Caddoan Reburial

On February 7, 1993 in eastern Texas, the remains of a prehistoric Caddoan Indian were reburied in the original grave. A small ceremony was held to mark the occasion. Representatives of the Caddo Tribe from Oklahoma and Louisiana were in attendance, as were members of the Nonheast Texas Archeological Society (NETAS). This report deals with one case of recently excavated human remains

Archaeological Investigation at the Marshall Powder Mill (41HS17), Confederate States of America 1863-1865, Harrison County, Texas: 1994 Season

The Northeast Texas Archeological Society, in conjunction with the East Texas, Dallas, and Tarrant County archeological societies, reinstated archaeological investigations at the Marshall Powder Mill (41HS17) in 1994 following several years of delicate negotiations with the landowner about the value of preserving this archaeological site. The Marshall Powder Mill manufactured gunpowder, small arms and cannon, and refurbished weaponry, and was one of several arsenals that served the Trans-Mississippi Department of the Confederate States of America from 1863 to 1865. None have been thoroughly investigated archaeologically, however, thereby ignoring a major aspect of the Confederacy\u27s war effort, and an important industrial enterprise. Building foundations, earthworks, roads, and an artificial channel race remain essentially undisturbed within the Loop 390 corridor and the privately-owned portions of the site; the eastern one-third of the site has been destroyed by a modern lumber mill. Although the site is listed on the National Register of Historic Places, there is no concerted plan for preservation of this Civil War military-industrial complex. Little historical documentation exists as to the number and types of buildings, their locations, or the activities that were conducted at the Marshall Powder Mill. The single map in the National Archives was captured by Federal troops in 1864, and only indicates a few of the buildings and none of the earthworks. Apparently the Confederates were concerned with security, and the commander, Major George D. Alexander, destroyed or removed all records prior to Federal occupation of the site in 1865. Therefore, the archaeological remains speak the clearest about the Marshall Powder Mill\u27s buildings and their functions, and may be the only sure means of reconstructing the layout and design of the arsenal, as well as ancillary fortifications, buildings, and structures around Marshall that date to the Civil War period

Possible Archaeological Sites within the City Limits of Jefferson, Texas

In 1992, the author accompanied a longtime resident of Jefferson on a tour of the city to examine historic and prehistoric sites within the city limits that might be of archaeological interest. He became aware of many of these sites over 20 years ago while growing up in the area. The condition of the sites has, of course, changed radically since that time. Enough information about the sites was revealed to indicate where it might be worthwhile in the future to do more extensive archaeological and historical research. We began our tour at 12:00 noon on July 24, 1992. My host drove, allowing the author to take notes on the sites. The first stops on the tour were in North Jefferson, while later in the day some possible sites in South and East Jefferson were looked at. Each site was numbered chronologically as they were shown to the author; the sites were also plotted on a map of Marion County and Jefferson. The same numerical system will be used in this report

Archaeological Investigations at the Marshall Powdermill and Arsenal (41HS17), Confederate States of America 1864-1865, Harrison County, Texas

The Northeast Texas Archeological Society (NETAS), in conjunction with the East Texas, Dallas, and Tarrant County Archeological Societies has completed a year-long project at the Marshall Powder Mill, 41HS17, Harrison County, Texas. The Marshall Powder Mill manufactured gunpowder, small arms and cannon, and refurbished weaponry. It is one of several arsenals that served the Trans-Mississippi Department of the Confederate States of America, and was among the last in operation from 1864 to 1865. None have been thoroughly investigated archaeologically, thereby ignoring a major aspect of the Confederacy\u27s war effort and an important industrial enterprise

Legionella pneumophila strain 130b evades macrophage cell death independent of the effector SidF in the absence of flagellin

International audienceThe human pathogen Legionella pneumophila must evade host cell death signaling to enable replication in lung macrophages and to cause disease. After bacterial growth, however, L. pneumophila is thought to induce apoptosis during egress from macrophages. The bacterial effector protein, SidF, has been shown to control host cell survival and death by inhibiting pro-apoptotic BNIP3 and BCL-RAMBO signaling. Using live-cell imaging to follow the L. pneumophila-macrophage interaction, we now demonstrate that L. pneumophila evades host cell apoptosis independent of SidF. In the absence of SidF, L. pneumophila was able to replicate, cause loss of mitochondria membrane potential, kill macrophages, and establish infections in lungs of mice. Consistent with this, deletion of BNIP3 and BCL-RAMBO did not affect intracellular L. pneumophila replication, macrophage death rates, and in vivo bacterial virulence. Abrogating mitochondrial cell death by genetic deletion of the effectors of intrinsic apoptosis, BAX, and BAK, or the regulator of mitochondrial permeability transition pore formation, cyclophilin-D, did not affect bacterial growth or the initial killing of macrophages. Loss of BAX and BAK only marginally limited the ability of L. pneumophila to efficiently kill all macrophages over extended periods. L. pneumophila induced killing of macrophages was delayed in the absence of capsase-11 mediated pyroptosis. Together, our data demonstrate that L. pneumophila evades host cell death responses independently of SidF during replication and can induce pyroptosis to kill macrophages in a timely manner

Venous thrombosis in immunocompetent patients with acute cytomegalovirus infection: a complication that may be underestimated

In the present study, we retrospectively studied clinical and laboratory findings associated with cytomegalovirus (CMV) infection in immunocompetent patients. We focused on severe CMV infection. Among 38 patients, five had a severe form of infection: one had meningitis, one had symptomatic thrombocytopenia and three had venous thromboses with pulmonary embolism, a rarely described complication. CMV-induced thrombosis has been reported in immunocompromised patients such as transplant recipients and patients with AIDS. Recent case reports have also described thrombotic phenomena in immunocompetent patients with CMV infection. Our study suggests that venous thrombosis during acute CMV infection is an underestimated complication

Modelling the location and consequences of aircraft accidents

Following the completion of two projects funded by the UK EPSRC and two for the Airports Cooperative Research Program, ACRP (2008, 2011), this paper aims to summarise the work on the location and consequence models . The projects overall focused on the development of an improved airport risk assessment methodology aimed at assessing risks related to aircraft accidents at and in the vicinity of airports and managing Runway Safety Areas (RSAs) as a risk mitigation measure. The improved methodology is more quantitative, risk-sensitive, flexible and transparent than traditional risk assessment approaches. As such, it contributes to the implementation of Safety Management Systems at airports, as stipulated by the International Civil Aviation Organisation. The innovative elements of this research are two-fold. First, an accident database covering undershoots, overruns, and veer-off crashes close to runways at airports has been compiled and data on incidents has been added. Second, accident frequency models have been developed, for example, identifying the contribution of influencing factors such as variations in meteorological conditions. To allow airport risk to then be calculated entails comparing these cases with those contained in a ‘normal operations database’ where no accidents have been recorded but where the influencing factors are also known. Subsequent models have examined the location of the accidents and their consequences. It is this work that is the focus of this paper. Future work will focus on improving these aspects of the modelling and the consequences of crashes more than 2000 ft. but less than 10 miles from a runway end as well as impacts on third parties

Conceptual design for a receiving station for the nondestructive assay of PuO/sub 2/ at the fuels and materials examination facility

We propose a conceptual design for a receiving station for input accountability measurements on PuO/sub 2/ received at the Fuels and Materials Examination Facility at the Hanford Engineering Development Laboratory. Nondestructive assay techniques are proposed, including neutron coincidence counting, calorimetry, and isotopic determination by gamma-ray spectroscopy, in a versatile data acquisition system to perform input accountability measurements with precisions better than 1% at throughputs of up to 2 M.T./yr of PuO/sub 2/

Fourier transform ion cyclotron resonance MS reveals the presence of a water molecule in an enzyme transition-state analogue complex

The structures of several powerful inhibitors of hydrolytic enzymes resemble that of the altered substrate in the transition state, except that a hydrogen atom replaces one substituent (typically the leaving group). To test the hypothesis that a water molecule might be present in the gap resulting from this replacement, we examined a transition-state analogue complex formed by Escherichia coli cytidine deaminase by Fourier transform ion cyclotron resonance MS in electrospray mode. Upon nebularization from aqueous solution under conditions (pH 5.6) where the enzyme is active, cytidine deaminase remains dimeric in the vapor phase. In the presence of inhibitor, the enzyme's exact mass can be used to infer the presence at each active site of zinc, 5-fluoro-3,4-dihydrouridine, and a single water molecule