Occasional Finding Of Neurological Disorders During Children Hearing Loss Evaluation Using The Abr

One of the most important applications of the Brainstem evoked response audiometry (ABR) is in the evaluation of hearing loss in children. Today the ABR is also indicated in the screening of cochleovestibular syndromes to detect retrocochlear lesions, to monitor patients in a coma (brain death), in monitoring the brainstem during skull base surgery, etc. Among the many BERA qualities, is its capacity to evaluate the neurophysiologic integrity of the auditory brainstem pathway. In doing so, sometimes while evaluating hearing function in children we are faced with ABR waves that suggest the presence of retrocochlear lesions (trace asymmetry, increased interpeak intervals), many times confirmed through image studies. These cases are seen as occasional findings of neurologic disorders during children hearing loss evaluation. In this study we report 2 cases of neurologic disorders diagnosed with the use of the ABR to evaluate hearing loss in children. © Revista Brasileira de Otorrinolaringologia. All Rights reserved.733424428Jewett, D.L., Romano, M.N., Williston, J.S., Human auditory evoked potentials: Possible brain stem components detected on the scalp (1970) Science, 167 (924), pp. 1517-1518Starr, A., Hamilton, A.E., Correlation between confirmed sites of neurological lesions and abnormalities of far-field auditory brainstem responses (1976) Electroencephalogr Clin Neurophysiol, 41 (6), pp. 595-608Levine, R.A., Gardner, J.C., Fullerton, B.C., Stufflebeam, S.M., Carlisle, E.W., Furst, M., Effects of multiple sclerosis brainstem lesions on sound lateralization and brainstem auditory evoked potentials (1993) Hear Res, 68 (1), pp. 73-88Moller, A.R., Jannetta, P.J., Auditory evoked potentials recorded intracranially from the brain stem in man (1982) Exp Neurol, 78 (1), pp. 144-157Hashimoto, I., Ishiyama, Y., Yoshimoto, T., Nemoto, S., Brain-stem auditory-evoked potentials recorded directly from human brain-stem and thalamus (1981) Brain, 104 (PART 4), pp. 841-859Anson, B., Donaldson, J., (1981) Surgical anatomy of the temporal bone, , 3rd ed. Philadelphia: W.B. Saunders;Sousa LCA, Piza MRT, Costa SS. Poster: Brainstem Evoked Auditory Potential (ABR) in Neurology and Neurosurgery: 99th Meeting of the American Academy of Otolaryngology- Head and Neck Surgery. New Orleans, USA, Setembro1995Sousa, L.C.A., Piza, M.R.T., Costa, S.S., Diagnosis of Menières Disease: Routine and Extended Tests (2002) Otolaryngol Clin North Am, , JuneMarangos, N., Maier, W., Merz, R., Laszig, R., Brainstem response in cerebellopontine angle tumors (2001) Otol Neurotol, 22 (1), pp. 95-99Haapaniemi, J., Laurikainen, E., Jahansson, R., Rinne, T., Varpula, M., Audiovestibular findings and location of na acoustic neuroma (2000) Eur Arch Otorhinolaryngol, 257 (4), pp. 237-241Costa, S.S., Sousa, L.C.A., Cruz, O.L.M., Colli, B.O., Andrade, M.J., Rollin, G.A.F.S., Schwannoma vestibular: Apresentação atípica (1995) J Bras Neurosurg, 6 (2), pp. 41-48Sousa LCA, Piza MRT, Costa SS, Ferez M, Colli BO. Electrophysiologic Monitoring (ABR) of Coma Status,: 99th Meeting of the American Academy of Otolaryngology. Head and Neck Surgery, New Orleans, USA1995Coser, P.L., Menon, A.D., Electrophysiological study of auditory pathways and the vestibular system in tumor pathology of the 8th cranial nerve and of the cerebellopontile angle (1981) Rev Laryngol Otol Rhinol (Bord), 102 (5-6), pp. 239-24

PACCE: Perl Algorithm to Compute Continuum and Equivalent Widths

We present Perl Algorithm to Compute continuum and Equivalent Widths (pacce). We describe the methods used in the computations and the requirements for its usage. We compare the measurements made with pacce and "manual" ones made using iraf splot task. These tests show that for SSP models the equivalent widths strengths are very similar (differences <0.2A) for both measurements. In real stellar spectra, the correlation between both values is still very good, but with differences of up to 0.5A. pacce is also able to determine mean continuum and continuum at line center values, which are helpful in stellar population studies. In addition, it is also able to compute the uncertainties in the equivalent widths using photon statistics. The code is made available for the community through the web at http://www.if.ufrgs.br/~riffel/software.html.Comment: 8 pages, 5 figures, accepted by Astrophysics and Space Scienc

Screening and in silico characterization of prophages in Helicobacter pylori clinical strains

Publisher Copyright: © The AuthorsThe increase of antibiotic resistance calls for alternatives to control Helicobacter pylori, a Gram-negative bacterium associated with various gastric diseases. Bacteriophages (phages) can be highly effective in the treatment of pathogenic bacteria. Here, we developed a method to identify prophages in H. pylori genomes aiming at their future use in therapy. A polymerase chain reaction (PCR)-based technique tested five primer pairs on 74 clinical H. pylori strains. After the PCR screening, 14 strains most likely to carry prophages were fully sequenced. After that, a more holistic approach was taken by studying the complete genome of the strains. This study allowed us to identify 12 intact prophage sequences, which were then characterized concerning their morphology, virulence, and antibiotic-resistance genes. To understand the variability of prophages, a phylogenetic analysis using the sequences of all H. pylori phages reported to date was performed. Overall, we increased the efficiency of identifying complete prophages to 54.1 %. Genes with homology to potential virulence factors were identified in some new prophages. Phylogenetic analysis revealed a close relationship among H. pylori-phages, although there are phages with different geographical origins. This study provides a deeper understanding of H. pylori-phages, providing valuable insights into their potential use in therapy.proofinpres

The quantum J_{1}-J_{1'}-J_{2} spin-1/2 Heisenberg antiferromagnet: A variational method study

The phase transition of the quantum spin-1/2 frustrated Heisenberg antiferroferromagnet on an anisotropic square lattice is studied by using a variational treatment. The model is described by the Heisenberg Hamiltonian with two antiferromagnetic interactions: nearest-neighbor (NN) with different coupling strengths J_{1} and J_{1'} along x and y directions competing with a next-nearest-neighbor coupling J_{2} (NNN). The ground state phase diagram in the ({\lambda},{\alpha}) space, where {\lambda}=J_{1'}/J_{1} and {\alpha}=J_{2}/J_{1}, is obtained. Depending on the values of {\lambda} and {\alpha}, we obtain three different states: antiferromagnetic (AF), collinear antiferromagnetic (CAF) and quantum paramagnetic (QP). For an intermediate region {\lambda}_{1}<{\lambda}<1 we observe a QP state between the ordered AF and CAF phases, which disappears for {\lambda} above some critical value {\lambda}_{1}. The boundaries between these ordered phases merge at the quantum critical endpoint (QCE). Below this QCE there is again a direct first-order transition between the AF and CAF phases, with a behavior approximately described by the classical line {\alpha}_{c}{\simeq}{\lambda}/2

The discontinuous nature of chromospheric activity evolution

Chromospheric activity has been thought to decay smoothly with time and, hence, to be a viable age indicator. Measurements in solar type stars in open clusters seem to point to a different conclusion: chromospheric activity undergoes a fast transition from Hyades level to that of the Sun after about 1 Gyr of main--sequence lifetime and any decaying trend before or after this transition must be much less significant than the short term variations.Comment: 6 pages, 1 figure, to be published in Astrophysics and Space Scienc

Green functions for generalized point interactions in 1D: A scattering approach

Recently, general point interactions in one dimension has been used to model a large number of different phenomena in quantum mechanics. Such potentials, however, requires some sort of regularization to lead to meaningful results. The usual ways to do so rely on technicalities which may hide important physical aspects of the problem. In this work we present a new method to calculate the exact Green functions for general point interactions in 1D. Our approach differs from previous ones because it is based only on physical quantities, namely, the scattering coefficients, $R$ and $T$, to construct $G$. Renormalization or particular mathematical prescriptions are not invoked. The simple formulation of the method makes it easy to extend to more general contexts, such as for lattices of $N$ general point interactions; on a line; on a half-line; under periodic boundary conditions; and confined in a box.Comment: Revtex, 9 pages, 3 EPS figures. To be published in PR

Haematological and biochemical parameters in Churra-da-Terra-Quente ewes from the northeast of Portugal

Hematological and biochemical parameters, including plasma electrolytes and thyroid hormones, were determined in 73 clinically healthy Churra-da-Terra-Quente ewes, a typical breed from the northeast of Portugal. The hemogram values were: erythrocytes 9.8±1.51012/L; haemoglobin 118.1±19.1g/L; haematocrit 40.8±5.9%; leukocytes 5.7±1.8109/L; and platelets 544.3±177.2109/L. The thrombin time was 17.3±1.7 seconds. The values of biochemical parameters were: total protein 76.4±6.1g/L; glucose 2.87±0.60mmol/L; total cholesterol 1.65±0.33mmol/L; aspartate aminotransferase 155.9±49.2U/L; alanine aminotransferase 23.2±9.6U/L; γ-glutamyl transferase 48.0±18.7U/L; total alkaline phosphatase 121.6±76.1U/L; glutamate dehydrogenase 6.4±3.7U/L; urea 7.32±2.22mmol/L; creatinine 123.0±54.1μmol/L; total calcium 2.53±0.25mmol/L; phosphorus 2.10±0.46mmol/L; magnesium 1.01±0.09mmol/L; sodium 152.04±3.65mmol/L; potassium 4.7±0.4mmol/L; ionized calcium 1.32±0.07mmol/L; total thyroxine 111.75±42.29nmol/L; total triiodothyronine 1.01±0.28nmol/L; free T4 11.93±1.78pmol/L; free T3 4.22±1.33pmol/L; and thyroid-stimulating hormone 0.18±0.19μIU/mL. Although differences among the Churra-da-Terra-Quente breed and other breeds may occur, the hematological and biochemical parameters, plasma electrolytes, and thyroid hormones, for this indigenous breed, were generally situated within the reference intervals previously reported for sheep

Derivation of the human embryonic stem cell line RCe014-A (RC-10)

AbstractThe human embryonic stem cell line RCe014-A (RC-10) was derived from a fresh oocyte voluntarily donated as unsuitable and surplus to fertility requirements following ethics committee approved informed consent under licence from the UK Human Fertilisation and Embryology Authority. The cell line shows normal pluripotency marker expression and differentiation to the three germ layers in vitro. It has a mixed 46XY and 47XY +12 male karyotype and microsatellite PCR identity, HLA and blood group typing data is available