended that communication on differ- ences in stakeholder perception or data derived perceptions are communicated within the ICES assessment reports as well as in the ICES advice in a transparent manner. Not only should dif- ferences or similarities be documented and communicated, in those cases where there are differ- ences in perception between ICES stock assessments and stakeholders, a working group, external to the assessment working groups, should evaluate these differences and describe whether these differences can be logically explained or require further investigation. This outcome of this pro- cess may potentially lead to new data collection or additional analyses suitable for input to benchmarks. Essential in this entire process is making sure the same language is spoken between scientists and stakeholders, that there are clear and transparent processes in place on how to deal with stakeholder information and communicate clearly how this information is used in the prepara- tion of ICES advice.info:eu-repo/semantics/publishedVersio

    Wirkungen des SGB II auf Personen mit Migrationshintergrund: Projekt IIa1 - 04/06 ; Jahresbericht zum 31.12.2008 - Hauptband

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    Auf Grundlage von Geschäftsdaten, von repräsentativen telefonischen Befragungen und von qualitativen Interviews mit Betroffenen und Fallmanagern wurden die Wirkungen der "Grundsicherung für Arbeitsuchende" auf Migrant/innen untersucht. Ihr Anteil an allen ALG-II Beziehenden beträgt im bundesweiten Durchschnitt 28 Prozent. Im Vergleich zu denjenigen ohne Migrationshintergrund sind sie im Durchschnitt jünger und haben häufiger keinen, aber auch häufiger höhere (Aus-)Bildungsabschlüsse. Die häufig fehlende Anerkennung ausländischer Abschlüsse wirkt sich auf die Arbeitsmarktchancen ebenso negativ aus wie das Fehlen jeglicher Ausbildung. Migrant/innen erhalten bei den Grundsicherungsstellen im Vergleich zu Deutschen ohne Migrationshintergrund mehr Beratungsgespräche, schließen jedoch seltener Eingliederungsvereinbarungen ab und nehmen seltener an Maßnahmen teil. Einige Herkunftsgruppen werden deutlich häufiger mit Sanktionen belegt, andere Herkunftsgruppen deutlich seltener
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