391 research outputs found

    Characterisation and textural analysis of Middle Bronze Age Transdanubian inlaid wares of the Encrusted Pottery Culture, Hungary: a preliminary study

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    Inlaid ceramics belonging to the Encrusted Pottery Culture and dated to the Middle Bronze Age (2000–1500 BC) are highly distinctive vessels with complex decorative motifs found in large numbers in the Transdanubia region of Hungary. Despite this considerable corpus of material there has been little systematic investigation of the composition of the inlays. Micro-analysis of Transdanubian inlaid wares by X-ray diffraction (XRD), micro-Fourier transform infrared microscopy (FT-IR), and scanning electron microscopy (SEM) provides new compositional, structural and textural information on the inlays. In contrast to common statements in the literature regarding the materials used to make inlays, these new data show that the majority of inlays are composed of hydroxyapatite (bone) that was previously ashed, although some of the inlays are composed of calcium carbonate. Additional compositional and textural variation in the bone inlays suggests that bone material from different skeletal elements and/or of different age may have been used, and that contrasting recipes for inlay preparation were employed during fabrication. These results suggest that the production of inlaid vessels of the Encrusted Pottery Culture was more complex than has hitherto been thought

    The effect of population variation on the accuracy of sex estimates derived from basal occipital discriminant functions

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    Multiple discriminant functions that estimate sex from the dimensions of the basal occipital have been published. However, as there is limited exploration of basal dimension variation between groups, the accuracy of these functions when applied to archaeological material is unknown. This study compares basal dimensions between four known sex-at-death post-medieval European samples and explores how metric differences impact on the accuracy of sex assessment discriminant functions. Published data from St Bride’s, London (n = 146) and the Georges Olivier collection, Paris (n = 68) were compared with new data from the eighteenth to nineteenth century Dutch Middenbeemster sample (n = 74) and the early twentieth century Rainer sample, Romania (n = 282) using independent t tests. The Middenbeemster and Rainer data were substituted into six published discriminant functions derived from the St Bride’s and the Georges Olivier samples, and the results were compared to their known sex. Multiple statistically significant differences were found between the four groups. Of the six discriminant functions tested, five failed to reach the published accuracy and fell below chance. In addition, even where the samples were statistically comparable in means, trends for difference also impacted the accuracy of discriminant functions. Enough variation in basal occipital dimensions existed in the European groups to decrease the accuracy of sex estimation discriminant functions to unusable. Possible inter-observer error, varying genetic, socioeconomic, and geographical factors are likely causes of dimension variation. This research further highlights the dangers of using sex estimation discriminant functions on samples that differ to the original derivative population and demonstrates the need for more rigorous testing

    The stigmatisation of people with chronic back pain

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    This study responded to the need for better theoretical understanding of experiences that shape the beliefs, attitudes and needs of chronic back patients attending pain clinics. The aim was explore and conceptualise the experiences of people of working age who seek help from pain clinics for chronic back pain. Methods. This was a qualitative study, based on an interpretative phenomenological approach (IPA). During in-depth interviews in their homes, participants were invited to 'tell their story' from the time their pain began. Participants were twelve male and six female patients, aged between 28 and 62 years, diagnosed as having chronic benign back pain. All had recently attended one of two pain clinics as new referrals. The interview transcripts were analysed thematically. Findings. Stigmatisation emerged as a key theme from the narrative accounts of participants. The findings expose subtle as well as overt stigmatising responses by family, friends, health professionals and the general public which appeared to have a profound effect on the perceptions, self esteem and behaviours of those interviewed. Conclusions. The findings suggest that patients with chronic back pain feel stigmatised by the time they attend pain clinics and this may affect their attitudes and behaviours towards those offering professional help. Theories of chronic pain need to accommodate these responses, while pain management programmes need to address the realities and practicalities of dealing with stigma in everyday life

    Distinct Impacts of Eda and Edar Loss of Function on the Mouse Dentition

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    The Eda-A1-Edar signaling pathway is involved in the development of organs with an ectodermal origin, including teeth. In mouse, mutants are known for both the ligand, Eda-A1 (Tabby), and the receptor, Edar (Downless). The adult dentitions of these two mutants have classically been considered to be similar. However, previous studies mentioned differences in embryonic dental development between EdaTa and Edardl-J mutants. A detailed study of tooth morphology in mutants bearing losses of functions of these two genes thus appears necessary to test the pattern variability induced by the developmental modifications. 3D-reconstructions of the cheek teeth have been performed at the ESRF (Grenoble, France) by X-ray synchrotron microtomography to assess dental morphology. The morphological variability observed in EdaTa and Edardl-J mutants have then been compared in detail. Despite patchy similarities, our detailed work on cheek teeth in EdaTa and Edardl-J mice show that all dental morphotypes defined in Edardl-J mice resolutely differ from those of EdaTa mice. This study reveals that losses of function of Eda and Edar have distinct impacts on the tooth size and morphology, contrary to what has previously been thought. The results indicate that unknown mechanisms of the Eda pathway are implicated in tooth morphogenesis. Three hypotheses could explain our results; an unexpected role of the Xedar pathway (which is influenced by the Eda gene product but not that of Edar), a more complex connection than has been appreciated between Edar and another protein, or a ligand-independent activity for Edar. Further work is necessary to test these hypotheses and improve our understanding of the mechanisms of development

    General practitioners' perceptions on home medicines reviews: A qualitative analysis

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    Background: Home Medicines Review (HMR) is an Australian initiative introduced in 2001 to improve quality use of medicines. Medication management services such as HMRs have the potential to reduce medication related problems. In 2011, changes to the HMR program were introduced to allow for referrals directly to accredited pharmacists in addition to the community pharmacy referral model. These changes were introduced to improve efficiency of the process. This study explored the perceptions of Western Australian general practitioners (GPs) on benefits and barriers of the HMR service and process, including their insights into the direct referral model. Methods: Purposive sampling of GPs who had experience ensured that participants had a working knowledge of the HMR service. Semi structured interviews with 24 GPs from 14 metropolitan Western Australian medical centres between March and May 2013. Transcribing and thematic analysis of data were performed. Results: Most GPs had positive attitudes towards the HMR service. Main perceived benefits of the service were poly-pharmacy reduction and education for both the GP and patient. Strategies identified to improve the service were introduction of a standard HMR report template for pharmacists and better use of technology. Whilst reliability and GPs' familiarity were the main perceived benefits of the direct referral model, a number of GPs agreed that patient unfamiliarity with the HMR pharmacist was a barrier. Conclusions: Despite recognition of the value of the HMR service participating GPs were of the opinion that there are aspects of the HMR service that could be improved. As one of the success factors of HMRs is relying on GPs to utilise this service, this study provides valuable insight into issues that need to be addressed to improve HMR uptake

    Learning lessons from the 2011 Van Earthquake to enhance healthcare surge capacity in Turkey

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    Historically, Turkey has adopted a reactive approach to natural hazards which resulted in significant losses. However, following the 1999 Kocaeli Earthquake, a more proactive approach has been adopted. This study aims to explore the way this new approach operates on the ground. A multi-national and multi-disciplinary team conducted a field investigation following the 2011 Van Earthquake to identify lessons to inform healthcare emergency planning in Turkey and elsewhere. The team interviewed selected stakeholders including, healthcare emergency responders, search and rescue services, ambulance services, and health authority representatives, in addition to conducting a focus group. Data were analysed according to an open coding process and SWOT analysis. The findings suggest that the approach succeeded in developing a single vision by consolidating official efforts in a more structured way, mobilising many governmental and non-governmental organisations, securing significant amounts of resources including physical and human, and increasing the resilience and flexibility of infrastructure to expand its capacity. However, more attention is required to the development of stronger management procedures and acquisition of further resources

    How Can Home Care Patients and Their Caregivers Better Manage Fall Risks by Leveraging Information Technology?

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    Objectives: From the perspectives of home care patients and caregivers, this study aimed to (a) identify the challenges for better fall-risk management during home care episodes and (b) explore the opportunities for them to leverage health information technology (IT) solutions to improve fall-risk management during home care episodes. Methods: Twelve in-depth semistructured interviews with the patients and caregivers were conducted within a descriptive single case study design in 1 home health agency (HHA) in the mid-Atlantic region of the United States. Results: Patients and caregivers faced challenges to manage fall risks such as unmanaged expectations, deteriorating cognitive abilities, and poor care coordination between the HHA and physician practices. Opportunities to leverage health IT solutions included patient portals, telehealth, and medication reminder apps on smartphones. Conclusion: Effectively leveraging health IT could further empower patients and caregivers to reduce fall risks by acquiring the necessary information and following clinical advice and recommendations. The HHAs could improve the quality of care by adopting IT solutions that show more promise of improving the experiences of patients and caregivers in fall-risk management
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