Marketing digital y calidad de servicio electrónico, comprensores industriales S.A.C. distrito de San Martin de Porres 2021

La intención de este estudio fue mostrar si el marketing digital influye para el mejoramiento de la calidad de los servicios electrónicos que brinda Compresores Industriales S.A.C. Distrito San Martín de Porres – 2021. Se aplican metodologías de encuesta, con niveles explicativos, no diseño de experimentos, y un enfoque mixto con una muestra no estocástica de 32 empleados. El método de encuesta utilizado para ello dos cuestionarios con algunas interrogantes que fueron respondidas por la muestra. Los hallazgos identifican los efectos, como se vinculan entre el marketing digital y la calidad de los servicios electrónicos que brinda Compresores Industriales S.A.C. Distrito de San Martín – En 2021, fue, detectado por la prueba rho no paramétrica de Spearman y resultó ser muy significativo (p = .002 <a = .01); por lo tanto, 99% Con confianza, puede ver que el marketing digital tiene un efecto directo y (más) en la calidad de los servicios electrónicos. Esto también conduce a un nivel medio de correlación entre variables (R =, 550 **)

Mapping Regions of Provenance for Italy

In the follow-up of 1999/105/CE Directive on national level, the new map of regions of provenance for forest reproductive materials of Italy is adopted as reference for the national register of forest basic materials. The new map was outlined to match needs linked to the transposition of European legislation to the complexity of the Peninsula’s environment and the national nursery system. The main objective in this technical note is to present the map units in relation to the distribution of main forest species. The map units of ecoregional meaning might facilitate new allocations for forest reproductive materials which are needed to increase genetic diversity. Furthermore, studies on genetic variability of forest species are required to understand the possible interactions between the ecological amplitude of forest species, their actual genetic diversity, and possible adaptation to future climate conditions

COL R Acinetobacter baumannii sRNA Signatures : Computational Comparative Identification and Biological Targets

Multidrug-Resistant (MDR) and Extensively Drug Resistant (XDR) Acinetobacter baumannii (Ab) represent a serious cause of healthcare-associated infections worldwide. Currently, the available treatment options are very restricted and colistin-based therapies are last-line treatments of these infections, even though colistin resistant (COL R) Ab have rarely been isolated yet. In bacteria, small non-coding RNAs (sRNAs) have been implicated in regulatory pathways of different biological functions, however, no knowledge exists about the sRNA role on the biological adaptation in COL R Ab. Our study investigated two Italian XDR isogenic colistin-susceptible/resistant (COL S/R) Ab strain-pairs to discover new sRNA signatures. Comparative sRNA transcriptome (sRNAome) analyses were carried out by Illumina RNA-seq using both a Tru-Seq and a Short Insert library, whilst Ab ATCC 17978 and ACICU Reference Genome assembly, mapping, annotation and statistically significant differential expression (q -value ≤ 0.01) of the raw reads were performed by the Rockhopper tool. A computational filtering, sorting only similarly statistically significant differentially expressed (DE) sRNAs mapping on the same gene in both COL R Ab isolates was conducted. COL R vs. COL S sRNAome, analyzed integrating the DE sRNAs obtained from the two different libraries, revealed some statistically significant DE sRNAs in COL R Ab. In detail, we found: (i) two different under-expressed cis -acting sRNAs (Ab sRNA and Ab sRNA) mapping in antisense orientation the 16S rRNA gene A1S_r01, (ii) one under-expressed cis -acting sRNA (Ab sRNA) targeting the A1S_2505 gene (hypothetical protein), (iii) one under-expressed microRNA-size small RNA fragment (Ab sRNA) and its pre-micro Ab sRNA targeting the A1S_0501 gene (hypothetical protein), (iv) as well as an over-expressed microRNA-size small RNA fragment (Ab sRNA) and its pre-micro Ab sRNA targeting the A1S_3097 gene (signal peptide). Custom TaqMan ® probe-based real-time qPCRs validated the expression pattern of the selected sRNA candidates shown by RNA-seq. Furthermore, analysis on sRNA ΔA1S_r01, ΔA1S_2505 as well as the over-expressed A1S_3097 mutants revealed no effects on colistin resistance. Our study, for the first time, found the sRNAome signatures of clinical COL R Ab with a computational prediction of their targets related to protein synthesis, host-microbe interaction and other different biological functions, including biofilm production, cell-cycle control, virulence, and antibiotic-resistance

HIV and SARS-CoV-2 Co-Infection: From Population Study Evidence to In Vitro Studies

Human immunodeficiency virus type 1 (HIV-1) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have caused two major viral outbreaks during the last century. Two major aspects of HIV-1 and SARS-CoV-2 co-infection have been extensively investigated and deserve attention. First, the impact of the co-infection on the progression of disease caused by HIV-1 or SARS-CoV-2. Second, the impact of the HIV-1 anti-retroviral treatment on SARS-CoV-2 infection. In this review, we aim to summarize and discuss the works produced since the beginning of the SARS-CoV-2 pandemic ranging from clinical studies to in vitro experiments in the context of co-infection and drug development

Secondary-electron emission induced by in vacuo surface excitations near a polycrystalline Al surface

The double-differential spectrum of coincidences between backscattered electrons and secondary electrons (SEs) emitted from a polycrystalline Al surface bombarded with 100-eV electrons was measured. For energy losses of the scattered electron in between the work function of Al and the bulk plasmon energy, a sharp peak is observed in the SE spectra, corresponding to ejection of a single electron near the Fermi edge receiving the full energy loss and momentum of the primary electron. This process predominantly takes place when the primary electron suffers a surface energy loss in vacuum, and leads to SE ejection from the very surface. At energy losses just above the bulk plasmon energy, a sharp transition is observed, corresponding to a sudden increase in the depth of ejection. The latter is a direct consequence of the complementarity of surface and bulk plasmons, the so-called Begrenzungs effect