Is There a Better Way? Applying Rules of Science to the Process of Improving Schools

Models of school reform centered around high stakes tests for students and schools are sweeping across the educational landscape of America

Mrub_1867, Mrub_1868, and Mrub_1869 genes are predicted orthologs of the b2279, b2280, and b2281 genes found in \u3cem\u3eEscherichia coli\u3c/em\u3e coding for the NADH dehydrogenase subunits K, J, and I respectively

This project is part of the Meiothermus ruber genome analysis project, which uses the bioinformatics tools associated with the Guiding Education through Novel Investigation –Annotation Collaboration Toolkit (GENI-ACT) to predict gene function. We investigated the biological function of the genes Mrub_1867, Mrub_1868, and Mrub_1869. We predict that Mrub_1867 (DNA coordinates 1927237..1927527 on the reverse strand), Mrub_1868 (DNA coordinates 1927524..1928123 on the reverse strand), and Mrub_1869 (DNA coordinates 1928248..1928781 on the reverse strand) are subunits of the NADH: ubiquinone oxidoreductase complex (KEGG map number 00190). This complex catalyzes the translocation of H+ across the cytoplasmic membrane and transfers electrons from NADH to ubiquinone during oxidative phosphorylation. The respective E. coli K12 MG1655 orthologs are predicted to be b2279, b2280, and b2281 which have the gene identifiers NuoK, NuoJ, and NuoI

Process for the Production of Star Tracklng [Tracking] Reticles

A method for the production of reticles, particularly those for use in outer space, wherein the product is a quartz base coated with highly adherent layers of chromium, chromium-silver, and silver vacuum deposited through a mask, and then coated with an electrodeposit of copper from a copper sulfate solution followed by an electrodeposit of black chromium. The masks are produced by coating a beryllium-copper alloy substrate with a positive working photoresist, developing the photoresist according to a pattern to leave a positive mask, plating uncoated areas with gold, removing the photoresist, coating the substrate with a negative working photoresist, developing the negative working photoresist to expose the base metal of the pattern, and chemically etching the unplated side of the pattern to produce the mask. The mask produced is then used in the vacuum deposition of: (1) chromium metal on the surface of a quartz base to obtain a highly adherent quartz-chromium interface; (2) silver on the chromium deposit, during the final stage of chromium deposit, to produce a silver chromium alloy layer; and (3) silver onto the surface of the alloy layer. The coated quartz base is then coated by electroplating utilizing an acid copper deposit followed by a black chromium electrodeposit to produce the product of the present invention

Peroxisome Proliferator-Activated Receptors: “Key” Regulators of Neuroinflammation after Traumatic Brain Injury

Traumatic brain injury is characterized by neuroinflammatory pathological sequelae which contribute to brain edema and delayed neuronal cell death. Until present, no specific pharmacological compound has been found, which attenuates these pathophysiological events and improves the outcome after head injury. Recent experimental studies suggest that targeting peroxisome proliferator-activated receptors (PPARs) may represent a new anti-inflammatory therapeutic concept for traumatic brain injury. PPARs are “key” transcription factors which inhibit NFκB activity and downstream transcription products, such as proinflammatory and proapoptotic cytokines. The present review outlines our current understanding of PPAR-mediated neuroprotective mechanisms in the injured brain and discusses potential future anti-inflammatory strategies for head-injured patients, with an emphasis on the putative beneficial combination therapy of synthetic cannabinoids (e.g., dexanabinol) with PPARα agonists (e.g., fenofibrate)

Congenital pseudarthrosis of the tibia : treatment with free vascularised fibular grafts

CITATION: Smith, C. S. F., Zeeman, V. R. B. J. & Wade, W. J. 1993. Congenital pseudarthrosis of the tibia : treatment with free vascularised fibular grafts. South African Medical Journal, 83:750-752.The original publication is available at http://www.samj.org.zaCongenital pseudarthrosis is uncommon. We report on a series of 4 patients treated by means of free vascularised fibular grafts. Complications encountered were graft fracture, delayed union and angulation deformities. Modifications in the surgical technique improved later results. We recommend wide excision of pathological bone, bridging of the defect by free vascularised fibular grafts and rigid fixation.Publisher’s versio

Modeling black student academic performance in higher education

Recent research has noted differences in the predictive efficacy of educational attainment models produced for whites as opposed to blacks; and called for more resolution in the findings on blacks in advance of further comparative analyses. The National Study of Black College Students (NSBCS) is employed to develop a model that distinguishes between high- and low-performing black undergraduates attending public, four-year institutions. In the NSBCS sample ( N =695), discriminant function analysis identifies several institutional and student characteristics which are related to black students' educational outcomes. Specifically, students with both high occupational aspirations and high academic performances tend to be male, attend comparatively larger schools, and, to a lesser degree, be relatively well-adjusted upperclassmen. When academic performance is the sole issue, it is positively correlated with institutional quality, but the advantage belongs to black females. Contrary to the suggestions of previous research, black community sentiment did not have relationships with educational outcomes to the extent expected. These results suggest that future models of black educational attainment marry traditional Wisconsin-type measures with institutional and student attributes.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/43592/1/11162_2004_Article_BF00975106.pd

Modeling Storm Surge and Inundation in Washington, DC, during Hurricane Isabel and the 1936 Potomac River Great Flood

Abstract: Washington, DC, the capital of the U.S., is located along the Upper Tidal Potomac River, where a reliable operational model is needed for making predictions of storm surge and river-induced flooding. We set up a finite volume model using a semi-implicit, Eulerian-Lagrangian scheme on a base grid (200 m) and a special feature of sub-grids (10 m), sourced with high-resolution LiDAR data and bathymetry surveys. The model domain starts at the fall line and extends 120 km downstream to Colonial Beach, VA. The model was used to simulate storm tides during the 2003 Hurricane Isabel. The water level measuring 3.1 m reached the upper tidal river in the vicinity of Washington during the peak of the storm, followed by second and third flood peaks two and four days later, resulting from river flooding coming downstream after heavy precipitation in the watershed. The modeled water level and timing were accurate in matching with the verified peak observations within 9 cm and 3 cm, and with R2 equal to 0.93 and 0.98 at the Wisconsin Avenue and Washington gauges, respectively. A simulation was also conducted for reconstructing the historical 1936 Potomac River Great Flood that inundated downtown. It was identified that the flood water, with a velocity exceeding 2.7 m/s in the downstream of Roosevelt Island, pinched through the bank northwest of East Potomac Park near DC. The modeled maximum inundation extents revealed a crescent-shaped flooding area, which was consistent with the historical surveyed flood map of the event

Blunt injury to the inferior gluteal artery: case report of a rare "near miss" event

Traumatic injuries of the inferior gluteal artery are rare, the majority of which are aneurysms due to sharp or blunt trauma. We report the rare case of a "near miss" event of a patient with an acute hemorrhagic mass in the right buttock caused by blunt trauma to the inferior gluteal artery without "hard" clinical signs of vascular injury. Despite the unusual presentation, diffuse injury of the inferior gluteal artery branches was diagnosed by ultrasonography and angiography. This article highlights the importance of considering an arterial injury following blunt trauma to the buttock with subsequent pain and swelling. Appreciation of this rare injury pattern is necessary in order to facilitate rapid diagnosis and appropriate treatment

Severe postpartum disruption of the pelvic ring: report of two cases and review of the literature

Pelvic dislocations are rare during labor, and the treatment is controversial. We report two cases of young women who sustained postpartum disruption of the pelvic ring: one case is an 8.8 cm wide separation of the pubic symphysis with sacroiliac joint disruption underwent surgical stabilization and the second case with 4.0 cm disruption being treated non-operatively. These cases illustrated of importance of accurate diagnosis, careful physical exam, fully informed consent and specific treatment for this condition