Congenital lobular capillary hemangioma of the nasal cavity of an infant - A rare case report

Introdução: O hemangioma capilar lobular (HCL), originalmente denominado como granuloma piogénico, é uma lesão vascular benigna de crescimento rápido de etiologia desconhecida, com uma distinta arquitectura microscópica lobular, que afecta a pele e mucosa. Embora o HCL da cabeça e pescoço não seja incomum, a sua ocorrência na fossa nasal é pouco frequente, e ainda mais raro em crianças. Material e métodos: Estudo retrospectivo de caso clínico de um lactente com uma massa na fossa nasal direita diagnosticada como HCL, utilizando o método descritivo. Resultados: Esta é uma revisão da história de um lactente com 54 dias de idade referenciado ao nosso hospital por obstrução nasal severa causada por uma massa da fossa nasal direita. A criança apresentava dificuldade respiratória desde o nascimento, que se foi agravando progressivamente à medida que a massa aumentava de tamanho. Esta estava a ser responsável pelo abaulamento do lado direito da pirâmide nasal e septo e pelo aparecimento de edema periorbitário à direita. Após remoção da massa através de cirurgia endoscópica nasal, foi feito o diagnóstico histológico de HCL. Conclusões: Os autores encontraram apenas a descrição de um caso na literatura de um HCL congénito da fossa nasal num lactente. Embora raro, o HCL deve ser incluído no diagnóstico diferencial de massas das fossas nasais na população pediátrica.info:eu-repo/semantics/publishedVersio

Atypical Presentations of Hearing Loss in Patients with Acoustic Neuroma

A hipoacúsia neurosensorial unilateral e progressiva é uma das principais manisfestações audiológicas dos doentes com diagnóstico de neurinoma do acústico, estando no entanto descritas outras formas de apresentação. Dos 43 doentes com diagnóstico de neurinoma do acústico, tratados pela equipa de otoneurocirurgia entre 1997 e 2003, identificamos 88,5% com hipoacústica neurosensorial unilateral, 4,6% como hipoacústica neurosensorial súbita, 4,6% com audição simétrica e 2,3% com audição "normal". Estes dados revelam a existência de três formas incomuns de apresentação dos neurinomas, facto que deve levar os otorrinolaringologistas a manterem um elevado grau de alerta perante doentes com queixas que possam sugerir, de algum modo, a presença de neurinoma do acústico

Enhancing Fault / Intrusion Tolerance through Design and Configuration Diversity

Fault/intrusion tolerance is usually the only viable way of improving the system dependability and security in the presence of continuously evolving threats. Many of the solutions in the literature concern a specific snapshot in the production or deployment of a fault-tolerant system and no immediate considerations are made about how the system should evolve to deal with novel threats. In this paper we outline and evaluate a set of operating systems’ and applications’ reconfiguration rules which can be used to modify the state of a system replica prior to deployment or in between recoveries, and hence increase the replicas chance of a longer intrusion-free operation

Impact of cognitive intervention on cognitive symptoms and quality of life in idiopathic Parkinson’s disease: a randomized and controlled study

Pharmacological treatments for mild cognitive impairment (MCI), are lacking, and alternative approaches have been implemented, including cognitive training (CT). Objective: To determine the impact of CT on cognitive and quality of life measures in patients with Parkinson’s disease (PD) who were seen a hospital neurorehabilitation program. Methods: Thirty-nine individuals with MCI-PD, according to the Movement Disorder Society, were randomly distributed into two groups: experimental and control group, matched for demographic and clinical characteristics. Both groups were assessed for cognition and quality of life at the beginning of the study and at the end of the intervention protocol. The following instruments were used to assess cognition and quality of life: Addenbrooke’s Cognitive Examination III, Digit Span, Trail Making Test (TMT, A and B) and Parkinson disease quality of life questionnaire. The experimental group (EG) engaged in CT, whereas the control group (CG) underwent activities of the general rehabilitation program. Results: No baseline evaluation differences were found. Intergroup analysis showed differences in measures, such as total score (1.977, p=0.0480) and visuospatial domain (-2.636, p=0.0084) of the ACE-III, with the EG performing better, in addition to better performance in TMT-B mistakes (-1.928, p=0.0439). Intragroup analysis revealed that the EG showed significant improvement in almost all the cognitive variables, well as in self-reported quality of life (total score and mobility, activities of daily living, body discomfort dimensions). Conclusions: Engagement in cognitive activities was associated with better cognitive abilities in PD-MCI. Future studies should consider the long-term effect of this type of intervention and impact on functional activities

Differences in the macrozoobenthic fauna colonising empty bivalve shells before and after invasion by Corbicula fluminea

Bivalve shells can potentially alter the structure of aquatic benthic communities. However, little is known about the effect that different shell morphologies have on their associated fauna. This study aimed to understand how empty shells, from four different freshwater bivalve species, affect macrozoobenthic communities, using the River Minho (Iberian Peninsula) as a study area. Three native (Anodonta anatina, Potomida littoralis, Unio delphinus) and one non-indigenous (Corbicula fluminea) species were used for this research. Comparisons among species and between scenarios (i.e. before and after invasion by C. fluminea) were performed. Our results suggest that macrozoobenthic community structure did not vary among treatments, with the exception of species richness, which was higher on shells of native species. Furthermore, little difference was detected when comparing scenarios with and without C. fluminea shells, despite dissimilarities in size and morphology between species. The empty shells of C. fluminea partially (in terms of density and biomass, but not in species richness) replaced the role of empty shells of native species as a physical substratum for the associated macrozoobenthic community.Martina Ilarri is supported by a Post-doc grant (SFRH/BPD/90088/2012) from the Portuguese Foundation for Science and Technology – FCT through POPH/FSE funds. This study was conducted within the scope of the project ECO-IAS: Ecosystem-level impacts of an invasive alien species, supported by FCT and COMPETE funds (contract: PTDC/AAC-AMB/116685/2010) and was also partially supported by the European Regional Development Fund (ERDF) through COMPETE funds (PEst-C/MAR/LA0015/2011) and by FCT/MEC through Portuguese funds (PIDDAC – PEst-OE/BIA/UI4050/2014).info:eu-repo/semantics/publishedVersio

Rock Slopes from Mechanics to Decision Making

http://lmrwww.epfl.ch/Eurock/Eurock2010/files/papers%20grouped.pdfRock slope instabilities are discussed in the context of decision making for risk assessment and management. Hence, the state of the slope and possible failure mechanism need to be defined first. This is done with geometrical and mechanical models for which recent developments are presented. This leads with appropriate consideration of uncertainties to risk determination and to the description of tools for risk management through active and passive countermeasures, including warning systems. The need for sensitivity analysis is then demonstrated, and final comments address updating through information collection.National Science Foundation (U.S.)MIT-Portugal ProgramPortuguese Science and Technology FoundationNorwegian Geotechnical Institute (International Centre for Geohazards)United States. Dept. of Energ

Ecologia reprodutiva de Ocotea porosa (Ness & Mart.) Barroso (Lauraceae).

Resumo

Phaeochromocytoma Associated to Von Recklinghausen Neurofibromatosis Type I: a Rare Clinical Case

Os feocromocitomas são neoplasias originárias das células cromafins da crista neural localizados, na sua grande maioria, na medula supra-renal, podendo também aparecer nos gânglios simpáticos (paragangliomas). Ocorrem de forma esporádica em 90% dos casos; contudo, em cerca de 10% são um componente de síndromes neoplásicas de transmissão autossómica dominante, como a doença de von Hippel-Lindau, a neoplasia endócrina múltipla tipo 2 (MEN 2) e, mais raramente, associados à Neurofibromatose de von Recklinghausen tipo I (3-5%). A este propósito, os autores apresentam o caso de um homem de 54 anos, com uma história pessoal e familiar de Neurofibromatose de von Recklinghausen tipo I em que foi detectado um tumor da supra-renal direita, assintomátic(“incidentaloma”), cuja investigação posterior comprovou ser um feocromocitoma produtor de elevados níveis de epinefrina e nor-epinefrina. Apesar do padrão secretório de catecolaminas apresentado, foi confirmada, por pressurometria de 24 horas, a existência de normotensão e ausência de história familiar de hipertensão arterial, factos igualmente pouco comuns. Discutem-se alguns dos mecanismos patogénicos envolvidos nestas entidades sindromáticas tumorais, bem como o seu comportamento clínico; salienta-se, igualmente, a importância do rastreio oncológico sistemático, nomeadamente de feocromocitomas, em familiares de indivíduos portadores deste tipo de neoplasia autossómica dominante, mesmo que assintomáticos

Chemical abundances of 1111 FGK stars from the HARPS GTO planet search program II: Cu, Zn, Sr, Y, Zr, Ba, Ce, Nd and Eu

To understand the formation and evolution of the different stellar populations within our Galaxy it is essential to combine detailed kinematical and chemical information for large samples of stars. We derive chemical abundances of Cu, Zn, Sr, Y, Zr, Ba, Ce, Nd and Eu for a large sample of more than 1000 FGK dwarf stars with high-resolution ($R \sim$\,115000) and high-quality spectra from the HARPS-GTO program. The abundances are derived by a standard Local Thermodinamyc Equilibrium (LTE) analysis using measured Equivalent Widths (EWs) injected to the code MOOG and a grid of Kurucz ATLAS9 atmospheres. We find that thick disk stars are chemically disjunct for Zn and Eu and also show on average higher Zr but lower Ba and Y when compared to the thin disk stars. We also discovered that the previously identified high-$\alpha$ metal-rich population is also enhanced in Cu, Zn, Nd and Eu with respect to the thin disk but presents Ba and Y abundances lower on average, following the trend of thick disk stars towards higher metallities and further supporting the different chemical composition of this population. The ratio of heavy-s to light-s elements of thin disk stars presents the expected behaviour (increasing towards lower metallicities) and can be explained by a major contribution of low-mass AGB stars for s-process production at disk metallicities. However, the opposite trend found for thick disk stars suggests that intermediate-mass AGB stars played an important role in the enrichment of the gas from where these stars formed. Previous works in the literature also point to a possible primary production of light-s elements at low metallicities to explain this trend. Finally, we also find an enhancement of light-s elements in the thin disk at super solar metallicities which could be caused by the contribution of metal-rich AGB stars. (short version)Comment: 20 pages, 19 figures, accepted by A&