Lansbury MicroMuseum in Urban Rooms: Civic Schools & City Learning. Past, Present and Future

Our contribution formed part of an exhibition exploring the past, present and future of urban rooms and civic schools in the UK to inform the vision for UCL’s Urban Room at UCL's new campus in the Queen Elizabeth Olympic Park, Stratford. The event brought together practitioners and thinkers of different generations who have worked to engage people with their surroundings in order to discuss further action, and to uncover their history, discuss current iterations and explore future possibilities

Late Maastrichtian to Danian organic-walled dinoflagellate cysts and calcareous nannofossils from eastern Austral Basin, Patagonia, Argentina

Late Maastrichtian to Danian dinoflagellate cyst and calcareous nannofossil biostratigraphy was analyzed at the Sur Río Chico borehole, Austral Basin, Argentina. Two stratigraphical intervals from the 965 to 1003 m below ground surface of the drilled section were defined. The co-occurrence of Manumiella bertodano, M. seelandica and M. conorata in the 990–1000 to 1000–1003 mbgs interval, associated with the top of the nannofossil Neprolithus frequens miniporus Zone indicated a late (probably latest) Maastrichtian age. The acme of the presumed heterotrophic Manumiella spp. and the acme of the mesotrophic cool-water nannofossil Prediscosphaera stoveri, together with other cool-water taxa Arkhangelskiella cymbiformis, Kamptnerius magnificus and Nephrolithus frequens may indicate cool nutrient–rich waters in this interval. Finally, the co-occurrence of dinoflagellate cyst taxa Carpatella cornuta, Cerodinium diebelii, Danea californica, Senoniasphaera inornata and Palaeoperidinium pyrophorum linked to the nannofossil NP3 Zone, suggest a middle Danian age for the 965–970 to 985–990 mbgs interval. An acme of P. pyrophorum herein related to the Pp2 of New Zealand, might reflect an episode of cool temperature during the Danian in the Austral Basin. The sedimentary succession is represented by the Campo Bola Formation within which two discontinuities were recognized; the older is of early-late Maastrichtian, and the younger is of the latest Maastrichtian to the earliest Danian. A third discontinuity involving the middle to late Paleocene separates the Campo Bola Formation from the overlain Eocene Man Aike Formation.Fil: González Estebenet, María Sol. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto Geológico del Sur. Universidad Nacional del Sur. Departamento de Geología. Instituto Geológico del Sur; ArgentinaFil: Guler, Maria Veronica. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto Geológico del Sur. Universidad Nacional del Sur. Departamento de Geología. Instituto Geológico del Sur; ArgentinaFil: Perez Panera, Juan Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. YPF - Tecnología; Argentin

Evolution of stellar population: Environments vs galaxy interactions

Several authors have studied the dependence of galaxy properties on environment in order to understand which mechanisms operate in the galaxy evolution. Recently, some of them have proposed that intermediate densities could be sites where local environment influences the transition of galaxies onto the red-sequence, as opposed to mechanisms that operate on cluster scales. Based on the evidence that interacting and merging systems are frequent at intermediate densities, we use the SDSS-DR4 data to analyse the role of close galaxy interactions as an environmental process which could contribute to lead evolutionary transformations. We explore the properties of galaxy pairs at different local and global density environments, comparing them with those of isolate galaxies in an unbiased control sample (CS).Facultad de Ciencias Astronómicas y Geofísica

Plant-based vaccine for livestock : key points to unleash platform translation in developing countries

Ten years ago the first plant-based vaccine was licensed (DowAgrosciences). It was only 20 years after the first report of a recombinant protein obtained through plant transformation technology. Back then, this vaccine was perceived as the first of an unlimited list of innovative products of a flourishing platform. Unexpectedly, since then, no other veterinary product based on plant molecular pharming (PMP) has reached the market. This review will reflect a transdisciplinary view of the status and challenges that the molecular farming platform faces to become a strategic solution for the agroindustrial sector of developing countries. Recent findings Plant-based veterinary vaccines (PBVV) have the potential to give answers to several challenges that animal health presents today. The urgent need to improve livestock productivity, especially in low and middle-income countries (LMIC), and the current concern about the emergence of antimicrobial resistance associated with animal production, demands new products such as inexpensive vaccines and therapeutics. Based on the translational research scheme, certain barriers that could have limited the development into products of many results obtained in the last 15 years were identified. Summary Unquestionably, the development of innovation in LMIC is a key element in the feasibility of the platform. The emergence of PPP between multiple stakeholders as a strategy to overcome the existing disconnection between academia and industry, could enable the conversion of leading vaccine candidates from the stage of proof of concept into prototypes for industry, and thereby foster ‘productization’ in the field of veterinary vaccines.Inst. de PatobiologíaFil: Perez Aguirreburualde, Maria Sol. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; ArgentinaFil: Petruccelli, Silvana. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; ArgentinaFil: Bravo Almonacid, Fernando Felix. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular; ArgentinaFil: Wigdorovitz, Andrés. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

Evolution of stellar population: Environments vs galaxy interactions

Several authors have studied the dependence of galaxy properties on environment in order to understand which mechanisms operate in the galaxy evolution. Recently, some of them have proposed that intermediate densities could be sites where local environment influences the transition of galaxies onto the red-sequence, as opposed to mechanisms that operate on cluster scales. Based on the evidence that interacting and merging systems are frequent at intermediate densities, we use the SDSS-DR4 data to analyse the role of close galaxy interactions as an environmental process which could contribute to lead evolutionary transformations. We explore the properties of galaxy pairs at different local and global density environments, comparing them with those of isolate galaxies in an unbiased control sample (CS).Facultad de Ciencias Astronómicas y Geofísica

Actualización en diarrea viral bovina, herramientas diagnósticas y estrategias de prevención

El virus de la diarrea viral bovina (VDVB) es uno de los agentes involucrados en los complejos respiratorio y reproductivo bovino y ocasiona importantes pérdidas econó- micas a nivel mundial. El VDVB pertenece al género Pestivirus, dentro de la familia Flaviviridae y se clasifica en dos genotipos denominados VDVB-1 y VDVB-2, según su secuencia génica. Dentro del VDVB-1 se han descripto 15 subgenotipos diferentes (a-p) (Nagai et al., 2008; Yilmaz et al., 2012) y dentro del VDVB-2 hay 3 subgenotipos (a-c) (Flores et al., 2002). El VDVB es endémico en casi todo el mundo, prevaleciendo diferentes genotipos según las distintas regiones geográficas (Yeşilbağ, 2017).. Recientemente, una nueva variante, denominada VDVB-3 o “Virus HoBi-like”, ha sido aislada en países como Brasil, Italia, Tailandia e India, entre otros (Pecora et al., 2016); este patógeno no ha sido aislado en Argentina hasta el momento. Sin embargo, a partir de muestras bubalinas del noreste argentino se ha encontrado evidencia serológica de la circulación de esta variante viral (Pecora et al., 2016).Fil: Pecora, Andrea. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; ArgentinaFil: Pérez Aguirreburualde, María Sol. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentin

Análisis de la Estética Fotográfica de la obra de Giuseppe Falla y Liz Tasa

Se realizó una investigación cuyo propósito fue valorar la estética fotográfica de la obra de Giuseppe Falla y Liz Tasa, así mismo analizar los elementos técnicos, identificar los elementos simbólicos y comparar la fotografía de autor, por ello se aplicó un diseño no experimental básico transversal con un tipo de investigación cualitativa descriptiva, en la cual se eligieron 120 fotografías considerando la evolución de la estética fotográfica por etapas en un lapso de nueve años, además de la selección por temática y por autor; esta muestra fue dividida en dos grupos para analizar 60 imágenes por fotógrafo. Se utilizó una matriz de observación como instrumento para analizar e interpretar tanto los elementos técnicos y simbólicos, siendo validada por expertos del campo fotográfico. Los resultados demostraron que mediante el análisis y la interpretación de los elementos fotográficos se valora la estética de la fotografía de manera diferente, por un lado, está la belleza de las obras de Giuseppe que se dan con la expresión corporal de las personas y el uso de tonos cálidos, enfocándose en brindar protagonismo al modelo, por lo contrario, Liz resalta una belleza orientada en las expresiones faciales y corporales de los sujetos dentro de un contexto específico que puede ser un problema social o un evento costumbrista.TesisComunicación y desarrollo human

In vitro and in vivo characterization of a typical and a high pathogenic bovine viral diarrhea virus type ii strains

Non-cytopathic (ncp) type 2 bovine viral diarrhea virus (BVDV-2) is widely prevalent in Argentina causing high mortality rates in cattle herds. In this study, we characterized an Argentinean ncp BVDV-2 field isolate (98-124) compared to a high-virulence reference strain (NY-93), using in silico analysis, in vitro assays, and in vivo infections of colostrum-deprived calves (CDC) to compare pathogenic characters and virulence. In vitro infection of bovine peripheral blood mononuclear cells (PBMC) with BVDV 98-124 induced necrosis shortly after infection while NY-93 strain increased the apoptotic rate in infected cells. Experimental infection of CDC (n = 4 each) with these strains caused an enteric syndrome. High pyrexia was detected in both groups. Viremia and shedding were more prolonged in the CDC infected with the NY-93 strain. In addition, NY-93 infection elicited a severe lymphopenia that lasted for 14 days, whereas 98-124 strain reduced the leukocyte counts for 5 days. All infected animals had a diminished lymphoproliferation activity in response to a mitogen. Neutralizing and anti-NS3 antibodies were detected 3 weeks after infection in all infected calves. Virulence was associated with a more severe clinical score, prolonged immune-suppression, and a greater window for transmission. Studies of apoptosis/necrosis performed after in vitro PBMC infection also revealed differences between both strains that might be correlated to the in vivo pathogenesis. Our results identified 98-124 as a low-virulence strain.Instituto de VirologíaFil: Malacari, Darío Amilcar. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; ArgentinaFil: Pecora, Andrea. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; ArgentinaFil: Pérez Aguirreburualde, María Sol. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; ArgentinaFil: Cardoso, Nancy. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Odeon, Anselmo Carlos. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; ArgentinaFil: Capozzo, Alejandra. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

Sexo seguro: lo que tenés que saber de gonorrea y otras infecciones de Transmisión Sexual

¿Qué son las Infecciones de transmisión sexual? ¿Porqué son importantes? ¿Qué debemos saber de ellas? Este artículo intenta responder esas preguntas. Las Infecciones de Transmisión Sexual (ITS) involucran la transmisión de un organismo (microorganismo) entre parejas sexuales, a través de diferentes vías de contacto: oral, vaginal, anal. Estas ITS, en algunos casos, pueden desarrollar enfermedades, también conocidas como Enfermedades de Transmisión Sexual (ETS). Algunas de esas infecciones son curables, otras tratables, y todas son prevenibles. Las ITS son un problema de salud pública mundial, que va en aumento cada año. De acuerdo a un relevamiento reciente de la Organización Mundial de la Salud (OMS) hay un millón de contagios diarios de las ITS curables más importantes (clamidia, gonorrea, sífilis y tricomoniasis) (1). En el año 2016, se llegó a la cifra de 376 millones de contagios en un solo año. Las infecciones virales van en la misma tendencia, aún con cifras mayores (2) Estas infecciones, pueden causar complicaciones en la salud de la población, que van desde patologías crónicas a graves, y aumentando el riesgo de adquirir el virus de inmunodeficiencia humana (HIV). Para prevenirlas, la mejor estrategia es el conocimiento. Conocer su naturaleza, cómo se contagian, cómo se previenen, cómo se diagnostican y cómo se tratan, es el primer paso que podemos dar, y es el motivo del presente artículo. Las estrategias públicas de prevención y detección, las campañas de prevención oficiales, la educación sexual integral en los diferentes ámbitos académicos, son estrategias necesarias e imprescindibles para la disminución de contagio

MYH9-related disease : it does exist, may be more frequent than you think and requires specific therapy

Altres ajuts: Sources of support: FIS/Fondos FEDER (REDinREN RD016/0009), Sociedad Española de Nefrología, FRIAT, Comunidad de Madrid en Biomedicina B2017/BMD-3686 CIFRA2-CM. Salary support: ISCIII Rio Hortega to M.V.P.-G.In this issue of ckj, Tabibzadeh et al. report one of the largest series of patients with MYH9 mutations and kidney disease. The cardinal manifestation of MYH9-related disease is thrombocytopenia with giant platelets. The population frequency of pathogenic MYH9 mutations may be at least 1 in 20 000. The literature abounds in misdiagnosed cases treated for idiopathic thrombocytopenic purpura with immune suppressants and even splenectomy. Additional manifestations include neurosensorial deafness and proteinuric and hematuric progressive kidney disease (at some point, it was called Alport syndrome with macrothrombocytopenia), leucocyte inclusions, cataracts and liver enzyme abnormalities, resulting in different names for different manifestation combinations (MATINS, May-Hegglin anomaly, Fechtner, Epstein and Sebastian syndromes, and deafness AD 17). The penetrance and severity of kidney disease are very variable, which may obscure the autosomal dominant inheritance. A correct diagnosis will both preclude unnecessary and potentially dangerous therapeutic interventions and allow genetic counselling and adequate treatment. Morphological erythrocyte, granulocyte and platelet abnormalities may allow the future development of high-throughput screening techniques adapted to clinical peripheral blood flow cytometers