Liver transplantation for type IV glycogen storage disease

TYPE IV glycogen storage disease is a rare autosomal recessive disorder (also called Andersen's disease1 or amylopectinosis) in which the activity of branching enzyme alpha-1, 4-glucan: alpha-1, 4-glucan 6-glucosyltransferase is deficient in the liver as well as in cultured skin fibroblasts and other tissues.2,3 This branching enzyme is responsible for creating branch points in the normal glycogen molecule. In the relative or absolute absence of this enzyme, an insoluble and irritating form of glycogen, an amylopectin-like polysaccharide that resembles plant starch, accumulates in the cells. The amylopectin-like form is less soluble than normal glycogen, with longer outer and inner chains. © 1991, Massachusetts Medical Society. All rights reserved

Warrant for $496.89 due John A. Watie, signed by Cherokee leader Stand Watie. January 26, 1847.

Stand Watie signs a warrant for $496.89 owed his brother John A. Watie, January 26, 1847.https://digitalcommons.wofford.edu/littlejohnmss/1267/thumbnail.jp

Mechanisms of exercise-induced improvements in the contractile apparatus of the mammalian myocardium

One of the main outcomes of aerobic endurance exercise training is the improved maximal oxygen uptake, and this is pivotal to the improved work capacity that follows the exercise training. Improved maximal oxygen uptake in turn is at least partly achieved because exercise training increases the ability of the myocardium to produce a greater cardiac output. In healthy subjects, this has been demonstrated repeatedly over many decades. It has recently emerged that this scenario may also be true under conditions of an initial myocardial dysfunction. For instance, myocardial improvements may still be observed after exercise training in post-myocardial infarction heart failure. In both health and disease, it is the changes that occur in the individual cardiomyocytes with respect to their ability to contract that by and large drive the exercise training-induced adaptation to the heart. Here, we review the evidence and the mechanisms by which exercise training induces beneficial changes in the mammalian myocardium, as obtained by means of experimental and clinical studies, and argue that these changes ultimately alter the function of the whole heart and contribute to the changes in whole-body function

Refractive Index of Humid Air in the Infrared: Model Fits

The theory of summation of electromagnetic line transitions is used to tabulate the Taylor expansion of the refractive index of humid air over the basic independent parameters (temperature, pressure, humidity, wavelength) in five separate infrared regions from the H to the Q band at a fixed percentage of Carbon Dioxide. These are least-squares fits to raw, highly resolved spectra for a set of temperatures from 10 to 25 C, a set of pressures from 500 to 1023 hPa, and a set of relative humidities from 5 to 60%. These choices reflect the prospective application to characterize ambient air at mountain altitudes of astronomical telescopes.Comment: Corrected exponents of c0ref, c1ref and c1p in Table

A Geographical Investigation of Football and its Fans at Auburn University

In Auburn, AL, football, and especially college football, reigns supreme. Particularly, interest is placed on the Tigers, the team representing the local institution, Auburn University. This research paper investigates the spatio-temporal role of football at Auburn University and presents findings that are indicative of the spatial characteristics of Auburn’s football fan region and their relationship with the team. Sources used to map Auburn’s fan region included records of 2010 season ticket holders and Auburn booster club locations and membership figures. The fans are predominantly found in Alabama and Georgia. Heavy concentrations are seen in Auburn, as well as major urban centers with close proximity to Auburn such as Atlanta, Birmingham, and Montgomery. Questionnaire surveys of Auburn fans found that the majority of participants had attended Auburn and/or had family members who had attended Auburn. Fans commonly mentioned words like family, tradition, and atmosphere when describing why they liked Auburn Tigers football

Discovery and Development of Potassium-Based Metal Halide Scintillators for Radiation Detection Applications

Scintillators are important materials for radiation detection applications such as homeland security, geological exploration, and medical imaging. Scintillators for nuclear nonproliferation applications must have excellent energy resolution to distinguish the gamma-ray signatures of potentially dangerous radioactive sources from non-threat radioactive sources. There is an established need for scintillators with energy resolution in the 1-2 % (percent) range at 662 kiloelectron volts. However, there are challenges surrounding the development of this new generation of high light yield/high resolution scintillators; for example, the high cost of production due to low crystal yield and slow growth process, and crystal inhomogeneity. In this work we present the crystal growth, the physical and scintillation properties of four newly discovered europium doped scintillators; potassium strontium iodide (KSr2I5:Eu), potassium strontium bromide (KSr2Br5:Eu), potassium barium iodide (KBa2I5:Eu), potassium barium iodide (K2BaI4:Eu). These scintillators materials had excellent properties with light yields well above 50,000 photons per megaelectron volt and energy resolution between 2.4 – 2.9% (Percent) at 662 kiloelectron volts.Due to its ease of growth, Europium doped potassium strontium iodide was selected for further development. We focused our efforts optimizing the growth parameters required to grow one-inch diameter crystals at pulling rates up to 7 millimeters per hour. High performing, nearly crack free single crystals measuring up to one-inch diameter by six-inch in length were grown via the vertical Bridgman technique. The scintillation properties were evaluated using specimen that ranged ranging from 0.012 to 54 cubic centimeters.To further enhance the light yield and energy resolution in europium doped potassium strontium iodide, anion and cation substitution were investigated. We found that replacing 2% (percent) of the matrix iodine atoms with bromine increased the light yield from 84,000 to 97,900 ph/MeV (Photon per megaelectron volt), while maintaining it excellent energy resolution of 3.0% (percent) at 662 keV (Kiloelectron volts). We also found that by replacing 35% of strontium for barium not only increased the light yield increased from 84,000 to 120,000 ph/MeV (Photon per megaelectron volt) and but also improved the energy resolution from 3.0 to 2.3% (percent) at 662 keV (Kiloelectron volts) for 1 cm3 (cubic centimeter) crystals

Analysis of Potential and Efficiency of Electric Generation Using Thermoelectric Effect

This research identifies the electrical potential associated with Thermoelectric Generators (TEG) under the incidence of solar rays and performs efficiency comparison using this type of devices and those photovoltaic. TEG characterization and modeling is presented to favor the estimation of the electrical potential, defined as power density (W/m2). The proper operation of thermal harvesting lays in maintaining a temperature difference of at least 26.31K between the TEG sides. With this requirement fulfilled, power conversion eficiencies of about 26.43% are obtained, higher than that of high-quality solar panels and without efficiency reductions associated with heating and soiling, while keeping the same superficial area of only 16cm 2. An estimate of at least 407.3mW corresponding to 2.44Wh of available energy is found considering specific operation hours determined statistically for a given geographic location. Thus, given such performance metric, a complete power unit is devised complementing the thermoelectric energy harvesting with a Li-Po battery to guarantee in that way a continuous operation. The total energy available from the prototype allows maintaining a battery discharge percentage of 38.05% considering the energy budget of a low-power remote sensor.MaestríaMagister en Ingeniería Electrónic

The Generic Properties of Equilibrium Correction Mechanisms

Linear dynamic equilibrium correction mechanisms are shown to follow from the discretisation of continuous economic processes with steady-state solutions. In addition, the proposed procedure on the coefficients of the dynamic econometric model