IDADE U-Th-PbT DE MONAZITAS DO SILLIMANITA-CORDIERITA-GRANADA-BIOTITA GNAISSE DE ITAPECERICA (MG) E A ATUAÇÃO DA OROGENIA RIACIANO-OROSIRIANA NO INTERIOR DO CRATON SÃO FRANCISCO MERIDIONAL

Na mina da empresa Nacional de Grafite em Itapecerica (MG), localizada no interior do Craton São Francisco Meridional, ocorre uma associação de rochas paraderivadas de alto grau metamórfico que inclui gnaisses, quartzitos e grafita xistos, além de granitoides peraluminosos. Provenientes de um sillimanita-cordierita-granada-biotita gnaisse desta associação, cristais de monazita internamente homogêneos tiveram suas composições químicas determinadas nas suas porções de borda e centro através da microssonda eletrônica. Os seus teores de U, Th e Pb permitiram a obtenção de uma idade química média (não isotópica) orosiriana de 2010 +/- 19 Ma, que parece indicar que as monazitas tenham sido geradas durante o metamorfismo de alto grau da transição das fácies anfibolito/granulito relacionado às últimas fases da Orogenia Riaciano-Orosiriana regional. Estas monazitas guardam o registro da atuação desta orogenia bem no interior do Craton São Francisco Meridional, junto aos limites externos da Província Sul Mineira paleoproterozóica

Modelagem de Dados Geofísico-espaciais por Lógica Fuzzy Aplicada ao Distrito Ferrífero Nova Aurora, Norte de Minas Gerais

Integração e modelagem de dados geofísicos, geológicos e de sensores remotos, em sistemas de informação geográfica (SIG), têm sido usadas com sucesso em mapeamento geológico e exploração mineral, em todo o mundo, particularmente em áreas com escassos afloramentos rochosos e extensas coberturas cenozoicas. Situado no norte de Minas Gerais, o Distrito Ferrífero Nova Aurora engloba metadiamictitos do Grupo Macaúbas ricos em ferro, relacionados a uma glaciação global do Criogeniano. O distrito, cujas reservastotais superam vinte bilhões de toneladas de minério de ferro (15-60 %Fe), situa-se numa área de extensas chapadas, largamente cobertas por espessos regolitos e sedimentos cenozoicos, escondendo os depósitos de ferro. Os metadiamictitos ricos em ferro contêm quantidades variáveis de hematita (predominante) e magnetita (concentrada em zonas de cisalhamento) na matriz foliada que também inclui quartzo, muscovita, feldspato, granada, clorita e carbonato, dentre outros minerais. Mapas regionais de favorabilidade, baseados em Lógica Fuzzy, apresentados em artigo anterior publicado pelos autores, indicaram grande número de alvos, alguns delesem prospecção avançada pela Companhia Sul Americana de Metais (SAM). O presente artigo focaliza um desses alvos trabalhados pela SAM, visando testar a aplicação daquela metodologia de integração e modelagem de dados geofísicos-espaciais sobre uma área reduzida. O modelo resultante foi validado: i) pelo mapa geológico de detalhe, elaborado durante o trabalho de prospecção; ii) pela distribuição de afloramentos de minério que coincide com as áreas de maior favorabilidade no modelo e; iii) pelas profundidadescalculadas, por deconvolução de Euler, para as fontes magnéticas que são compatíveis com as espessuras do corpo de minério nas seções geológicas controladas por furos de sonda. Os dados e método utilizados foram eficazes na redução da ambiguidade da informação e o modelo integrado restringe as áreas mais favoráveis à ocorrência do minério de ferro

Contrasting provenance and timing of metamorphism fromparagneisses of the Ara?ua?-Ribeira orogenic system, Brazil : hints for Western Gondwana assembly.

The Ara?ua? orogen and the Ribeira belt make up a complex Neoproterozoic-Cambrian orogenic system, the Ara?ua?-Ribeira orogenic system(AROS) located fromthe eastern to southeastern Brazil. Along the AROS, the Ediacaran Rio Doce magmatic arc represents a geotectonic connection between the Ara?ua? and the Ribeira orogenic domains. Although the nature and evolution of the Rio Doce plutonic rocks is regionally well established, it lacks detailed studies on the paragneisses found along the western and central regions of this magmatic arc. Besides information on the nature and provenance of their sedimentary protoliths, the paragneisses provide data to unravel the palaeogeographic scenario fromthe precursor to arc-related basins. Six samples of Al-rich gneisses covering a large AROS region were selected for electron microprobe (EMP) mineral analyses in order to obtain geothermobarometric data and monazite ages, as well as for Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry (LA-ICP-MS) isotopic analyses on zircon (U-Pb, Lu-Hf) and monazite (U-Pb). The different age spectra fromdetrital zircon grains and contrasting Hf isotopic signatures suggest a complex sedimentary history. Located in thewestern sector of the study region, the samples RC-02 and RC-34, with an 80% age peak of detrital zircon grains from 2158 Ma to 1830 Ma, ?Hf(t) from ?2.2 to ?22.7, and Hf TDM model ages from 3530 Ma to 2440 Ma, suggest sediment sources located in the S?o Francisco craton basement. The samples RC-03, also fromthewestern sector, and RC-46 fromthe southern sector, have a more complex assemblage of detrital zircon grains with an 87% age peak from 987 Ma to 592 Ma, ?Hf(t) from +14.9 to ?2.9, and Hf TDM model ages from 2220Ma to 720 Ma, indicating provenance from mainly juvenile sources of distinct ages. Candidates to be juvenile sources for RC-03 and RC-46 sedimentary protoliths are the Rhyacian Juiz de Fora and Pocrane complexes in the basement of the Rio Doce arc, the Neoproterozoic Rio Negro arc systemof the Ribeira belt, and AROS ophiolite complexes. Samples RC-30 and RC-38 from the eastern sector of the study region, with most detrital zircon ages between 650 Ma and 552 Ma and very negative ?Hf(t) (?25.3 to ?16.5), suggest main sediment sources in the Rio Doce arc. By extending U-Pb analyses on metamorphic zircon and monazite, we have identified a complex timing of metamorphism, represented by metamorphic ages ranging from 621 Ma to 480 Ma, with the main collisional activity between 580Ma and 540 Ma. Geothermobarometric studies on garnet porphyroblasts, syn-kinematic to the D2 regional foliation, show a retrograde metamorphic path typical of continental collision belts, starting with P-T conditions of Tmax = 733 ?C and Pmax = 6.43 kbar. Our data also suggest: i) the studied paragneisses represent distinct Neoproterozoic basin stages, shifting from passive to active margin settings; ii) if the Rio Negro arc system really provided sediments for the basin stage represented by the RC-03 and RC-46 paragneisses, it would have amalgamated with the AROS before 614 Ma; iii) the final amalgamation of Western Gondwana took place around 540 Ma in the focused region; iv) an important re-heating period (520?480 Ma) can be related to the AROS gravitational collapse, afterWestern Gondwana assembly

Granites of the intracontinental termination of a magmatic arc : an example from the Ediacaran Ara?ua? orogen, southeastern Brazil.

The Ara?ua? orogen of southeastern Brazil together with the West Congo belt of central West Africa form the Ara?ua??West Congo orogen generated during closure of a terminal segment of the Neoproterozoic Adamastor Ocean. Corresponding to an embayment in the S?o Francisco?Congo Craton, this portion of the Adamastor was only partially floored by oceanic crust. The convergence of its margins led to the development of the Rio Doce magmatic arc between 630 Ma and 580 Ma. The Rio Doce magmatic arc terminates in the northern portion of the Ara?ua? orogen. Granitic plutons exposed in the northern extremity of the arc provide a rare opportunity to studymagmatismat arc terminations, and to understand the interplay between calc-alkalinemagma production and crustal recycling. The plutons forming the terminus of the arc consist of granodiorites, tonalites and monzogranites similar to a magnesian, slightly peraluminous, calcic- (68%) to calc-alkaline (24%), with minor alkali-calcic (8%) facies, medium- to high-K magmatic series. Although marked by negative Nb?Ta, Sr and Ti anomalies, typically associatedwith subduction-relatedmagmas, the combined Sr, Nd and Hf isotopic data characterize a crustal signature related to anatexis of metamorphosed igneous and sedimentary rocks, rather than fractional crystallization of mantle-derived magmas. Zircon U?Pb ages characterizes two groups of granitoids. The older group, crystallized between 630 and 590 Ma, experienced a migmatization event at ca. 585 Ma. The younger granitoids, emplaced between 570 and 590 Ma, do not show any evidence for migmatization. Most of the investigated samples show good correlation with the experimental compositional field of amphibolite dehydration-melting, with some samples plotting into the field of greywacke dehydration-melting. The studied rocks are not typical I-type or S-type granites, being particularly similar to transitional I/S-type granitoids described in the Ordovician Famatinian arc (NW Argentina). We suggest a hybrid model involving dehydrationmelting of meta-igneous (amphibolites) and metasedimentary (greywackes) rocks for magma production in the northern termination of the Rio Doce arc. The real contribution of each end-member is, however, a challenging work still to be done

Digestibilidade de ingredientes em dietas para juvenis de pacamã (Lophiosilurus alexandri)

The objective of this work was to determine the apparent digestibility coefficient (ADC) of six ingredients, in practical and purified reference diets, and to assess the influence of these reference diets on the digestibility of the ingredients in pacman catfish juveniles. The following ingredients were evaluated: fish meal, meat and bone meal, soybean meal, roasted whole soybean, wheat meal, and corn protenose. There was interaction between the reference diet and the studied ingredients. The purified diet provided higher ADC for crude protein and gross energy. Pacman catfish showed high ADC for protein ingredients of vegetable origin for the two reference diets.O objetivo deste trabalho foi determinar o coeficiente de digestibilidade aparente (CDA) de seis ingredientes, em dietas‑referência prática e purificada, e determinar a influência das dietas‑referência sobre a digestibilidade dos ingredientes em juvenis de pacamã. Avaliaram-se os seguintes ingredientes: farinha de peixe, farinha de carne e ossos, farelo de soja, soja integral tostada, farelo de trigo e protenose de milho. Houve interação entre a dieta‑referência e os ingredientes estudados. A dieta purificada proporcionou maior CDA quanto à proteína bruta e energia bruta. O pacamã apresentou CDAs elevados quanto aos ingredientes proteicos de origem vegetal, nas duas dietas‑referência.

Determinants of intensive insulin therapeutic regimens in patients with type 1 diabetes: data from a nationwide multicenter survey in Brazil

Background: To evaluate the determinants of intensive insulin regimens (ITs) in patients with type 1 diabetes (T1D).Methods: This multicenter study was conducted between December 2008 and December 2010 in 28 public clinics in 20 Brazilian cities. Data were obtained from 3,591 patients (56.0% female, 57.1% Caucasian). Insulin regimens were classified as follows: group 1, conventional therapy (CT) (intermediate human insulin, one to two injections daily); group 2 (three or more insulin injections of intermediate plus regular human insulin); group 3 (three or more insulin injections of intermediate human insulin plus short-acting insulin analogues); group 4, basal-bolus (one or two insulin injections of long-acting plus short-acting insulin analogues or regular insulin); and group 5, basal-bolus with continuous subcutaneous insulin infusion (CSII). Groups 2 to 5 were considered IT groups.Results: We obtained complete data from 2,961 patients. Combined intermediate plus regular human insulin was the most used therapeutic regimen. CSII was used by 37 (1.2%) patients and IT by 2,669 (90.2%) patients. More patients on IT performed self-monitoring of blood glucose and were treated at the tertiary care level compared to CT patients (p < 0.001). the majority of patients from all groups had HbA1c levels above the target. Overweight or obesity was not associated with insulin regimen. Logistic regression analysis showed that economic status, age, ethnicity, and level of care were associated with IT (p < 0.001).Conclusions: Given the prevalence of intensive treatment for T1D in Brazil, more effective therapeutic strategies are needed for long term-health benefits.Farmanguinhos/Fundacao Oswaldo Cruz/National Health MinistryBrazilian Diabetes SocietyFundacao do Amparo a Pesquisa do Estado do Rio de JaneiroConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Univ Estado Rio de Janeiro, Unit Diabet, BR-20551030 Rio de Janeiro, BrazilBaurus Diabet Assoc, São Paulo, BrazilFed Univ São Paulo State, Diabet Unit, São Paulo, BrazilFed Univ Hosp Porto Alegre, Porto Alegre, BrazilUniv Hosp São Paulo, Diabet Unit, São Paulo, BrazilUniv Fed Rio de Janeiro, Rio de Janeiro, BrazilUniv Fed Ceara, Fortaleza, Ceara, BrazilSanta Casa Misericordia, Belo Horizonte, MG, BrazilSanta Casa Misericordia São Paulo, São Paulo, BrazilUniv Fed Amazonas, Manaus, Amazonas, BrazilHosp Geral de Bonsucesso, Rio de Janeiro, BrazilHosp Univ Clementino Fraga Filho IPPMG, Rio de Janeiro, BrazilUniv Hosp São Paulo, São Paulo, BrazilFac Ciencias Med Santa Casa São Paulo, São Paulo, BrazilUniv São Paulo, Inst Crianca, Hosp Clin, São Paulo, BrazilUniv São Paulo, Fac Med Ribeirao Preto, Hosp Clin, Ribeirao Preto, BrazilAmbulatorio Fac Estadual Med Sao Jose Rio Preto, Ribeirao Preto, BrazilEscola Paulista Med, Ctr Diabet, Ribeirao Preto, BrazilClin Endocrinol Santa Casa Belo Horizonte, Belo Horizonte, MG, BrazilUniv Estadual Londrina, Londrina, BrazilUniv Fed Parana, Hosp Clin, Porto Alegre, RS, BrazilInst Crianca Com Diabet Rio Grande Sul, Rio Grande Do Sul, RS, BrazilGrp Hosp Conceicao, Inst Crianca Com Diabet, Porto Alegre, RS, BrazilHosp Univ Santa Catarina, Florianopolis, SC, BrazilInst Diabet Endocrinol Joinville, Joinville, BrazilHosp Reg Taguatinga, Brasilia, DF, BrazilHosp Geral Goiania, Goiania, Go, BrazilCtr Diabet & Endocrinol Estado Bahia, Goiania, Go, BrazilUniv Fed Maranhao, Sao Luis, BrazilCtr Integrado Diabet & Hipertensao Ceara, Fortaleza, Ceara, BrazilUniv Fed Sergipe, Aracaju, BrazilHosp Univ Alcides Carneiro, Campina Grande, BrazilHosp Univ Joao de Barros Barreto, Belem, Para, BrazilFed Univ São Paulo State, Diabet Unit, São Paulo, BrazilUniv Hosp São Paulo, Diabet Unit, São Paulo, BrazilUniv Hosp São Paulo, São Paulo, BrazilEscola Paulista Med, Ctr Diabet, Ribeirao Preto, BrazilWeb of Scienc

Health-related quality of life in patients with type 1 diabetes mellitus in the different geographical regions of Brazil : data from the Brazilian Type 1 Diabetes Study Group

Background: In type 1 diabetes mellitus (T1DM) management, enhancing health-related quality of life (HRQoL) is as important as good metabolic control and prevention of secondary complications. This study aims to evaluate possible regional differences in HRQoL, demographic features and clinical characteristics of patients with T1DM in Brazil, a country of continental proportions, as well as investigate which variables could influence the HRQoL of these individuals and contribute to these regional disparities. Methods: This was a retrospective, cross-sectional, multicenter study performed by the Brazilian Type 1 Diabetes Study Group (BrazDiab1SG), by analyzing EuroQol scores from 3005 participants with T1DM, in 28 public clinics, among all geographical regions of Brazil. Data on demography, economic status, chronic complications, glycemic control and lipid profile were also collected. Results: We have found that the North-Northeast region presents a higher index in the assessment of the overall health status (EQ-VAS) compared to the Southeast (74.6 ± 30 and 70.4 ± 19, respectively; p < 0.05). In addition, North- Northeast presented a lower frequency of self-reported anxiety-depression compared to all regions of the country (North-Northeast: 1.53 ± 0.6; Southeast: 1.65 ± 0.7; South: 1.72 ± 0.7; Midwest: 1.67 ± 0.7; p < 0.05). These findings could not be entirely explained by the HbA1c levels or the other variables examined. Conclusions: Our study points to the existence of additional factors not yet evaluated that could be determinant in the HRQoL of people with T1DM and contribute to these regional disparities

Diretrizes Brasileiras de Medidas da Pressão Arterial Dentro e Fora do Consultório – 2023

Hypertension is one of the primary modifiable risk factors for morbidity and mortality worldwide, being a major risk factor for coronary artery disease, stroke, and kidney failure. Furthermore, it is highly prevalent, affecting more than one-third of the global population. Blood pressure measurement is a MANDATORY procedure in any medical care setting and is carried out by various healthcare professionals. However, it is still commonly performed without the necessary technical care. Since the diagnosis relies on blood pressure measurement, it is clear how important it is to handle the techniques, methods, and equipment used in its execution with care. It should be emphasized that once the diagnosis is made, all short-term, medium-term, and long-term investigations and treatments are based on the results of blood pressure measurement. Therefore, improper techniques and/or equipment can lead to incorrect diagnoses, either underestimating or overestimating values, resulting in inappropriate actions and significant health and economic losses for individuals and nations. Once the correct diagnosis is made, as knowledge of the importance of proper treatment advances, with the adoption of more detailed normal values and careful treatment objectives towards achieving stricter blood pressure goals, the importance of precision in blood pressure measurement is also reinforced. Blood pressure measurement (described below) is usually performed using the traditional method, the so-called casual or office measurement. Over time, alternatives have been added to it, through the use of semi-automatic or automatic devices by the patients themselves, in waiting rooms or outside the office, in their own homes, or in public spaces. A step further was taken with the use of semi-automatic devices equipped with memory that allow sequential measurements outside the office (ABPM; or HBPM) and other automatic devices that allow programmed measurements over longer periods (HBPM). Some aspects of blood pressure measurement can interfere with obtaining reliable results and, consequently, cause harm in decision-making. These include the importance of using average values, the variation in blood pressure during the day, and short-term variability. These aspects have encouraged the performance of a greater number of measurements in various situations, and different guidelines have advocated the use of equipment that promotes these actions. Devices that perform HBPM or ABPM, which, in addition to allowing greater precision, when used together, detect white coat hypertension (WCH), masked hypertension (MH), sleep blood pressure alterations, and resistant hypertension (RHT) (defined in Chapter 2 of this guideline), are gaining more and more importance. Taking these details into account, we must emphasize that information related to diagnosis, classification, and goal setting is still based on office blood pressure measurement, and for this reason, all attention must be given to the proper execution of this procedure.La hipertensión arterial (HTA) es uno de los principales factores de riesgo modificables para la morbilidad y mortalidad en todo el mundo, siendo uno de los mayores factores de riesgo para la enfermedad de las arterias coronarias, el accidente cerebrovascular (ACV) y la insuficiencia renal. Además, es altamente prevalente y afecta a más de un tercio de la población mundial. La medición de la presión arterial (PA) es un procedimiento OBLIGATORIO en cualquier atención médica o realizado por diferentes profesionales de la salud. Sin embargo, todavía se realiza comúnmente sin los cuidados técnicos necesarios. Dado que el diagnóstico se basa en la medición de la PA, es claro el cuidado que debe haber con las técnicas, los métodos y los equipos utilizados en su realización. Debemos enfatizar que una vez realizado el diagnóstico, todas las investigaciones y tratamientos a corto, mediano y largo plazo se basan en los resultados de la medición de la PA. Por lo tanto, las técnicas y/o equipos inadecuados pueden llevar a diagnósticos incorrectos, subestimando o sobreestimando valores y resultando en conductas inadecuadas y pérdidas significativas para la salud y la economía de las personas y las naciones. Una vez realizado el diagnóstico correcto, a medida que avanza el conocimiento sobre la importancia del tratamiento adecuado, con la adopción de valores de normalidad más detallados y objetivos de tratamiento más cuidadosos hacia metas de PA más estrictas, también se refuerza la importancia de la precisión en la medición de la PA. La medición de la PA (descrita a continuación) generalmente se realiza mediante el método tradicional, la llamada medición casual o de consultorio. Con el tiempo, se han agregado alternativas a través del uso de dispositivos semiautomáticos o automáticos por parte del propio paciente, en salas de espera o fuera del consultorio, en su propia residencia o en espacios públicos. Se dio un paso más con el uso de dispositivos semiautomáticos equipados con memoria que permiten mediciones secuenciales fuera del consultorio (AMPA; o MRPA) y otros automáticos que permiten mediciones programadas durante períodos más largos (MAPA). Algunos aspectos en la medición de la PA pueden interferir en la obtención de resultados confiables y, en consecuencia, causar daños en las decisiones a tomar. Estos incluyen la importancia de usar valores promedio, la variación de la PA durante el día y la variabilidad a corto plazo. Estos aspectos han alentado la realización de un mayor número de mediciones en diversas situaciones, y diferentes pautas han abogado por el uso de equipos que promuevan estas acciones. Los dispositivos que realizan MRPA o MAPA, que además de permitir una mayor precisión, cuando se usan juntos, detectan la hipertensión de bata blanca (HBB), la hipertensión enmascarada (HM), las alteraciones de la PA durante el sueño y la hipertensión resistente (HR) (definida en el Capítulo 2 de esta guía), están ganando cada vez más importancia. Teniendo en cuenta estos detalles, debemos enfatizar que la información relacionada con el diagnóstico, la clasificación y el establecimiento de objetivos todavía se basa en la medición de la presión arterial en el consultorio, y por esta razón, se debe prestar toda la atención a la ejecución adecuada de este procedimiento.A hipertensão arterial (HA) é um dos principais fatores de risco modificáveis para morbidade e mortalidade em todo o mundo, sendo um dos maiores fatores de risco para doença arterial coronária, acidente vascular cerebral (AVC) e insuficiência renal. Além disso, é altamente prevalente e atinge mais de um terço da população mundial. A medida da PA é procedimento OBRIGATÓRIO em qualquer atendimento médico ou realizado por diferentes profissionais de saúde. Contudo, ainda é comumente realizada sem os cuidados técnicos necessários. Como o diagnóstico se baseia na medida da PA, fica claro o cuidado que deve haver com as técnicas, os métodos e os equipamentos utilizados na sua realização. Deve-se reforçar que, feito o diagnóstico, toda a investigação e os tratamentos de curto, médio e longo prazos são feitos com base nos resultados da medida da PA. Assim, técnicas e/ou equipamentos inadequados podem levar a diagnósticos incorretos, tanto subestimando quanto superestimando valores e levando a condutas inadequadas e grandes prejuízos à saúde e à economia das pessoas e das nações. Uma vez feito o diagnóstico correto, na medida em que avança o conhecimento da importância do tratamento adequado, com a adoção de valores de normalidade mais detalhados e com objetivos de tratamento mais cuidadosos no sentido do alcance de metas de PA mais rigorosas, fica também reforçada a importância da precisão na medida da PA. A medida da PA (descrita a seguir) é habitualmente feita pelo método tradicional, a assim chamada medida casual ou de consultório. Ao longo do tempo, foram agregadas alternativas a ela, mediante o uso de equipamentos semiautomáticos ou automáticos pelo próprio paciente, nas salas de espera ou fora do consultório, em sua própria residência ou em espaços públicos. Um passo adiante foi dado com o uso de equipamentos semiautomáticos providos de memória que permitem medidas sequenciais fora do consultório (AMPA; ou MRPA) e outros automáticos que permitem medidas programadas por períodos mais prolongados (MAPA). Alguns aspectos na medida da PA podem interferir na obtenção de resultados fidedignos e, consequentemente, causar prejuízo nas condutas a serem tomadas. Entre eles, estão: a importância de serem utilizados valores médios, a variação da PA durante o dia e a variabilidade a curto prazo. Esses aspectos têm estimulado a realização de maior número de medidas em diversas situações, e as diferentes diretrizes têm preconizado o uso de equipamentos que favoreçam essas ações. Ganham cada vez mais espaço os equipamentos que realizam MRPA ou MAPA, que, além de permitirem maior precisão, se empregados em conjunto, detectam a HA do avental branco (HAB), HA mascarada (HM), alterações da PA no sono e HA resistente (HAR) (definidos no Capítulo 2 desta diretriz). Resguardados esses detalhes, devemos ressaltar que as informações relacionadas a diagnóstico, classificação e estabelecimento de metas ainda são baseadas na medida da PA de consultório e, por esse motivo, toda a atenção deve ser dada à realização desse procedimento

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio