612 research outputs found

    Ptarmigan Fiord basement-cover thrust imbricates, Baffin Island, Nunavut

    Get PDF
    The rocks at Ptarmigan Fiord on the Hall Peninsula of Baffin Island underwent midcrustal deformation during the formation of the Paleoproterozoic Trans-Hudson Orogen. The structural style in the region is dominated by imbricate panels of Archean basement orthogneiss and Paleoproterozoic supracrustal strata, interpreted to have been deformed by thick- skinned ductile thrusting. Basement rocks comprise amphibolite-facies metatonalite, metagranodiorite, metaquartz-diorite and metamonzogranite, and cover rocks comprise amphibolite-facies migmatitic pelitic and semipelitic schist, psammitic schist, amphibolite, calcsilicate and quartzite. The S 1a penetrative foliation is variably present in basement rocks and consis- tently present in cover rocks, and is defined by alignment of biotite, sillimanite and leucogranite that formed before and dur- ing the thermal metamorphic peak. The S 1a foliation was deformed by F 1b isoclinal folds with an amplitude of 100 m. These structures are interpreted as forming during a D 1 east-west crustal shortening event. Basement and cover imbrication oc- curred after the thermal metamorphic peak and is interpreted as D 2 thick-skinned ductile thrusting. Ductile thrust faults at the base of seven basement-cover slices are identified on the basis of repetition of units and strain localization, and are inter- preted as predominantly south-to-southeast verging on the basis of shear-sense indicators. There are two structural panels of D 2 thrust imbricates, one in the northwestern part of the map area and one in the eastern part of the map area. Map-scale crosscutting relationships indicate that the northwestern panel overthrusted the eastern panel on a southeasterly T 2c -di- rected thrust fault, following a F 2b folding event that folded the T 2a basement-cover thrust imbricates in the eastern panel. The Ptarmigan Fiord area contains a world-class exposure of thick-skinned structures as they are spectacularly delineated by belts of distinctive grey-weathering Archean basement rocks and brown- to black-weathering Paleoproterozoic supra- crustal rocks

    Personal preferences for Personalised Trials among patients with chronic diseases: an empirical Bayesian analysis of a conjoint survey.

    Get PDF
    OBJECTIVE: To describe individual patient preferences for Personalised Trials and to identify factors and conditions associated with patient preferences. DESIGN: Each participant was presented with 18 conjoint questions via an online survey. Each question provided two choices of Personalised Trials that were defined by up to eight attributes, including treatment types, clinician involvement, study logistics and trial burden on a patient. SETTING: Online survey of adults with at least two common chronic conditions in the USA. PARTICIPANTS: A nationally representative sample of 501 individuals were recruited from the Chronic Illness Panel by Harris Poll Online. Participants were recruited from several sources, including emails, social media and telephone recruitment of the target population. MAIN OUTCOME MEASURES: The choice of Personalised Trial design that the participant preferred with each conjoint question. RESULTS: There was large variability in participants\u27 preferences for the design of Personalised Trials. On average, they preferred certain attributes, such as a short time commitment and no cost. Notably, a population-level analysis correctly predicted 62% of the conjoint responses. An empirical Bayesian analysis of the conjoint data, which supported the estimation of individual-level preferences, improved the accuracy to 86%. Based on estimates of individual-level preferences, patients with chronic pain preferred a long study duration (p≤0.001). Asthma patients were less averse to participation burden in terms of data-collection frequency than patients with other conditions (p=0.002). Patients with hypertension were more cost-sensitive (p\u3c0.001). CONCLUSION: These analyses provide a framework for elucidating individual-level preferences when implementing novel patient-centred interventions. The data showed that patient preference in Personalised Trials is highly variable, suggesting that individual differences must be accounted for when marketing Personalised Trials. These results have implications for advancing precise interventions in Personalised Trials by indicating when rigorous scientific principles, such as frequent monitoring, is feasible in a substantial subset of patients

    Comparison of earthquake-triggered turbidites from the Saguenay (Eastern Canada) and Reloncavi (Chilean margin) Fjords: implications for paleoseismicity and sedimentology

    Get PDF
    International audienceHigh-resolution seismic profiles along with physical and sedimentological properties of sediment cores from the Saguenay (Eastern Canada) and Reloncavi (Chile) Fjords allowed the identification of several decimeter to meter-thick turbidites. In both fjords, the turbidites were associated with large magnitude historic and pre-historic earthquakes including the 1663 AD (M > 7) earthquake in the Saguenay Fjord, and the 1960 (M 9.5), 1837 (M ~ 8) and 1575 AD major Chilean subduction earthquakes in the Reloncavi Fjord. In addition, a sand layer with exoscopic characteristics typical of a tsunami deposit was observed immediately above the turbidite associated with the 1575 AD earthquake in the Reloncavi Fjord and supports both the chronology and the large magnitude of that historic earthquake. In the Saguenay Fjord, the earthquake-triggered turbidites are sometimes underlying a hyperpycnite associated with the rapid breaching and draining of a natural dam formed by earthquake-triggered landslides. Similar hyperpycnal floods were also recorded in historical and continental geological archives for the 1960 and 1575 AD Chilean subduction earthquakes, highlighting the risk of such flood events several weeks or months after main earthquake. In both fjords, as well as in other recently recognized earthquake-triggered turbidites, the decimeter-to meter-thick normally-graded turbidites are characterized by a homogeneous, but slightly fining upward tail. Finally, this paper also emphasizes the sensitivity of fjords to record historic and pre-historic seismicity

    Source-sink cooperation dynamics constrain institutional evolution in a group-structured society

    Full text link
    Societies change through time, entailing changes in behaviors and institutions. We ask how social change occurs when behaviors and institutions are interdependent. We model a group-structured society in which the transmission of individual behavior occurs in parallel with the selection of group-level institutions. We consider a cooperative behavior that generates collective benefits for groups but does not spread between individuals on its own. Groups exhibit institutions that increase the diffusion of the behavior within the group, but also incur a group cost. Groups adopt institutions in proportion to their fitness. Finally, cooperative behavior may also spread globally. As expected, we find that cooperation and institutions are mutually reinforcing. But the model also generates behavioral source-sink dynamics when cooperation generated in institutional groups spreads to non-institutional groups, boosting their fitness. Consequently, the global diffusion of cooperation creates a pattern of institutional free-riding that limits the evolution of group-beneficial institutions. Our model suggests that, in a group-structured society, large-scale change in behavior and institutions (i.e. social change) can be best achieved when the two remain correlated, such as through the spread successful pilot programs

    Forschendes Lernen. Konzeptuelle Grundlagen und Potenziale digitaler Medien

    Full text link
    Im folgenden Artikel wird dargelegt, was unter dem Konzept des forschenden Lernens zu verstehen ist und welche Einsatzmöglichkeiten sich für das forschende Lernen im Kontext Universität ergeben. Dabei werden speziell diejenigen Merkmale theoretisch herausgearbeitet, die aus Lehrendenperspektive Anknüpfungspunkte für einen prozessbegleitenden Medieneinsatz bieten. Exemplarisch wird eine Lehrveranstaltung angeführt, die auf Fallebene zeigt, wie ein forschungsorientiertes Seminar um digitale Medien angereichert werden kann und welche Chancen und Grenzen sich bei der selbstgesteuerten Verwendung digitaler Medienangebote ergeben. Die Evaluation des Seminars zeigt, dass die Studierenden einen großen Lernzuwachs erleben, jedoch teilweise durch die Offenheit des Lernens überfordert sind. Diese und andere Gründe führen dazu, dass die von Lehrenden vorgeschlagenen Medienangebote selten bis kaum genutzt werden. Zudem sehen Lernende die Qualität virtuell distribuierter Inhalte kritisch, was sich auf die Akzeptanz und die Nutzung der vorhandenen digitalen Medienangebote auswirkt. (DIPF/Orig.

    Tacky Elastomers to Enable Tear-Resistant and Autonomous Self-Healing Semiconductor Composites

    Get PDF
    Mechanical failure of π-conjugated polymer thin films is unavoidable under cyclic loading conditions, due to intrinsic defects and poor resistance to crack propagation. Here, the first tear-resistant and room-temperature self-healable semiconducting composite is presented, consisting of conjugated polymers and butyl rubber elastomers. This new composite displays both a record-low elastic modulus

    Tacky Elastomers to Enable Tear-Resistant and Autonomous Self-Healing Semiconductor Composites

    Get PDF
    Mechanical failure of π-conjugated polymer thin films is unavoidable under cyclic loading conditions, due to intrinsic defects and poor resistance to crack propagation. Here, the first tear-resistant and room-temperature self-healable semiconducting composite is presented, consisting of conjugated polymers and butyl rubber elastomers. This new composite displays both a record-low elastic modulus
    • …
    corecore