Minimal Seesaw as an Ultraviolet Insensitive Cure for the Problems of Anomaly Mediation

We show that an intermediate scale supersymmetric left-right seesaw scenario with automatic R-parity conservation can cure the problem of tachyonic slepton masses that arises when supersymmetry is broken by anomaly mediation, while preserving ultraviolet insensitivity. The reason for this is the existence of light B - L = 2 higgses with yukawa couplings to the charged leptons. We find these theories to have distinct predictions compared to the usual mSUGRA and gauge mediated models as well as the minimal AMSB models. Such predictions include a condensed gaugino mass spectrum and possibly a correspondingly condensed sfermion spectrum.Comment: 19 pages, 1 figur

Running with Triplets: How Slepton Masses Change With Doubly-Charged Higgses

We examine the slepton masses of SUSYLR models and how they change due the presence of light-doubly charged higgs bosons. We discover that the measurement of the slepton masses could bound and even predict the value of the third generation Yukawa coupling of leptons to the SU(2)_R Triplets. We also consider the unification prospects for this model with the addition of left-handed, B - L = 0 triplets--a model we call the Triplet Extended Supersymmetric Standard Model (TESSM). Finally, we discuss the changes in the slepton masses due to the presence of the SU(2)_L triplets.Comment: 20 pages, 6 figures, 4 table

Gauge Mediated SUSY Breaking via Seesaw

We present a simple scenario for gauge mediated supersymmetry breaking where the messengers are also the fields that generate neutrino masses. We show that the simplest such scenario corresponds to the case where neutrino masses are generated through the Type I and Type III seesaw mechanisms. The entire supersymmetric spectrum and Higgs masses are calculable from only four input parameters. Since the electroweak symmetry is broken through a doubly radiative mechanism, meaning a nearly zero B-term at the messenger scale which runs down to acceptable values, one obtains quite a constrained spectrum for the supersymmetric particles whose properties we describe. We refer to this mechanism as "nu-GMSB".Comment: a few corrections, references adde

Using Intervention Mapping to Develop an Efficacious Multicomponent Systems-Based Intervention to Increase Human Papillomavirus (HPV) Vaccination in a Large Urban Pediatric Clinic Network

Background: The CDC recommends HPV vaccine for all adolescents to prevent cervical, anal, oropharyngeal, vaginal, vulvar, and penile cancers, and genital warts. HPV vaccine rates currently fall short of national vaccination goals. Despite evidence-based strategies with demonstrated efficacy to increase HPV vaccination rates, adoption and implementation of these strategies within clinics is lacking. The Adolescent Vaccination Program (AVP) is a multicomponent systems-based intervention designed to implement five evidence-based strategies within primary care pediatric practices. The AVP has demonstrated efficacy in increasing HPV vaccine initiation and completion among adolescents 10-17 years of age. The purpose of this paper is to describe the application of Intervention Mapping (IM) toward the development, implementation, and formative evaluation of the clinic-based AVP prototype. Methods: Intervention Mapping (IM) guided the development of the Adolescent Vaccination Program (AVP). Deliverables comprised: a logic model of the problem (IM Step 1); matrices of behavior change objectives (IM Step 2); a program planning document comprising scope, sequence, theory-based methods, and practical strategies (IM Step 3); functional AVP component prototypes (IM Step 4); and plans for implementation (IM Step 5) and evaluation (IM Step 6). Results: The AVP consists of six evidence-based strategies implemented in a successful sequenced roll-out that (1) established immunization champions in each clinic, (2) disseminated provider assessment and feedback reports with data-informed vaccination goals, (3) provided continued medical and nursing education (with ethics credit) on HPV, HPV vaccination, message bundling, and responding to parent hesitancy, (4) electronic health record cues to providers on patient eligibility, and (5) patient reminders for HPV vaccine initiation and completion. Conclusions: IM provided a logical and systematic approach to developing and evaluating a multicomponent systems-based intervention to increase HPV vaccination rates among adolescents in pediatric clinics

Spontaneous R-Parity Breaking in SUSY Models

We investigate a mechanism for spontaneous R-parity breaking in a class of extensions of the minimal supersymmetric standard model with an extra Abelian gauge symmetry which is a linear combination of B-L and weak hypercharge. Both U(1)_X and R-parity are broken by the vacuum expectation value of the right-handed sneutrinos which is proportional to the soft SUSY masses. In these models the mechanism for spontaneous R-parity violation can be realized even with positive soft masses. In this context one has a realistic mechanism for generating neutrino masses as well as a realistic spectrum. We briefly discuss the possible collider signals which could be used to test the theory, the contributions for proton decay and the possibility of a gravitino as a dark matter candidate.Comment: 9 pages, typos corrected, to appear in Physical Review

Participatory arts interventions promote interpersonal and intergroup prosocial intentions in middle childhood

We report the results of two experiments which test the potential of arts engagement for promoting prosocial intentions. Experiment 1 (N = 216) tested the impact of a participatory arts intervention (vs. a control condition) on children's empathy and interpersonal prosocial intentions. Experiment 2 (N = 174) tested the impact of a participatory arts intervention (vs. a control condition) on children's prosocial intentions toward outgroup members under competitive and non-competitive conditions. Experiment 1 showed that the participatory arts intervention significantly increased children's interpersonal prosocial intentions, but not their empathy. Experiment 2 showed that, under competitive conditions, the participatory arts intervention significantly increased prosocial intentions toward outgroup members, an effect that persisted for six months beyond the intervention. Under non-competitive conditions, the participatory arts intervention consolidated improvements in prosocial intentions toward outgroup members. Overall, the results confirm the hypothesis that participatory arts engagement can promote prosocial intentions during middle childhood

Yersinia pestis insecticidal-like toxin complex (Tc) family proteins: characterization of expression, subcellular localization, and potential role in infection of the flea vector

BACKGROUND: Toxin complex (Tc) family proteins were first identified as insecticidal toxins in Photorhabdus luminescens and have since been found in a wide range of bacteria. The genome of Yersinia pestis, the causative agent of bubonic plague, contains a locus that encodes the Tc protein homologues YitA, YitB, YitC, and YipA and YipB. Previous microarray data indicate that the Tc genes are highly upregulated by Y. pestis while in the flea vector; however, their role in the infection of fleas and pathogenesis in the mammalian host is unclear. RESULTS: We show that the Tc proteins YitA and YipA are highly produced by Y. pestis while in the flea but not during growth in brain heart infusion (BHI) broth at the same temperature. Over-production of the LysR-type regulator YitR from an exogenous plasmid increased YitA and YipA synthesis in broth culture. The increase in production of YitA and YipA correlated with the yitR copy number and was temperature-dependent. Although highly synthesized in fleas, deletion of the Tc proteins did not alter survival of Y. pestis in the flea or prevent blockage of the proventriculus. Furthermore, YipA was found to undergo post-translational processing and YipA and YitA are localized to the outer membrane of Y. pestis. YitA was also detected by immunofluorescence microscopy on the surface of Y. pestis. Both YitA and YipA are produced maximally at low temperature but persist for several hours after transfer to 37°C. CONCLUSIONS: Y. pestis Tc proteins are highly expressed in the flea but are not essential for Y. pestis to stably infect or produce a transmissible infection in the flea. However, YitA and YipA localize to the outer membrane and YitA is exposed on the surface, indicating that at least YitA is present on the surface when Y. pestis is transmitted into the mammalian host from the flea

Temperature Dependence of the Elastic Constants of Thoria Specimens of Varying Porosity

L:rh~ tempera.t ure d ependence of Young's a nd the shear modu lus of 18 t hori a specimens of p orOSltlCS ra ngm g from 3.7 to 39.4 p ercent ha ve been m easured by t he d yna mic resona nce m ethod. The t emperat ure ran ge of th e m eas urem ents was from 25 to 1,300 °0. Th e moduli d ecreased with in cr ea sing temperature in gen era l accordance wit h the p attern obser ved fo r other polycrystalli ne m ate rials. Th e r elati ve decrease in modulus wi th tem perat ure for all t he m aterials was essen tia lly indep endent of porosity up to a bou t 800 °e. Above t his temperat ure the r elative decr ease in modulus for t h e hi gh porosity specimens tended to be more rapid t han for the low p orosity sp ecimens. Also, P oisso n's ratio for a ny a rt icular specimen r ema ined consta nt over t he ent ire temperature ra nge of m eas uremen t

Brachial plexus lipomatosis with perineurial pseudoonion bulb formation: Result of a mosaic PIK3CA mutation in the para???axial mesoderm state

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When Anomaly Mediation is UV Sensitive

Despite its successes---such as solving the supersymmetric flavor problem---anomaly mediated supersymmetry breaking is untenable because of its prediction of tachyonic sleptons. An appealing solution to this problem was proposed by Pomarol and Rattazzi where a threshold controlled by a light field deflects the anomaly mediated supersymmetry breaking trajectory, thus evading tachyonic sleptons. In this paper we examine an alternate class of deflection models where the non-supersymmetric threshold is accompanied by a heavy, instead of light, singlet. The low energy form of this model is the so-called extended anomaly mediation proposed by Nelson and Weiner, but with potential for a much higher deflection threshold. The existence of this high deflection threshold implies that the space of anomaly mediated supersymmetry breaking deflecting models is larger than previously thought.Comment: 14 pages, 1 figure (version to appear in JHEP