12 research outputs found

    Andreev reflection at QGP/CFL interface

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    In this letter we address the question of the phenomena of Andreev reflection between the cold quark-gluon plasma phase and CFL color superconductor. We show that there are two different types of reflections connected to the structure of the CFL phase. We also calculate the probability current at the interface and we show that it vanishes for energy of scattering quarks below the superconducting gap.Comment: 6 pages, 1 figure. Minor changes in the "Conclusions

    Rac1 acts in conjunction with Nedd4 and dishevelled-1 to promote maturation of cell-cell contacts

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    The Rho-GTPase Rac1 promotes actin polymerization and membrane protrusion that mediate initial contact and subsequent maturation of cell-cell junctions. Here we report that Rac1 associates with the ubiquitin-protein ligase neural precursor cell expressed developmentally down-regulated 4 (Nedd4). This interaction requires the hypervariable C-terminal domain of Rac1 and the WW domains of Nedd4. Activated Rac1 colocalises with endogenous Nedd4 at epithelial cell-cell contacts. Reduction of Nedd4 expression by shRNA results in reduced transepithelial electrical resistance (TER) and concomitant changes in the distribution of adherens and tight junction markers. Conversely, expression of Nedd4 promotes TER, suggesting that Nedd4 cooperates with Rac1 in the induction of junctional maturation. We found that Nedd4, but not Nedd4-2, mediates the ubiquitylation and degradation of the adapter protein dishevelled-1 (Dvl1), the expression of which negatively regulates cell-cell contact. Nedd4-mediated ubiquitylation requires its binding to the C-terminal domain of Dvl1, comprising the DEP domain, and targets an N-terminal lysine-rich region upstream of the Dvl1 DIX domain. We found that endogenous Rac1 colocalises with endogenous Dvl1 in intracellular puncta as well as on cell-cell junctions. Finally, activated Rac1 was found to stimulate Nedd4 activity, resulting in increased ubiquitylation of Dvl1. Together, these data reveal a novel Rac1-dependent signalling pathway that, through Nedd4-mediated ubiquitylation of Dvl1, stimulates the maturation of epithelial cell-cell contacts

    Observation of WWWWWW Production in pppp Collisions at s\sqrt s =13  TeV with the ATLAS Detector

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    International audienceThis Letter reports the observation of WWWWWW production and a measurement of its cross section using 139 fb1^{-1} of proton-proton collision data recorded at a center-of-mass energy of 13 TeV by the ATLAS detector at the Large Hadron Collider. Events with two same-sign leptons (electrons or muons) and at least two jets, as well as events with three charged leptons, are selected. A multivariate technique is then used to discriminate between signal and background events. Events from WWWWWW production are observed with a significance of 8.0 standard deviations, where the expectation is 5.4 standard deviations. The inclusive WWWWWW production cross section is measured to be 820±100(stat)±80(syst)820 \pm 100\,\text{(stat)} \pm 80\,\text{(syst)} fb, approximately 2.6 standard deviations from the predicted cross section of 511±18511 \pm 18 fb calculated at next-to-leading-order QCD and leading-order electroweak accuracy

    Observation of WWWWWW Production in pppp Collisions at s\sqrt s =13  TeV with the ATLAS Detector

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    International audienceThis Letter reports the observation of WWWWWW production and a measurement of its cross section using 139 fb1^{-1} of proton-proton collision data recorded at a center-of-mass energy of 13 TeV by the ATLAS detector at the Large Hadron Collider. Events with two same-sign leptons (electrons or muons) and at least two jets, as well as events with three charged leptons, are selected. A multivariate technique is then used to discriminate between signal and background events. Events from WWWWWW production are observed with a significance of 8.0 standard deviations, where the expectation is 5.4 standard deviations. The inclusive WWWWWW production cross section is measured to be 820±100(stat)±80(syst)820 \pm 100\,\text{(stat)} \pm 80\,\text{(syst)} fb, approximately 2.6 standard deviations from the predicted cross section of 511±18511 \pm 18 fb calculated at next-to-leading-order QCD and leading-order electroweak accuracy

    Observation of WWWWWW Production in pppp Collisions at s\sqrt s =13  TeV with the ATLAS Detector

    No full text
    International audienceThis Letter reports the observation of WWWWWW production and a measurement of its cross section using 139 fb1^{-1} of proton-proton collision data recorded at a center-of-mass energy of 13 TeV by the ATLAS detector at the Large Hadron Collider. Events with two same-sign leptons (electrons or muons) and at least two jets, as well as events with three charged leptons, are selected. A multivariate technique is then used to discriminate between signal and background events. Events from WWWWWW production are observed with a significance of 8.0 standard deviations, where the expectation is 5.4 standard deviations. The inclusive WWWWWW production cross section is measured to be 820±100(stat)±80(syst)820 \pm 100\,\text{(stat)} \pm 80\,\text{(syst)} fb, approximately 2.6 standard deviations from the predicted cross section of 511±18511 \pm 18 fb calculated at next-to-leading-order QCD and leading-order electroweak accuracy

    Observation of WWWWWW Production in pppp Collisions at s\sqrt s =13  TeV with the ATLAS Detector

    No full text
    International audienceThis Letter reports the observation of WWWWWW production and a measurement of its cross section using 139 fb1^{-1} of proton-proton collision data recorded at a center-of-mass energy of 13 TeV by the ATLAS detector at the Large Hadron Collider. Events with two same-sign leptons (electrons or muons) and at least two jets, as well as events with three charged leptons, are selected. A multivariate technique is then used to discriminate between signal and background events. Events from WWWWWW production are observed with a significance of 8.0 standard deviations, where the expectation is 5.4 standard deviations. The inclusive WWWWWW production cross section is measured to be 820±100(stat)±80(syst)820 \pm 100\,\text{(stat)} \pm 80\,\text{(syst)} fb, approximately 2.6 standard deviations from the predicted cross section of 511±18511 \pm 18 fb calculated at next-to-leading-order QCD and leading-order electroweak accuracy

    Observation of WWWWWW Production in pppp Collisions at s\sqrt s =13  TeV with the ATLAS Detector

    No full text
    International audienceThis Letter reports the observation of WWWWWW production and a measurement of its cross section using 139 fb1^{-1} of proton-proton collision data recorded at a center-of-mass energy of 13 TeV by the ATLAS detector at the Large Hadron Collider. Events with two same-sign leptons (electrons or muons) and at least two jets, as well as events with three charged leptons, are selected. A multivariate technique is then used to discriminate between signal and background events. Events from WWWWWW production are observed with a significance of 8.0 standard deviations, where the expectation is 5.4 standard deviations. The inclusive WWWWWW production cross section is measured to be 820±100(stat)±80(syst)820 \pm 100\,\text{(stat)} \pm 80\,\text{(syst)} fb, approximately 2.6 standard deviations from the predicted cross section of 511±18511 \pm 18 fb calculated at next-to-leading-order QCD and leading-order electroweak accuracy

    Observation of WWWWWW Production in pppp Collisions at s\sqrt s =13  TeV with the ATLAS Detector

    No full text
    International audienceThis Letter reports the observation of WWWWWW production and a measurement of its cross section using 139 fb1^{-1} of proton-proton collision data recorded at a center-of-mass energy of 13 TeV by the ATLAS detector at the Large Hadron Collider. Events with two same-sign leptons (electrons or muons) and at least two jets, as well as events with three charged leptons, are selected. A multivariate technique is then used to discriminate between signal and background events. Events from WWWWWW production are observed with a significance of 8.0 standard deviations, where the expectation is 5.4 standard deviations. The inclusive WWWWWW production cross section is measured to be 820±100(stat)±80(syst)820 \pm 100\,\text{(stat)} \pm 80\,\text{(syst)} fb, approximately 2.6 standard deviations from the predicted cross section of 511±18511 \pm 18 fb calculated at next-to-leading-order QCD and leading-order electroweak accuracy

    Observation of WWW Production in pp Collisions at p=13 TeV with the ATLAS Detector ffi s

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    This Letter reports the observation of WWW production and a measurement of its cross section using 139  fb^{-1} of proton-proton collision data recorded at a center-of-mass energy of 13 TeV by the ATLAS detector at the Large Hadron Collider. Events with two same-sign leptons (electrons or muons) and at least two jets, as well as events with three charged leptons, are selected. A multivariate technique is then used to discriminate between signal and background events. Events from WWW production are observed with a significance of 8.0 standard deviations, where the expectation is 5.4 standard deviations. The inclusive WWW production cross section is measured to be 820±100 (stat)±80 (syst)  fb, approximately 2.6 standard deviations from the predicted cross section of 511±18  fb calculated at next-to-leading-order QCD and leading-order electroweak accuracy
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