The days of plenty might soon be over in glacierized Central Asian catchments

Despite the fact that the fast-growing population of Central Asia strongly depends on glacial melt water for fresh water supply, irrigation and hydropower production, the impact of glacier shrinkage on water availability remains poorly understood. With an annual area loss of 0.36 to 0.76%, glaciers are retreating particularly fast in the northern Tien Shan, thus causing concern about future water security in the densely populated regions of Bishkek and Almaty. Here, we use exceptionally long in-situ data series to run and calibrate a distributed glacio-hydrological model, which we then force with downscaled data from phase five of the Climate Model Intercomparison Project CMIP5. We observe that even in the most glacier-friendly scenario, glaciers will lose up to two thirds (−60%) of their 1955 extent by the end of the 21st century. The range of climate scenarios translates into different changes in overall water availability, from peak water being reached in the 2020s over a gradual decrease to status quo until the end of the 21st century. The days of plenty, however, will not last much longer, as summer runoff is projected to decrease, independent of scenario uncertainty. These results highlight the need for immediate planning of mitigation measures in the agricultural and energy sectors to assure long-term water security in the densely populated forelands of the Tien Shan

Identification of genetic elements in metabolism by high-throughput mouse phenotyping.

Metabolic diseases are a worldwide problem but the underlying genetic factors and their relevance to metabolic disease remain incompletely understood. Genome-wide research is needed to characterize so-far unannotated mammalian metabolic genes. Here, we generate and analyze metabolic phenotypic data of 2016 knockout mouse strains under the aegis of the International Mouse Phenotyping Consortium (IMPC) and find 974 gene knockouts with strong metabolic phenotypes. 429 of those had no previous link to metabolism and 51 genes remain functionally completely unannotated. We compared human orthologues of these uncharacterized genes in five GWAS consortia and indeed 23 candidate genes are associated with metabolic disease. We further identify common regulatory elements in promoters of candidate genes. As each regulatory element is composed of several transcription factor binding sites, our data reveal an extensive metabolic phenotype-associated network of co-regulated genes. Our systematic mouse phenotype analysis thus paves the way for full functional annotation of the genome

Influence of Temperature on the Corrosion behaviour of Stainless Steels under Tribological Stress

Posterpräsentatio

Edelstahl Rostfrei - Nachhaltige Substitution bei Fischzuchtnetzen

In beispielhafter Zusammenarbeit zwischen Industrie (Geobrugg AG, Romanshorn/Schweiz) und Wissenschaft (WITg Institut für Werkstoffsystemtechnik Thurgau an der Hochschule Konstanz, Tägerwilen/Schweiz) wurde mit Unterstützung der Schweizer staatlichen Innovationsförderung (KTI, hee Innosuisse) ein neues Werkstoff- und Fertigungskonzept für den Bau von Fischzuchtnetzen aus hochfesten nichtrostenden Stahldrähten entwickelt. Diese Entwicklung wurde 2019 von Swiss Inox, der Schweizer Innovationspreis Prix Inox ausgezeichnet

Application of high strengh duplex stainless steel wire for offshore fish farming cages and geological protection systems

Fachvortrag auf der 10th International European Stainless Steel Conference and 6th European Duplex Stainless Steel Conference (ESSC & DUPLEX 2019), 30.09. – 02.10.2019, Vienna, Austri

Überwachung der Korrosion von Schutzverbauungen

Die Geobrugg AG hat zusammen mit dem Institut für Werkstoffsystemtechnik Thurgau (WITg) ein digitales Monitoringsystem entwickelt, das zum einen die Korrosion der Bauwerke überwacht, zum anderen auch die mechanische Einwirkung auf die Verbauung registriert

Corrosion resistance and impact strength effected by wall thickness of powder metallugrical S2205 duplex stainless steel

Paper 85661, Abstrac