Field Excavation Report Season 1: 2018 Summer Field School Millard’s Farmstead 41NA416 Permit #8424

In the summer of 2018 (June 4-July6), SFA Archaeological Field School (ANT440) was lead by Dr. Leslie G. Cecil and Laura Short (adjunct professor at the time) and had 10 students and one volunteer. The site selected was the Millard’s Farmstead located behind the Nacogdoches ISD Agricultural Center on the Northwest Loop in Nacogdoches, TX. The site is approximately 1.62 acres in area of which only 28 m2 were excavated. Alton Frailey (the NISD superintendent at the time) approved the excavation of the site for multiple field seasons. The site currently sits on NISD property. A pedestrian survey in April 2018 located the farmstead’s fireplace and excavations were conducted around it to best determine the placement of the house. The house had been razed during the 1970s; however, the crib barn still stood. At the end of the field season, representatives moved the crib barn to Millard’s Crossing under George Avery’s supervisions. A total of 9026 artifacts were recovered and are curated at the SFA Anthropology and Archaeology Laboratory. Future research at the site will continue once COVID-19 is no longer an issue in order to capture other information about this time period in Nacogdoches history

Uspon ambasadora robne marke: društveni udio, korporativna društvena odgovornost i utjecaj među utjecajnim osobama na društvenim mrežama

One of social media’s influences on public relations has been the connection they provide organizations with stakeholder groups, and the need to recognize new and emerging stakeholder groups and their influence on the organization. One such stakeholder group with social media-borne influence and recognition in public relations is brand ambassadors, who distribute organizational content to social networks. This study examines the meanings and motivations of brand ambassadors in establishing relationships with an organization, and their considerations in representing and distributing content for an organization. In particular, we examined the consideration of corporate social responsibility (CSR) content among brand ambassadors. Findings suggest complex considerations of loyalties, commitments, and stakes within the brand ambassador-organization relationship. CSR content’s value among ambassadors was questionable. The ethical issues of organizational ties, including compensation, are discussed.Jedan od utjecaja društvenih medija na odnose s javnošću bila je veza koju osiguravaju organizacijama sa skupinama dionika te potreba za prepoznavanjem novih i novonastalih skupina dionika i njihovog utjecaja na organizaciju. Jedna takva skupina dionika s utjecajem na društvenim mrežama i prepoznatljivošću u odnosima s javnošću su ambasadori robnih marki, koji distribuiraju organizacijski sadržaj društvenim mrežama. Ova studija ispituje značenja i motivaciju ambasadora robne marke u uspostavljanju odnosa s organizacijom te njihova razmatranja u predstavljanju i distribuciji sadržaja za organizaciju. Konkretno, ispitali smo razmatranje sadržaja o društveno odgovornom poslovanju (CSR) među ambasadorima brendova. Nalazi upućuju na složena razmatranja lojalnosti, obveza i udjela unutar odnosa ambasadora marke i organizacije. Vrijednost sadržaja DOP-a među veleposlanicima bila je upitna. Razmatraju se etička pitanja organizacijskih veza, uključujući naknade

Playing to Live: Outcome Evaluation of a Community-Based Psychosocial Expressive Arts Program for Children During the Liberian Ebola Epidemic

Background. This paper reviews the efficacy of a community psychosocial arts program focused on building mental health capacity within post-Ebola Liberia. The aim of this paper was to evaluate the outcome effects of two groups using pre- and post-treatment data. We hypothesized that there would be a difference in symptoms pre- and post-treatment, and the longer program would yield more significant results. Methods. There was a total of 870 child participants. Of 40 sites, 24 were selected for a 5-month treatment (TG1) while the remaining 16 sites received 3 months of treatment (TG2). Paired t tests and a mixed-model analysis of variance (ANOVA) were used to analyse pre- and post-psychological stress symptoms (PSS) for samples from both groups. Results. Separately, treatment group 1 (TG1) and treatment group 2\u27s (TG2) paired t test yielded significant results (p \u3c 0.001) for the decrease of PSS. The mixed-model ANOVA found that there were significant differences in total pre- and post-test PSS and a significant difference in PSS means over time. Conclusions. Results indicated that there was a statistically significant decrease in reported symptoms in both treatment groups pre- to post-intervention and a significant difference in total symptoms over time. However, the findings do not indicate that the longer programming was statistically different compared to the shorter programming. The study presented had gaps in data, largely due to limits in research during the crisis. However, this paper provides a unique case study for challenges that can be faced for project evaluation in emergency settings

Early Introduction to Professional and Ethical Dilemmas in a Pharmaceutical Care Laboratory Course

Objective. To study the effects of an early professional development series in a pharmaceutical care laboratory (PCL) course on first-year pharmacy students’ perceptions of the importance of professional attitudes and action

Cell non-autonomous regulation of hepatic IGF-1 and neonatal growth by Kinase Suppressor of Ras 2 (KSR2)

Individuals with poor postnatal growth are at risk for cardiovascular and metabolic problems as adults. Here we show that disruption of the molecular scaffold Kinase Suppressor of Ras 2 (KSR2) causes selective inhibition of hepatic GH signaling in neonatal mice with impaired expression of IGF-1 and IGFBP3. ksr2−/− mice are normal size at birth but show a marked increase in FGF21 accompanied by reduced body mass, shortened body length, and reduced bone mineral density (BMD) and content (BMC) first evident during postnatal development. However, disrupting FGF21 in ksr2−/− mice does not normalize mass, length, or bone density and content in fgf21−/−ksr2−/− mice. Body length, BMC and BMD, but not body mass, are rescued by infection of two-day-old ksr2−/− mice with a recombinant adenovirus encoding human IGF-1. Relative to wild-type mice, GH injections reveal a significant reduction in JAK2 and STAT5 phosphorylation in liver, but not in skeletal muscle, of ksr2−/− mice. However, primary hepatocytes isolated from ksr2−/− mice show no reduction in GH-stimulated STAT5 phosphorylation. These data indicate that KSR2 functions in a cell non-autonomous fashion to regulate GH-stimulated IGF-1 expression in the liver of neonatal mice, which plays a key role in the development of body length

Impact of historical gold mining activities on marine sediments in Wine Harbour, Nova Scotia, Canada

Past investigations at historical gold (Au) districts in Nova Scotia, Canada have identified elevated concentrations of arsenic (As) and mercury (Hg) in nearby sediments and waters. These metal(loid)s are derived from erosion of mineralized bedrock, and the disposal of mine tailings into the environment during early operations. The Wine Harbour gold district is located along the eastern shore of Nova Scotia, and produced 1329 kg of Au from 75 581 tonnes of crushed rock from 1862 to 1939.The gold occurs in arsenopyrite-bearing quartz-carbonate veins and was extracted using stamp milling and Hg amalgamation. Historical maps document tailings deposits near former stamp mill sites; however, the extent to which these mine wastes influence environmental quality in the adjacent marine environment is uncertain. In this study, we measured metal(loid) concentrations in tailings, marine sediments, and surface waters to assess the lateral and vertical extent of mining-related impacts on Wine Harbour. Chemical analyses of terrestrial and intertidal tailings reveal high concentrations of both As (86–196 000 mg/kg) and Hg (444–320 000 µg/kg). Analyses of marine sediments show a wide range in both As (4–568 mg/kg) and Hg (<5–7430 µg/kg) concentrations. In general, the highest metal(loid) concentrations in sediments were recorded down-gradient of stamp mill sites. Elevated concentrations were also detected in sediments underlying an active mussel aquaculture operation at the western end of the harbour. Results from this study have been used to help assess potential ecosystem and human health risks associated with historical gold mine wastes in the Wine Harbour area

Reproducibility and a unifying explanation: Lessons from the shape bias

The goal of science is to advance our understanding of particular phenomena. However, in the field of development, the phenomena of interest are complex, multifaceted, and change over time. Here, we use three decades of research on the shape bias to argue that while replication is clearly an important part of the scientific process, integration across the findings of many studies that include variations in procedure is also critical to create a coherent understanding of the thoughts and behaviors of young children. The “shape bias,” or the tendency to generalize a novel label to novel objects of the same shape, is a reliable and robust behavioral finding and has been shown to predict future vocabulary growth and possible language disorders. Despite the robustness of the phenomenon, the way in which the shape bias is defined and tested has varied across studies and laboratories. The current review argues that differences in performance that come from even seemingly minor changes to the participants or task can offer critical insight to underlying mechanisms, and that working to incorporate data from multiple labs is an important way to reveal how task variation and a child’s individual pathway creates behavior—a key issue for understanding developmental phenomena

Does habitat stability structure intraspecific genetic diversity? It’s complicated...

Regional phylogeographic studies have long been conducted in the southeastern United States for a variety of species. With some exceptions, many of these studies focus on single species or single clades of organisms, and those considering multiple species tend to focus on deep historical breaks causing differentiation. However, in many species more recent factors may be influencing genetic diversity. To understand the roles of historic and contemporary processes in structuring genetic diversity, we reanalyzed existing genetic data from Southeast of North America using approaches gleaned from phylogeographic and landscape genetic literature that were implemented across species including AMOVAs, PCoAs, Species Distribution Modelling, and tests of isolation by distance, environment, and habitat instability. Genetic variance was significantly partitioned by ecoregions, watersheds, and across phylogeographic breaks in the majority of species. Similarly, genetic variation was significantly associated with some combination of geographic or environmental distance or habitat instability in most species. Patterns of genetic variation were largely idiosyncratic across species. While habitat instability over time is significantly correlated with genetic diversity in some species, it appears generally less important than isolation by geographic or environmental distance. Our results suggest that many factors, both historical and contemporary, impact genetic diversity within a species, and more so, that these patterns aren’t always similar in closely related species. This supports the importance of species- specific factors and cautions against assumptions that closely related species will respond to historical and contemporary forces in similar ways

Organizational Characteristics of High- and Low-Clozapine-Utilization Clinics in the Veterans Health Administration

Objective: Treatment-resistance schizophrenia occurs in 20-30% of patients. Clozapine is the only medication proven effective for treatment-resistant schizophrenia. However, less than 25% of treatment-resistant schizophrenia patients receive clozapine in most settings. Therefore, this study was conducted to identify facilitators and barriers to clozapine use, to inform development of interventions to maximize appropriate clozapine-utilization. Methods: Seventy semi-structured phone interviews were conducted with five high- and five low-utilization VA Medical Centers, from different US regions including urban and rural areas. Interviewees were key informants of clozapine processes, including mental health leadership, psychiatrists, clinical pharmacists and advanced practice nurses. Interviews were analyzed using an emergent thematic strategy to identify barriers and facilitators to clozapine prescribing. Results: Key elements associated with high-utilization included integration of non-physician psychiatric providers and clear organizational processes and infrastructure for treatment of severe mental illness (e.g. clozapine clinics, larger mental health intensive case management services). Low-utilization was associated with lack of champions to support clozapine processes and limited-capacity care systems. Obstacles identified at both high- and low-utilization sites included complex time-consuming paperwork, reliance on few individuals to facilitate processes, and issues related to transportation for patients living far from care facilities. Conclusions: Implementation efforts to organize, streamline and simplify clozapine processes, development of a multidisciplinary clozapine clinic, increasing the size and capacity of existing clinics, and provision of transportation are reasonable targets to increase clozapine utilization